Clinical trials: IBD-Inflammatory Bowel Disease
Crohn Disease, Polyposis
Clinical Database of Colorectal Robotic Surgery
Evaluation of robot Da Vinci Xi by determining its learning curve.The operating time will be defined by patient then the operating average will be calculated.
- Conditions
- Crohn Disease, Polyposis, Ulcerative Colitis, Diverticulitis
- Trial name
- ROBOT CR (NCT04013152)
- Testing
- Clinical database
- Where
- 4 sites in France
- Volunteers
- 1,800 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Ulcerative Colitis
The Efficacy and Safety of Combining Probiotic VSL#3 With Vedolizumab for the Treatment of Moderate Ulcerative Colitis
An imbalance in the gut microbiota and mucosal immune dysfunction leading to intestinal inflammation are central to the pathogenesis of ulcerative colitis (UC).
- Trial name
- NCT06609447
- Testing
- VSL#3, Vedolizumab
- Where
- 12 sites in China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Ulcerative Colitis
Randomized,Study of APRISO 375 mg Versus the Approved APRISO 375 mg Capsules in Healthy Male and Female Subjects
The objective of this study is to evaluate and compare the bioavailability of mesalamine
- Trial name
- NCT03327558
- Testing
- Apriso 0.375G ER CAP, APRISO 375 mg extended-release capsules
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bausch Health Americas, Inc.
Crohn Disease of Ileum
Ileocolic Resection for Complex Crohn's Disease
Laparoscopic ileocolic resection is the preferred surgical approach for patients with ileocecal Crohn's disease (CD). Objective of this study was to evaluate the efficacy of a minimally invasive gas-less ileocolic resection in…
- Trial name
- NCT03950726
- Testing
- ileocolic resection
- Volunteers
- 27 people
- Sponsor
- University of Roma La Sapienza
Inflammatory Bowel Diseases
Azathioprine Linked With Impaired Intestinal Epithelial Postoperative Regeneration in Crohn's Disease
What is known? the impact of AZA, immunomodulatory drug widely used in active CD, on the intestinal wall differs from those of steroids, what is reflected in the significant difference in the postoperative anastomotic leaks rate…
- Trial name
- NCT05456776
- Volunteers
- 35 people
- Sponsor
- Centre of Postgraduate Medical Education
Ulcerative Colitis
Effect of Aloe Vera in the Inflammation of Patients With Mild Ulcerative Colitis
The Ulcerative Colitis (UC) belongs to the group of diseases called Inflammatory Bowel Disease (IBD) which is characterized by a chronic ulceration of the colon.
- Trial name
- AVIUC (NCT01783119)
- Testing
- Aloe Barbadensis Miller
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- National Institute of Medical Sciences and Nutrition, Salvador Zubiran
Crohn's Disease
The MOTOR-CD Trial
Both single-balloon enteroscopy (SBE) and novel motorized spiral enteroscopy (NMSE) are effective techniques for small bowel endoscopy in suspected Crohn's disease (CD).
- Trial name
- NCT05363930
- Testing
- Novel motorized spiral enteroscopy, Single balloon enteroscopy
- Where
- India
- Volunteers
- 128 people
- Sponsor
- Asian Institute of Gastroenterology, India
Crohn's Disease
Observational Study Evaluating the Effectiveness of Drug Concentration to Predict the Recapture of Response in Crohn's Disease Patients With Loss of Response ( PRADA )
This is a multi-center study that explores the relationship between recapture of response with escalation to weekly adalimumab and trough adalimumab concentration before escalation in patients experiencing lack of response (LOR).
- Trial name
- PRADA (NCT02896985)
- Where
- 24 sites in Canada
- Volunteers
- 98 people
- Sponsor
- AbbVie
Fatigue, Inflammatory Bowel Disease
Electroacupuncture vs. Sham Electroacupuncture for Treatment of Fatigue in Patients With Inflammatory Bowel Disease
Fatigue is a common symptom in inflammatory bowel diseaseI and persists despite clinical remission. Fatigue in patients with chronic diseases can be objectified by the FACIT-F scale.
- Trial name
- NCT02733276
- Testing
- electroacupuncture
- Where
- Spain
- Volunteers
- 54 people
- Sponsor
- Corporacion Parc Tauli
Crohn Disease
The CROCO Study: CROhn's Disease COhort Study
The investigators propose to create a prospective Crohn Disease cohort, where patients receiving the most up-to-date therapies with a treat-to-target strategy, will be closely followed to characterize the progression of Crohn…
- Trial name
- CROCO (NCT05420233)
- Testing
- MRE
- Where
- 19 sites in Belgium, Cyprus and 9 more
- Volunteers
- 533 people
- Sponsor
- GLSMED Learning Health S.A.
Crohn Disease
Fecal Microbiota Transplantation as the First-line Treatment in Active Pediatric Crohn's Disease
To explore the safety and effectiveness of repeated and multiple fecal microbiota transplantations (FMTs) plus partial enteral nutrition (PEN) as a first-line treatment for active Crohn's disease (CD) in children.
- Trial name
- FMT (NCT05321758)
- Testing
- Fecal Microbiota Transplantation, Immunosuppressive Agents
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Inflammatory Bowel Disease (IBD), Hepatitis B Virus
Impact of Hepatitis B Virus on Inflammatory Bowel Disease
The goal of this observational retrospective study is to assess the impact of hepatitis B virus (HBV) infection on the clinical course and outcomes of inflammatory bowel disease (IBD) in Egyptian patients.
- Trial name
- NCT06881238
- Testing
- History of IBD course and outcome in HBV patients
- Where
- Egypt
- Volunteers
- 162 people
- Sponsor
- Tanta University
Crohn Disease, Pediatric Inflammatory Bowel Diseases
Microplastic Analysis in Pediatric Inflammatory Bowel Disease
The goal of this observational study is to measure and compare the presence of microplastics in children with inflammatory bowel disease (IBD) and children without IBD.
- Conditions
- Crohn Disease, Pediatric Inflammatory Bowel Diseases, Ulcerative Colitis (UC), Inflammatory Bowel Disease (IBD)
- Trial name
- MAP-IBD (NCT07141238)
- Testing
- Environmental microplastic exposure
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Medical University of Gdansk
Post-COVID-19 Condition, Ulcerative Colitis
Emerging Indications for Hyperbaric Oxygen Treatment
This study will evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) on treating emerging indications (i.e., conditions that have shown to potentially benefit from HBOT) using the Multicenter Registry for Hyperbaric…
- Conditions
- Post-COVID-19 Condition, Ulcerative Colitis, Crohn Disease, Calciphylaxis
- Trial name
- NCT07240649
- Testing
- Hyperbaric oxygen treatment (HBOT), 100% Oxygen
- Volunteers
- 100 people
- Sponsor
- Jay C. Buckey Jr.
Crohn's Disease, Ulcerative Colitis
Prevalence of Cytomegalovirus, Epstein Barr Virus and Human Herpes 6 Virus in Inflammatory Bowel Disease
An increase prevalence of CMV, EBV and or HHV-6 in diseased tissue of inflammatory bowel disease would suggest a role for these viruses in the etiology and/or exacerbation of IBD, whereas their absence would preclude such…
- Trial name
- NCT00222378
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- University of Miami
Spondylarthritis, Inflammatory Bowel Diseases
Spondylo-arthritis Screening Tool Among Patient Suffering From Inflammatory Bowel Disease
The QUESAM study aims to translate into French and validate the traduction of 2 screening questionnaires for spondylo-arthritis among people with inflammatory bowel disease.
- Conditions
- Spondylarthritis, Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis
- Trial name
- QUESAM (NCT06998316)
- Testing
- Screening questionnaire
- Where
- France
- Volunteers
- 220 people
- Sponsor
- University Hospital, Grenoble
Crohn's Disease, Ulcerative Colitis
Dysmenorrhea in Women With Crohn's Disease and Ulcerative Colitis
This case-control study will screen for dysmenorrhea and assess severity of menstrual symptoms in menstruating women with CD and UC compared with healthy age-matched controls.
- Trial name
- NCT02274714
- Testing
- Questionnaire Only
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Ulcerative Colitis
Fecal Transplantation Using a Diet for Donor and Recipient in Refractory Colitis
Changing the microbiota has become the most intriguing target for intervention in inflammatory bowel disease (IBD). Dietary therapy is successful in mild to moderate Crohn's disease and may be effective in mild to moderate…
- Trial name
- NCT02734589
- Testing
- Fecal transplantation, Unique novel Diet for UC and Unique novel Diet for the donor + FMT, Unique novel Diet for UC
- Where
- 5 sites in France, Israel and 1 more
- Volunteers
- 54 people
- Sponsor
- Wolfson Medical Center
Colonic Neoplasms, Crohn Disease
Comparison of Intracorporeal and Extracorporeal Anastomoses for Minimally Invasive Right Colectomy
The primary objective of this study is to retrospectively compare the perioperative and short-term (discharge through 30 days) outcomes of intracorporeal and extracorporeal anastomosis in minimally invasive right colectomies for…
- Trial name
- NCT03019016
- Testing
- Right Colectomy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Intuitive Surgical
Inflammatory Bowel Disease, Crohn's Disease
Impact of Telemonitoring in the Management of Complex IBD in Spain: M-TECCU
M-TECCU is a study: multicenter, randomized and open. It consists of two parallel groups to compare the efficacy of the TECCU web-based telemonitoring system to achieve and maintain activity remission in patients with…
- Conditions
- Inflammatory Bowel Disease, Crohn's Disease, Ulcerative Colitis, Telemedicine
- Trial name
- M-TECCU (NCT06031038)
- Testing
- TECCU Software
- Where
- 30 sites in Spain
- Volunteers
- 290 people
- Sponsor
- Grupo Espanol de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa
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