Clinical trials: IBS - Irritable Bowel Syndrome
IBS - Irritable Bowel Syndrome
Effect of Postbiotic Product on Colonic Barriers in IBS
Impaired intestinal permeability and microbial dysbiosis are important pathophysiological mechanisms underlying irritable bowel syndrome (IBS).
- Trial name
- NCT05475314
- Testing
- ReFerm(R)
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Nordisk Rebalance A/S
Irritable Bowel Syndrome, Diarrhea
Fecal Microbiota Transplantation for IBS
The purpose of this study is to learn the efficacy and safety of fecal microbiota transplantation (FMT) using stool from a donor with low proteolytic activity and containing the bacteria Alistipes putredinis in patients with…
- Trial name
- NCT05776914
- Testing
- Donor Fecal Microbiota Transplantation, Autologous Fecal Microbiota Transplantation
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Madhusudan (Madhu) Grover, MBBS
IBS - Irritable Bowel Syndrome
Innovative Tools to Produce Legume-based Foods for Increased Consumer Acceptance
The aim of this study is to investigate the effects of enzymatic treatment to reduce GOS (galactooligosaccharides) in legume-based crackers in IBS (irritable bowel syndrome) persons.
- Trial name
- LeguComf (NCT05118243)
- Testing
- Control cracker, Enzyme-treated cracker
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- University of Helsinki
Irritable Bowel Syndrome
A Well-Being Intervention for People With IBS
The purpose of this randomized behavioral clinical trial is to examine whether a well-being intervention can improve both psychological well-being and physical outcomes in adults with Irritable Bowel Syndrome (IBS).
- Trial name
- NCT07600047
- Testing
- Well-Being Intervention
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Wisconsin, Madison
IBS - Irritable Bowel Syndrome, General Population
International Psychometric Validation Study of the Intestinal Gas Questionnaire (IGQ)
Objective: To confirm the psychometrics properties of the Intestinal Gas Questionnaire (IGQ) in subjects with Irritable Bowel Syndrome (IBS) diagnosis and General population both complaining of Gas-Related Symptoms (GRS).
- Trial name
- PRoVING (NCT03002584)
- Testing
- completion of self-reported questionnaires
- Where
- 5 sites in France, Spain and 1 more
- Volunteers
- 300 people
- Sponsor
- University Paris 7 - Denis Diderot
Irritable Bowel Syndrome With Diarrhea
Efficacy Study of Rezular (Arverapamil) in the Treatment of Irritable Bowel Syndrome With Diarrhea (IBS-D)
The purpose of the study is to determine the efficacy and safety of Rezular (arverapamil) in the treatment of IBS-D.
- Trial name
- ARDIS-1 (NCT00552565)
- Testing
- Rezular 15mg, Rezular
- Where
- United States
- Volunteers
- 711 people
- Sponsor
- AGI Therapeutics, Inc.
Irritable Bowel Syndrome With Diarrhea
12-Week Efficacy and Safety Study of Ibodutant in Women With Irritable Bowel Syndrome With Diarrhea (IBS-D)
Irritable Bowel Syndrome with diarrhoea (IBS-D) is a functional gastrointestinal disorder characterised by chronic or recurrent abdominal pain or discomfort and diarrhoea.
- Trial name
- IRIS-05 (NCT02320318)
- Testing
- Ibodutant 10 mg
- Where
- 20 sites in Singapore, South Korea and 1 more
- Sponsor
- Menarini Group
Irritable Bowel Syndrome (IBS)
New Microbiota-endocrine Axis in Fructose Malabsorption-caused Visceral Hypersensitivity in Irritable Bowel Syndrome.
Irritable bowel syndrome (IBS) affects around 4% of the general population and remains the most common functional bowel disorder.
- Trial name
- ENDOLORII (NCT07337707)
- Testing
- urine intestinal permeability test or lactulose/mannitol test, Blood test, food diary
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Rouen
IBS (Irritable Bowel Syndrome), IBD (Inflammatory Bowel Disease)
Efficacy of PosBion® Postbiotic Supplementation in Adults With Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder characterized by recurrent abdominal pain and altered bowel habits, often associated with impaired intestinal barrier function, low-grade…
- Conditions
- IBS (Irritable Bowel Syndrome), IBD (Inflammatory Bowel Disease), Gut Health
- Trial name
- NCT07699926
- Testing
- Postbiotic supplementation
- Where
- Malaysia
- Volunteers
- 55 people
- Sponsor
- My Myracle Sdn.Bhd
Irritable Bowel Syndrome, Panic Disorder
Escitalopram Trial for Irritable Bowel Syndrome (IBS) Patients With Panic Disorder
This study will be executed according to a randomized double-blind placebo-controlled trial with two parallel groups, treated over the period of 6 months with escitalopram or placebo.
- Trial name
- NCT01551225
- Testing
- Escitalopram
- Where
- Netherlands
- Volunteers
- 32 people
- Sponsor
- Maastricht University Medical Center
Irritable Bowel Syndrome
Effectiveness of On-demand Meteospasmyl® Use in Irritable Bowel Syndrome (IBS)
The purpose of this study is to compare the effectiveness of 2 IBS treatment strategies: Strategy A = MeteoSpasmyl®, on-demand therapy Strategy B = standard of care chosen by the physician
- Trial name
- NCT01404923
- Testing
- anti spasmodic agents, alverine citrate, simeticone
- Volunteers
- 436 people
- Sponsor
- Laboratoires Mayoly Spindler
Irritable Bowel Syndrome, Obesity
Moderate Continuous Versus High Interval Intensity Training on Gut Dysbiosis and GLP1 Hormone in IBS
investigating the response of gut bacteria via measuring short chain fatty acids and Glucagon like peptide hormone to two different modes of exercises in pre-diabetic, obese patients with irritable bowel syndrome.
- Conditions
- Irritable Bowel Syndrome, Obesity, Dysbiosis
- Trial name
- NCT06408610
- Testing
- moderate intensity continuous training
- Where
- 2 sites in Egypt
- Volunteers
- 66 people
- Sponsor
- Cairo University
Food Intolerance Syndromes, Small Intestinal Bacterial Overgrowth Syndrome (SIBO)
Combined Lactulose H2-breath Test With Abdominal Imaging
Hydrogen (H₂) breath tests serve several purposes. (i) detect malabsorption of carbohydrates such as lactose and fructose, (ii) measurement of oro-caecal transit time (iii) associate hydrogen production with the onset of…
- Conditions
- Food Intolerance Syndromes, Small Intestinal Bacterial Overgrowth Syndrome (SIBO), Breath Tests
- Trial name
- NCT07145580
- Where
- Switzerland
- Volunteers
- 510 people
- Sponsor
- Klinik Arlesheim
ME/CFS, IBS - Irritable Bowel Syndrome
The Use of Directed Probiotics in ME/CFS: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
This clinical study aims to evaluate the use of i3.1 probiotic in participants who meet the Institute of Medicine (Canadian Consensus Criteria) case definition for ME/CFS and who may or may not be diagnosed with irritable bowel…
- Trial name
- NCT06211062
- Testing
- Floradapt Intensive GI
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Nova Southeastern University
IBS - Irritable Bowel Syndrome
Ayurvedic Nutritional Counseling for Patients With IBS in Comparison to Conventional Nutritional Counseling
The main goal of this randomized controlled clinical study is to evaluate the efficacy of an individual Ayurvedic nutritional counseling (according to tradition) compared to an individual conventional dietary advice (according to…
- Trial name
- AYURDA (NCT03019861)
- Testing
- Ayurvedic nutritional counseling, Conventional nutritional counseling
- Where
- 2 sites in Germany
- Volunteers
- 69 people
- Sponsor
- Charite University, Berlin, Germany
Diarrhea-predominant Irritable Bowel Syndrome
Rifamycin SV-MMX® 600 mg Tablets Administered Three or Two Times Daily to Patients With IBS-D
The objective of this study is to evaluate the safety and efficacy Rifamycin SV-MMX® 600 mg tablets for patients with diarrhoea-predominant irritable bowel syndrome when administered two to three times daily.
- Trial name
- NCT03099785
- Testing
- Rifamycin SV 600mg t.i.d.
- Where
- 29 sites in Belgium, Germany and 2 more
- Volunteers
- 279 people
- Sponsor
- Cosmo Technologies Ltd
IBS - Irritable Bowel Syndrome
Implementing a Low FODMAP Diet in Irritable Bowel Syndrome Patients
Researchers are trying to determine the best course of action regarding the dietary management with a diet low in fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP diet) for irritable bowel syndrome.
- Trial name
- NCT03948854
- Testing
- Registered dietitian, On-line video program, Printed handout
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Mayo Clinic
Irritable Colon, Irritable Bowel Syndrome (IBS)
Study On The Effect Of GW876008 On Cerebral Blood Flow In Irritable Bowel Syndrome (IBS) Patients And Healthy Volunteers
This is a three-period crossover study to compare GW876008 and placebo to see if GW876008 will normalise blood flow responses after different emotional stimuli.
- Trial name
- NCT00376896
- Testing
- GW876008 200mcg, GW876008 20mcg
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline