Clinical trials: Hypothyroidism
Obesity and Obesity-related Medical Conditions
Outcomes Of Laparoscopic Sleeve Gastrectomy In Patients With Hypothyroidism And Depression
Sleeve gastrectomy (SG) continues to be one of the most popular bariatric procedures all over the world. It has been established that obesity is a predisposing factor for several comorbidities, including life-threatening…
- Trial name
- NCT06859320
- Testing
- laparoscopic sleeve gastrectomy
- Where
- 2 sites in Egypt
- Volunteers
- 24 people
- Sponsor
- Zagazig University
Hypothyroidism
Effects of L-carnitine on Hypothyroidism
L-carnitine and thyroid hormone tended to antagonize reciprocally in human body. Urinary excretion of L-carnitine decreased in hypothyroid patients, and levothyroxine supplementation increased excretion of L-carnitine.
- Trial name
- NCT01769157
- Testing
- L-carnitine
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Korea University Anam Hospital
Aging, Primary Hypothyroidism
Evaluation of Evening Versus Morning Levothyroxine Intake in Elderly
A study designed to compare evening versus morning levothyroxine intake in the elderly.
- Conditions
- Aging, Primary Hypothyroidism, Interaction Drug Food
- Trial name
- MONIALE (NCT03614988)
- Testing
- Evening Levothyroxine Administration, Morning Levothyroxine Administration
- Where
- Brazil
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Congenital Hypothyroidism
Comparison of Levothyroxine Formulations in the Treatment of Congenital Hypothyroidism
Observational, retrospective, prospective, pharmacological, single-centre, non-profit study. The aim is to evaluate, in newborns diagnosed with Congenital Hypothyroidism, the medium- and long-term efficacy and safety of the new…
- Trial name
- NCT06724224
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Heart Failure, Subclinical Hypothyroidism
Thyroid Hormone Replacement for Subclinical Hypothyroidism and Chronic Heart Failure (ThyroHeart-CHF)
Based on accumulating evidence showing that hypothyroid status is associated with poor prognosis among heart failure (HF) patients, the study is designed to evaluate whether replacement treatment with levothyroxine could have…
- Trial name
- NCT03096613
- Testing
- Levothyroxine
- Where
- China
- Volunteers
- 124 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Breast Neoplasms, Hypothyroidism
A Prospective Study of Hypothyroidism After Radiotherapy for Breast Cancer
This study is to prospectively investigate the incidence of hypothyroidism after postoperative radiotherapy and identify risk factors for development of hypothyroidism.
- Conditions
- Breast Neoplasms, Hypothyroidism, Radiation Toxicity
- Trial name
- NCT04528225
- Where
- China
- Volunteers
- 729 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Intracerebral Hemorrhage, Low T3 Syndrome
Efficacy of Thyroid Hormone Replacement for Secondary Hypothyroidism Following Intracerebral Hemorrhage
Low levels of serum triiodothyronine (T3) thyroid hormones (T4) are a strong predictor of mortality and poor prognosis in critical care patients. Few reports, however, have focused on neurocritical patients.
- Conditions
- Intracerebral Hemorrhage, Low T3 Syndrome, Neurocritical Care, Hormone Replacement Therapy
- Trial name
- NCT06353555
- Testing
- Euthyrox
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking Union Medical College Hospital
Hypothyroidism, Global Developmental Delay
Register for Patients With Thyroid Hormone Resistance.
Thyroid hormones (TH) play a pivotal role in the development and function of the mammalian brain. Patients with impaired thyroid hormone transport into the brain tissue or in the case of defective local thyroid hormone receptor…
- Conditions
- Hypothyroidism, Global Developmental Delay, Intellectual Disability, Dystonia
- Trial name
- DEEPTYPE (NCT06566066)
- Testing
- no intervention
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Charite University, Berlin, Germany
Pregnancy Related, Hypothyroidism
TSHβX1 and D2 THR92ALA in Pregnancy
Thyroid diseases are pathologies that frequently affect pregnant women causing serious complications. This current research aims to find out whether the expression of TSHβX1 splice variant and D2 Thr92Ala polymorphism in the DIO2…
- Conditions
- Pregnancy Related, Hypothyroidism, Hyperthyroidism
- Trial name
- NCT03612908
- Where
- Mexico
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Materno-Perinatal Hospital of the State of Mexico
Thyroid Dysfunction, Hypothyroidism
Fetal and Neonatal Thyroid in Pregnancies With Severe Acute Respiratory Syndrome Coronavirus 2 ( SARS- COV2 ) COVID-19
The thyroid gland has been shown to be a common target for COVID 19 virus. Babies born to mothers positive for COVID 19 infections were noticed to have elevated thyroid stimulating hormone ( TSH ) levels on screening.
- Conditions
- Thyroid Dysfunction, Hypothyroidism, Hyperthyroidism
- Trial name
- COVID-19 (NCT05385029)
- Testing
- Thyroxine
- Where
- Saudi Arabia
- Volunteers
- 95 people
- Sponsor
- OMER B ABDELBASIT
Breast Cancer, Fatigue
Thyroid Dysfunction in Women With Newly Diagnosed Breast Cancer Compared to Healthy Volunteers
RATIONALE: Learning about thyroid dysfunction in patients with breast cancer may help plan treatment and may help patients live more comfortably.
- Conditions
- Breast Cancer, Fatigue, Hypothyroidism
- Trial name
- NCT00336102
- Testing
- physiologic testing, fatigue assessment and management, management of therapy complications
- Where
- 41 sites in United States
- Volunteers
- 541 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Hypothyroidism
Vitamin E Add-On Therapy, Thyroid Function & Oxidative Stress in Levothyroxine-Treated Hypothyroidism
The aim of this study is to learn if vitamin E supplementation as an adjunct to levothyroxine therapy help to reduce oxidative stress, improve antioxidant defence mechanisms, and favourably influence thyroid hormone status…
- Trial name
- NCT07781514
- Testing
- vitamin E
- Where
- Bangladesh
- Volunteers
- 74 people
- Sponsor
- Bangladesh Medical University
Hypothyroidism
The Relationship Between Serum rT3 Concentrations, T3/T4 Ratio, and Symptoms/Quality of Life in Treated Hypothyroid Patients
The aim of this study is to evaluate the relationship between serum rT3 (serum reverse triiodothyronine) concentrations, T3/T4 (triiodothyronine/thyroxine) ratio, and persistent symptoms /quality of life in treated hypothyroid…
- Trial name
- NCT05015725
- Testing
- Quality of life assessment, biochemical measures
- Where
- Hungary
- Volunteers
- 262 people
- Sponsor
- Semmelweis University
Thyroid Cancer, Postsurgical Hypothyroidism
Levothyroxine Replacement With Liquid Gel Capsules vs Tablets Post-thyroidectomy
In some patients, levothyroxine liquid gel capsules may demonstrate superior absorption than the tablet option. Impaired absorption of thyroid hormone directly correlates to higher and more unpredictable TSH (thyroid stimulating…
- Trial name
- NCT02946918
- Testing
- Levothyroxine
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Texas Southwestern Medical Center