Clinical trials: Hypobaric Hypoxia
Sleep-related Respiratory Disturbance
Effects of Mild Hypobaric Hypoxia on Oxygen Saturation During Sleep
Ascent to altitude lowers oxygen saturation. In addition, sleep lowers oxygen saturation at any altitude. In a prior study, we observed that sleep at 8000 feet resulted in pronounced reduction in oxygen saturation, but did not…
- Trial name
- NCT00659009
- Testing
- Reduced barometric pressure, Sea level equivalent barometric pressure
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- The Boeing Company
Hypoxia, Altitude
Analysis of Protein and Emotional Alterations During and After Hypobaric Hypoxia
This study analyses both Protein Expression and emotional alterations during hypobaric hypoxia in volunteers of different groups.
- Trial name
- DRU-EMO-K (NCT03823677)
- Testing
- Hypoxia
- Where
- Germany
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Köln
Major Depressive Disorder
Placebo-controlled Trial of 5-hydroxytryptophan and Creatine for SSRI or SNRI Augmentation in Treatment Resistant Depression in Females
The investigators propose to determine if 8 weeks of dietary augmentation with oral 5g creatine monohydrate daily and 100 mg of 5-hydroxytryptophan (5-HTP) twice daily reduces hypoxia-related depressive symptoms measured by the…
- Trial name
- NCT02922725
- Testing
- 5-hydroxytryptophan and Creatine
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Brent Michael Kious, MD, PhD
Glucose Metabolism, High Altitude
High Altitude and Exogenous Carbohydrate Oxidation
Recent studies have reported that oxidation of exogenous carbohydrate is reduced under acute hypobaric hypoxic (high altitude; HA) conditions compared to normoxia (sea level; SL) in native lowlanders.
- Trial name
- NCT03851744
- Testing
- Sea Level, High Altitude
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Traumatic Brain Injury
Exercise, Hypoxia and CPC in TBI Patients
Circulating progenitor cells (CPC) treatments may have great potential for the recovery of neurons and brain function. Our group has reported how exposure to intermittent hypobaric hypoxia with superficial muscle…
- Trial name
- TCECAM (NCT02083445)
- Testing
- cognitive activities, Exercise program, Muscle electro-stimulation
- Where
- Spain
- Volunteers
- 21 people
- Sponsor
- University of Barcelona
Baro-reflex Sensitivity, Heart Rate Variability
Low Intensity Exercise in Different Normobaric/Hypobaric Normoxic/Hypoxic Conditions.
The main goal of this project is to investigate how low intensity cycling exercise (1.5W/kg, for 6 minutes) influences cerebral functions, such as: Cerebral blood flow, oxygenation, and other physiological variables in different…
- Conditions
- Baro-reflex Sensitivity, Heart Rate Variability, EEG, Microstates, Cerebral Blood Flow Regulation
- Trial name
- Hypoxia (NCT03439202)
- Testing
- Hypoxia
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fliegerärztliches Institut