Clinical trials: Hypotension During Surgery
Post Induction Hypotension
Comparing the Hemodynamic Effects of Volume Loading vs Non-loading During Induction of Anesthesia in Fluid Responder Patients With Coronary Artery Disease Undergoing Elective Coronary Artery Bypass Graft Surgery: a Randomized Controlled Study.
All preoperative cardiac medications will be continued till the morning of the surgery, except angiotensin converting enzyme inhibitors.
- Trial name
- NCT05462847
- Testing
- Ringer acetate
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Kasr El Aini Hospital
Hypotension, Hypertension
Oliceridine Versus Sufentanil for Blood Pressure Control During Anesthesia Induction in Older Women With Hypertension Undergoing Gynecological Laparoscopic Surgery
Blood pressure can fall during the start of general anesthesia, particularly in older patients with high blood pressure. This study compared two medicines, oliceridine and sufentanil, to assess their effects on low blood pressure…
- Trial name
- NCT07871500
- Testing
- Oliceridine, Sufentanil
- Where
- China
- Volunteers
- 134 people
- Sponsor
- Xingguo Xu
Hypotension, Orthostatic, Total Hip Replacement
Study on Baroreceptor Function in Relation to Orthostatic Blood Pressure Regulation After Hip Surgery
The purpose of this observational study is to evaluate the baroreceptor function in relation to surgical inflammation and orthostatic intolerance after elective hip arthroplasty.
- Trial name
- NCT01866787
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Postinduction Hypotension, Hypotension During Surgery
The Effect of Preoperative Intravenous Fluid Bolus on Post-induction Hypotension in Elective Cystoscopies.
This study aims to determine whether a standardized, weight-based crystalloid fluid bolus administered preoperatively reduces the incidence of postinduction hypotension (PIH) in patients undergoing cystoscopy.
- Trial name
- NCT06985654
- Testing
- Lactated Ringers
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Missouri-Columbia
Tissue Perfusion, Deliberate Hypotension
Effects of Nitroglycerin Versus Labetalol on Tissue Perfusion During Deliberate Hypotension
Deliberate hypotension is used to provide bloodless field during endoscopic sinus surgery; however, hypotension might impair perfusion of vital organs.
- Conditions
- Tissue Perfusion, Deliberate Hypotension, Sinus Endoscopic Surgery
- Trial name
- NCT03809065
- Testing
- Nitroglycerin, Labetalol
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Hypotension During Surgery, NGAL
Controlled Hypotension and Renal Injury During Septoplasty
This prospective randomized single-blind study investigated the effects of two different mean arterial pressure (MAP) targets during controlled hypotension on renal injury in patients undergoing septoplasty.
- Conditions
- Hypotension During Surgery, NGAL, Kidney Injury
- Trial name
- NCT07662577
- Testing
- Controlled Hypotension (MAP 50-57 mmHg), Controlled Hypotension (MAP 58-65 mmHg)
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Hypotension During Surgery, Cesarean Birth
OB VEGA-Phenylephrine vs Norepinephrine Outcomes
OB VEGA-Phenylephrine vs Norepinephrine Outcomes evaluation
- Trial name
- NCT07900919
- Testing
- Phenylephrine, Norepinephrine
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- Wake Forest University Health Sciences
Anesthesia, Surgery With General Anesthesia
The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac Surgery
Low blood pressure, also known as hypotension, is very common during major surgery under general anesthesia. Prolonged or severe hypotension can lead to complications such as kidney injury after surgery that slow down patient…
- Conditions
- Anesthesia, Surgery With General Anesthesia, Noncardiac Surgery, Hypotension During Surgery
- Trial name
- VEGA-2 (NCT06802224)
- Testing
- Norepinephrine, Phenylephrine
- Where
- 10 sites in United States, Canada
- Volunteers
- 18,000 people
- Sponsor
- University of California, San Francisco
Shoulder Surgery, Beach Chair Position
Effect of the Side of Interscalene Block on Bradycardia and Hypotension in Beach Chair Position
The Left interscalene block has a different effect on heart's autonomic nervous system, compared to Right interscalene block. This effect is evident on the occurrence of bradycardia and hypotension during shoulder surgery in the…
- Conditions
- Shoulder Surgery, Beach Chair Position, Interscalene Block, Hypotension
- Trial name
- NCT01755780
- Testing
- Left interscalene block, Right interscalene block
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- Larissa University Hospital
Intraocular Pressure Low
Effect of Hyaluronidase on Intraocular Pressure
The aim of this study is to evaluate effect of retrobulbar local anaesthesia after addition of hyaluronidase on IOP during cataract surgery
- Trial name
- NCT03266406
- Testing
- Hyaluronidase
- Volunteers
- 50 people
- Sponsor
- Assiut University
Myocardial Injury After Non-cardiac Surgery, Hypotension During Surgery
The Effects of General Versus Spinal Anesthesia on Postoperative Myocardial Injury
In this prospective, randomized, single-blind study, we aim to compare the effects of general anesthesia and spinal anesthesia on postoperative myocardial injury in elderly patients undergoing hip surgery.
- Conditions
- Myocardial Injury After Non-cardiac Surgery, Hypotension During Surgery, Anesthesia, General, Anesthesia, Spinal
- Trial name
- NCT06343259
- Testing
- General Anesthesia, Spinal Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Magnesium Sulfate, Remifentanil
Anesthesia Techniques, Neuroprotection and Surgical Field in FESS Under Controlled Hypotension
This prospective, randomized controlled trial investigates the effect of four different anesthetic maintenance techniques on surgical field conditions, hemodynamic stability, and neuroprotection during functional endoscopic sinus…
- Conditions
- Magnesium Sulfate, Remifentanil, S 100beta, S100 Beta Protein, Human
- Trial name
- NCT07181564
- Testing
- Propofol / Remifentanil, Ketamine + Magnesium sulfate (drug combination), Sevoflurane and Remifentanil
- Where
- Greece
- Volunteers
- 150 people
- Sponsor
- University General Hospital of Patras
Rotator Cuff Tear Arthropathy
Vasopressin to Prevent Hypotension During Beach Chair Surgery
Patients undergoing surgery in beach chair position (BCP) are at risk for cerebral ischaemia. The impacts of arginine vasopressin (AVP) on haemodynamics and cerebral oxygenation are evaluated during surgery in BCP.
- Trial name
- NCT01687894
- Testing
- Vasopressins, propofol, sevoflurane
- Where
- South Korea
- Volunteers
- 74 people
- Sponsor
- Chonnam National University Hospital
Endoscopic Sinus Surgery
Propofol and Magnesium Sulfate Intravenous Infusion During Endoscopic Sinus Surgery
Endoscopic Sinus surgery usually associated by bleeding, despite using of local vasopressor injection, head up position- controlled hypotension is generally used for control of this purpose.
- Trial name
- NCT04078659
- Testing
- Propofol infusion, Magnesium Sulfate infusion, Lidocaine
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Hemorrhage
Controlled Hypotension During Functional Endoscopic Sinus Surgery
It is very important to decrease the bleeding during functional endoscopic sinus surgery (FESS) in order to increase the visibility of the surgical site.
- Trial name
- NCT01956981
- Testing
- Magnesium Sulfate, Dexmedetomidine
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Hypotension, Poor Peripheral Perfusion
Effect of Vasopressin on Tissue Oxygen Saturation in Cardiac Surgery Patients During Cardiopulmonary Bypass
The objective of this research is to compare the effect of a low dose Vasopressin infusion or placebo during cardiopulmonary bypass on vasopressor requirements, hemodynamics and tissue oxygen saturation and its recovery using…
- Trial name
- NCT01532505
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Mohamed Ismail
TURP(Transurethral Resection of Prostate), Spinal Anesthesia
Modified Saddle Block vs Spinal Anesthesia for TURP
After obtaining informed consent, eligible patients will be enrolled in the study. Standard monitoring will be applied in the operating room and baseline blood pressure and heart rate will be recorded.
- Conditions
- TURP(Transurethral Resection of Prostate), Spinal Anesthesia, Saddle Block Anesthesia, Hypotension During Surgery
- Trial name
- NCT07841184
- Testing
- Saddle block, Spinal Anesthesia (bupivacaine)
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Etomidate, Hypotension
The Safety of Etomidate - Propofol Mixture vs Propofol in Total Intravenous Anesthesia During Abdominal Surgery
The purpose of this study is to access the safety of etomidate - propofol mixture vs propofol in total intravenous anesthesia during abdominal surgery.
- Trial name
- NCT05810363
- Testing
- Etomidate - propofol mixture, Propofol
- Where
- China
- Volunteers
- 468 people, healthy volunteers welcome
- Sponsor
- Ailin Luo
Hypotension on Induction
CirQPOD Shoulder Study
Intrathoracic pressure regulation (IPR) therapy, delivered by impedance threshold devices (ITDs) or intrathoracic pressure regulators (ITPRs), increases venous return, preload, cardiac output, blood pressure, and cerebral…
- Trial name
- NCT04299776
- Testing
- CirQPOD, Standard airway management
- Where
- United States
- Sponsor
- Zoll Medical Corporation
Hypotension During Surgery, Kidney Transplant; Complications
Hypotension Prediction With HPI Algorithm During Decessed-donor Kidney Transplant (HPI2022)
HPI monitoring and the adoption of therapeutic interventions before hypotension occurs should be ensure a shorter time of intra-operative hypotension (MAP < 65 mmHg) during deceased-donor kidney transplant surgery.
- Trial name
- HPI2022 (NCT05394896)
- Testing
- ACUMEN (Edwards Lifesciences, Irvine, USA), Invasive Blood Pressure
- Where
- Italy
- Volunteers
- 46 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna