Clinical trials: Hypotension Drug-Induced
Pruritis, Hypotension Drug-Induced
Incidence of Pruritus Using Intrathecal Fentanyl Versus Epidural Fentanyl to Initiate Labour Analgesia.
The purpose of this study is to investigate the effect of neuraxial analgesia initiation on the incidence of pruritus in laboring women.
- Conditions
- Pruritis, Hypotension Drug-Induced, Urinary Retention, Fetal Bradycardia During Labor
- Trial name
- NCT07187427
- Testing
- Spinal analgesia, Epidural Analgesia
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- St. Justine's Hospital
Hip Fractures, Anesthesia
Fractional Spinal Anesthesia and Systemic Hemodynamics in Frail Elderly Hip Fracture Patients.
Aging and frailty make the elderly patients susceptible to hypotension following spinal anaesthesia. The systemic haemodynamic effects of spinal anaesthesia are not well known.
- Conditions
- Hip Fractures, Anesthesia, Hypotension Drug-Induced, Cardiac Output, Low
- Trial name
- NCT05101291
- Testing
- Bupivacain
- Where
- Sweden
- Volunteers
- 15 people
- Sponsor
- Sahlgrenska University Hospital
Hypotension Drug-Induced
Is Labetalol More Effective Than Metoprolol for Controlled Hypotensive Anesthesia During Endoscopic Nasal Surgeries?
Background: Mucosal bleeding is the most frequent complication with endoscopic nasal surgeries, as it interferes with the optimal visualization of the intranasal anatomy, leading to increased complications, operation duration…
- Trial name
- NCT05368376
- Testing
- Labetalol Hydrochloride Oral Tablet, Metoprolol Tartrate Oral Tablet
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Damanhour Teaching Hospital
Blood Pressure, Hypotension Drug-Induced
Comparison Between Inhalation and Intravenous Induction of Anaesthesia During Interventional Mitral Valve Repair
The induction of anaesthesia is one of the most critical situations for high-risk-patients undergoing interventions surgery. For several reasons, it is crucial to maintain adequate blood pressure and cardiac output during this…
- Trial name
- COMPETENT (NCT04865614)
- Testing
- Etomidate, Sevoflurane
- Where
- Germany
- Volunteers
- 57 people
- Sponsor
- Heidelberg University
Hypertension, Frailty
The Effects of Medication Induced Blood Pressure Reduction on Cerebral Hemodynamics in Hypertensive Frail Elderly
Rationale: Systolic hypertension represents the leading risk for burden of disease among older adults (age >70 years), with an increasing prevalence due to the increase in lifespan.
- Conditions
- Hypertension, Frailty, Old Age; Dementia, Orthostatic Intolerance
- Trial name
- BLUEBERRY (NCT05529147)
- Testing
- Antihypertensive Agents
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- Radboud University Medical Center
Postoperative Nausea and Vomiting (PONV), Postoperative Pain
Effect of Timing of Dexamethasone During Induction on Postoperative Outcomes
This study aims to investigate how the timing of dexamethasone administration during anesthesia induction affects patient outcomes after surgery.
- Conditions
- Postoperative Nausea and Vomiting (PONV), Postoperative Pain, Inflammatory Response to Wounding, Hyperglycemia Drug Induced
- Trial name
- TIDE (NCT06685991)
- Testing
- Dexamethasone
- Volunteers
- 300 people
- Sponsor
- AABDI Mohammed
Drug-induced Hypotension
Study of Maraviroc (MVC) and Epzicom (ABC/3TC) Once-Daily in ART-Naive & First Switch Patients
Hypotension does not occur with Maraviroc at a dose of 600 mg/day
- Trial name
- NCT02626923
- Volunteers
- 51 people
- Sponsor
- Nicholaos C Bellos, MD
Blood Pressure, Low
Induction Agent and Incidence of Hypotension in Heart Failure Patients Undergoing LVAD-Implantation
The induction of anesthesia is one of the most critical situations for high-risk-patients undergoing major surgery. For several reasons, it is crucial to maintain adequate blood pressure and cardiac output during this phase.
- Trial name
- INTENS (NCT04934410)
- Testing
- Etomidate, Midazolam, Sevoflurane
- Volunteers
- 50 people
- Sponsor
- Heidelberg University
Respiratory Depression, Hypoxemia
Dexmedetomidine vs Propofol in High-Risk ERCP Patients
ERCP requires deep sedation due to pain and discomfort, but propofol-commonly used with opioids-often causes respiratory and cardiovascular complications, especially in elderly or high-risk patients.
- Conditions
- Respiratory Depression, Hypoxemia, Hypotension Drug-Induced, Bradycardia
- Trial name
- NCT07166614
- Testing
- dexmedetomidin, Propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Hypotension Drug-Induced, General Anesthesia Using Endotracheal Intubation
Alveolar Recruitment Maneuver-Induced Hypotension: A Dynamic Consequence and Intraoperative Indicator of Fluid Responsiveness
This study investigates whether two simple bedside tests - the Passive Leg Raising (PLR) test and the Pleth Variability Index (PVI) - can predict a drop in blood pressure that sometimes occurs during a lung-opening procedure…
- Conditions
- Hypotension Drug-Induced, General Anesthesia Using Endotracheal Intubation, Atelectasis, Fluid Responsiveness
- Trial name
- NCT07766967
- Testing
- Alveolar Recruitment Maneuver (ARM), Passive Leg Raising (PLR) Test
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- University of Health Sciences Balikesir Hospital Eduation and Research
Post Operative Analgesia, Bradycardia
Comparison of Supra vs Infra Inguinal Fascia Iliaca Blocks for Spinal Positioning and Analgesia in Lower Limb Surgery
Severe pain associated with thigh and knee fractures makes the positioning for regional anesthesia a challenge. Different modalities to make patient pain free for spinal positioning, post op analgesia and patient satisfaction…
- Conditions
- Post Operative Analgesia, Bradycardia, Hypotension Drug-Induced
- Trial name
- 27G (NCT07221682)
- Testing
- USG GUIDED SUPRA-INGUINAL FASCIA ILIACA BLOCK, USG GUIDED INFRA-INGUINAL FASCIA ILIACA BLOCK
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Sahiwal medical college sahiwal
Hypotension Drug-Induced, Cerebral Oxygen Saturation
Effect of Controlled Hypotension on Cerebral Oxygen Saturation
For a successful functional endoscopic sinus surgery (FESS), it is crucial to provide effective controlled hypotension to reduce blood loss and provide a relatively blood-free surgical environment to facilitate surgery.
- Trial name
- NCT02967029
- Testing
- Esmolol Hydrochloride, Remifentanil Hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Rapid Sequence Induction
Best Hypnotic Drug Choice for Rapid Sequence Induction in the Operating Room
The best hypnotic choice to optimize the balance between good intubation condition quality and hemodynamic stability during RSI performed in the operating theatre remained to be investigated.
- Trial name
- HYPNOTIKS (NCT06733129)
- Testing
- direct IV injection, combination of Ketamine and Propofol
- Where
- 20 sites in France
- Volunteers
- 1,218 people
- Sponsor
- Nantes University Hospital
Paracetamol, Hypotension Drug-Induced
Hemodynamic Effects of Intravenous Paracetamol in Patients Undergoing Emergency Laparotomy
Emergency laparotomy is a high-risk procedure often performed in patients with severe physiological derangements due to sepsis, making perioperative management challenging.
- Conditions
- Paracetamol, Hypotension Drug-Induced, Emergency Surgery
- Trial name
- NCT07466108
- Testing
- Paracetamol (acetaminophen)
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Hypotension Drug-Induced
Premedication With Atenolol Versus Metoprolol for Controlled Hypotensive Anesthesia During Nasal Surgeries
Objectives: To compare the safety and efficacy of oral atenolol versus oral metoprolol as a premedication for controlled hypotensive anesthesia during nasal surgeries.
- Trial name
- NCT04914234
- Testing
- Atenolol Succinate Oral Tablet, Metoprolol Succinate Oral Tablet
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Damanhour Teaching Hospital
Hypotension Drug-Induced
Maternal Lateral Tilt and Cardiac Output in Caesarean Section
Background: Left uterine displacement (LUD) has been questioned as an effective strategy to prevent aortocaval compression after spinal anesthesia (SA) for cesarean delivery (CD).
- Trial name
- NCT05143684
- Testing
- Left Lateral Uterine Displacement
- Where
- Italy
- Volunteers
- 46 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS