Clinical trials: Hypoglycemic Syndrome
Sleep EEG
EEG Changes of type1 Diabetes During Sleep -Insulin Induced Hypoglycemia
Hypoglycaemia is associated with characteristic changes in the EEG with the appearance of slow frequency waves. In a recent study the investigators have shown that these changes can be recorded from subcutaneous electrodes and…
- Trial name
- sleep (NCT01237509)
- Testing
- Hypo device
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- UNEEG Medical A/S
Type 2 Diabetes
Exenatide Inpatient Trial: A Randomized Controlled Pilot Trial on the Safety and Efficacy of Exenatide (Byetta®) Therapy for the Inpatient Management of Patients With Type 2 Diabetes
The purpose of this study is to try and achieve similar glycemic control in general non-Intensive Care Unit (non-ICU) patients with Type 2 Diabetes with exenatide alone or in combination with basal insulin as compared to…
- Trial name
- NCT02455076
- Testing
- Exenatide, Glargine, Rapid-acting insulin analogs
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Emory University
Type 1 Diabetes, Hypoglycemia Associated Autonomic Failure
Hypoglycemia Associated Autonomic Failure in Type 1 Diabetes Mellitus (DM)
Exercise is a cornerstone of diabetes management. It helps reduce blood pressure, promote weight loss, lower insulin resistance and improve glucose and lipid (triglyceride and HDL-cholesterol) profiles.
- Trial name
- NCT01672255
- Testing
- Fluoxetine
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Diabetes Mellitus, Type 1
Mini-Dose Glucagon to Treat Non-Severe Hypoglycemia
The purpose of this study is to determine if a small dose of glucagon (mini-dose glucagon) is effective for the treatment of non-severe hypoglycemia in adults with type 1 diabetes (T1D).
- Trial name
- NCT02411578
- Testing
- G-Pen Mini™ (glucagon injection), Glucose Tablets
- Where
- 5 sites in United States
- Volunteers
- 26 people
- Sponsor
- Jaeb Center for Health Research
Diabetes Mellitus, Type 1, Fasting
Health Education During Ramadan Fasting in Type 1 Diabetes
Adult Muslims are obliged to start fasting during the month of Ramadan. Fasting entails refraining from all food, drink, tablets and injections(vitamins \& fluids) between sunrise and sunset; a period which varies by geographical…
- Trial name
- NCT03501511
- Testing
- IDF modules, Conversational Maps
- Where
- Egypt
- Volunteers
- 53 people
- Sponsor
- Ain Shams University
Hypoglycemia, Diabetes Mellitus, Type 1
Comparison Between Hypoglycemic Counter Regulatory Responses in Type 1 Diabetics vs Control Subjects
This study compares the hypoglycemic counter regulatory response in type 1 diabetics and in healthy control subjects with and without antecedent hypoglycemia
- Trial name
- NCT03034226
- Testing
- Glucose clamp technique
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Pregnancy Preterm, Neonatal Hypoglycemia
Continuous Glucose Monitoring of Late Preterm Birth After Corticosteroids
Women undergoing late preterm birth are at high risk of delivering a newborn with neonatal hypoglycemia. The investigators plan to monitor interstitial glucose levels prior to delivery in these women in order to develop a better…
- Conditions
- Pregnancy Preterm, Neonatal Hypoglycemia, Prematurity
- Trial name
- NCT03738293
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pediatrix
Hypoglycemia, Diabetes Mellitus
Clinical Usability of Nasal Glucagon in Treatment of Hypoglycemia in Children and Adolescents
Up to fifty (50) children and adolescents with type 1 diabetes (T1D) aged 4 to ˂18 years at time of enrolment will be selected for inclusion in the study.
- Trial name
- NCT02402933
- Testing
- Nasal Glucagon
- Where
- 3 sites in United States
- Volunteers
- 26 people
- Sponsor
- Eli Lilly and Company
Hypoglycemia, Neonatal Hypoglycemia
Effects of a Hypoglycemia Protocol With Glucose Gel on Neonatal Intensive Care Unit (NICU) Admission
Evaluate if the implementation of a hypoglycemia protocol with glucose gel has reduced the NICU admission rate of neonates with low-acuity neonatal hypoglycemia.
- Trial name
- NCT04085978
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Pediatrix
Pediatric Patient (1m-21y), ICU Admission
Pediatric Intensive Care Units (ICUs) at Emory-Children's Center Glycemic Control: The PedETrol Trial
The primary goal of this project is to determine whether normalizing hyperglycemia is a safe approach to improve multisystem organ function in critically ill children requiring intensive care.
- Conditions
- Pediatric Patient (1m-21y), ICU Admission, Hyperglycemia
- Trial name
- PedETrol (NCT01116752)
- Testing
- Active Glycemic Control Strict (80-140mg/dL) vs. Conservative (190-220mg/dL) (with or without Continuous Glucose Monitoring)
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- Indiana University
Diabetes Mellitus, Type 1, Hypoglycemia
T1 Diabetes Hypoglycemia Prevention Pilot
A single center pilot study assessing the Vigilant Diabetes Management System for the prevention of recurrent mild to moderate hypoglycemia in type I diabetes patients.
- Trial name
- NCT02682940
- Testing
- Vigilant Diabetes Management Application
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- InSpark Technologies, Inc.
Type 1 Diabetes Mellitus Prone to Hypoglycemia
Artificial Pancreas With Carbohydrate Suggestion for Patients With Type 1 Diabetes Prone to Hypoglycemia
Achieving near-normoglycemia has been established as the main objective for most patients with Type 1 Diabetes (T1D). Automated insulin delivery (AID) systems, the so-called artificial pancreas (AP) or closed-loop systems, may…
- Trial name
- NCT05628662
- Testing
- Automated Insulin Delivery System (SAFE-AP)
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- Hospital Clinic of Barcelona
Neonatal Hypoglycemia, Neurodevelopmental Disorders
Neurodevelopment of Hypoglycemic Neonates
The investigators propose to prospectively conduct a neurodevelopmental evaluation of SGA and late preterm neonates who underwent risk-based screening for hypoglycemia at newborn nursery during the first 24 hours of life based on…
- Trial name
- NCT04875624
- Testing
- Bayley Scales of Infant and Toddler Development, Fourth Edition (Bayley-4)
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Montefiore Medical Center
Congenital Hyperinsulinism
Sandostatine® LP and Hyperinsulinism
To replace Sandostatine® in three daily subcutaneous injections by a single intramuscular injection of Sandostatine® LP per month in patients with a diffuse form of hyperinsulinism.
- Trial name
- NCT00987168
- Testing
- Sandostatine LP
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetes Mellitus, Type 1
Peritransplant Deoxyspergualin in Islet Transplantation in Type 1 Diabetes
Type 1 diabetes is an autoimmune disease in which the insulin-producing pancreatic beta cells are destroyed, resulting in poor blood sugar control.
- Trial name
- NCT00434850
- Testing
- Allogeneic Pancreatic Islet Cells, Deoxyspergualin, Antithymocyte globulin
- Where
- 3 sites in United States
- Volunteers
- 14 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Type 1 Diabetes Mellitus
LEA29Y (Belatacept) Emory Edmonton Protocol
Type 1 diabetes is an autoimmune disease in which the insulin-producing pancreatic beta cells are destroyed, resulting in poor blood sugar control.
- Trial name
- LEEP (NCT00468403)
- Testing
- Allogeneic Pancreatic Islet Cells, Belatacept, Basiliximab
- Where
- 2 sites in United States, Canada
- Volunteers
- 10 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Diabetes Mellitus, Type 2, Cognitive Impairment
Diabetes and Cognitive Functions in Middle Age
This study will examine the effects of type II diabetes on cognitive functions and mood in middle-aged patients. In addition, the association between cognitive functions and glycemic controls is studied in patients.
- Conditions
- Diabetes Mellitus, Type 2, Cognitive Impairment, Hyperglycemia, Hypoglycemia
- Trial name
- DBC (NCT05919927)
- Where
- Finland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Insulin Treated Type 2 Diabetes With High Risk of Hypoglycemia
Efficacy of Flash Glucose-Sensing Technology on the Occurrence of Cardiac Arrhythmias Associated With Hypoglycemia
Hypoglycemia, frequently asymptomatic, may lead to cardiac arrythmias and induce an increased risk of cardiovascular morbidity and mortality in patients with type 2 diabetes (T2D).
- Trial name
- NCT03570138
- Testing
- FREESTYLE LIBRE device, a Flash Continuous Glucose Monitoring System, Usual self monitoring Blood Glucose device
- Where
- 7 sites in France
- Volunteers
- 200 people
- Sponsor
- Poitiers University Hospital
Type I Diabetes
Monitoring of Nocturnal Hypoglycemia Using EarlySense Monitoring Device
This study observes the continuous measurement of breathing patterns, heart rate, restlessness, and tremor in sleep using the EarlySense ES 16 device as a tool in the management of hypoglycemia in pediatric type I diabetes…
- Trial name
- NCT00361608
- Testing
- EarlySense ES 16
- Where
- Israel
- Sponsor
- EarlySense Ltd.
Hypoglycemia, Type 1 Diabetes
EEG-Changes During Insulininduced Hypoglycemia in Type 1 Diabetes
The aim of this study is based on recent pilot studies carried out at Odense University Hospital showing that the acute changes in electroencephalographic (EEG) signals (i.e.
- Trial name
- NCT00810420
- Where
- Denmark
- Sponsor
- UNEEG Medical A/S