Clinical trials: IBD (Inflammatory Bowel Disease)
Crohn Disease, Pediatric Crohns Disease
PediCRaFT: Pediatric Crohn's Disease Fecal Transplant Trial
The objective of this study is to assess the feasibility of a novel colonic and oral fecal microbiota transplantation protocol for the treatment of active pediatric Crohn's disease (CD).
- Conditions
- Crohn Disease, Pediatric Crohns Disease, Inflammatory Bowel Diseases, Colitis
- Trial name
- PediCRaFT (NCT03378167)
- Testing
- MICROBIOTA
- Where
- 2 sites in Canada
- Volunteers
- 17 people
- Sponsor
- McMaster Children's Hospital
Inflammatory Bowel Diseases
Correlation Between RISANKIZUMAB's Trough Levels, Clinical and Biological Remission in Moderate to Severe Crohn's Disease: a Retrospective Multicentric Study
The goal of this observational study is to determine if, as with other therapeutics such as anti-TNF, trough levels of Risankizumab are correlated with clinical and biological remission in patients with moderate to severe Crohn's…
- Trial name
- RISE-CD (NCT06589895)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Ulcerative Colitis
Dynamic Changes of Gut Microbiota in UC After FMT
A prospective study to investigate the dynamic changes of gut microbiota through colonic transendoscopic enteral tubing in patients with ulcerative colitis after fecal microbiota transplantation.
- Trial name
- NCT03949257
- Testing
- colonic transendoscopic enteral tubing
- Where
- China
- Volunteers
- 20 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Crohn's Disease
Long-term Safety Study of Brodalumab in Adults With Crohn's Disease
The purpose of this study is to evaluate the safety and efficacy of long-term treatment with brodalumab in adults with Crohn's disease.
- Trial name
- NCT01199302
- Testing
- Brodalumab
- Where
- 34 sites in United States, Australia and 6 more
- Volunteers
- 67 people
- Sponsor
- Amgen
Insulin Resistance, Inflammatory Bowel Diseases
Nutraceutical Composition Containing Natural Products Derivatives on the Modulation of the Endocrine Neuroimmune Axis
The use of natural products in the prevention or treatment of chronic diseases is an emerging field in current medicine. And studying the mechanisms of actions by which natural products act in our bodies contributes to the…
- Conditions
- Insulin Resistance, Inflammatory Bowel Diseases, Overweight and Obesity, Healthy
- Trial name
- NCCNPDMENA (NCT04810572)
- Testing
- Composition with Silymarin, Low-mineral composition without Silymarin
- Where
- Brazil
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Crohn's Disease, Ulcerative Colitis
Body Composition in Children With Inflammatory Bowel Disease
Background: Growth impairment is commonly seen in children diagnosed with inflammatory bowel diseases (IBD), mainly those with Crohn's disease (CD).
- Trial name
- NCT02745457
- Where
- Israel
- Volunteers
- 72 people
- Sponsor
- Schneider Children's Medical Center, Israel
Colitis, Ulcerative, Crohn Disease
A Study to Assess Guselkumab in Participants With Moderate-to-Severe Inflammatory Bowel Disease in Real Life Italian Setting
The purpose of this study is to characterize participants with Crohn's Disease (CD) and Ulcerative Colitis (UC) receiving guselkumab in a real-world setting, and to evaluate treatment persistence (continuation) and clinical…
- Conditions
- Colitis, Ulcerative, Crohn Disease, Inflammatory Bowel Diseases
- Trial name
- GLAMOUR (NCT07851207)
- Volunteers
- 200 people
- Sponsor
- Janssen-Cilag Ltd.
Ulcerative Colitis
Health Benefits of Tart Cherry in Ulcerative Colitis
Ulcerative Colitis (UC) is a long-term inflammatory condition of the digestive tract. People with UC often have unpredictable and debilitating symptoms, including abdominal pain, diarrhoea and fatigue.
- Trial name
- NCT05486507
- Testing
- Montmorency tart cherry
- Where
- 2 sites in United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Central Lancashire
Inflammatory Bowel Diseases
Thalidomide Therapy for VEOIBD
This is a single center, observational study to investigate the clinical outcomes of thalidomide treatment for very early onset inflammatory bowel disease
- Trial name
- NCT06382519
- Testing
- Thalidomide
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Children's Hospital of Fudan University
Ulcerative Colitis
Study to Investigate Comparative Efficacy, Safety and Immunogenicity Between AVT16 and Entyvio
The study has been designed as a randomised, parallel-group, double-blind, 2 arm study of the comparative efficacy, safety and immunogenicity of AVT16 and Entyvio in male and female subjects with moderate to severe active…
- Trial name
- NCT06570772
- Testing
- AVT16, Vedolizumab
- Where
- 100 sites in Argentina, Bulgaria and 9 more
- Volunteers
- 301 people
- Sponsor
- Alvotech Swiss AG
Ulcerative Colitis
Evaluation of Early Mucosal Healing During Clinical Remission in Pediatric Ulcerative Colitis
Establishing that mucosal healing (MH) has occurred after therapy is an important treatment goal, and the gold standard is endoscopic evaluation. In UC it is unclear if clinical parameters are adequate.
- Trial name
- NCT03179865
- Where
- Israel
- Volunteers
- 28 people
- Sponsor
- Wolfson Medical Center
Crohn Disease
Effectiveness of Rifaximin Combined With Thiopurine on Preventing Postoperative Recurrence in Crohn's Disease
Some studies have shown that rifaximin is effective in the management of Crohn's Disease. Meanwhile, its adverse effect is tolerable. But no study has been conducted to assess its effect on preventing postoperative recurrence.
- Trial name
- NCT03185611
- Testing
- Rifaximin, Azathioprine
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Inflammatory Bowel Diseases, Crohn Disease
Personalized Research on Diet in Ulcerative Colitis and Crohn's Disease
A series of N-of-1 trials will be used to determine the effectiveness of a specific carbohydrate diet (SCD) versus a modified SCD in patients in reducing symptoms and inflammatory burden at both the individual and population…
- Conditions
- Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis, Indeterminate Colitis
- Trial name
- PRODUCE (NCT03301311)
- Testing
- Specific Carbohydrate Diet (SCD), Modified Specific Carbohydrate Diet (MSCD)
- Where
- 20 sites in United States
- Volunteers
- 54 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Crohn's Disease
The Effect on Mucosal Healing With Pentasa Sachet in Mild to Moderate Active "Drug: Crohn's Disease"
The purpose of this study is to visualize the healing effect on mucosal lesions with Pentasa Sachet 4g in patients with mild to moderate active small bowel CD by video capsule endoscopy.
- Trial name
- NCT00245505
- Testing
- Mesalazine (Mesalamine)
- Where
- Sweden
- Volunteers
- 3 people
- Sponsor
- Ferring Pharmaceuticals
Crohn's Disease, Ulcerative Colitis
Cannabidiol for Inflammatory Bowel Disease
There are many anecdotal reports about improvement of Inflammatory bowel diseases (IBD) with cannabis smoking. The most effective anti inflammatory compound known today is cannabidiol.
- Trial name
- NCT01037322
- Testing
- cannabidiol
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Meir Medical Center
Anemia, Iron Deficiency, Ulcerative Colitis
Sucrosomial Iron vs. Oral Iron Sulfate for the Treatment of Iron Deficiency Anemia in Patients With Ulcerative Colitis
The aim of the study is to compare the tolerability and efficacy of Sucrosomial Iron to Oral Iron Therapy in a randomized controlled trial for the treatment of Iron Deficiency Anemia in Ulcerative Colitis patients.
- Trial name
- NCT05225545
- Testing
- Sucrosomial Iron, Oral Iron
- Where
- Lebanon
- Volunteers
- 30 people
- Sponsor
- American University of Beirut Medical Center
Inflammatory Bowel Disease
Predictors of Mucosal Healing in Inflammatory Bowel Disease (IBD) Patients Treated With Anti-TNF
The aim of this study is to prospectively identify, at diagnosis of the disease, factors predictive of mucosal healing in patients with inflammatory bowel disease treated with anti-TNF.
- Trial name
- NCT01605175
- Where
- Greece
- Volunteers
- 21 people
- Sponsor
- Evangelismos Hospital
Ulcerative Colitis
Induction and Maintenance of Remission With Pentasa as Ulcerative Colitis Treatment
For both induction of remission and in maintenance of remission, different doses and treatment durations are used in practice. The aim of this study is to assess how mesalazine is used in clinical practice, at which doses and for…
- Trial name
- IMPACT (NCT02261636)
- Testing
- mesalazine
- Where
- Netherlands
- Volunteers
- 150 people
- Sponsor
- Ferring Pharmaceuticals
Chronic Pain, Fibromyalgia
Effects of Fasting on Self Efficacy
The study aims to investigate if a 7 day therapeutic fasting regimen will affect self-efficacy of patients with chronic diseases the effects of fasting on physical and mental well-being, quality of life and body awareness/image…
- Conditions
- Chronic Pain, Fibromyalgia, Rheumatoid Arthritis, Gout
- Trial name
- TheraFast (NCT02113111)
- Testing
- Fasting
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Universität Duisburg-Essen
Crohn's Disease
Infliximab Top-down in Pediatric Crohn
The purpose of this study is to determine whether a top-down treatment approach, prescribing infliximab and azathioprine at diagnose, yields better outcome in comparison to the usual step-up treatment approach, starting with…
- Trial name
- ITSKids (NCT01880307)
- Testing
- Azathioprine, Infliximab, Prednisolon
- Where
- 2 sites in Italy, Netherlands
- Volunteers
- 13 people
- Sponsor
- Erasmus Medical Center
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.