Clinical trials: Hysterectomy
Placenta Accreta
Comparison Between Hysterectomy and Conservative Management in Treatment of Placenta Accreta Regarding Maternal Complication
AIM OF THE WORK The aim of the study is to compare the maternal morbidity and mortality between obstetric hysterectomy and conservative surgery for pregnant ladies > 28 weeks with placenta accreta during caesarean section at Ain…
- Trial name
- NCT03327818
- Testing
- hysterectomy, uterine conservative study
- Volunteers
- 491 people
- Sponsor
- Ain Shams Maternity Hospital
Cervical Cancer, Cervical Cancer Stage IB1
Safety of Minimally Invasive Surgery Using Endoscopic Stapler in Early Stage Cervical Cancer Patients (SOLUTION)
The SOLUTION trial aims to show the efficacy and safety of performing radical hysterectomy by minimally invasive surgery using an endoscopic stapler in patients with cervical cancer stage IB1 (FIGO staging 2009) and thus to prove…
- Conditions
- Cervical Cancer, Cervical Cancer Stage IB1, Minimally Invasive Surgery
- Trial name
- SOLUTION (NCT04370496)
- Testing
- Minimally invasive surgery using endoscopic stapler
- Where
- 3 sites in South Korea
- Volunteers
- 124 people
- Sponsor
- Seoul National University Hospital
Endometrial Cancer, Endometrial Neoplasms
[SENTRY] Tailoring Postoperative Management Through Sentinel Lymph Node Biopsy in Low- and Intermediate-Risk Endometrial Cancer
While total hysterectomy without lymph node staging is standard for low- and intermediate-risk endometrial cancer, certain histopathologic factors can necessitate additional interventions.
- Conditions
- Endometrial Cancer, Endometrial Neoplasms, Endometrial Adenocarcinoma, Endometrial Cancer Stage I
- Trial name
- SENTRY (NCT04972682)
- Testing
- Laparoscopic total hysterectomy with bilateral salpingo-oophorectomy and sentinel lymph node biopsy
- Where
- Russia
- Volunteers
- 102 people
- Sponsor
- Moscow City Oncology Hospital No. 62
Cancer Uterus Cervix
Respiration After Robot Assisted Laparoscopic Hysterectomy
The study will investigate how respiratory function is affected by robot-assisted surgery. Previous studies have investigated the impact after open and laparoscopic surgery, but there are no studies yet after robot-assisted…
- Trial name
- REHYR (NCT06806280)
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Göteborg University
Uterine Prolapse, Pelvic Organ Prolapse Vaginal Surgery
The Finnish Uterine Prolapse Surgery Trial (The Fin-UP Trial)
The goal of this clinical trial is to compare the Manchester procedure and vaginal hysterectomy in treating patients with symptomatic uterine prolapse.
- Conditions
- Uterine Prolapse, Pelvic Organ Prolapse Vaginal Surgery, Pelvic Organ Prolapse (POP)
- Trial name
- Fin-UP (NCT07566949)
- Testing
- Manchester procedure, Vaginal hysterectomy
- Where
- 6 sites in Finland
- Volunteers
- 426 people
- Sponsor
- Tampere University Hospital
Total Abdominal Hysterectomy
S Ketamine Use in Total Abdominal Hysterectomy
This study investigates the effect of low dose S+ketamine compared to placebo on cumulative morphine consumption at 24 hours in women undergoing open abdominal hysterectomy with remifentanil-propofol target controlled infusion.
- Trial name
- SKET (NCT02543385)
- Testing
- S Ketamine
- Sponsor
- KK Women's and Children's Hospital
Post Operative Pain
Effect of Different Plane Blocks on Quality of Recovery and Postoperative Pain After Laparoscopic Hysterectomy
The goal of this clinical trial is to evaluate in effect of tap block and esp block on quality of recovery and postoperative pain after laparoscopic hysterectomy.
- Trial name
- NCT05780333
- Testing
- TAP block, ESP block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Mentese State Hospital
Postoperative Care, Pain Management
Effectiveness of Curcuminoids in Controlling Postoperative Pain Following Total Laparoscopic Hysterectomy
Total hysterectomy is one of the most common surgical procedures in gynecology. Total laparoscopic hysterectomy (TLH) has several advantages over open surgery, such as better cosmetic outcomes, faster recovery, and an earlier…
- Trial name
- NCT06886035
- Testing
- liposomal curcumin
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Pain Management
Analgesia Robotic Gynaecological Surgery
we will retrospectively investigate the effect of intratecal morphine administration on postoperative pain relief for patients scheduled for robotic hysterectomy
- Trial name
- NCT07169604
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Total Laparoscopic Hysterectomy, Patient-controlled Analgesia
Two-channel Intravenous Patient-controlled Analgesia (IV-PCA) After Total Laparoscopic Hysterectomy (TLH)
The purpose of this study is to compare the dual channel intravenous patient-controlled analgesia (IV-PCA) with single channel elastomeric pump (only one channel of dual channel pump is used for blinding and the other channel is…
- Trial name
- NCT04082039
- Testing
- convetional PCA method unsing only 1-channel, utilizing 2-channel
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Korea University Guro Hospital
Abdominal Hysterectomy
Intravenous Ascorbic Acid Administration in Hysterectomy
vitamin C or ascorbic acid has known role in tissue repair. due to it's properties(water_soluble), vitamin c is not stored in the body and when depleted, the bleeding tendency will increase due to dysfunctional connective tissues…
- Trial name
- NCT03965637
- Testing
- vitamin C
- Where
- Iran
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University
Carcinoma of the Endometrium, Hysterectomy
Lymphedema After Primary Surgery for Endometrial Cancer
The purposes of this study are to determine the prevalence, size and impact on quality of life of lymphedema of the lower extremities after primary radical surgery with hysterectomy +/- pelvic - and paraaortic lymphadenectomy in…
- Conditions
- Carcinoma of the Endometrium, Hysterectomy, Lymphadenectomy
- Trial name
- LASEC (NCT02115477)
- Testing
- Lymphadenectomy
- Where
- 16 sites in Sweden
- Volunteers
- 262 people
- Sponsor
- Preben Kjolhede, MD, professor
Gynecologic Neoplasms
Safety of Regular Diet as the First Meal in Patients Who Underwent Surgical Treatment for Gynecologic Cancer
The purpose of this study is to determine whether it is safe to give a regular diet as the first postoperative meal in patients who underwent surgical treatment for clinically early-stage gynecologic cancer.
- Trial name
- NCT00328757
- Testing
- Regular diet as the first postoperative meal
- Where
- Thailand
- Volunteers
- 240 people
- Sponsor
- Chiang Mai University
Vaginal Vault Prolapse
Prospective Study for Vaginal Vault Prolapse After Hysterectomy: Comparison of Two Surgical Methods
The study is carried out at the Sahlgrenska University Hospital and the patient population consists of women referred with symptomatic and bothersome post-hysterectomy vaginal vault prolapse at least 1 cm above or beyond the…
- Trial name
- NCT02290288
- Testing
- vaginal surgery, laparoscopic surgery
- Where
- Sweden
- Volunteers
- 138 people
- Sponsor
- Sahlgrenska University Hospital
Sleep, Pain
THE EFFECT OF HAND AND BACK MASSAGE ON PAIN, SLEEP AND SELF-CARE IN WOMEN UNDERGOING HYSTERECTOMY
Postoperative incision pain is an acute pain that begins with the stimulation of neuroreceptors from surgical trauma and usually resolves within a few days.
- Conditions
- Sleep, Pain, Self Efficacy
- Trial name
- NCT06403566
- Testing
- hand massage
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Cervical Cancer
A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer
This is a randomized controlled trial to compare survival for patients who undergoe robotic assisted laparoscopy versus open hysterectomy and lymph node assessment for the treatment of early stage cervical cancer.
- Trial name
- ROCC (NCT04831580)
- Testing
- da Vinci, open surgery
- Where
- 156 sites in United States, Brazil and 2 more
- Volunteers
- 840 people
- Sponsor
- GOG Foundation
Transversus Abdominis Plane Block From Abdominal Approach
Transversus Abdominis Plane Block From Abdominal Approach
Randomized double blind placebo controlled trial on transversus abdominus plane block approached from abdominal cavity, in patients undergoing total abdominal hysterectomy.
- Trial name
- NCT01144273
- Testing
- Transversus abdominis plane block
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- United Christian Hospital
Myoma of Uterus
Pain Characteristics After Total Laparoscopic Hysterectomy
Laparoscopic operative procedures have revolutionized gynecological surgery. These have several advantages: a smaller and more cosmetic incision, reduced blood loss and shorter postoperative stay, which cuts down on hospital…
- Trial name
- NCT01838382
- Testing
- classic LMA insertion
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Yonsei University
Constipation
Bowel Function After Minimally Invasive Hysterectomy
Postoperative constipation affects up to a third of women undergoing minimally invasive (MIS) gynecologic surgery and is a major source of anxiety and discomfort.
- Trial name
- NCT04263896
- Testing
- Polyethylene Glycol 3350
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Postoperative Hemorrhage
Lateral Occlusion of Uterine Artery in Total Laparoscopic Hysterectomy
Laparoscopic hysterectomy is associated with complications in form of infections and subsequently dehiscence of the vault. This is a serious complication.
- Trial name
- NCT02709460
- Testing
- Lateral occlusion, Cervical occlusion
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Odense University Hospital