Clinical trials: Hypotensive Anesthesia
Trehalase Levels, Acute Kidney Injury
Early Diagnosis of Acute Renal Failure by Urine Trehalase Levels.
We think that in surgical patients requiring hypotensive anesthesia, acute kidney injury, which may occur due to intraoperative renal hypoperfusion, can be diagnosed early by evaluating the urine trehalase value using the ELISA…
- Trial name
- NCT06505655
- Testing
- trehalase levels
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istinye University
Endoscopic Sinus Surgery
The Effect of Dexmedetomidine, Melatonin and Pregabalin
Various drugs have been used for the purpose: nitroglycerine, sodium nitroprusside, propofol, beta blockers, calcium channel blockers, higher concentrations of inhalational anesthetics etc.
- Trial name
- NCT05829148
- Testing
- Dexmedetomidine, Melatonin, Pregabalin
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Egymedicalpedia
Hypotension, Pregnancy
Intravenous Ondansetron to Attenuate the Hypotensive, Bradycardic Response to Spinal Anesthesia in Healthy Parturients
The investigators hypothesize that given prophylactically, intravenous ondansetron will attenuate the drop in blood pressure and heart rate frequently seen after spinal anesthesia.
- Trial name
- NCT01414777
- Testing
- ondansetron
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Virginia
Blood Pressure, Hypotension
Hypotensive Effect of Anaesthesia With TCI
Hypotension will often complicate induction of anaesthesia. The investigators want to test the hypothesis that Target Controlled Infusion, as opposed to Velocity Controlled Infusion, leads to less degree of hypotension.
- Trial name
- HEAT (NCT02733406)
- Testing
- Target Controlled Infusion, Velocity Controlled Infusion
- Where
- Sweden
- Volunteers
- 76 people
- Sponsor
- Umeå University
Functional Endoscopic Sinus Surgery
Comparison Between Pregabalin and Magnesium Sulfate in Hypotensive Anaesthesia
Comparison between pregabalin and magnesium sulfate in hypotensive anaethesia
- Trial name
- NCT05442931
- Testing
- Pregabalin 150mg, Magnesium Sulfate, Nitroglycerin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Minia University
Spine Surgery
Pregabalin Effects on Hypotensive Anesthesia During Spine Surgery.
Elective lumbar spine surgical procedures are commonly performed under controlled hypotension during general anesthesia. That is beneficial to limit the intraoperative blood loss and transfusions and improves surgical field.
- Trial name
- NCT03301025
- Testing
- Pregabalin
- Where
- 2 sites in Egypt
- Volunteers
- 106 people
- Sponsor
- Mansoura University
Hypotensive Anesthesia
Comparison Between Two Drugs (Propofol and Nitroglycerin as a Hypotensive Agents During Endoscopic Sinus Surgery
Background and Objectives: FESS is a common minimally invasive surgery that requires a clear field to be performed well. Hypotensive anesthesia is one of the most common maneuvers performed to help in keeping the field clear.
- Trial name
- prop (NCT04220281)
- Testing
- Propofol, Nitroglycerin
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Anesthesia, Hypotension
Anesthetic Advantages of Dexmedetomidine for Hypotensive Anesthesia
The aim of this study was to evaluate the positive anesthetic properties such as reduce intraoperative analgesic requirement, time to extubation and recovery, and early postoperative pain of dexmedetomidine used as a hypotensive…
- Trial name
- NCT02083055
- Testing
- Dexmedetomidine, Nitroglycerin
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Controlled Hypotension for Nasal Surgeries
Effect of Hypotensive Anesthesia on the Perfusion Index
Controlled hypotension has been used as a mean of reducing intraoperative blood loss and better visualization of the surgical field in nasal surgeries.
- Trial name
- NCT03059316
- Testing
- Massimo device, Nitroglycerin drug, Labetalol
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hypoxemia During Surgery, Hypoxia
Evaluation of the Effect of Sevoflurane and Propofol Hypotensive Anesthesia on Blood Antioxidant Levels and HIF 1 Levels
The aim of this study to evaluate the patients who underwent controlled hypotensive anesthesia under standardized depth of anesthesia with total intravenous anesthesia or inhalation anesthesia; preoperative and 30. ,60. ,120.
- Trial name
- NCT04246567
- Testing
- Mean Blood Pressure (MBP), Add to 0.5 mcg / kg fentanyl.
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bezmialem Vakif University
Nasal Septum Deviation
Effects of Hypotensive Anesthesia on Thiol Disulphide Balance
Oxidative stress at the cellular level and the effects of the antioxidant system on the anesthetic drugs make the anesthesia method more important.
- Trial name
- NCT03501563
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Monitoring During Deliberate Hypotensive Anesthesia
Peripheral Perfusion Index (PPI) as Monitor During Deliberate Hypotensive Anesthesia
Hypotensive anesthesia is effective in reducing the intraoperative blood loss. The risk of hypoperfusion of vital organs continues to be a concern. An adequate monitoring of tissue perfusion and oxygenation is crucial issue.
- Trial name
- PPI (NCT03007355)
- Testing
- peripheral perfusion index measurement
- Volunteers
- 50 people
- Sponsor
- Cairo University
Hypotension Drug-Induced
Is Labetalol More Effective Than Metoprolol for Controlled Hypotensive Anesthesia During Endoscopic Nasal Surgeries?
Background: Mucosal bleeding is the most frequent complication with endoscopic nasal surgeries, as it interferes with the optimal visualization of the intranasal anatomy, leading to increased complications, operation duration…
- Trial name
- NCT05368376
- Testing
- Labetalol Hydrochloride Oral Tablet, Metoprolol Tartrate Oral Tablet
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Damanhour Teaching Hospital
Supine Hypotensive Syndrome, Cesarean Section Complications
Arm and Ankle Blood Pressure Cuffs During C-Section
This is a single center prospective self-control study to validate the effectiveness of left uterine displacement after subarachnoid block (SAB) with simultaneous measurements of blood pressure (BP) on the arm and left ankle…
- Conditions
- Supine Hypotensive Syndrome, Cesarean Section Complications, Anesthesia Complication
- Trial name
- NCT04934995
- Testing
- Blood Pressure Cuff
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ohio State University
Hypoxemia During Surgery, Hypoxia, Brain
Effect of Hypotensive Anesthesia on Cerebral Perfusion and Blood Antioxidant Levels and HIF 1a
The aim of this study to evaluate the patients who underwent controlled hypotensive anesthesia under standardized depth of anesthesia; preoperative and postoperative blood HIF 1a, TAS, TOS measurement and cerebral perfusion…
- Trial name
- NCT04174417
- Testing
- systolic blood pressure (SBP), mean blood pressure (MBP)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bezmialem Vakif University
Anaesthetic Drugs, Hypotensive Drugs, Perioperative Analgesia
Ultrasound Guided Erector Spinae Plane Block Combined With General Anaesthesia Versus Conventional General Anaesthesia in Lumbar Spine Surgery
Ultrasound guided erector spinae plain block combined with general anaesthesia versus conventional general anaesthesia in lumbar spine surgery, it's hypothesized that combined regional anaesthesia with general anaesthesia in…
- Trial name
- US ESP block (NCT04302129)
- Testing
- Erector spinae plane block, Multimodal analgesia
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mohamed Elsayed
Patient With Nasolacrimal Duct Obstruction, External Dacryocystorhinostomy Operation
Effect of Local Anesthesia Versus Induced Hypotensive Anesthesia on Quality of External Dacryocystorhinostomy Operation
Bleeding is one of the important complications during Dacryocystorhinostomy, which dissatisfy ophthalmic surgeon, reduces surgical field visualization, and increases the duration of surgery Thus, the management of this…
- Trial name
- NCT05241054
- Testing
- Bupivacaine, Nitroglycerine, Propofol
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Mansoura University
Hypotensive Anesthesia
Regional Block of the Nose for Hypotensive Anaesthesia in Septo-rhinoplasty
Septorhinoplasty is a cosmetic surgery that many people are choosing to undergo. It can be done under general anesthesia, twilight anesthesia or regional anesthesia.
- Trial name
- NCT03774693
- Testing
- General anesthesia with fentanyl boluses, Regional block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Pain After Surgery
Effect of the Superficial Cervical Plexus Block in the Hypotensive Anesthesia of Ear Surgery.
We aimed to evaluate the analgesic effect of ultrasound guided Superficial cervical plexux block in tympanomastoid ear surgeries by comparing it with conventional general anaesthesia using systemic analgesic through observation…
- Trial name
- NCT07241364
- Testing
- nerve block with bupivacaine 0.25%
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Ain Shams University
Blood Volume Analysis
Blood Volume Analysis of Total Hip Arthroplasty Patients Under Hypotensive Anesthesia
Hypotensive Anesthesia is a type of regional anesthesia performed routinely at our hospital. This type of anesthesia reduces the average arterial pressure. Benefits include reduced bleeding and lower risk of blood clots.
- Trial name
- NCT02148809
- Testing
- 1mL of I-131 Human Serum Albumin is injected prior to the measurements
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Hospital for Special Surgery, New York