Clinical trials: Hypospadias Repair
Hypospadias Repair Surgery
Urethral Mobilisation Versus Mathieu Technique for Repair of Distal Hypospadias
The aim of this research is to compare the surgical outcomes of urethral mobilization and the Mathieu technique in treating distal penile hypospadias.
- Trial name
- NCT06705699
- Testing
- Urethral mobilisation, Mathieu
- Volunteers
- 60 people
- Sponsor
- Assiut University
Pain, Hypospadias
Dexmedetomidine Infusion and Surgical Pleth Index In Pediatrics
This non-invasive dimensionless score index -SPI-reflects the Patients' sympathetic response to surgical stimulation. Its effectiveness in detecting the balance between nociceptor activation and analgesia was not only reported…
- Trial name
- NCT05727969
- Testing
- Dexmedetomidine, Lactated Ringer, Hypospadias
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Volume Overload
Perioperative Fluid Therapy in Pediatric Patients Undergoing Penile Hypospadias Repair
Optimization of perioperative fluid management is important for preventing adverse events, such as hypovolemia, cardiogenic shock, volume overload, and pulmonary edema, in both adult and pediatric patients.
- Trial name
- NCT04444089
- Testing
- lung ultrasound
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Proximal Hypospadias, Modified Duckett Urethroplasty
Hybrid Duckett vs Modified Duckett Urethroplasty for Proximal Hypospadias
proximal hypospadias presents a serious anomaly for both infants and their care givers. a variety of techniques were described through decades. None of them is completely curable.
- Trial name
- NCT06598215
- Testing
- Duckett urethroplasty
- Where
- Egypt
- Volunteers
- 43 people
- Sponsor
- Tanta University
Pediatric Disorder, Hypospadias
The Optimal Urethral Coverage in Hypospadias Repair: Dartos Fascia Versus Tunica Vaginalis Flap? A Randomized Controlled Trial
To explore the optimal urethral coverage in hypospadias repair by comparing the success rate of both covering techniques: Dartos fascia versus Tunica Vaginalis flap.
- Conditions
- Pediatric Disorder, Hypospadias, Congenital Hypospadia, Urologic Diseases
- Trial name
- NCT05123833
- Testing
- Hypospadias repair
- Where
- Egypt
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Microsurgical, Single Dartos Flap
Microsurgical Single Versus Double Dartos Flap in Distal Hypospadias Repair
This study aims to compare the surgical and functional outcomes of microsurgical single dartos flap versus double dartos flap in distal hypospadias repair.
- Conditions
- Microsurgical, Single Dartos Flap, Double Dartos Flap, Distal Hypospadias Repair
- Trial name
- NCT07676916
- Testing
- Microsurgical Single Dartos Flap, Microsurgical Double Dartos Flap
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Hypospadias
Evaluation of Double Faced Transverse Preputial Onlay Island Flap for Hypospadias Repair in Pediatrics
Evaluation of double faced transverse preputial onlay island flap for hypospadias repair in pediatrics. The preputial onlay island flap technique has been popularized for hypospadias repair as a result of offering a consistent…
- Trial name
- DFOF#TIOF (NCT05144659)
- Testing
- Double faced transverse preputial onlay island flap, Transverse inner preputial onlay island flap
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- dr. Muhammad Abdelhafez Mahmoud, MD
Hypospadias
Prophylactic Antibiotics or Placebo After Hypospadias Repair
The primary purpose of this study is to determine if routine use of prophylactic (preventive) antibiotics after repair of mid-to-distal hypospadias is beneficial.
- Trial name
- PROPHY (NCT02096159)
- Testing
- trimethoprim-sulfamethoxazole
- Where
- 2 sites in United States, Canada
- Volunteers
- 93 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Hypospadias
Effect of Caudal and Penile Block on Hypospadias Repair Complications
Hypospadias is one of the most common genitourinary (GU) malformations, seen in approximately 1 of 250 male live births. Common methods of local anesthesia administration for hypospadias surgery include caudal and dorsal penile…
- Trial name
- NCT02851290
- Testing
- Caudal block anesthesia, Dorsal penile nerve block anesthesia
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Baylor College of Medicine
Dexmedetomidine Infusion, Pediatric
Comparison of Caudal Block Versus Dexmedetomidine Infusion in Pediatric Patients Undergoing Hypospadias Repair Surgery
Pain is one of the most misunderstood, underdiagnosed, and untreated medical problems, particularly in children. New Joint Commission on Accreditation of Health Care Organization regards pain as fifth vital sign and requires…
- Conditions
- Dexmedetomidine Infusion, Pediatric, Hypospadias Repair Surgery
- Trial name
- NCT04331418
- Testing
- Dexmedetomidine, caudal block
- Where
- Egypt
- Volunteers
- 135 people
- Sponsor
- Tanta University
Hypospadias
Long Term Outcome of Hypospadias Repair
Hypospadias is a common congenital abnormality of the penis which affects approximately 1 boy in 250. The opening of the urethra is located on the undersurface of the penis rather than the tip,the foreskin is deficient and there…
- Trial name
- NCT02103712
- Testing
- Qualitative
- Where
- United Kingdom
- Volunteers
- 170 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Hypospadias, Hypospadias, Coronal
Penile Ischemia for Hypospadias Repair and The Patients and Surgeons Reported Outcomes
Although haemostasis aimed to maintain bloodless surgical field for better exposure for the surgeon, cosmetic impact, and decreased breakdown of repair, there is no trials regarding the impact of haemostasis techniques on surgeon…
- Conditions
- Hypospadias, Hypospadias, Coronal, Hypospadia, Repair, Tourniquet
- Trial name
- NCT04239066
- Testing
- Tourniquet, Non-tourniquet
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University
Hypospadias, Urethrocutaneous Fistula
Does Caudal Block Increase the Incidence of Urethrocutaneous Fistula Formation Following Hypospadias Repair in Infants?
This is a prospective randomized multi-center non-inferiority trial conducted through the Pediatric Regional Anesthesia Network study sites to determine if caudal block increases the incidence of urethrocutaneous fistula…
- Trial name
- NCT02861950
- Testing
- Caudal block with ropivacaine, penile nerve block with bupivacaine
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- University of Colorado, Denver
Hypospadias Repair Surgery
Comparison of the Efficacy of Bupivacaine with and Without Dexmedetomidine As an Adjuvant on Penile Block for Postoperative Pain Relief in Pediatrics Undergoing Hypospadias Repair Surgery
The main issue with pain management in children especially young children is the difficulty involved in evaluating it. When a patient's level of pain cannot be accurately assessed, effective analgesia cannot be prescribed.
- Trial name
- NCT06789393
- Testing
- Dexmedetomidine, Bupivacaine
- Volunteers
- 80 people
- Sponsor
- Assiut University
Hypospadias
Modified Second Layer Repair for Distal Penile Hypospadias
to evaluate a modification to snodgrass technique in second layer closure of distal penile hypospadias
- Trial name
- NCT05253456
- Testing
- Derma -Dartos Flap for second layer closure
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Ain Shams University
Post Operative Pain
Nalbuphine Plus Caudal Bupivacaine in Hypospadius Repair
Caudal aneasthesia for pediatric surgery was first reported in 1933. Since then, studies have described the indications for pediatric caudal block, the level of analgesia, doses, advantages and disadvantages of this technique.
- Trial name
- NCT03476772
- Testing
- Nalbuphine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Hypospadias Repair, Pediatric Anesthesia
Caudal vs Dorsal Penile Nerve Block for Postoperative Analgesia in Children Undergoing Hypospadias Repair (CaD-DPNB)
This prospective, randomized clinical trial conducted at Ain Shams University Hospitals evaluated the analgesic efficacy of dorsal penile nerve block versus caudal epidural block in 30 male children undergoing primary hypospadias…
- Conditions
- Hypospadias Repair, Pediatric Anesthesia, Postoperative Analgesia
- Trial name
- CaD-DPNB (NCT07306806)
- Testing
- Caudal epidural block, Dorsal Penile nerve Block
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Hypospadias, Caudal Block
Effect of Caudal Block on Urethrocutaneous Fistula After Distal Hypospadias Repair
Hypospadias is one of the most common congenital urogenital anomalies in males, occurring in approximately 1 in every 200-300 male births.
- Conditions
- Hypospadias, Caudal Block, Pediatric Anesthesia
- Trial name
- NCT07675798
- Testing
- Caudal Block, General Anesthesia without Caudal Block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Hypospadias, Penoscrotal, Chordee
Transverse Preputial Island Flap Versus Double Faced Preputial Flap for Repair of Penoscrotal Hypospadias With Chordee
The purpose of this study is to compare the outcomes and complications of the transverse preputial island flap (Duckett's procedure) to those of double-faced preputial flap (DFPF) for one-stage repair of penoscrotal hypospadias…
- Trial name
- DuckettvDFPF (NCT04605068)
- Testing
- Transverse preputial island flap (Duckett's technique), Double-faced preputial flap (DFPF)
- Volunteers
- 144 people
- Sponsor
- dr. Muhammad Abdelhafez Mahmoud, MD
Penile Hypospadias
Pearls and Pitfalls in Usage of Plasma-Rich Platelet Graft Versus Dartos Flap in Distal Penile Hypospadias Repair
Hypospadias is the most common congenital anomaly of penis. It is the second most common genital birth defect in boys after cryptorchidism The reinforcement of hypospadias repair with an intermediate layer is believed to reduce…
- Trial name
- NCT06808139
- Testing
- Plasma-Rich Platelet Graft, Dartos Flap
- Volunteers
- 70 people
- Sponsor
- Assiut University