Clinical trials: I-gel, open to volunteers
Supraglottic Airway Device
An in Vivo CT Imaging Study of GMA-Tulip, I-gel, and LMA Supreme (GLAM-II)
Laryngeal masks are core devices for supraglottic airway management, and the accuracy of their anatomical position directly impacts ventilation safety and the incidence of complications.
- Trial name
- GLAM-II (NCT07196696)
- Testing
- GMA-Tulip, I-gel, LMA-Supreme insertion
- Where
- 2 sites in China
- Volunteers
- 9 people
- Sponsor
- Zhejiang Cancer Hospital
Spinal Cord Injuries (SCI), Spinal Cord Injury
Guttmann NeuroRecovery - Viability, Safety, and Efficacy of Intrathecal Wharton's Jelly Mesenchymal Stem Cells and Transcutaneous Spinal Cord Stimulation in Chronic Spinal Cord Injury Rehabilitation
This clinical trial primarily aims to evaluate the safety and feasibility of a combined therapeutic approach for chronic spinal cord injury (SCI).
- Conditions
- Spinal Cord Injuries (SCI), Spinal Cord Injury, Traumatic Spinal Cord Injuries, Spinal Cord Disease
- Trial name
- GNR-SCI-01 (NCT06981338)
- Testing
- Allogeneic Wharton's jelly mesenchymal stem cells (WJ-MSCs)
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Institut Guttmann
Gastric Cancer With Peritoneal Dissemination
An Open Prospective Randomized Clinical Study of the Effectiveness, Tolerability and Safety of a Single Intraperitoneal Use of the Drug "Prospidelong, Powder for the Preparation of a Gel for Topical Use, 1000 mg in Vials, Package No. 1" in Patients With Disseminated Gastric Cancer, Phase I-II
It is planned to conduct an open-label, prospective, randomized clinical study of the efficacy, tolerability and safety of a single intraperitoneal administration of the investigational drug Prospidelong at a dose of 4000 mg…
- Trial name
- ИНТЕЛОН-02 (NCT06232434)
- Testing
- Prospidelong, chemotherapy
- Where
- Belarus
- Volunteers
- 120 people
- Sponsor
- Research Institute for Physical Chemical Problems of the Belarusian State University
Airway Management, Learning Curve
Comparison Between the I-gel and Protector Supraglottic Airway Devices
This study aims to compare the learning curves of two different laryngeal mask airway devices, by evaluating their placement in adult patients performed by anesthesiology residents
- Trial name
- NCT06938308
- Testing
- LMA Igel, LMA Protector
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nikolopoulou Maria Zozefin
Anesthesia
Electrical Acupoint Stimulation on Gastric Reflux During I-gel Ventilation
This study will compare the effects of transcutaneous acupoint electrical stimulation versus no stimulation on intraoperative gastric reflux in patients undergoing general anesthesia with i-gel airway device ventilation.
- Trial name
- ASGARD-igel (NCT07338448)
- Testing
- transcutaneous electrical acupoint stimulation, electrodes attachment
- Volunteers
- 116 people
- Sponsor
- Air Force Military Medical University, China
Airway Management Assessment, Supraglottic Airways
The Insertion of I-gel and Classic LMA in Different Head Positions in Elderly Patients
This prospective, randomized, double-blind clinical study aims to evaluate the insertion success of two supraglottic airway devices, the classic Laryngeal Mask Airway (LMA) and the I-gel, in different head and neck positions in…
- Conditions
- Airway Management Assessment, Supraglottic Airways, Supraglottic Airways for General Anesthesia, Laryngeal Mask Airways
- Trial name
- NCT07027293
- Testing
- STANDART HEAD POSITION, HEAD ROTATION POSITION, Classic laryngeal mask airway (LMA)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Gastric Insufflation, I-gel
Gastric Insufflation Volume Using I-gel Versus Ambu AuraGain in Pediatric Patients Undergoing Elective Orthopedic Operations Under General Anesthesia
Our study aimed to compare the gastric insufflation volume between Ambu AuraGain and i-gel and its relationship with the oropharyngeal sealing pressure and the incidence of postoperative complications in generally anesthetized…
- Conditions
- Gastric Insufflation, I-gel, Ambu AuraGain, Pediatric
- Trial name
- NCT06853756
- Testing
- Ambu Auragain, I-gel
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Locally Advanced Clear Cell Renal Cell Carcinoma, Locally Advanced Sarcomatoid Renal Cell Carcinoma
Inulin Gel in Combination With Ipilimumab and Nivolumab for the Treatment of Metastatic or Locally Advanced Kidney Cell Cancer, ICON Trial
This phase I/II trial tests the safety and effectiveness of inulin gel in combination with ipilimumab and nivolumab in treating patients with kidney cell cancer (renal cell carcinoma [RCC]) that has spread from where it first…
- Conditions
- Locally Advanced Clear Cell Renal Cell Carcinoma, Locally Advanced Sarcomatoid Renal Cell Carcinoma, Metastatic Clear Cell Renal Cell Carcinoma, Metastatic Sarcomatoid Renal Cell Carcinoma
- Trial name
- NCT06866262
- Testing
- Biopsy, Biospecimen Collection, Computed Tomography
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Michigan Rogel Cancer Center
Airway Management, General Anesthesia
LMA I-Gel Versus LMA Protector During Minor Urological Procedures Under General Anesthesia in Adult Patients
This will be a randomized comparative study comparing the two supraglottic devices i-gel and Protector, intraoperatively, during minor urological procedures under general anesthesia in adult patient.
- Trial name
- NCT06825910
- Testing
- LMA igel, LMA protector
- Where
- 2 sites in Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nikolopoulou Maria Zozefin
Hemodynamic Monitoring, Laryngeal Mask Success Rate
Comparison of I-gel and SaCoVLM in Laparoscopic Cholecystectomy
This prospective observational study aims to compare the ventilation performance and safety of the i-gel and SaCoVLM supraglottic airway devices in adult patients undergoing elective laparoscopic cholecystectomy.
- Conditions
- Hemodynamic Monitoring, Laryngeal Mask Success Rate, End Tidal Carbon Dioxide
- Trial name
- NCT07692139
- Volunteers
- 80 people
- Sponsor
- Samsun University
Nausea and Vomiting, Postoperative, Sore-throat
Comparison of Gastric Volume in I-gel and ProSeal Laryngeal Mask Airways
This study was planned to compare the gastric insufflation volume between i jel and ProSeal laryngeal mask airway (LMA) and its relationship with the oropharyngeal sealing pressure and the incidence of postoperative complications…
- Trial name
- NCT07138092
- Testing
- i jel LMA, proseal LMA
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Advanced Solid Tumor
Study of TRX-920 for Patients With Advanced Solid Tumors
The study drug TRX-920 Oral Gel contains SN38, an active metabolite of Irinotecan (CPT-11), which is a widely prescribed anti-cancer drug that has been approved in many countries for the treatment of colorectal and pancreatic…
- Trial name
- NCT06143774
- Testing
- TRX-920 Oral Gel (10 mg and 30 mg)
- Where
- 3 sites in Taiwan
- Volunteers
- 30 people
- Sponsor
- TaiRx, Inc.
Trauma Surgery, General Anesthesia
Comparison of the GMA-TULIP and I-gel Laryngeal Mask for Airway Management in General Anaesthesia: a Randomized Controlled Trial
The goal of this clinical trial is to learn if GMA-TULIP laryngeal mask willfit well in the right place in participants undergoing trauma surgery in a supine position under general anaesthesia.
- Trial name
- NCT07019961
- Testing
- the GMA-TULIP laryngeal mask, the i-gel laryngeal mask
- Where
- China
- Volunteers
- 198 people
- Sponsor
- Qilu Hospital of Shandong University
Chronic Rhinosinusitis With Nasal Polyps
Thermosensitive Gel Nasal Spray With Stem Cell Exosomes, Mupirocin, and DNase I for Chronic Sinusitis
This study tests a new nasal spray for adults (18-65 years) with chronic rhinosinusitis (CRS) without nasal polyps. The spray contains a temperature-sensitive gel (thermosensitive gel) that turns into a soft gel inside the nose…
- Trial name
- NCT07635433
- Testing
- Exosomes (hUC-MSC-Exo), Mupirocin, DNase I
- Volunteers
- 108 people
- Sponsor
- The First Affiliated Hospital of Xinxiang Medical College
Acute Ischemic Stroke AIS
The STem Cell-derived Extracellular Vesicle Therapy In Acute Ischemic Stroke (STEVIA)
This is a multicenter open-label, single-arm, dose escalation phase I clinical trial to evaluate the safety and tolerability of SNE-101 in patients with acute ischemic stroke
- Trial name
- STEVIA (NCT06995625)
- Testing
- SNE-101
- Where
- 3 sites in South Korea
- Volunteers
- 18 people
- Sponsor
- S&Ebio Co. Ltd.
Prostate Cancer
Single Fractions SBRT for Prostate Cancer
It is a phase I study of radical hypofractionation delivering one single fraction of SBRT in patients with low- and favorable intermediate-risk prostate cancer that will undergo placement of the SpaceOAR hydrogel prior to…
- Trial name
- NCT04004312
- Testing
- Stereotactic Body Radiation Therapy (SBRT)
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Fabio Cury