Clinical trials: Hypolactasia
Lactose Intolerance
Evaluation of the Efficacy, Durability, Safety, and Tolerability of RP-G28 in Patients With Lactose Intolerance
This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group study conducted in the United States (US) to assess the efficacy of RP-G28 compared to placebo on symptom reduction related to lactose…
- Trial name
- NCT03597516
- Testing
- RP-G28
- Where
- 35 sites in United States
- Volunteers
- 557 people
- Sponsor
- Ritter Pharmaceuticals, Inc.
Lactose Intolerance
Lactose Intolerance in Infants With Gastrointestinal Disturbances
This study enrolled thirty infants who presented by GIT symptoms and their CoMiSS was ≥ 12. The patients were assessed upon presentation, after 2 weeks of receiving lactose free diet regimen and 2 weeks after rechallenging them…
- Trial name
- NCT06789068
- Testing
- lactose free regimen
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Gastrointestinal Diseases, Cow's Milk Intolerance
Goat Milk Infant Formula Comfort Study
In this study, the investigators aim to assess that infants with mild symptoms have significantly less (severe) symptoms after 14 days goat milk-based formula use compared to infants using cow's milk-based formula supplemented…
- Trial name
- NCT06301139
- Testing
- Goat milk-based infant formula, Cow's milk-based infant formula with probiotic drops
- Where
- Spain
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Ausnutria Hyproca B.V.
Lactose Intolerance
Perceived Lactose Intolerance
The goal of this study was to examine the effects of self-perceived lactose intolerance (SPLI) as it relates to calcium intake and specific health problems that have been attributed to reduced intake of calcium and foods from the…
- Trial name
- NCT01331265
- Where
- United States
- Volunteers
- 3,815 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Lactose Intolerance
Effects of Raw Versus Other Milk Sources on Lactose Digestion
The purpose of this small, short pilot study is to determine the feasibility (e.g., recruitment, dose acceptance, retention) of a future longer trial comparing the effects of different types of milk (raw milk, cow's milk…
- Trial name
- NCT01129791
- Testing
- Raw Milk, Pasteurized Milk, Non-dairy milk
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Stanford University
Lactose Intolerance
Comparing the Inflammation, Maldigestion and Symptoms Due to Commercial Milk and A2 Milk
Cow's milk contains two types of β-casein: A1 and A2. It is evident from human clinical trials that milk with A1 protein produces more hydrogen and symptoms of lactose intolerance.
- Trial name
- NCT05660278
- Testing
- Milk containing A1 and A2 beta-casein, Milk containing only A2 beta-casein
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Purdue University
Lactose Intolerance
Screening of Lactose Intolerance Among IBS Patients Diarrhea Dominant
This cross-sectional study aims to determine the prevalence of lactose intolerance among patients with chronic diarrhea, assess its correlation with age and gender, and evaluate common symptoms in affected patients.
- Trial name
- NCT06931379
- Volunteers
- 70 people
- Sponsor
- Assiut University
Lactose Intolerance
Evaluation of LacTEST for the Diagnosis of Hypolactasia in Adults and Elderly Patients Presenting With Clinical Symptoms of Lactose Intolerance
The purpose of this study is to evaluate both the impact of LacTEST on diagnostic thinking and on patient management, and its reproducibility (Test-Retest), for the diagnosis of hypolactasia in adults and elderly patients…
- Trial name
- NCT02636413
- Testing
- gaxilose, lactose
- Where
- 6 sites in Spain
- Volunteers
- 1 people
- Sponsor
- VenterPharma
Secondary Lactose Intolerance
Comparison of the Effectiveness of Oral Lactase Enzyme and Lactose Free Formula
This study aimed to fill the gaps by comparing the effectiveness of oral lactase enzyme and lactose free formula in the management of secondary lactose intolerance in persistent and severe persistent diarrhea.
- Trial name
- NCT06827405
- Testing
- Lactase enzyme, Lactose-free formula feed
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Muhammad Aamir Latif
Functional Gastrointestinal Disorders, Lactose Intolerance
Fructose and Lactose Intolerance and Malabsorption in Functional Gastrointestinal Disorders
Background: The association of fructose and lactose intolerance and malabsorption with the symptoms of different functional gastrointestinal disorders (FGID) is unclear.
- Conditions
- Functional Gastrointestinal Disorders, Lactose Intolerance, Fructose Intolerance
- Trial name
- NCT02085889
- Testing
- no intervention: observational study
- Where
- Switzerland
- Volunteers
- 3,000 people
- Sponsor
- Brain-Gut Research Group
Lactose Intolerance
HYBRID: Hydrogen Breath Test in Lactose Digestion
The purpose of this study is to investigate the effect of a fermented infant formula on lactose digestion in lactose intolerant adults.
- Trial name
- HYBRID (NCT02703987)
- Testing
- Fermented infant milk formula, Non-fermented infant milk formula
- Where
- Singapore
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Danone Asia Pacific Holdings Pte, Ltd.
Lactose Intolerance, Irritable Bowel Syndrome
The Effects of Lactose Intolerance on Gastrointestinal Function and Symptoms in a Chinese Population
Lactose is a carbohydrate found in milk,and Lactase Deficiency (LD) is a condition in which the small intestine cannot digest this carbohydrate due to absent or insufficient amounts of lactase.Individuals with LD may be…
- Trial name
- NCT01286597
- Testing
- dietary restriction
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital
Lactose Intolerance
Effects Comparison of A1 and A2 Milk on Gastrointestinal Physiology, Symptoms and Cognitive Behavior
This is a single-site, double-blinded, randomized, controlled, 2X2 cross-over study aiming to compare effects of milk containing only A2 type beta casein versus milk containing both A1 and A2 beta casein proteins on the…
- Trial name
- NCT02406469
- Testing
- Oral consumption milk Tetra Pak
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- a2 Milk Company Ltd.
Lactose Intolerance
Incidence of Lactose Intolerance Among Self-reported Lactose Intolerant People
This is a 3-sites, double-blinded, randomized, 2X2 cross-over study aiming to compare effects of milk containing only A2 type beta casein versus milk containing both A1 and A2 beta casein proteins on the gastrointestinal symptoms…
- Trial name
- NCT02878876
- Testing
- Oral consumption of milk with sequence A1-A2, Oral consumption of milk with sequence A2-A1
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- a2 Milk Company Ltd.
Lactose Intolerant, Lactose Malabsorption
Proper Dietary Management, Follow-up, and Lactase Enzyme Supplementation for Lactose Intolerance
Lactose intolerance (LI) is considered the clinical syndrome caused by lactose malabsorption (LM). It is possible to identify four causes of lactase deficiency defining four different types of LM: primary (genetic), secondary…
- Conditions
- Lactose Intolerant, Lactose Malabsorption, Lactose Intolerance
- Trial name
- NCT06773650
- Testing
- Completion of online survey
- Where
- Italy
- Volunteers
- 385 people
- Sponsor
- European Institute of Oncology
Allergy
Althera® Versus Nutramigen / Cow's Milk Intolerance
The primary objective of this study is to demonstrate that ALTHERA® is equal or superior in efficacy than NUTRAMIGEN®
- Trial name
- NCT01727115
- Testing
- Infant Formula Feeding
- Where
- 14 sites in Belgium
- Volunteers
- 116 people
- Sponsor
- Société des Produits Nestlé (SPN)
Lactose Intolerance
Efficacy, Safety, and Tolerability Study of RP-G28 in Subjects With Lactose Intolerance
RP-G28 is being investigated for treatment of moderate to severe lactose intolerance and its potential to improve the tolerance of lactose (dairy products).
- Trial name
- NCT02673749
- Testing
- RP-G28
- Where
- United States
- Volunteers
- 377 people
- Sponsor
- Ritter Pharmaceuticals, Inc.
Small Intestinal Bacterial Overgrowth, Lactose Intolerance
Clinical Utility of Breath Tests in GI
Bloating, gas, pain and diarrhea are common complaints. Routine investigations are negative; these patients are labeled as IBS. In these patients, whether testing for carbohydrate malabsorption or small intestinal bacterial…
- Conditions
- Small Intestinal Bacterial Overgrowth, Lactose Intolerance, Fructose Intolerance, Glucose Intolerance
- Trial name
- NCT03261856
- Where
- United States
- Volunteers
- 1,080 people
- Sponsor
- Augusta University
Lactose Intolerance
Effect of a Probiotic With High Beta-galactosidase Activity on Patients With Lactose Intolerance
Lactose intolerance is a chronic disease caused by the total/partial lack of lactase production. When lactose is not properly digest, it is consumed by the microbiota.
- Trial name
- PROBIOLAC (NCT05367453)
- Testing
- Tropical juice with probiotics (B.coagulans), a Tropical juice with no probiotics, lactase tablet
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Lactose Intolerance
Effect of I31 Probiotic on Lactose Intolerance
This randomized study evaluates the usefulness of the I31 probiotic formula, against placebo, in the treatment of symptoms of lactose intolerance.
- Trial name
- NCT04164394
- Testing
- I31 Probiotic
- Where
- Mexico
- Volunteers
- 48 people
- Sponsor
- Hospital Juarez de Mexico