Clinical trials: Hysterectomy, Vaginal
Hysterectomy
Utility of the GoPro Hero 3 Camera as an Educational Tool For Vaginal Surgical Skills
Utilization of the GoPro camera to facilitate vaginal surgical education among residents and medical students
- Trial name
- NCT02669537
- Testing
- GoPro Camera
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Pelvic Organ Prolapse, Hysterectomy
Evaluation of the Relationship Between Vaginal and Lower Urinary Tract Microbiomes and Infection After Hysterectomy
The purpose of this study is to learn more about the microbes (bacteria) that live in the vagina and the bladder. The investigators are doing this research study to understand the relationship between microbes (the microbiome)…
- Conditions
- Pelvic Organ Prolapse, Hysterectomy, Urinary Tract Infection
- Trial name
- NCT02751073
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Mayo Clinic
Pelvic Organ Prolapse, Gynecologic Disorders
Comparison of Learning Curves for Two Different Techniques in Vaginal Hysterectomy
Randomized prospective monocentric interventional study to compare learning curves for traditional vaginal hysterectomy and vaginal hysterectomy performed by bipolar coagulation comparing short-term outcomes for both procedures.
- Conditions
- Pelvic Organ Prolapse, Gynecologic Disorders, Surgery
- Trial name
- NCT06220253
- Testing
- vaginal hysterectomy by bipolar vessels sealing, vaginal hysterectomy by traditional technique
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Benign Uterine Disease
LESS-TLH Versus LESS-LAVH
During the last 2 decades, several studies have tried to define the best surgical approach to hysterectomy for benign uterine diseases1.
- Trial name
- NCT01861067
- Testing
- LESS-TLH, LESS-LAVH
- Where
- South Korea
- Volunteers
- 76 people
- Sponsor
- CHA University
Vaginal Bleeding
Fitostimoline Vaginal Pessaries in Women With Hysterectomy. Randomized, Perspective, Monoscentric Study.
Clinical evaluation of Fitostimoline vaginal pessaries in the treatment of hysterectomy. An observational, randomized, perspective study performed on 60 women where 30 women are treated with fitostimoline pessaries and 30 women…
- Trial name
- NCT04612881
- Testing
- fitostimoline vaginal pessaries, standard of care
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Milan
Modified Extraperitoneal Uterosacral Ligament Suspension, Vault Prolapse, Vaginal
Modified Uterosacral Ligament Suspension in Vaginal Hysterectomy
Introduction : The extraperitoneal uterosacral ligament suspension (ULS) can be performed during the removal of the uterus in vaginal hysterectomy to prevent cuff prolapse.
- Trial name
- NCT03832543
- Volunteers
- 40 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Pelvic Organ Prolapse
Laparoscopic Sacropexy and Vaginal Natural Orifice Transluminal Endoscopic Surgery Shull Suspension Comparison Trial
This is a prospective, randomized multicenter study whose objective is to compare two surgical techniques routinely used at our center for the correction of pelvic organ prolapse (laparoscopic cervicosacropexis versus…
- Trial name
- V-PULSE (NCT05856201)
- Testing
- Laparoscopic cervicosacropexy, Shull technique via V-NOTES
- Volunteers
- 90 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Gynecologic Cancers, Vaginal Cuff Dehiscence
Comparison of Self-Locking Versus Traditional Sutures in Double-Layer Laparoscopic Vaginal Vault Closure After Hysterectomy (BI-SURE Trial)
Vaginal vault closure after laparoscopic or robotic hysterectomy may be associated with postoperative complications such as vaginal cuff dehiscence, infection, and bleeding.
- Conditions
- Gynecologic Cancers, Vaginal Cuff Dehiscence, Postoperative Complications
- Trial name
- BI-SURE (NCT07313839)
- Testing
- Double-Layer Vaginal Vault Closure with Self-Locking Suture, Double-Layer Vaginal Vault Closure with Polyglactin 910
- Where
- 5 sites in Italy
- Volunteers
- 310 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Pelvic Organ Prolapse
Permanent Versus Absorbable Colpopexy Trial
Primary Aim: The primary aim of this randomized controlled trial (RCT) is to compare vaginal mesh and suture exposure rates in women undergoing robotic total hysterectomy and sacrocolpopexy with a light-weight polypropylene mesh…
- Trial name
- PACT (NCT02277925)
- Testing
- Polytetrafluoroethylene, Polydioxanone
- Where
- 5 sites in United States
- Volunteers
- 204 people
- Sponsor
- University of North Carolina, Chapel Hill
Uterine Fibroids, Hysterectomy
Predictors of Success and Failure of v-NOTES Hysterectomy for Large and Very Large Uteri
Uterine fibroids are the most common benign tumors in women of reproductive age and are a major indication for hysterectomy. This retrospective, single-center observational study aims to identify factors associated with the…
- Conditions
- Uterine Fibroids, Hysterectomy, Vaginal Natural Orifice Transluminal Endoscopic Surgery (v-NOTES)
- Trial name
- PRE v-NOTES (NCT07895953)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Strasbourg, France
Laparoscopic Hysterectomy, Vaginal Infection
Vaginal Stump Infection After Laparoscopic Hysterectomy
Comparing two surgical techniques in relation to vaginal stump infection, analysis of patient-based and therapy-based risk factors.
- Trial name
- CoToIn (NCT04725981)
- Testing
- Total laparoscopic hysterectomy
- Where
- Switzerland
- Volunteers
- 141 people
- Sponsor
- Spital Limmattal Schlieren
Endometrial Cancer, Brachytherapy
A Novel Tapered Applicator for Vaginal Vault Brachytherapy
This study will assess the comfort and fit of a novel applicator for endometrial cancer patients who are candidates for vaginal brachytherapy. This study is only assessing the applicator fitting.
- Conditions
- Endometrial Cancer, Brachytherapy, Quality of Life
- Trial name
- NCT04318340
- Testing
- Tapered applicator, Standard applicator
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Yale University
Postoperative Pain Management
Vaginal Cuff Bupivacaine Injection for Postoperative Pain
This randomized controlled study evaluates whether injecting bupivacaine into the vaginal cuff during vaginal hysterectomy reduces postoperative pain. Vaginal hysterectomy is commonly performed for benign gynecologic conditions.
- Trial name
- marcaine (NCT07426666)
- Testing
- Bupivacaine %0.25 (isobaric)
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Havva Betül Bacak
Chronic Postsurgical Pain
Vaginal or Laparoscopic Hysterectomy, Persistent Postsurgical Pain
Previous studies have shown that chronic pain after hysterectomy is common. The aim of this study is to investigate the incidence of chronic pain after vaginal or laparoscopic hysterectomy for benign reasons.
- Trial name
- NCT01537731
- Testing
- vaginal or laparoscopic hysterectomy
- Where
- Finland
- Volunteers
- 225 people
- Sponsor
- Tampere University Hospital
Prolapse Pelvic, Hysterectomy
Vaginal Natural Orifice Transluminal Endoscopic (vNOTE) Hysterectomy With Uterosacral Suspension
As the adoption of Vaginal natural orifice transluminal endoscopic surgery (vNOTES) expands, attention is shifting from feasibility studies to the refinement of surgical steps that optimize long-term pelvic health.
- Trial name
- VENUS (NCT07413861)
- Testing
- Uterosacral suspension, Hysterectomy by vNOTES approach
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Vaginal Hysterectomy
Are Sutures Required for Vaginal Hysterectomy: A Randomized Controlled Trial
The hypotheses of this study is that the use of the instrument "Harmonic Scalpel" (ultrasonic shears) for vaginal hysterectomy instead of traditional sutures confers advantage over the use of traditional clamps and sutures.
- Trial name
- HAVE (NCT00456170)
- Testing
- Performing Vaginal hysterectomy with Harmonic Scalpel
- Where
- Australia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Southern Health
Fibroid, Uterine Corpus Smooth Muscle Neoplasm
Evaluation of Ultrasound-guided Transuterine Vaginal Biopsy Technique in Uterine Fibromatous Disease
The goal of this diagnostic, prospective study is to evaluate an innovative, minimally invasive surgical technique for diagnosing uterine smooth muscle tumors by biopsy, in women aged 18 and more, and to evaluate complications…
- Trial name
- EFIBIA (NCT06576362)
- Testing
- Echoguided transuterine vaginal biopsy performed before myomectomy or hysterectomy
- Volunteers
- 250 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Disease (or Disorder); Gynecological
Vaginal Cuff Closure Time Using Unidirectional Barbed Suture in Robotic Hysterectomy
This study is designed to determine if using the V-Loc Wound Closure System expedites operative time in robotic hysterectomy.
- Trial name
- NCT01814579
- Testing
- Unidirectional Barbed Suture (V-Loc), polyglactin 910 (Vicryl)
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of Tennessee
Uterine Prolapse
Comparison of Laparoscopic to Vaginal Surgical Repair for Uterine Prolapse
Investigators intend to conduct a prospective randomized trial to compare vaginal hysterectomy with uterosacral colposuspension to laparoscopic supracervical hysterectomy with sacrocervicopexy.
- Trial name
- NCT01594372
- Testing
- Laparoscopic supracervical hysterectomy with sacropexy, Vaginal hysterectomy with uterosacral colposuspension
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Brigham and Women's Hospital
Vaginal Hysterectomy
Do Patients Who Received Tranexamic Acid in Vaginal Hysterectomy Loose Les Blood, Comparing to Patients Who Did Not?
This is a randomized control, double-blind study in which women who are about to go an elective vaginal hysterectomy are offered to participate.
- Trial name
- NCT05921071
- Testing
- Tranexamic acid
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center