Clinical trials: IBD-Inflammatory Bowel Disease
Inflammatory Bowel Disease
MRI in Patients With Inflammatory Bowel Disease
The aim of this study is to find an optimal magnetic resonance imaging (MRI) method to examine patients with inflammatory bowel disease (IBD).
- Trial name
- NCT02255019
- Where
- Denmark
- Volunteers
- 125 people
- Sponsor
- Copenhagen University Hospital at Herlev
Inflammatory Bowel Disease
Characterization of Phenotype and Genotype of Early Onset Enteropathies
This study has been set up in order to characterize phenotypes and genotypes of patients with early onset enteropathies. In that goal, Investigators will collect biological samples (mainly blood) of patients suffering from early…
- Trial name
- IMMUNOBIOTA (NCT02614911)
- Testing
- Biological sampling
- Where
- 12 sites in France
- Volunteers
- 1,445 people, healthy volunteers welcome
- Sponsor
- Imagine Institute
Gastrointestinal Diseases
ESPRESSO (Epidemiology Strengthened by histoPathology Reports in Sweden)
The ESPRESSO study is a collection of data from all computerised gastrointestinal histopathology reports in Sweden. This allows us to study risk factors for gastrointestinal disease, as well as the prognosis of gastrointestinal…
- Trial name
- ESPRESSO (NCT06371820)
- Testing
- ESPRESSO [The study has no intervention]
- Volunteers
- 13,000,000 people
- Sponsor
- Karolinska Institutet
Primary Sclerosing Cholangitis, Inflammatory Bowel Disease
A Pilot Study to Characterize Bile Acid Metabolism and Dysbiosis in Primary Sclerosing Cholangitis
The goal of this study is to assess if oral vancomycin can restore the normal bile acid metabolism of people with Primary Sclerosing Cholangitis and Inflammatory Bowel Disease.
- Trial name
- NCT02464020
- Testing
- Vancomycin
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Minnesota
Crohn's Disease
Assessment of Small Bowel Healing in Crohn's Disease Patients Treated With Cimzia Using Wireless Capsule Endoscopy
Wireless Capsule Endoscopy has been the most reliable diagnostic standard for small bowel Crohn's disease. Endoscopic healing is an important endpoint to measure response to treatment.
- Trial name
- NCT01053559
- Testing
- certolizumab pegol
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Shafran Gastroenterology Center
Crohns Disease
Comparative Effectiveness of MR Enterography
The purpose of this study is to determine the efficacy of ultrasound imaging compared to MRE (Magnetic Resonance Enterography) a form of magnetic resonance imaging (MRI) in accurately diagnosing and following Small Bowel Crohn…
- Trial name
- NCT01593462
- Testing
- MRE (magnetic resonance enterography), The Ultrasound scan, (UEI) Ultrasound Elastography Imaging with ARFI (acoustic radiation force impulse), Study Questionnaires
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Michigan
Inflammatory Bowel Diseases, Crohn Disease
Implementing a Multimodal RCT Intervention to Improve the Transition of Patients With Crohn's Disease From Pediatric to Adult Care
Background: Transition in care is defined as the "purposeful and planned movement of adolescents and young adults with a chronic medical condition from pediatric to adult-oriented healthcare systems/care providers." Currently…
- Conditions
- Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis, Adolescent Development
- Trial name
- NCT05221281
- Testing
- Multimodal intervention consisting of four core components, Standard of care
- Where
- 3 sites in Canada
- Volunteers
- 90 people
- Sponsor
- The Hospital for Sick Children
Crohn Disease
A Study to Assess Whether Etrolizumab is a Safe and Efficacious Treatment for Participants With Moderately to Severely Active Crohn's Disease
This is a multicenter, Phase 3, double-blind, placebo-controlled study evaluating the efficacy, safety, and tolerability of etrolizumab compared with placebo during induction and maintenance treatment of moderately to severely…
- Trial name
- BERGAMOT (NCT02394028)
- Testing
- Etrolizumab
- Where
- 327 sites in United States, Argentina and 31 more
- Volunteers
- 1,035 people
- Sponsor
- Hoffmann-La Roche
Inflammatory Bowel Disease
Surgical Decision Making Among People With Inflammatory Bowel Disease
This is a study for people with inflammatory bowel disease ("IBD"--that is, ulcerative colitis, Crohn's colitis, or indeterminate colitis).
- Trial name
- NCT00438711
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- University of North Carolina, Chapel Hill
Ulcerative Colitis, Irritable Bowel Syndrome
Cerebral Resonance Magnetic Imaging During Rectal Distention
Irritable bowel syndrome is responsible for chronic abdominal pain, diarrhea and/or constipation. It is a very frequent problem. However, the exact cause of irritable bowel syndrome remains unknown.
- Trial name
- NCT00213330
- Testing
- rectal distension
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Crohn's Disease, Malnutrition
Assessment of Nutritional Status of Patients With Crohn's Disease
Good nutritional status of patients with Crohn's disease (CD) is associated with better outcome of the disease and better health-related quality of life.
- Conditions
- Crohn's Disease, Malnutrition, Overweight and Obesity, Sarcopenia
- Trial name
- NCT03871634
- Where
- Greece
- Volunteers
- 250 people
- Sponsor
- Harokopio University
Ulcerative Colitis, Crohn Disease
HMPL004-6599 Phase I Dose-escalating Study
To assess the safety and tolerability of single and multiple doses of HMPL004-6599 in healthy male volunteers
- Trial name
- NCT03597971
- Testing
- HMPL004-6599
- Where
- Australia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Nutrition Science Partners Limited
Ulcerative Colitis, Crohn's Colitis
RCT: HDWL vs Virtual Chromoendoscopy in the Detection of Intraepithelial Neoplasia in Longstanding Colitis
Colitis is inflammation of the large bowel and it is often caused by conditions known as ulcerative colitis and Crohn's disease.
- Trial name
- VIRTUOSO (NCT02822352)
- Testing
- Chromoendoscopy
- Where
- United Kingdom
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Portsmouth Hospitals NHS Trust
Crohn Disease
Effect of Prebiotic FOS on Intestinal Abundance of Faecalibacterium Prausnitzii in Patients With Crohn´s Disease
FOS improve gut colonization by Faecalibacterium prausnitzii in patients with Crohn's disease
- Trial name
- NCT02539849
- Testing
- FOS, Adalimumab
- Where
- 5 sites in Spain
- Volunteers
- 38 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Crohn Disease, Colitis, Ulcerative
A Study of Continued Use of Guselkumab in Participants With Crohn's Disease and Ulcerative Colitis in Real World Setting
The purpose of this study is to find out how long a participant keeps taking guselkumab or continues with their treatment plan without stopping (treatment persistence) in participants with moderate to severe Crohn's disease (CD)…
- Trial name
- GusTaCon (NCT07746765)
- Volunteers
- 35 people
- Sponsor
- Janssen Sciences Ireland UC
Inflammatory Bowel Diseases, Crohn Disease
Telemonitoring for IBD Goodness Examination in Russia
This is a prospective, randomized study to assess the impact of telemedicine (telemonitoring, tele-education and tele-consultation) on the patients with Inflammatory Bowel Disease (IBD).
- Conditions
- Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis
- Trial name
- TIGE-Rus (NCT05994716)
- Testing
- Telemonitoring
- Where
- Russia
- Volunteers
- 62 people
- Sponsor
- Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department
Crohn's Disease
Safety and Tolerability of FITC-Adalimumab Administration During Confocal Laser Endomicroscopy of the Gut
The scientific objective of the project is to evaluate if the topical administration of Fluoresceinisothiocyanate (FITC)-Adalimumab during the endomicroscopic examination of the gut in Crohn's disease (CD) patients shows an…
- Trial name
- FA-Crohn (NCT01275508)
- Testing
- FITC-Adalimumab
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Ulcerative Colitis
Efficacy, Safety and Immunogenicity of the Proposed Biosimilar Vedolizumab PB016 in Comparison With Entyvio®
This is a multi-center, randomized, parallel arm, double-blind study with approximately 750 participants with moderately to severely active Colitis Ulcerosa randomized to receive either PB016 or Entyvio®
- Trial name
- UCESIVE (NCT05771155)
- Testing
- Intravenous (IV) infusions
- Where
- Georgia
- Volunteers
- 750 people
- Sponsor
- Polpharma Biologics S.A.
Ulcerative Colitis
Efficacy, Safety and Tolerability of AEB071 in Patients With Active, Moderate to Severe Ulcerative Colitis
This study will evaluate the efficacy, safety and tolerability of AEB071 in the treatment of active, moderate to severe ulcerative colitis in patients who have failed conventional therapy using mesalamine or steroids
- Trial name
- NCT00572585
- Testing
- AEB071
- Where
- 20 sites in United States, Denmark and 2 more
- Volunteers
- 60 people
- Sponsor
- Novartis Pharmaceuticals
Ulcerative Colitis
Safety and Efficacy of PBF-677 in Ulcerative Colitis Patients
This is a Phase IIa (proof of concept), randomized, double blind, placebo-controlled, multicentre clinical trial to evaluate the safety and efficacy of daily PBF-677 oral treatment during 28 days in Ulcerative colitis (UC)…
- Trial name
- ADENOIBD (NCT03773952)
- Testing
- PBF-677
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Palobiofarma SL
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