Clinical trials: Hypothyroidism
Hypothyroidism; Surgery, Head and Neck Cancer
Wound Complications in Head and Neck Surgery
This is a prospective observational study evaluating wound complications following head and neck surgery. Patients undergoing major head and neck surgery will be included in the study.
- Conditions
- Hypothyroidism; Surgery, Head and Neck Cancer, Wound Heal, Laryngeal Cancer
- Trial name
- NCT03134976
- Testing
- Levothyroxine
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Michigan
Cardiovascular Diseases, Coronary Disease
Immunogenetic Factors of Coronary Heart Disease
To assess the association of immunogenetic factors with onset of coronary heart disease and the interrelationship of these factors with standard coronary heart disease risk factors.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Hypertension
- Trial name
- NCT00005184
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Thyroid, Thyroid Dysfunction
Upper Limit for TSH of First and Second Trimester Pregnancy in Turkey
Physiological changes necessitate the use of pregnancy-specific reference ranges for TSH and FT4 to diagnose thyroid dysfunction during pregnancy.
- Conditions
- Thyroid, Thyroid Dysfunction, Hypothyroidism, Pregnancy Early
- Trial name
- NCT03754621
- Testing
- Serum thyroid functions tests
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Bartin State Hospital
Subclinical Hypothyroidism
Subclinical Hypothyroidism and Mind in the Elderly
Some recommendations of expert consensus on subclinical hypothyroidism (SH) are controversial in those areas with not enough information to reach a conclusion, such as not recommending treatment with thyrotrophic hormone of 4-10…
- Trial name
- NCT00921050
- Testing
- levothyroxine sodium
- Where
- 2 sites in Mexico
- Volunteers
- 70 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Polycystic Ovary Syndrome, Hypothalamic-Pituitary-Ovarian Axis Dysfunction (Disorder)
Subclinical Hypothyroidism and Normogonadotropic Anovulation
Thyroid hormones (TH) can modify the functioning of the hypothalamic-pituitary-ovarian axis, affecting the functions of granulosa cells and the development and apoptosis of preantral follicles.
- Trial name
- NCT05782725
- Testing
- Comparison of laboratory test results in women in the 4 study arms
- Where
- Poland
- Volunteers
- 300 people
- Sponsor
- Jagiellonian University
Hypothyroidism
Insulin Sensitivity and Metabolism Before and After Treatment in Patients With Hypothyroidism
The aim of this study is to further characterize the treatment related changes in insulin sensitivity, substrate metabolism and intra hepatic- and intramyocellular lipid content in patients with hypothyroidism
- Trial name
- NCT00770016
- Testing
- Levothyroxin
- Where
- Denmark
- Sponsor
- University of Aarhus
Hypothyroidism
Early Detection of Endolymphatic Hydrops in Hypothyroid Patients
Early detection of endolymphatic hydrops in hypothyroid patients Study outcome of medical treatment for hypothyroid patients
- Trial name
- NCT05334771
- Testing
- Dual band pure tune audiometer
- Volunteers
- 50 people
- Sponsor
- Assiut University
Hypothyroidism
Effect of Medication Adherence-Based Digital Intervention on Fatigue Severity, Weight, and Thyroid Hormone Regulation
1. To evaluate the effect of a medication adherence-based digital intervention on fatigue severity in patients with hypothyroidism. 2.
- Trial name
- NCT07636681
- Testing
- medication adherence based digital intervention
- Where
- Iraq
- Volunteers
- 80 people
- Sponsor
- University of Baghdad
Metabolic Dysfunction-Associated Steatotic Liver Disease, Non-Alcoholic Fatty Liver Disease
Impact of Overt and Subclinical Hypothyroidism on Liver Fibrosis in Patients With MASLD
Metabolic dysfunction-associated steatotic liver disease (MASLD), previously known as non-alcoholic fatty liver disease (NAFLD), is one of the most common chronic liver conditions globally.
- Conditions
- Metabolic Dysfunction-Associated Steatotic Liver Disease, Non-Alcoholic Fatty Liver Disease, Hypothyroidism, Liver Fibrosis
- Trial name
- NCT07827430
- Volunteers
- 120 people
- Sponsor
- Assiut University
Nodule Solitary Thyroid, Toxic Multinodular Goiter
An Assessment of the Occurrence of Hypothyroidism in Patients Treated With RAI for Hyperthyroidism.
Low RAIU in patients with hyperthyroidism represents a common obstacle in the treatment with RAI. Therefore, a higher dose of RAI must be administered to cure hyperthyroidism in these patients.
- Conditions
- Nodule Solitary Thyroid, Toxic Multinodular Goiter, Radioactive Iodine-Induced Hypothyroidism
- Trial name
- NCT04663451
- Testing
- radioacive iodine therapy
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Universitair Ziekenhuis Brussel
Hepatic Steato-Fibrosis, Non-Alcoholic Fatty Liver Disease
MASLD in Primary Hypothyroidism and Efficacy of Dapaglifozin
Non-alcoholic fatty liver disease (NAFLD) is a global epidemic with a prevalence of 25-40%.Primary Hypothyroidism is one of Endocrinopathies who are at risk of developing NAFLD/NASH and estimated prevalence of Primary…
- Trial name
- SHIELD (NCT06373523)
- Testing
- Dapagliflozin 10mg Tab, Levothyroxine Replacement daily
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Attention Deficit Disorder With Hyperactivity, Asthma
Study of an Intervention to Improve Problem List Accuracy and Use
The aim of this study is to identify patients with problem list gaps and intervene to correct these gaps by creating clinical decision support interventions that alert providers to likely problem list gaps and offer clinicians…
- Conditions
- Attention Deficit Disorder With Hyperactivity, Asthma, COPD, Breast Cancer
- Trial name
- MAPLE (NCT01105923)
- Testing
- MAPLE
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Brigham and Women's Hospital
Subclinical hypothyroïdism
Assessment of Bone Mineral Density in Patients With Subclinical Hypothyroidism
This study aims to recognize the effects of subclinical hypothyroidism on bone mineral density, Not many studies were done on this subject
- Trial name
- ABMDPSH (NCT04270110)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Iodine Deficiency, Subclinical Hypothyroidism
Iodine Supplementation in Obesity
The study hypothesis is that iodine supplementation will lower serum TSH and leptin concentrations and thereby improve the lipid and glucose profile.
- Trial name
- NCT01985204
- Testing
- Iodine tablet
- Where
- 2 sites in Morocco
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Subclinical Hypothyroidism
Thyroid Hormone Replacement for Subclinical Hypothyroidism
Subclinical hypothyroidism (SCH) is a common condition among older men and women. Although by definition SCH comprises biochemically mild thyroid hormone deficiency without overt symptoms, it is a possible contributor to multiple…
- Trial name
- TRUST (NCT01660126)
- Testing
- Levothyroxine
- Where
- United Kingdom
- Volunteers
- 737 people
- Sponsor
- NHS Greater Glasgow and Clyde
Subclinical Hypothyroidism, Infertility
Levothyroxine Treatment and IVF Outcomes in Women With Subclinical Hypothyroidism: A Target Trial Emulation
Subclinical hypothyroidism (SCH) is defined by elevated thyroid-stimulating hormone (TSH) with normal free thyroxine (fT4) levels.
- Conditions
- Subclinical Hypothyroidism, Infertility, Assisted Reproductive Technology, In Vitro Fertilization (IVF)
- Trial name
- LESI (NCT07257250)
- Where
- 2 sites in Vietnam
- Volunteers
- 900 people
- Sponsor
- Mỹ Đức Hospital
Hypothyroidism
The Yield of Postnatal Thyroid Function Test in the Well Baby Nursery
Thyroid function test are performed in the well baby nursery to newborn infants of mothers with hypothyroidism, or as part of neonatal jaundice investigation.
- Trial name
- NCT05033496
- Testing
- Thyroid function test
- Where
- Israel
- Volunteers
- 40,601 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Hypothyroidism
Observational Study on Hypothyroidism in Young Children Following Iodine Contrast Exposure
To investigate the incidence of detected hypothyroidism after iodinated contrast exposure in pediatric patients from birth to 3 years of age (inclusive) in a routine clinical practice setting.
- Trial name
- NCT02766283
- Testing
- iodinated contrast agents
- Where
- Israel
- Volunteers
- 843 people
- Sponsor
- Bayer
Hyperthyroidism, Hypothyroidism
Natural History of Thyroid Function Disorders
Participants in this study will be patients diagnosed with or suspected to have a thyroid function disorder. These conditions may include: hypothyroidism, hyperthyroidism, thyroid hormone resistance, Graves' Dermopathy, and…
- Conditions
- Hyperthyroidism, Hypothyroidism, Grave's Disease
- Trial name
- NCT00001159
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Thyroid Volume, Thyroid Ultrasound
Ultrasound Measurement of Thyroid Volume in Term Newborns
First, to date, no data are available on the thyroid volume of full-term newborns in Italy, making it essential to conduct studies to establish reference values for normality.
- Conditions
- Thyroid Volume, Thyroid Ultrasound, Congenital Hypothyroidism, Healthy Newborns
- Trial name
- NEOTIR (NCT07579988)
- Testing
- Thyroid ultrasound
- Where
- Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- IRCCS Ospedale San Raffaele