Clinical trials: IBS
Irritable Bowel Syndrome
Fecal Amino Acids，Gut Taste Receptors and Irritable Bowel Syndromes
Clinical data, fresh feces and intestinal mucosal tissues of patients with diarrheal IBS were collected. High performance liquid chromatography, immunohistochemistry and immunofluorescence were used to study the amino acid levels…
- Trial name
- NCT06489444
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Endometriosis, Irritable Bowel Syndrome
Dietary Treatment of Endometriosis-related Irritable Bowel Syndrome
Many patients with endometriosis experience extra genital and abdominal symptoms as a major part of their problem. This includes gastrointestinal dysfunction with pain, urinary symptoms compatible with interstitial cystitis and…
- Conditions
- Endometriosis, Irritable Bowel Syndrome, Visceral Syndrome, Visceral Hypersensitivity
- Trial name
- NCT02924493
- Testing
- Diet low in fermentable carbohydrates (low FODMAP diet)
- Where
- Denmark
- Volunteers
- 22 people
- Sponsor
- University of Aarhus
Women With IBS-C
A Single-centre, Randomised, Double-blind, Controlled, Parallel-group Study to Evaluate the Effect of a Fermented Dairy Product on Abdominal Distension, Digestive Symptoms and Rectal Sensitivity in Patients With Irritable Bowel Syndrome With Constipation (IBS-C)
The purpose of this study is to evaluate the effect of a commercially available fermented dairy product containing probiotics (4 weeks, twice a day) on abdominal distension in IBS patients with constipation (IBS-C).
- Trial name
- NCT01097993
- Testing
- 1-fermented dairy product, 2- milk-based non-fermented dairy product (control product)
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Diarrhea-predominant Irritable Bowel Syndrome
Serum-Derived Bovine Immunoglobulin /Protein Isolate (SBI) 5.0 g Bid on Nutritional Status in Subjects With IBS-D
To evaluate the safety and effectiveness of oral nutritional therapy Serum-Derived Bovine Immunoglobulin (SBI) on nutritional status, epithelial barrier function, and mucosal expression of pivotal genes including tight junction…
- Trial name
- NCT02163213
- Testing
- Serum-derived bovine immunoglobulin protein isolate (SBI)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Mayo Clinic
Irritable Bowel Syndrome
Study to Evaluate the Role of Itopride HCI in Patients With Irritable Bowel Syndrome With Predominant Constipation
Patients suffering from Irritable Bowel Syndrome with predominant constipation will be provided with the study medication. The study medication will be evaluated for its efficacy in relieving the symptoms
- Trial name
- NCT01027260
- Testing
- Itopride HCI 50 mg, Itopride HCI 100 mg
- Where
- 4 sites in Pakistan
- Volunteers
- 268 people
- Sponsor
- Abbott
Irritable Bowel Syndrome, Fibromyalgia
Clinical Trial Examining Effects of Monosodium Glutamate (MSG) on Irritable Bowel Syndrome (IBS) and Fibromyalgia (FM)
Objective: Randomized, double blind, placebo-controlled, crossover, clinical trial to examine the effects of the food additive glutamate (in the form of MSG) on IBS and fibromyalgia.
- Trial name
- NCT00829218
- Testing
- Glutamate additive-free diet
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Oregon Health and Science University
Irritable Bowel Syndrome With Constipation (IBS-C)
A Study of the Effect of SYN-010 on Subjects With IBS-C
A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Multi-Dose Study of the Effect of Two Dosage Strengths of SYN-010 Compared with Placebo on Breath Methane Production in Breath Methane-Positive Subjects with…
- Trial name
- NCT02495623
- Testing
- SYN-010 21 mg, SYN-010 42 mg
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Theriva Biologics, Inc.
IBS - Irritable Bowel Syndrome, Diarrhea
Novel Pilot Study to Treat Symptoms of IBS With Diarrhea Using Combination Therapy of a Low-FODMAP Diet and a Neuromodulator
The purpose of this research is to study the added benefit of treating IBS symptoms with a medication called mirtazapine in treating IBS symptoms when paired with a low-FODMAP diet compared to a low-FODMAP diet alone.
- Trial name
- NCT06684470
- Testing
- Mirtazapine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Diarrhea-predominant Irritable Bowel Syndrome, Functional Diarrhea
Acupuncture for Patients With Diarrhea-predominant IBS or Functional Diarrhea: a Randomized Controlled Trial
This trial is to assess the effectiveness of three types of acupuncture for patients with functional diarrhea comparing to a positive drug control.
- Trial name
- NCT01350570
- Testing
- acupuncture, acupuncture group2, acupuncture group3
- Where
- China
- Volunteers
- 449 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Inflammatory Bowel Diseases
Use of Autologous, Adult Adipose-Derived Stem/Stromal Cells in Inflammatory Bowel Disease
Inflammatory Bowel Disease (IBD) is a group of inflammatory conditions of the small bowel and colon. Main types include Ulcerative Colitis and Crohn's Disease.
- Trial name
- ADcSVF-IBD (NCT02952131)
- Testing
- Lipoaspiration, AD-cSVF, Normal Saline IV
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Healeon Medical Inc
Irritable Bowel Syndrome (IBS)
Microbe-Gut Interaction in Microscopic Colitis and Post-Infectious Irritable Bowel Syndrome (IBS)
Objective: This study aims elucidate the pathophysiological link between the environment in the colon (mainly the microbiota), the local immune system and activation of the enteric nervous system in patients with post-infectious…
- Trial name
- NCT01787253
- Where
- Sweden
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
IBS - Irritable Bowel Syndrome
Ashtangayoga for IBS Show Positive Preliminary Effects on Symptoms and Well-being
The study aims to test the effect of Ashtanga yoga on well-being in patients with irritable bowel syndrome (IBS). The intervention comprises group sessions on the Ashtanga school of yoga.
- Trial name
- NCT04946604
- Testing
- Ashtangayoga
- Where
- Sweden
- Volunteers
- 14 people
- Sponsor
- Karolinska Institutet
IBS - Irritable Bowel Syndrome
Online, Gut-directed Hypnotherapy for Patients With Irritable Bowel Syndrome (IBS)
Adult IBS patients with symptoms refractory to standard medical treatment will receive online nurse-administered, gut-directed hypnotherapy in groups. The primary outcome measure was change in gastro-intestinal symptom severity.
- Trial name
- NCT06297785
- Testing
- Gut-directed hypnotherapy
- Where
- 2 sites in Sweden
- Volunteers
- 50 people
- Sponsor
- Sahlgrenska University Hospital
Irritable Bowel Syndrome With Diarrhea (IBS-D)
A Study of MD-7246 to Treat Abdominal Pain in Patients With Diarrhea-predominant Irritable Bowel Syndrome
To evaluate the safety and tolerability, treatment effect on abdominal pain, and dose response of MD-7246 administered orally to patients with diarrhea-predominant irritable bowel syndrome (IBS-D).
- Trial name
- NCT03931785
- Testing
- MD-7246
- Where
- 80 sites in United States
- Volunteers
- 515 people
- Sponsor
- Ironwood Pharmaceuticals, Inc.
Irritable Bowel Syndrome With Diarrhea
To Compare the Efficacy of Drugs in Combination for Treating Irritable Bowel Syndrome Associated With Diarrhea
The goal of this clinical trial is to compare the efficacy of four different drugs in combination for management of irritable bowel syndrome (IBS)-associated diarrhea.
- Trial name
- NCT05867550
- Testing
- Rifaximin 550 MG, Mebeverine 135 MG, Psyllium Husk
- Where
- Pakistan
- Volunteers
- 162 people
- Sponsor
- Bahria University
Irritable Bowel Syndrome
Mesalazine Treatment in IBS (The MIBS Study)
Irritable bowel syndrome (IBS) is a condition characterised by abdominal pain or discomfort in combination with altered bowel function (stool frequency and/or stool consistency), currently defined by the Rome III criteria.
- Trial name
- MIBS (NCT01699438)
- Testing
- Mesalazine
- Where
- 3 sites in Sweden
- Volunteers
- 211 people
- Sponsor
- Hans Törnblom
Asthma, Atrial Fibrillation
The Living With a Long-Term Condition Study
Psychological distress (anxiety and depression) is common in and experienced differently by people living with long-term health conditions (LTCs).
- Conditions
- Asthma, Atrial Fibrillation, Cancer, Cerebrovascular Disorders
- Trial name
- LTC (NCT06072287)
- Testing
- Living with LTC Questionnaire
- Where
- United Kingdom
- Volunteers
- 600 people
- Sponsor
- King's College London
IBS-C and IBS With Mixed Bowel Habits
Efficacy of Tegaserod in Relieving the Symptoms of Female Patients With Irritable Bowel Syndrome (IBS), Excluding Those With Predominant Diarrhea IBS
Recent literature has demonstrated that the group of IBS sufferers who experience mixed bowel habits may be more similar to IBS-C patients than IBS-D patients.
- Trial name
- NCT00142987
- Testing
- Tegaserod
- Volunteers
- 664 people
- Sponsor
- Novartis
Metabolic Syndrome, IBS - Irritable Bowel Syndrome
Applications of a Functional Dairy Product in Diet Therapy
The aim of the study will be to evaluate the effectiveness of dietary therapy using a functional dairy product, using fermented milk with selected probiotic cultures, in individuals with irritable bowel syndrome and metabolic…
- Trial name
- SUPRIMDIET (NCT07793487)
- Testing
- new functional milk drink, conventional, acidified milk drink
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Warsaw University of Life Sciences
Irritable Bowel Syndrome (IBS)
Probiotics and Biomarkers in Irritable Bowel Syndrome
The goal of this double-blind parallel-arm randomized controlled trial is to learn if a probiotic supplement (containing a new strain derived from L.
- Trial name
- BIO-IBS (NCT07584278)
- Testing
- Probiotic Supplementation (Lactobacillus Reuteri)
- Where
- Sweden
- Volunteers
- 252 people
- Sponsor
- Sahlgrenska University Hospital