Clinical trials: Hypoglycemic Syndrome
Type 1 Diabetes
Effect of Fiber Supplementation in Children With Type 1 Diabetes
High fiber foods are recommended as a preferential source of carbohydrate by the Nutrition Study Group of the European Association for the Study of Diabetes.
- Trial name
- NCT01399892
- Testing
- soluble fiber in the form of benefiber
- Volunteers
- 10 people
- Sponsor
- Mayo Clinic
Type2 Diabetes, Elderly
Frequency of Hypoglycemia in Patients With Type 2 Diabetes Under Insulin Therapy Older Than 75 Years in Real Life
Diabetes is a chronic and progressive disease that affects nearly 3.5 million people in France. Currently the investigators are seeing an aging of the population explained by the increase in life expectancy and thus an increasing…
- Conditions
- Type2 Diabetes, Elderly, Hypoglycemia
- Trial name
- HYPOAGE (NCT03020264)
- Testing
- glycemic sensor FREESTYLE Libre Pro
- Where
- 7 sites in France
- Volunteers
- 161 people
- Sponsor
- Nantes University Hospital
Diabetes Mellitus, Hypoglycemia
Hypoglycemia Counterregulation and Symptom Perception With Insulin Detemir
Hypoglycemia and unawareness of hypoglycemia are major problems of insulin therapy in patients with diabetes mellitus. The long acting insulin analogue Detemir has structural and physicochemical properties which differ from human…
- Trial name
- NCT00490893
- Testing
- Detemir
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Primary Adrenal Insufficiency, Intermittent Fasting
Risks of Intermittent Fasting in Patients With Primary Adrenal Insufficiency
In primary adrenal insufficiency, there is an increased risk of hypoglycaemia and dehydration. These risks have been little studied particularly during intermittent fasting.
- Trial name
- NCT06299020
- Testing
- intermittent fasting
- Where
- Tunisia
- Volunteers
- 30 people
- Sponsor
- Hopital La Rabta
Critically Ill, Hypoglycemia
The Efficacy of Glucagon Like Peptide (GLP) - 1(7-36) Amide for Glycemic Control in Critically Ill Patients
The goal of this present proposal is to examine the efficacy of GLP-1 administered to control blood glucose in critically ill patients.
- Trial name
- NCT00798590
- Testing
- Glucagon-Like Peptide-1, Saline
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Johns Hopkins University
Type 1 Diabetes, Hypoglycemia
Effect of Continuous Glucose Monitoring on Course of Glucose in Type 1 Diabetes
The objective of this cross over study is to access if continuous glucose monitoring (CGMS) with a real time feed back and hypoglycemic as well as hyperglycemic glucose alerts vs.
- Trial name
- NCT00467688
- Testing
- Real time access to current glucose values during CGMS
- Where
- 2 sites in Germany
- Volunteers
- 50 people
- Sponsor
- Forschungsinstitut der Diabetes Akademie Mergentheim
Type 1 Diabetes Mellitus, Fear of Hypoglycemia
Fear of Hypoglycemia in Children and Adolecents With Type 1 Diabetes
Acute symptoms of hypoglycemia influence all aspects of every day life and reduce quality of life of children and adolescents with type 1 diabetes and their parents.
- Trial name
- NCT04454827
- Where
- Slovenia
- Volunteers
- 316 people
- Sponsor
- University of Ljubljana, Faculty of Medicine
Type 1 Diabetes Mellitus
Glucagon Counterregulation in Type 1 Diabetes
The purpose of this study is to find out whether the combination of insulin and pramlintide is better than insulin alone at helping the pancreas release glucagon in response to a low blood sugar episode.
- Trial name
- NCT03547427
- Testing
- Basal insulin alone, Basal pramlintide and reduced basal insulin, CGM
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Virginia
End Stage Renal Disease on Dialysis, Cardiac Arrhythmia
Cardiac Arrhythmia in Patients With End-Stage Renal Disease
The study will examine the presence of cardiac arrhythmias in patients receiving hemodialysis and the role of diabetes, hypoglycemia and parameters related to uremia and the dialysis procedure.
- Conditions
- End Stage Renal Disease on Dialysis, Cardiac Arrhythmia, Diabetes Mellitus, Hypoglycemia
- Trial name
- CADDY (NCT04841304)
- Testing
- Loop recorder (Reveal LINQ, Medtronic), Continuous Glucose Measurement (G6, Dexcom)
- Where
- 4 sites in Denmark
- Volunteers
- 70 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Type 1 Diabetes Mellitus, Hypoglycemia Unawareness
The Effect of Hypoglycaemia on Brain Lactate Accumulation and Cerebral Blood Flow
Iatrogenic hypoglycemia is the most frequent acute complication of insulin therapy in people with type 1 diabetes (T1DM). Recurrent hypoglycemic events initiate a process of habituation, characterized by suppression of…
- Trial name
- NCT02146404
- Testing
- hypoglycemia, euglycemia
- Where
- Netherlands
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Diabetes, Obesity
A Study of the Function of Hormones Present In Taste Buds
The purpose of this study is to find out whether the hormones in the taste buds are affected by tasting and eating food, and also whether these hormone levels are affected by an increase in body weight or type 2 diabetes.
- Conditions
- Diabetes, Obesity, Pre-Diabetes, Metabolic Syndrome
- Trial name
- NCT00233298
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Type 1 Diabetes Mellitus
Effect of Ambient Temperature on Blood Glucose and Insulin Absorption in Adults With Type 1 Diabetes
The goal of this clinical trial is to learn how different temperatures affect blood sugar levels in adults with type 1 diabetes.
- Trial name
- T1Temp (NCT07491133)
- Testing
- Environmental Temperature Exposure
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Institut de Recherches Cliniques de Montreal
Hypoglycemia
Idiopathic Reactive Hypoglycaemia and Treatment With Fructo-Oligosaccharide
Idiopathic reactive hypoglycemia (IRH) describes a condition where recurrent episodes of symptomatic hypoglycemia occurs one to four hours after a meal, usually following meals rich in carbohydrates.
- Trial name
- NCT00802971
- Testing
- FOS
- Volunteers
- 12 people
- Sponsor
- Asker & Baerum Hospital
Diabetes, Hypoglycemia
Investigating the Relationship Between Nocturnal Glucose Levels and Motion During Sleep
In this study the investigators will explore whether the motion during sleep of people with diabetes changes as a function of the blood glucose levels.
- Conditions
- Diabetes, Hypoglycemia, Hyperglycemia
- Trial name
- Moonwalk (NCT05609175)
- Where
- Switzerland
- Volunteers
- 37 people
- Sponsor
- University of Bern
Hypoglycemia, Type 1 Diabetes
A Study to Inv. Safety, Efficacy & PD of Dasiglucagon as Hypoglycemia Rescue Therapy in Children <6 Years With T1D
This research study will investigate whether dasiglucagon as a rescue therapy for participants under 6 years of age works and is safe to use.
- Trial name
- NCT05378672
- Testing
- Dasiglucagon
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- Zealand Pharma
Diabete Type 2, Hyperglycemia
Comparison of 2 Hyperglycemia-correction Scales in Hospitalized Patients
Hyperglycemia in the hospital is associated with multiple adverse outcomes. Previously, the mobile insulin scheme was used for its control.
- Trial name
- CAPADOCIA1 (NCT05752929)
- Testing
- Insulin
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Clinica San Rafael
Diabetes
The Different Response of Endocrine Hormones to Hypoglycemia in Patients With Type 1 or Type 2 Diabetes
Endocrine hormones, not only blood glucose responsive hormones, but also sexual hormones, thyroid hormones, growth hormones and so on, may have response and activites in hypoglycemia.
- Trial name
- NCT05290207
- Testing
- The hyperinsulinaemic hypoglycaemic clamp
- Where
- China
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Hypoglycemia, Inflammatory Response
Consequences of Hypoglycaemia on Cardiovascular and Inflammatory Responses
People with Type 1 diabetes (T1DM), type 2 diabetes (T2DM) and healthy volunteers will undergo a hypoglycaemic clamp to to investigate the effect of hypoglycaemia on cardiovascular and inflammatory responses.
- Conditions
- Hypoglycemia, Inflammatory Response, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- HCIR (NCT03976271)
- Testing
- hyperinsulinemic normoglycaemic-hypoglycaemic glucose clamp
- Where
- 2 sites in Denmark, Netherlands
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Type 1 Diabetes
An Outpatient Pump Shutoff Pilot Feasibility and Safety Study
The purpose of this study is to evaluate an overnight system that will turn off the insulin pump automatically if the system predicts that a low blood sugar is likely.
- Trial name
- PSO1 (NCT01736930)
- Testing
- Pump suspension
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Jaeb Center for Health Research
Type 2 Diabetes
Evaluation of Correlations Between Volatile Organic Compounds and Venous Blood Glucose in Subjects With Type 2 Diabetes
The goal of this study is to evaluate correlations between VOCs in the breath and venous blood glucose values in various glycaemic states in people living with Type 2 Diabetes.
- Trial name
- Evo (NCT06621030)
- Testing
- MIB Breath Analyzer
- Volunteers
- 15 people
- Sponsor
- BOYDSENSE