Clinical trials: ICD Malfunction
Congestive Heart Failure, Cardiac Resynchronization Therapy
Improvement in Clinical Outcomes in Heart Failure Patients With ICDs That Practice Meditation
This is a trial to examine the effects of meditation on the incidence of ventricular arrhythmias and the psychological profiles in patients with implanted cardiac defibrillators. We wish to test the following hypotheses: 1.
- Trial name
- NCT00611260
- Testing
- Vipassana Meditation practice and instruction, Standard Medical Care
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of California, Davis
Heart Failure, Arrhythmias, Cardiac
Heart Failure and Sudden Cardiac Death Japan Registry
The purpose of this observational registry is to collect clinical events and outcome data in 4 different study populations (cohorts), with a majority of Japanese subjects, that are at risk of sudden cardiac death (SCD) and heart…
- Conditions
- Heart Failure, Arrhythmias, Cardiac, Sudden Cardiac Death
- Trial name
- HINODE (NCT03185832)
- Testing
- CRT-D, ICD, PM / CRT-P
- Where
- 34 sites in Japan
- Volunteers
- 354 people
- Sponsor
- Boston Scientific Corporation
Heart Failure With Reduced Ejection Fraction, Ventricular Arrhythmia
Circulating RNA Markers of Ventricular Arrhythmias in Remotely Monitored Patients With Post-Infarction Heart Failure and Implanted Cardioverter-Defibrillators
This prospective observational study evaluates whether circulating small non-coding RNAs, particularly microRNAs, are associated with ventricular arrhythmias in patients with post-myocardial infarction heart failure who have an…
- Conditions
- Heart Failure With Reduced Ejection Fraction, Ventricular Arrhythmia, Ischemic Cardiomyopathy
- Trial name
- NCT07795892
- Testing
- Circulating Small RNA Profiling
- Where
- Poland
- Volunteers
- 57 people
- Sponsor
- University of Rzeszow
Bundle-Branch Block, Left, Cardiac Failure
Prognosis of Patients With Compete Left Bundle Branch Block
The investigators sought to evaluate the morphological and functional changes, risk stratification and prognosis of patients of participants with compete left bundle branch block (CLBBB).
- Conditions
- Bundle-Branch Block, Left, Cardiac Failure, ICD/Pacemaker Implantation, Cardiovascular Magnetic Resonance Imaging
- Trial name
- NCT03096678
- Testing
- Cardiac Magnetic Resonance Imaging
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
ICD, ICD Malfunction
Multicenter Subcutaneous ICD Registry
This multicenter registry aims to collect data regarding S-ICD longevity, and battery and lead failure rates. Only clinically collected data is gathered in this registry.
- Trial name
- NCT04767516
- Testing
- no intervention
- Where
- Germany
- Volunteers
- 1,300 people
- Sponsor
- Universitätsklinikum Köln
Congestive Heart Failure, Cardiac Resynchronization Therapy
TRIAGE-CRT Telemonitoring in Patients With CHF and Indication of CRT-D
This feasibility study will investigate the clinical benefit of the combined use of BIOTRONIK Home Monitoring (HM) and weight and blood pressure (BP) external telemonitoring (ETM) in the follow-up treatment of patients implanted…
- Trial name
- NCT00395642
- Testing
- Kronos LV-T, Lumax HF-T
- Where
- 12 sites in United States
- Volunteers
- 66 people
- Sponsor
- Biotronik, Inc.
Disorder of Cardiac Pacemaker System, Disorder of Implantable Defibrillator
Examination of Implant´s Safety in an Electronic and Magnetic Field Environment
The number of active electrical cardiac implants such as internal cardioverter defibrillators (ICDs), pacemakers or cardiac contractility modules (CCM) has significantly risen over the last two decades.
- Conditions
- Disorder of Cardiac Pacemaker System, Disorder of Implantable Defibrillator, Cardiac Arrhythmia
- Trial name
- FEMU (NCT01626261)
- Testing
- Magnetic and electric field´s impact on the implant
- Where
- Germany
- Volunteers
- 281 people
- Sponsor
- RWTH Aachen University
Implantable Defibrillator Lead Dysfunction, Implantable Automatic Defibrillator Malfunction
Shock Testing to Unmask RV Lead and GEnerator Malfunction in ICD Patients: the SURGE-ICD Registry
Shock testing during ICD generator replacement has been omitted by many centers. A previous study revealed lead failures in internally cardioverted patients with previously normal HV-lead values.
- Conditions
- Implantable Defibrillator Lead Dysfunction, Implantable Automatic Defibrillator Malfunction, Implantable Defibrillator User
- Trial name
- Surge-ICD (NCT04858672)
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- Universitätsklinikum Köln
Sleep Apnea, Sudden Cardiac Death
European Sleep Apnea and Sudden CArdiac Death ProjEct
The objective of ESCAPE-SCD Study is assessment of the effect of sleep apnea on sudden cardiac death risk and cardiovascular outcomes in patients with ischemic cardiomyopathy.
- Conditions
- Sleep Apnea, Sudden Cardiac Death, Heart Failure, Ischemic Cardiomyopathy
- Trial name
- ESCAPE-SCD (NCT02506166)
- Testing
- Positive Airway Pressure Therapy
- Volunteers
- 900 people
- Sponsor
- University Hospital Olomouc
Heart Failure, Systolic
Cardiac Magnetic Resonance Imaging After Cardiac Resynchronization Therapy
This study is evaluating how MRI after CRT can provide key insights regarding LV function, structure, and mechanics resulting from CRT in patients with or without LV scar and inform optimal pacing strategies.
- Trial name
- NCT03183011
- Testing
- MRI
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Kenneth Bilchick, MD
Prosthesis-Related Infections, Equipment Failure
Medico-economic Evaluation of Strategies for the Lead Extraction of Implantable Defibrillator and Pacemakers
The growing use and the expanding indications for cardiovascular implantable electronic devices (CIEDs) have been associated to an increase of device removal.
- Conditions
- Prosthesis-Related Infections, Equipment Failure, Heart Failure, Arrhythmias
- Trial name
- GAINE LASER (NCT03121183)
- Testing
- Laser sheath, Implantable Cardiac Device lead extraction
- Where
- France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Clermont-Ferrand
Heart Failure, Arrythmia
Remote Monitoring To Identify Worsening Heart Failure The REMOTI-HF Randomized Clinical Trial
Heart failure, characterized by high mortality and morbidity rates, frequent hospital admissions, and prolonged stays in cardiology wards, significantly impacts patients' quality of life.
- Trial name
- REMOTI-HF (NCT06422832)
- Testing
- HeartLogic or TriageHF Algorithms for implantable devices
- Volunteers
- 270 people
- Sponsor
- Unidade Local de Saúde de Coimbra, EPE
Heart Failure, Ventricular Dysfunction
B-Left HF: Biventricular Versus Left Univentricular Pacing With Implantable Cardiac Defibrillator (ICD) Back-Up in Heart Failure Patients
The purpose of this study is to demonstrate that biventricular pacing (BiV) and left univentricular (left ventricular [LV] only) pacing are safe and effective for cardiac resynchronization therapy in heart failure patients…
- Conditions
- Heart Failure, Ventricular Dysfunction, Heart Diseases
- Trial name
- NCT00187213
- Testing
- Cardiac Resynchronization Therapy
- Where
- France
- Sponsor
- Abbott Medical Devices
Heart Failure, Death, Sudden, Cardiac
Sympathetic Nerve Activity and an Implantable Cardioverter Defibrillator in Heart Failure Patients
The aim of this study is to analyze whether the sympathetic tone, measured indirectly and directly by muscle sympathetic nerve activity recording, is elevated in patients with heart failure receiving an appropriate shock from…
- Trial name
- NCT00439790
- Testing
- Microneurography
- Where
- France
- Volunteers
- 109 people
- Sponsor
- University Hospital, Toulouse
Severe Cardiac Insufficiency
Determination of Risk Factors of Ventricular Arrhythmias (VAs) After Implantation of Continuous Flow Left Ventricular Assist Device With Continuous Flow Left Ventricular Assist Device (CF-LVAD)
Determination of risk factors of ventricular arrhythmias (VAs) after implantation of continuous flow left ventricular assist device in order to characterize which patient requires ICD implantation in primary prevention.
- Trial name
- ASSIST-ICD (NCT02873169)
- Testing
- Implantable cardioverter-defibrillator
- Where
- 20 sites in France
- Volunteers
- 681 people
- Sponsor
- Rennes University Hospital
Chagas Cardiomyopathy, Speckle Tracking Echocardiography
Cardiac Mechanics by Speckle Tracking as a Prognostic Predictor in Patients With Chagas Cardiomyopathy
This study aims to evaluate the prognostic value of myocardial mechanics parameters, including global longitudinal strain (GLS) and mechanical dispersion (MD), assessed through speckle tracking echocardiography, in patients with…
- Conditions
- Chagas Cardiomyopathy, Speckle Tracking Echocardiography, Arrythmias, Sudden Death
- Trial name
- ST-Chagas (NCT06806722)
- Where
- Brazil
- Volunteers
- 153 people
- Sponsor
- University of Sao Paulo
Heart Failure, Congestive
X-Change HF - Exchange of the Existing Pacemaker/ICD in Bradycardia Patients Suffering From Heart Failure
The goal of X-Change HF is to estimate the effect of biventricular stimulation in patients who need antibradycardia ventricular stimulation (more than 80%); are eligible for the exchange of an old pacemaker or implantable…
- Trial name
- NCT00157846
- Testing
- CRT-P or CRT-D Device
- Where
- 10 sites in Germany
- Volunteers
- 36 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Small Cell Lung Cancer Extensive Stage
SHR-1210 Combined With Epirubicin in the Treatment of Extensive Disease Small Cell Lung Cancer
Patients with extensive disease SCLC after failure of first-line treatment were enrolled with SHR-1210 and epirubicin for 3 cycles to evaluate initial efficacy
- Trial name
- NCT03755115
- Testing
- Epirubicin plus SHR1210
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Henan Cancer Hospital
Congestive Heart Failure
EnSite NavX-Guided Coronary Sinus Mapping During CRT Implant
Use of the EnSite NavX system to map the coronary vasculature during CRT implant
- Trial name
- Bi-VNavX (NCT01615835)
- Testing
- EnSite NavX System
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- Abbott Medical Devices
Heart Disease
Managed Ventricular Pacing ("MVP") Trial
The purpose of the study is to compare two device settings (sets of instructions) used by the ICD. The Implantable Cardiac Defibrillator ("ICD") can be set to use one wire (top or bottom of the heart) or two wires (top and…
- Trial name
- MVP (NCT00281099)
- Testing
- ICD (Implantable Cardioverter Defibrillator)
- Where
- 73 sites in United States, Austria and 10 more
- Volunteers
- 1,031 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure