Clinical trials: Hypotension
Percutaneous Nephrolithotomy
Effect of Ondansetron on Spinal-induced Hypotension for Percutaneous Nephrolithotomy
Percutaneous nephrolithotomy (PCNL) is the surgical standard for treating large or complex renal stones. The stones are removed by passing a small telescope through the side of the patient directly into the kidney, so the stone…
- Trial name
- NCT04891484
- Testing
- Ondansetron group, Saline group
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
Dialysis Hypotension
Steroids on Intra-dialytic Hypotension
Symptomatic hypotension during (or immediately following) hemodialysis complicates 5 to 30 percent of all dialysis treatments and is associated with increased morbidity and mortality.
- Trial name
- NCT03465007
- Testing
- Hydrocortisone, Normal saline
- Where
- Jordan
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Hypotension
The Severity Of Hypotension Comparing Three Positions During Spinal Anesthesia For Cesarean Delivery
The investigators intend to study the impact of patient positioning on the changes in blood pressure after spinal anesthesia for cesarean delivery.
- Trial name
- NCT02146898
- Testing
- Position
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Beth Israel Deaconess Medical Center
Intraoperative Hypotension
Hypotension Prediction Index (HPI) and Assisted Fluid Management (AFM) for Perioperative Hemodynamic Optimization in Patients Under General Anesthesia
This study investigates if the Hypotension Prediction Index (HPI) combined with the Assisted Fluid Management (AFM) software can improve perioperative hemodynamic management in adult patients undergoing general anesthesia.
- Trial name
- NCT07301307
- Testing
- Acumen IQ sensor with Hypotension Prediction Index (HPI) and Assisted Fluid Management (AFM) software, Conventional Intraoperative Hemodynamic management
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- National and Kapodistrian University of Athens
Hypotension, ENT Disease
Influence of the "Hypotension Probability Index" on Intraoperative and Postoperative Hypotension in ENT- and OM-Surgery
The aim of the project is to investigate whether the use of the HPI can reduce the number and duration of intra- and postoperative hypotension in ventilated patients during and two hours after extensive surgery in the head and…
- Conditions
- Hypotension, ENT Disease, Acute Kidney Injury, Anesthesia
- Trial name
- NCT04151264
- Testing
- Hypotension probability index (HPI)
- Where
- Germany
- Volunteers
- 75 people
- Sponsor
- University of Giessen
Cirrhosis With Septic Shock
Comparison And Outcomes Of Fluid Resucitation With 0.9% Normal Saline And 5% Albumin In Cirrhosis Patients With Sepsis Induced Hypotension
300 consecutive patients with cirrhosis of any aetiology admitted with features of sepsis and sepsis induced hypotension to the intensive care unit, the emergency department and the step down units of Institute of Liver and…
- Trial name
- NCT02462902
- Testing
- 5% albumin Infusion, 0.9% sodium chloride solution
- Where
- India
- Volunteers
- 308 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Oxygen Saturation
Comparison of Volatile Anesthetics on Cerebral Oxygenation During Controlled Hypotension
Controlled hypotension is a preferred method for reducing surgical bleeding during septoplasty operations however, the level of hypotension and bradycardia should not disrupt cerebral oxygenation.
- Trial name
- NCT02834845
- Testing
- Sevoflurane, Desflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people
- Sponsor
- Ufuk University
Hypotension, Pregnancy Related
Non-invasive Haemodynamic Monitoring to Predict Spinal Hypotension During Caesarian Section
Spinal anaesthesia for elective caesarean section is associated with maternal hypotension, secondary to alteration of sympathetic tone and hypovolemia, in up to 70% of cases.
- Conditions
- Hypotension, Pregnancy Related, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
- Trial name
- NCT04608227
- Testing
- Clearsight monitoring
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hospital Nord
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, Chronic Fatigue Syndrome
The Exercise Response to Pharmacologic Cholinergic Stimulation in Myalgic Encephalomyelitis / Chronic Fatigue Syndrome
Myalgic encephalomyelitis/Chronic fatigue syndrome (ME/CFS), otherwise known as Chronic fatigue syndrome (CFS) or myalgic encephalomyelitis (ME), is an under-recognized disorder whose cause is not yet understood.
- Conditions
- Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, Chronic Fatigue Syndrome, Myalgic Encephalomyelitis, Exercise Intolerance
- Trial name
- NCT03674541
- Testing
- Pyridostigmine Bromide
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Brigham and Women's Hospital
Parkinson Disease (PD), REM Sleep Behavior Disorder (iRBD)
Artificial Intelligence-based Parkinson's Disease Risk Assessment (AI-PRA) Study
The study aims to provide initial proof-of-concept validation data of an artificial intelligence-based model to estimate individual Parkinson's disease risk using demographic, clinical, genetic information and digital biomarker…
- Conditions
- Parkinson Disease (PD), REM Sleep Behavior Disorder (iRBD), Neurogenic Orthostatic Hypotension, Hyposmia
- Trial name
- AI-PRA (NCT07706829)
- Testing
- Smartwatch and phone app
- Where
- 3 sites in France, Spain and 1 more
- Volunteers
- 60 people
- Sponsor
- Queen Mary University of London
Hemodynamic
A PREDICTIVE ALGORITHM IN AORTIC SURGERY
We will enroll patients scheduled for abdominal aortic aneurysm repair and divide in two groups; in the control group the hemodynamic optimization will be made based on standard cardiovascular parameters showed in the Hemosphere…
- Trial name
- HYVAS (NCT06984302)
- Testing
- proactive therapy
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Hypotension
Transcutaneous Electrical Acupoint Stimulation(TEAS) for Hypotension After Spinal Anesthesia in Parturients
The purpose of this study is to compare the effect of TEAS on hypotension after spinal anesthesia in patients undergoing cesarean section
- Trial name
- THSAP (NCT01930227)
- Testing
- TEAS, Non-acupoint stimulation
- Where
- 2 sites in China
- Volunteers
- 150 people
- Sponsor
- wangqiang
Septic Shock, Fluid Therapy
Fluid Balance in the ICU - Interventions to Minimize Fluids in Patients With Septic Shock
The purpose of the study is to determine if a protocol that assesses patients' daily fluid intake and output can decrease the overall amount of fluid patients receive during the first five days in the ICU.
- Conditions
- Septic Shock, Fluid Therapy, Hypotension
- Trial name
- NCT02473718
- Testing
- Fluid minimization protocol, Ultrasound
- Volunteers
- 82 people
- Sponsor
- Washington University School of Medicine
Hypotension
Use of Ultrasonography to Determine Fluid-responsiveness for Shock in a Population of Intensive Care Unit Patients
The objective of our study is to determine the correlation of transthoracic ultrasonographic indices of fluid responsiveness to changes in direct measures of cardiac output and to compare them to other established predictors of…
- Trial name
- NCT01680770
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- University of Chicago
Ocular Hypotension
Clinical Evaluation of CATS Tonometer Prism
Prospective, open-labeled, randomized, controlled, multicenter study at two clinical investigative sites in Tucson, Arizona. The subjects will undergo intraocular pressure measurement with the CATS tonometer prism and the…
- Trial name
- NCT02990169
- Testing
- CATS tonometer prism, Goldmann Tonometer prism
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Intuor Technologies, Inc.
Hypotension After Spinal Anesthesia
Lingual Ondansetron in Reduction of Spinal Hypotension in Cesarean Section
The goal of this clinical trial is to learn if drug ondansetron, used in lingual form, lowers the incidence of spinal anesthesia-induced hypotension in cesarean sections. It will also learn about the safety of drug ondansetron.
- Trial name
- NCT07037654
- Testing
- ondansetron lingual film
- Where
- Egypt
- Volunteers
- 112 people
- Sponsor
- Suez Canal University
Shock
Extension of the RUSH Protocol for Volume Responsiveness
The current study plants to create a patient registry of patients who present to the emergency department with signs and symptoms of shock and evaluate the ability of a multi-step cardiopulmonary ultrasound protocol to determine…
- Trial name
- NCT03285269
- Testing
- Ultrasound Protocol, Bioreactance, Passive Leg Raise
- Sponsor
- Kaiser Permanente
Spinal Induced Hypotension
Ephedrine Versus Ondansetron During Cesarean Delivery
More than 30% of the patients receiving spinal anesthesia develop hypotension. Hypotension developed during cesarean section (C/S) under spinal anesthesia may jeopardize uteroplacental circulation leading to fetal compromise and…
- Trial name
- NCT05127876
- Testing
- Ondansetron 4 MG, Ondansetron 8mg, EPHEDrine 10 Mg/mL-NaCl 0.9% Intravenous Solution
- Where
- Egypt
- Volunteers
- 168 people
- Sponsor
- Ain Shams University
Caesarean Section
The Pleth Variability Index and Hypotension at Caesarean Under Spinal.
During a caesarean section the blood pressure is usually measured every few minutes and it may fall too quickly to be detected in a timely fashion by this intermittent means.
- Trial name
- NCT02285569
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Hypotension, Sepsis
Carotid Doppler Ultrasound for the Measurement of Intravascular Volume Status
Ultrasound represents an attractive non-invasive method to assess hemodynamic status. Understanding dynamic changes in hemodynamics in situations such as hypovolemia, sepsis, and cardiogenic shock can potentially help improve…
- Trial name
- NCT02907931
- Testing
- Point of Care Ultrasound
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Yale University