Clinical trials: Hypotension, Controlled
Middle Ear Disease
The Effect of Tranexamic Acid in Endoscopic and Microscopic Ear Surgery Cases on Surgeon Satisfaction
By using tranexamic acid, an antifibrinolytic drug, the aim is to prevent the restriction of the field of view of the surgical field due to bleeding in middle ear microscopic and endoscopic surgery operations in which controlled…
- Trial name
- NCT06434636
- Testing
- Transamine 10% IV/IM Solution for Injection, %0.9 Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Adverse Effect
Intensive Versus Standard Treatment for Hypotension on Maternal Hemodynamics in Preeclamptic Patients
The objective of this study is to investigate the impact of varying maternal blood pressure maintenance targets on maternal hemodynamics in preeclamptic patients following cesarean section.
- Trial name
- NCT06151444
- Testing
- Alpha-Agonist, α-adrenergic receptor agonist
- Volunteers
- 160 people
- Sponsor
- General Hospital of Ningxia Medical University
Cesarean Section, Postoperative Nausea and Vomiting (PONV)
Restrictive vs Liberal Intraoperative Fluid Strategy and Postoperative Outcomes After Elective Cesarean Section
Spinal anesthesia for elective cesarean section is frequently associated with hemodynamic instability and postoperative complications such as postoperative nausea and vomiting (PONV) and delayed gastrointestinal recovery.
- Conditions
- Cesarean Section, Postoperative Nausea and Vomiting (PONV), Postdural Puncture Headache (PDPH), Postoperative Ileus
- Trial name
- NCT07440667
- Testing
- Restrictive intraoperative crystalloid fluid strategy (≤3 mL/kg/h), Liberal intraoperative crystalloid fluid strategy (>3 mL/kg/h)
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Nigde Omer Halisdemir University
Adverse Effect
Norepinephrine Prophylaxis for Postspinal Anesthesia Hypotension in Parturients With Preeclampsia.
The purpose of this study is to investigate the suitable infusion dose of norepinephrine for prophylaxis against postspinal anesthesia hypotension in parturients with preeclampsia undergoing cesarean section.
- Trial name
- NCT04556370
- Testing
- Normal saline, Norepinephrine
- Where
- China
- Volunteers
- 180 people
- Sponsor
- General Hospital of Ningxia Medical University
Hypotension, Anesthesia; Adverse Effect, Spinal and Epidural
ONDANSETRON AND EFFECTIVE DOSE IN 50% OF SUBJECTS OF PROPHYLACTIC NOREPINEPHRINE INFUSIONS FOR PREVENTING SPINAL ANESTHESIA-INDUCED HYPOTENSION DURING CESAREAN DELIVERY
Spinal anesthesia is the preferred technique for elective cesarean section as per ASA guidelines. Hypotension is the main complication of this technique and is secondary to both sympatholysis and its associated decrease in…
- Conditions
- Hypotension, Anesthesia; Adverse Effect, Spinal and Epidural, Cesarean Section
- Trial name
- NCT04703088
- Testing
- Ondansetron 4 MG, 0.9% Saline
- Volunteers
- 60 people
- Sponsor
- Laval University
Hypotension
Avoiding Hypotension in Preterm Neonates
Objectives Firstly to examine in preterm neonates, whether it is possible to reduce number of hypotensive episodes and use of catecholamines by applying cerebral/peripheral near infrared spectroscopy in combination with…
- Trial name
- AHIP (NCT01910467)
- Testing
- NIRS visible and predefined interventions, NIRS not visible and treatment as usual
- Where
- Austria
- Volunteers
- 98 people
- Sponsor
- Medical University of Graz
Post Spinal Anaesthesia Hypotension, Transurethral Resection of the Prostate (TURP)
Ultrasound Assessment of Femoral Vein and Inferior Vena Cava Collapsibility to Predict Spinal Anesthesia-Induced Hypotension
Spinal anesthesia is commonly used in transurethral prostate resection (TUR-P) surgeries; however, post-spinal hypotension remains a frequent and clinically significant complication, particularly in elderly patients.
- Trial name
- NCT07497295
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people
- Sponsor
- Antalya Training and Research Hospital
Hypovolemia
Effect of Preoperative Fluid Therapy on Post-induction Hypotension
Although preoperative dehydration is a known risk factor for post-induction hypotension, evidence regarding preemptive weight-based fluid therapy remains limited.
- Trial name
- NCT06231472
- Testing
- weight-based fluid therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Mustafa Burgac
Spinal Cord Injury
Mechanisms of Arterial Hypotension in Chronic Spinal Cord Injury
This clinical study is designed to investigate the mechanisms of blood pressure regulation and respiratory motor function affected by spinal cord injury (SCI).
- Trial name
- NCT02154412
- Testing
- Respiratory Training
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Hypotension (MeSH: D007022), Bradycardia
Prophylactic Ondansetron and Maternal Hemodynamics During Spinal Anesthesia for Elective Cesarean Section
Spinal anesthesia is the preferred technique for elective cesarean section, but it is frequently complicated by maternal hypotension and bradycardia.
- Trial name
- NCT07883772
- Testing
- Ondansetron
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Aydin Adnan Menderes University
Nasolacrimal Duct Obstruction
The Efficacy of Dexmedetomidine Versus Labetalol In Providing Controlled Hypotension In Dacryocystorhinostomy SurgeryA Comparative Randomized Prospective Study
The most important symptoms of nasolacrimal duct obstruction are excessive tearing and mucoid discharge. The proposed treatment in this regard is dacryocystorhinostomy (DCR) surgery.
- Trial name
- NCT06346561
- Testing
- Dexmedetomidine, Labetalol
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Hypotension, Ischemia Reperfusion Injury
Intermittent Portal and Graft Purge in Living Donor Liver Transplantation
Post-reperfusion syndrome and ischemia-reperfusion insult are a common well-known complication in liver transplantation. Several trials investigated variables that my contribute to the generation of these two complications for…
- Trial name
- IPLDLT (NCT02845154)
- Testing
- bolus purge, Intermittent purge
- Where
- 3 sites in Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Hypotension During Surgery
Comparison of General Anesthesia Hemodynamics Between R and P in Patients Undergoing Laparoscopic Hepatectomy
This study is a randomized controlled trial designed to investigate the effects of two anesthetics, remimazolam and propofol, on intraoperative hemodynamics in patients undergoing laparoscopic liver resection.
- Trial name
- NCT06714669
- Testing
- propofol, Remimazolam
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Sun Yat-sen University
Hypotension, Controlled, Anaesthesia, Spinal
Non Invasive Haemodynamics in Neuraxial Anaesthesia Hypotension
Spinal (or neuraxial) anaesthesia is still considered the first choice technique for elective Caesarean section as simple, quick, reliable and cheap.
- Conditions
- Hypotension, Controlled, Anaesthesia, Spinal, Caesarean Section
- Trial name
- NIHNAH (NCT03653442)
- Where
- Italy
- Volunteers
- 55 people
- Sponsor
- Papa Giovanni XXIII Hospital
Spinal Anesthesia Induced Hypotension
The Ability of Perfusion Index and Positional Perfusion Index Variation to Predict Spinal Anesthesia-induced Hypotension in Elderly Patients
In this study, we will test the ability of positional perfusion index variation to predict post-spinal anesthesia hypotension in elderly patients.
- Trial name
- NCT05259124
- Testing
- positional perfusion index variation
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Cairo University
Sepsis
Study of Treatment's Echocardiographic Mechanisms
This ancillary study determines whether the Crystalloid Liberal or Vasopressors Early Resuscitation in Sepsis (CLOVERS) [ClinicalTrials.gov Identifier: NCT03434028] treatment arms (restrictive fluids strategy vs.
- Trial name
- NCT03913403
- Testing
- ECHO, Blood Draw
- Where
- 7 sites in United States
- Volunteers
- 210 people
- Sponsor
- Intermountain Health Care, Inc.
Postoperative Cognitive Dysfunction (POCD), Controlled Hypotension for Nasal Surgeries
Comparison of Desflurane, Sevoflurane, and Total Intravenous Anesthesia in Ear Surgery Under Controlled Hypotension
This randomized prospective study aimed to compare desflurane, sevoflurane, and total intravenous anesthesia methods in patients undergoing elective ear surgery under controlled hypotension, with a particular focus on…
- Trial name
- POCD-ENT (NCT07792759)
- Testing
- Desflurane, Sevoflurane, Remifentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Post-induction Hypotension, Lidocaine
Lidocaine-based Versus Opioid-based Induction of Anesthesia in Emergency Laparotomy
Lidocaine-based anesthesia had been recently reported as a successful regimen for induction of anesthesia in elderly population with better hemodynamic profile than opioid-based induction.
- Conditions
- Post-induction Hypotension, Lidocaine, Opioid, Emergency Laparotomy
- Trial name
- NCT06772727
- Testing
- Lidocaine, Fentanyl, Propofol
- Where
- Egypt
- Volunteers
- 149 people
- Sponsor
- Cairo University
Spinal Cord Injury, Autonomic Dysreflexia
Treatment of Post-SCI Hypotension
While treatment strategies for OH have been identified for use in persons with acute SCI, the field of SCI medicine lacks a gold standard for treatment thresholds and well-defined outcome parameters.
- Conditions
- Spinal Cord Injury, Autonomic Dysreflexia, Orthostatic Hypotension, Baroreceptor Integrity
- Trial name
- NCT02919917
- Testing
- Midodrine Hydrochloride
- Where
- 2 sites in United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Spinal Anesthesia-Induced Hypotension
Predictors of Spinal Anesthesia-Induced Hypotension in Hypertensive Patients
This prospective observational study aims to evaluate predictive factors for spinal anesthesia-induced hypotension (SASH) in hypertensive patients undergoing elective surgery.
- Trial name
- NCT06749184
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Konya City Hospital