Clinical trials: Hypoxemia
Severe Acute Respiratory Syndrome Coronavirus 2, COVID-19
CORONA (COvid pRONe hypoxemiA): Prone Positioning for Hypoxemic COVID-19 Patients With Do-not-intubate Goals
The purpose of this trial is to determine whether Prone Positioning (PP) improves outcomes for non-intubated hospitalized patients with hypoxemic respiratory failure due to COVID-19, who are not candidates for mechanical…
- Conditions
- Severe Acute Respiratory Syndrome Coronavirus 2, COVID-19, Acute Respiratory Distress Syndrome, ARDS
- Trial name
- CORONA (NCT04402879)
- Testing
- Prone Positioning (PP)
- Where
- 4 sites in Canada
- Volunteers
- 596 people
- Sponsor
- University of Calgary
Atelectasis, Pulmonary Infection
Bi-PAP vs Sham Bi-PAP on Pulmonary Function in Morbidly Obese Patients After Bariatric Surgery
The effect of biphasic positive airway pressure (Bi-PAP) at individualized pressures on the postoperative pulmonary recovery of morbidly obese patients (MOP) undergoing open bariatric surgery (OBS) and possible placebo…
- Conditions
- Atelectasis, Pulmonary Infection, Chronic Obstructive Pulmonary Disease (COPD), Pulmonary Disease
- Trial name
- NCT03438383
- Testing
- Bi-PAP
- Volunteers
- 48 people
- Sponsor
- Evangelismos Hospital
Hypoxemia
Effects of Acute Intermittent Hypoxia on Brain Function Imaging and Systemic Inflammation
Effects of acute intermittent hypoxia on brain function imaging and systemic inflammation Patients with obstructive sleep apnea (OSAS) may have neurological cognitive impairment. The reason is not clear.
- Trial name
- NCT03453697
- Testing
- acute intermittent hypoxia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Pneumonia Childhood
A Feasibility Study Evaluating a Novel Mask (Nasal Reservoir Cannula)
This study evaluates the addition of a novel mask (nasal reservoir cannula) to a standard nasal cannula during supplemental oxygenation for the treatment of hospitalized pediatric patients with hypoxemia due to severe pneumonia.
- Trial name
- NCT03929484
- Testing
- Nasal reservoir cannula
- Where
- Uganda
- Volunteers
- 8 people
- Sponsor
- University of California, San Francisco
COVID-19 Pneumonia, Non-invasive Ventilation
The Difference Between Non-invasive High-frequency Oscillatory Ventilation and Non-invasive Continuous Airway Pressure Ventilation in COVID-19 With Acute Hypoxemia
High frequency oscillatory ventilation (HFOV), as an ideal lung protection ventilation method, has been gradually applied to neonatal intensive care treatment, and is currently recommended as a rescue method for neonatal acute…
- Trial name
- NCT05706467
- Testing
- Non-invasive high-frequency oscillatory ventilation, Non-invasive continuous positive airway pressure ventilation
- Volunteers
- 20 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Hypoxemia, Extubation
Postoperative Extubation in Hypoxemic Patients
The objective of this clinical trial is to assess whether early extubation of patients with hypoxemia during the spontaneous breathing trial (SBT) shortens the duration of ventilatory support.
- Conditions
- Hypoxemia, Extubation, Postoperative Respiratory Complication
- Trial name
- EPHYRE (NCT06688487)
- Testing
- early extubation of hypoxemic patients
- Where
- 12 sites in France
- Volunteers
- 152 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Hypoxemia
Regimen of Alfentanil in Propofol Sedative Fibro-bronchoscopy
Alfentanil (Alf) is used in combination with Propofol (Pro) in fiber-bronchoscopy and in many other conscious sedation procedures.
- Trial name
- NCT01470170
- Testing
- Alfentanil, Normal saline, Targeted controlled infusion
- Where
- Taiwan
- Volunteers
- 173 people
- Sponsor
- Chang Gung Memorial Hospital
Hypoxemia, Pulse Oximetry
Pulse Oximetry Errors in Hospitalized Patients Across Varying Skin Pigmentation
This is a prospective observational study designed to quantify and understand errors in pulse oximetry in hospitalized patients in relation to their skin pigmentation.
- Conditions
- Hypoxemia, Pulse Oximetry, Skin Pigment
- Trial name
- EquiOx (NCT05554510)
- Testing
- Observational
- Where
- United States
- Volunteers
- 757 people
- Sponsor
- University of California, San Francisco