Clinical trials: Hypoxemia, open to volunteers
Apnea of Prematurity, Intermittent Hypoxemia
Strap To Reduce Apnea in Preterm Infants: A Randomized Crossover Trial
The goal of this clinical trial is to learn if a chin strap helps reduce low oxygen episodes in premature babies receiving CPAP or NIPPV (breathing support through the nose).
- Conditions
- Apnea of Prematurity, Intermittent Hypoxemia, Bronchopulmonary Dysplasia of Newborn
- Trial name
- STRAP (NCT07895654)
- Testing
- Chinstrap
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Alabama at Birmingham
Postoperative Hypoxemia
Transoral Nasal Cannula Oxygen Therapy for Mouth-Breathing Patients in the Postanesthesia Care Unit
Postoperative hypoxemia is a common complication in the postanesthesia care unit (PACU). Patients who breathe through the mouth after tracheal extubation may receive limited benefit from standard nasal cannula oxygen therapy…
- Trial name
- NCT07841223
- Testing
- Transoral nasal cannula oxygen delivery
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Hypoxemia, Skin Pigment
Skin Pigment/Pulse Oximeter in Congenital Heart Disease (CHD)
Recent retrospective studies have demonstrated differences between pulse oximeter values (SpO2) and measured arterial oxygen saturation (SaO2) in patients identifying as Black or Hispanic.
- Conditions
- Hypoxemia, Skin Pigment, Congenital Heart Disease
- Trial name
- NCT06575270
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hypoxemia
Transcutaneous Auricular Vagus Nerve Stimulation for Reducing Postoperative Hypoxemia
Hypoxemia is a common complication in the post-anesthesia care unit (PACU) and represents one of the most meaningful factors associated with poor patient prognosis. Obese patients have a relatively higher incidence of hypoxemia.
- Trial name
- NCT07827131
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulator
- Volunteers
- 80 people
- Sponsor
- Affiliated Hospital of Nantong University
Acute Respiratory Distress Syndrome (ARDS), Pneumonia
Medical Device Clinical Trial Without CE Marking to Evidence Safety and Performance of the INBENTUS VERSATILE Ventilator in Patients Requiring Assisted/Controlled Mechanical Ventilation and Weaning.
Pre-market clinical trial on 81 aldults participants to evidence safety and performance of the non-CE-marked medical device INBENTUS VERSATILE ventilator.
- Conditions
- Acute Respiratory Distress Syndrome (ARDS), Pneumonia, COPD (Chronic Obstructive Pulmonary Disease), Postoperative Respiratory Distress
- Trial name
- NCT07432191
- Testing
- INBENTUS VERSATILE
- Where
- Spain
- Volunteers
- 81 people
- Sponsor
- Iconic Solutions By Murcia SL
Interstitial Lung Disease, Chronic Obstructive Pulmonary Disease
Titrated Ambulatory Oxygen in Fibrotic ILD and COPD With Isolated Exertional Hypoxemia
Fibrotic forms of interstitial lung disease (ILD) and chronic obstructive pulmonary disease (COPD) are chronic lung disease which often affect how well oxygen can get from the lungs into the blood.
- Conditions
- Interstitial Lung Disease, Chronic Obstructive Pulmonary Disease, Hypoxemia
- Trial name
- NCT07512687
- Testing
- Portable Oxygen Concentrator, Portable compressed oxygen D-tanks, No ambulatory oxygen therapy
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- State University of New York at Buffalo
Hypoxemia
Evaluation of the Melanin-Adjusted Blood Oxygen Sensor (MABOS) in ICU Settings
Purpose: Investigate the accuracy of the investigators' novel pulse oximeter across a broad range of skin-pigmentations and oxygen saturations.
- Trial name
- NCT07799454
- Testing
- MABOS
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of North Carolina, Chapel Hill
Hypoxemia, Postoperative Complications
Heated Humidified Oxygen in PACU Patients
This study aims to determine whether heated and humidified oxygen therapy, compared with conventional room-temperature oxygen therapy, reduces the incidence of early hypoxemia in adult patients recovering from general anesthesia…
- Conditions
- Hypoxemia, Postoperative Complications, Anesthesia Recovery Period
- Trial name
- NCT07778420
- Testing
- Heated and Humidified Oxygen Therapy, Room-Temperature Oxygen Therapy
- Where
- 8 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Hypoxemia
Reminder-enhanced Incentive Spirometry Evaluation
The purpose of this study is to test whether automatic reminders with a light and a soft sound help patients improve deep breathing exercises after surgery.
- Trial name
- RISE (NCT07728214)
- Testing
- Alarms ON
- Volunteers
- 88 people
- Sponsor
- University of Colorado, Denver
Acute Hypoxemic Respiratory Failure, Hypoxemia
Evaluation of the FreeO2 System for Oxygen Weaning After Acute Hypoxemic Respiratory Failure
Acute hypoxemic respiratory failure (AHRF) is a common condition associated with substantial morbidity, mortality, and healthcare resource utilization.
- Trial name
- EVOLUERA (NCT07794124)
- Testing
- FreeO2 automated oxygen titration system, Standard oxygen weaning
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Hypoxemia, Gastric Cancer (Diagnosis)
High-Flow Nasal Cannula Oxygenation During Sedated Gastrointestinal Endoscopy in Patients With Chronic Obstructive Pulmonary Disease
Hypoxemia is the most common adverse event during propofol sedation for gastrointestinal endoscopy in patients with chronic obstructive pulmonary disease (COPD) due to diminished pulmonary reserve.
- Conditions
- Hypoxemia, Gastric Cancer (Diagnosis), Chronic Obstructive Pulmonary Disease (COPD), Esophageal Cancer
- Trial name
- NCT07791979
- Testing
- High-flow nasal cannula
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Zhejiang University
COPD (Chronic Obstructive Pulmonary Disease), Hypoxemia
Inhaled Treprostinil (Tyvaso Nebulizer) For COPD Patients With Hypoxemia
The goal of this clinical trial is to evaluate whether inhaled Treprostinil (Tyvaso) can improve oxygen delivery and blood flow in the lungs in adults (age ≥40) with chronic obstructive pulmonary disease (COPD) and hypoxemia who…
- Trial name
- Tyvaso (NCT07037836)
- Testing
- Inhaled Treprostinil (Tyvaso Nebulizer)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Bastiaan Driehuys
Adverse Respiratory Events, Hypoxemia
Comparing Esketamine and Remazolam With Propofol for Breathing Safety in Pediatric Gastroscopy
Gastroscopy is important for diagnosing and treating upper gastrointestinal diseases in children. To ensure the procedure is safe and smooth, most children require sedation.
- Conditions
- Adverse Respiratory Events, Hypoxemia, Children, Gastroscopy
- Trial name
- NCT07748884
- Testing
- Fentanyl and Propofol, Esketamine and remimazolam
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Hypoxemia, Airway Management
Comparison of High-Flow Nasal Cannula and Tight Face Mask for Maintaining Oxygenation During Rapid Sequence Induction
This prospective randomized controlled trial aims to compare the effectiveness of High-Flow Nasal Cannula (HFNC) versus Tight Face Mask (TFM) in maintaining oxygenation during rapid sequence induction (RSI) for endotracheal…
- Conditions
- Hypoxemia, Airway Management, Endotracheal Intubation, Rapid Sequence Induction
- Trial name
- NCT07723430
- Testing
- High-Flow Nasal Cannula, Tight Face Mask
- Volunteers
- 290 people
- Sponsor
- Khyber Teaching Hospital
Procedural Sedation, Hypoxemia
HFNO Versus Face Mask for Cerebral Oxygenation During Procedural Sedation
This prospective randomized controlled trial aims to compare the effects of high-flow nasal oxygen (HFNO) and conventional face mask oxygen therapy on cerebral oxygenation during procedural sedation performed outside the…
- Conditions
- Procedural Sedation, Hypoxemia, Cerebral Oxygenation, SEDLine
- Trial name
- NCT07718295
- Testing
- High-Flow Nasal Oxygen (HFNO), Conventional Face Mask Oxygen
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Firat University
Endoscopic Retrograde Cholangiopancreatography, Hypoxemia
HFNC Versus Microstream Advance Nasal Cannula for Oxygenation During ERCP
Endoscopic retrograde cholangiopancreatography (ERCP) procedures are commonly performed under deep sedation and are associated with a risk of hypoxemia, particularly in prone or semi-prone positions.
- Trial name
- NCT07611903
- Testing
- High-flow nasal canula, Microstream advance nasal cannula
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Kocaeli University
Hypoxemia, Neonatal Disease
Evaluation of a Multi-country Medical Oxygen Program
REAL-MOXY is a set of 5 mixed methods studies designed to understand how oxygen and pulse oximetry are used (or not used) at a facility level, to identify opportunities and barriers for strengthening oxygen systems for…
- Conditions
- Hypoxemia, Neonatal Disease, Pneumonia, Sepsis
- Trial name
- REAL-MOXY (NCT06087315)
- Testing
- Multi-faceted oxygen systems strengthening interventions (different for each country)
- Where
- 3 sites in Cambodia, Nigeria and 1 more
- Volunteers
- 1,200 people
- Sponsor
- Murdoch Childrens Research Institute
Hypoxemia During Surgery
Effect of Preoxygenation Position and Examination Position on Hypoxemia During Painless Gastrointestinal Endoscopy
To investigate the independent effects and interaction of pre-oxygenation position (left lateral vs left lateral with 30° head-up tilt) and examination position (left lateral vs left lateral with 30° head-up tilt) on hypoxemia…
- Trial name
- NCT07673042
- Testing
- Pre-oxygenation Position （left lateral position）, Examination Position（left lateral position ）, Pre-oxygenation Position（ left lateral head elevation in a 30-degree position）
- Where
- China
- Volunteers
- 208 people
- Sponsor
- General Hospital of Ningxia Medical University
Postoperative Hypoxemia
Effect of Lateral Versus Supine Positions on Postoperative Hypoxemia
Using prospective real-world data, this study aims to determine whether the lateral decubitus position reduces the incidence of post-procedure hypoxemia in patients undergoing painless gastroscopy/colonoscopy, thereby providing a…
- Trial name
- NCT07545642
- Testing
- Lateral decubitus position group (Group L), Supine position group (Group S)
- Where
- China
- Volunteers
- 960 people
- Sponsor
- General Hospital of Ningxia Medical University
Chronic Respiratory Failure, Hypoxemia
Effects of Oxygen Supplementation During the 6-Minute Walk Test in Chronic Respiratory Failure or Exertional Hypoxemia
The aim of this multicenter crossover trial is to describe the effect of adding a therapeutic dose of exertional oxygen therapy, in terms of exercise performance, gas exchange, heart rate, symptoms perception and subjective…
- Conditions
- Chronic Respiratory Failure, Hypoxemia, Chronic Obstructive Pulmonary Disease (COPD), Interstitial Lung Disease
- Trial name
- NCT07451977
- Testing
- Usual Oxygen During 6-Minute Walk Test, Supplemental Oxygen During 6-Minute Walk Test
- Where
- 6 sites in Italy
- Volunteers
- 114 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA