Clinical trials: Hysterectomy, Vaginal
Vaginal Hysterectomy, Laparoscopic Supracervical Hysterectomy
Vaginal Hysterectomy vs Supracervical Hysterectomy at the Time of Sacrocolpopexy
The primary objective of the proposed study is to determine the difference in surgical time between minimally invasive (laparoscopic) sacrocolpopexy performed with concurrent vaginal hysterectomy versus laparoscopic supracervical…
- Trial name
- ColoplastLSC (NCT04797585)
- Testing
- Laparoscopic supracervical hysterectomy, Vaginal hysterectomy
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- The Cleveland Clinic
Hysterotomy; Affecting Fetus
Effect of Preventive Analgesia by Injection of a Local Anesthetic Before Vaginal Incision for Hysterectomy by vNOTES Approach
The research procedure is the injection of 20 mL of Ropivacaine solution (vs. saline) to create a paracervical block at the beginning of surgery, while the patient is already under general anesthesia.
- Trial name
- ANOTES (NCT05969457)
- Testing
- Naropeine, questionnaires
- Where
- 2 sites in France
- Volunteers
- 108 people
- Sponsor
- University Hospital, Rouen
Surgical Wound Dehiscence
Vaginal Cuff Dehiscence Following Total Laparoscopic Hysterectomy: Laparoscopic vs. Transvaginal Cuff Closure
Post-hysterectomy vaginal cuff dehiscence is a rare but threatening complication. The investigators will compare transvaginal versus laparoscopic closure of the vaginal vault at the end of a total laparoscopic hysterectomy, in…
- Trial name
- NCT02453165
- Testing
- TRANSVAGINAL SUTURE, LAPAROSCOPIC SUTURE
- Where
- Italy
- Volunteers
- 1,408 people
- Sponsor
- Università degli Studi dell'Insubria
Total Laparoscopic Hysterectomy, Benign Conditions
Comparison of Two Methods of Vaginal Cuff Closure at Laparoscopic Hysterectomy
American Congress of Obstetricians and Gynecologists (ACOG) advises minimally invasive methods in gynecological surgery to ensure increased benefits to the patient and reduce potential hospitalization costs.
- Trial name
- NCT02293369
- Testing
- Cuff closure via vaginal route, Cuff closure via laparoscopic route
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Istanbul University
Leiomyoma, Adenomyosis
Health-Related QoL Among Women Receiving Hysterectomy in NTUH
Laparoscopic assisted vaginal hysterectomy (LAVH)has become the most prevalent operation method in woman suffering from uterine myoma or adenomyosis nowadays.
- Trial name
- NCT00155870
- Testing
- questionnaires
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Taiwan University Hospital
UTERINE LEIOMYOMA
Influence of Aromatase Inhibitors and GnRH Analogs to Treat Uterine Leiomyoma by Vaginal Hysterectomy
The investigators aimed to assess if use of aromatase inhibitors could decrease volume of uterine leiomyoma and cause same percentage of adverse effects during its use compared to GnRH analogs.
- Trial name
- NCT01280045
- Testing
- VAGINAL HYSTERECTOMY
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Hysterectomy, Cellulitis
Prevention of Vaginal Cellulitis or Vaginal Cuff Abscess After Laparoscopic Hysterectomy
Operative site infection remains the most common complication after performing a gynecological procedure, and has a great implication in the morbidity and mortality of patients.
- Conditions
- Hysterectomy, Cellulitis, Vaginosis, Abscess
- Trial name
- NCT03917134
- Testing
- cephalosporin + Metronidazole Vaginal
- Where
- 2 sites in Colombia
- Volunteers
- 600 people
- Sponsor
- CES University
Hysterectomy, Benign Uterine Diseases, Hysterectomy, Vaginal
Effect of Abdominal Ice Pack After vNOTES Hysterectomy
This randomized, controlled, open-label, parallel-group clinical trial is designed to investigate the efficacy of abdominal ice pack application as an adjunct to standard pain management following vNOTES (Vaginal Natural Orifice…
- Conditions
- Hysterectomy, Benign Uterine Diseases, Hysterectomy, Vaginal, vNOTES, Postoperative Pain Following Hysterectomy
- Trial name
- NCT07626684
- Testing
- Abdominal Ice Pack + ERAS
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people
- Sponsor
- Erzincan Military Hospital
Hysterectomy
The Effect of Vertical Versus Horizontal Vaginal Cuff Closure on Vaginal Length After Laparoscopic Hysterectomy
This study has been designed as a prospective randomized trial to be performed at Bridgeport Hospital. Patients planning to undergo a laparoscopic or robotically assisted total laparoscopic hysterectomy with or without removal of…
- Trial name
- NCT02276261
- Testing
- Vaginal cuff closure - vertical, Vaginal cuff closure - horizontal
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Bridgeport Hospital
Postoperative Pain
Vaginal Hysterectomy, Laparoscopic Hysterectomy, Postoperative Pain
The previous studies have shown that recovery after laparoscopic or vaginal hysterectomy is faster than after abdominal approach. The aim of this study is to evaluate postoperative pain after vaginal or laparoscopic hysterectomy.
- Trial name
- NCT01442961
- Testing
- laparoscopy, laparoscopic hysterectomy, vaginal : vaginal hysterectomy
- Where
- Finland
- Volunteers
- 188 people
- Sponsor
- Tampere University Hospital
Pelvic Organ Prolapse
Unilateral Versus Bilateral High Uterosacral Ligament Suspension Following vNOTES Hysterectomy for Apical Pelvic Organ Prolapse: A Prospective Study
This study aims to compare unilateral and bilateral high uterosacral ligament suspension techniques performed following vaginal hysterectomy in patients with pelvic organ prolapse.
- Trial name
- HUSLS (NCT07552337)
- Testing
- High Uterosacral Ligament Suspension
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Hysterectomy
Investigation of the Incidence of Complications After Vaginal and Abdominal Hysterectomy
The purpose of this study is to evaluate the short and long term complications after an abdominal or vaginal hysterectomy and to detect the prevalence of occult/subclinical haematomas and vaginal cuff abscesses and the…
- Trial name
- NCT00181311
- Testing
- hysterectomy
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Maasland Hospital
Postoperative Urinary Retention
The Role of Sugammadex in Posotoperative Urinary Retention in Patients Undergoing Pelvic Floor Reconstructive Procedures
The Investigator will perform a single-institution randomized double-blinded controlled trial comparing intraoperative Sugammadex vs.
- Trial name
- NCT05664633
- Testing
- Sugammadex
- Sponsor
- West Virginia University
Pain, Postoperative, Postoperative Nausea and Vomiting
Local Infiltration Analgesia With Ropivacaine Versus Placebo in Vaginal Hysterectomy: a Randomized, Double-Blind Study
The purpose of this study is to compare systematic local infiltration with Ropivacaine 0.5 % vs. Placebo in patients undergoing vaginal hysterectomy.
- Trial name
- NCT00768456
- Testing
- Ropivacaine 0.5 %, Isotonic NaCl
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Hvidovre University Hospital
Pain, Postoperative
The Effect of Local Anesthesia on Postoperative Pain in Vaginal Hysterectomy
The investigators aim is to study the effect of pre-operative local anesthetic on post vaginal hysterectomy pain.
- Trial name
- NCT03268525
- Testing
- Marcaine 0.5 % Injectable Solution, Sodium Chloride 0.9%
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Hysterectomy
Barbed Versus Conventional Sutures for Vaginal Cuff Closure During Total Laparoscopic Hysterectomy
The aim of this study is to estimate whether the use of the barbed suture facilitates laparoscopic suturing of the vaginal cuff during total laparoscopic hysterectomy.
- Trial name
- NCT02998658
- Testing
- Vaginal cuff closure using barbed sutures, Vaginal cuff closure using conventional sutures
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Cairo University
Gynecologic Disease, Inflammation
Inflammatory Markers in Natural Orifice Hysterectomies
The authors aimed to detect inflammatory marker changes in two natural orifice hysterectomies: single-port laparoscopic hysterectomy (SLH) and vaginal hysterectomy (VH).
- Trial name
- NCT04221308
- Testing
- Single port laparoscopic systems
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people
- Sponsor
- Derince Training and Research Hospital
Hysterectomy, Natural Orifice Transluminal Endoscopic Surgery
Vaginal NOTES Hysterectomy Versus Vaginal Hysterectomy
Rationale: Natural orifice transluminal endoscopic surgery (NOTES) is a minimal invasive technique using the natural body orifices like stomach, oesophagus, bladder, rectum and vagina to access the human body for surgery.
- Conditions
- Hysterectomy, Natural Orifice Transluminal Endoscopic Surgery, Vaginal Hysterectomy
- Trial name
- VANH (NCT04886791)
- Testing
- Vaginal NOTES hysterectomy, Vaginal hysterectomy
- Where
- 2 sites in Netherlands
- Volunteers
- 124 people
- Sponsor
- Zuyderland Medisch Centrum
Hysterectomy
Single-dose Vaginal Dinoprostone and Hysterectomy
In this study, we will assess the efficacy of dinoprostone in minimizing blood loss during hysterectomy when used as a single preoperative dose via the vaginal route.
- Trial name
- NCT04080323
- Testing
- Dinoprostone 3 mg
- Where
- Egypt
- Volunteers
- 118 people
- Sponsor
- Cairo University
Laparoscopy
Cardiovascular Effects of the Degree of Head-down and Pneumoperitoneum During Laparoscopy
The aim of this study is to observe the cardiovascular effects of the degree of head-down angle and pneumoperitoneum during laparoscopic procedure using by the fourth version Vigileo-Flotrac system.
- Trial name
- NCT02129959
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- National Taiwan University Hospital