Clinical trials: Hyposmia
Olfactory Disorder
Steroid Nasal Irrigation for Flavor Evaluation and Detection Study
The purpose of this research study is to examine the efficacy of a 12-week smell training intervention for participants with olfactory dysfunction following an infection of the upper respiratory tract.
- Trial name
- SNIFFED (NCT02985515)
- Testing
- Smell training
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Post Acute Sequelae Covid-19 Hyposmia
Directed Topical Drug Delivery for Treatment for PASC Hyposmia
This is a phase II randomized, double-blinded, placebo-controlled study to evaluate the efficacy of topical intranasal treatment of beclomethasone vs. placebo for improved olfactory function.
- Trial name
- NCT05970731
- Testing
- Beclomethasone, Microsponge
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Duke University
COVID-19, Olfactory Disorder
Efficacy of Gabapentin for Post-Covid-19 Olfactory Dysfunction
This study will investigate the efficacy of oral gabapentin in olfactory improvement following Covid-19- associated olfactory dysfunction. This is a randomized, double-blinded, placebo-controlled trial.
- Conditions
- COVID-19, Olfactory Disorder, Anosmia, Hyposmia
- Trial name
- GRACE (NCT05184192)
- Testing
- Gabapentin gelatin capsules 300mg
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Washington University School of Medicine
Anosmia, Hyposmia
Stellate Ganglion Block for COVID-19-Induced Olfactory Dysfunction
Chronic olfactory dysfunction from the COVID-19 pandemic is a growing public health crisis with up to 1.2 million people in the Unites States affected.
- Conditions
- Anosmia, Hyposmia, Parosmia, Olfactory Disorder
- Trial name
- NCT05445921
- Testing
- Stellate Ganglion Block
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Washington University School of Medicine
Olfactory Disorder, Anosmia
Smell Changes & Efficacy of Nasal Theophylline
This study evaluates the efficacy and safety of nasal theophylline irrigation in treating smell loss related to a viral respiratory infection.
- Conditions
- Olfactory Disorder, Anosmia, Viral Infection, Theophylline Causing Adverse Effects in Therapeutic Use
- Trial name
- SCENT (NCT03990766)
- Testing
- Theophylline, Saline Nasal
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Washington University School of Medicine
Covid19, Anosmia
Smell in Covid-19 and Efficacy of Nasal Theophylline
Evidence of COVID-19 related anosmia and dysgeusia continues to accumulate daily. Currently, up to 80% of patients report subjective olfactory dysfunction (OD), and prevalence using objective olfactory testing could be even…
- Conditions
- Covid19, Anosmia, Olfactory Disorder, Covid-19 Pandemic
- Trial name
- SCENT2 (NCT04789499)
- Testing
- Theophylline Powder
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Washington University School of Medicine