Clinical trials: ICH - Intracerebral Hemorrhage
Post Cerebral Hemorrhage
Seizures Post Intracerebral Hemorrhage
This study examines early antiepileptic treatment with valproic acid for acute cerebral hemorrhage against a placebo group immediately post event to evaluate the outcome of these patients regarding seizures and neurological…
- Trial name
- NCT01115959
- Testing
- valproic acid
- Volunteers
- 72 people
- Sponsor
- Wolfson Medical Center
Intracerebral Haemorrhage (ICH)
Surgical Evacuation Of Spontaneous Intracerebral Hematoma: Clinical Outcomes and Prognostic Factors
The aim of this study is to assess the safety and efficacy of surgical evacuation of spontaneous intracerebral hemorrhage.
- Trial name
- NCT06816641
- Testing
- Surgical Evacuation of Intracerebral Hemorrhage
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sohag University
Spontaneous Intracerebral Hemorrhage
Risk Stratification and Minimally Invasive Surgery in Acute ICH Patients
The study consists of 2 parts: the first part is to conduct a multicenter retrospective analysis of more than 1000 acute ICH patients treated by conservative observation from 33 centers in China to create a predictive model of…
- Trial name
- Risa-MIS-ICH (NCT03862729)
- Testing
- Minimally invasive surgery, conventional treatment
- Where
- China
- Volunteers
- 1,300 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Cerebral Cavernous Malformation, Intracerebral Hemorrhage
CoHOrt of Cerebral CavernOus maLformATion: multicEnter Prospective Observational Study
The aim of this prospective study is to reveal the natural history of symptomatic hemorrhage in adult patients with cerebral cavernous malformation with the goal of informing the treatment plan.
- Trial name
- CHOCOOATE (NCT02946866)
- Where
- 8 sites in South Korea
- Volunteers
- 228 people
- Sponsor
- Seoul National University Hospital
Hypertensive Intracerebral Hemorrhage, Intraventricular Hemorrhage
Neuroinflammatory Response in Patients With ICH and IVH Treated With rtPA
This study compares the neuroinflammatory response in patients with hypertensive ICH associated with IVH treated with intraventriculary applied rtPA, and the control group.
- Conditions
- Hypertensive Intracerebral Hemorrhage, Intraventricular Hemorrhage, Brain Injuries
- Trial name
- NCT03452722
- Testing
- intraventricual recombinant tissue plasminogen activator application
- Volunteers
- 88 people
- Sponsor
- University of Rijeka
Stroke
Biomarkers Based EArly Diagnosis of STroke Subtype Cohort（Bio-EAST）
Intracerebral hemorrhage carries high rates of mortality and disability, imposes a significant societal burden. Based on findings from our previous multicenter randomized controlled clinical trial (INTERACT4), we revealed that…
- Trial name
- Bio-EAST (NCT07003477)
- Testing
- Detection of peripheral blood biomarkers
- Where
- China
- Volunteers
- 527 people
- Sponsor
- Shanghai East Hospital
Intracerebral Hemorrhage
Prospective Cohort Study of Intracerebral Hemorrhage
The investigators design a prospective, observational cohort study to provide contemporary information on the prevalence, characteristics, risk stratification，cost-effective ,treatments and prognosis of Chinese hospitalised adult…
- Trial name
- POSTER (NCT04707105)
- Where
- China
- Volunteers
- 856 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Venous Thromboembolism, Pulmonary Embolism
Timing of Venous Thromboembolism Prophylaxis in Patients With Hypertensive Intracerebral Hemorrhage
The objective of this randomized clinical trial is to evaluate the safety and efficiency of different anticoagulation schemes with heparin for venous thromboembolism prevention in patients with hypertensive intracerebral…
- Conditions
- Venous Thromboembolism, Pulmonary Embolism, Intracerebral Hemorrhage, Deep Vein Thrombosis
- Trial name
- NCT06753786
- Testing
- Venous thromboembolism prophylaxis with unfractionated heparin or low molecular weight heparin starting within the first 2 days but not earlier than 12 hours after a hospital admission., Venous thromboembolism prophylaxis with unfractionated heparin or low molecular weight heparin starting on the 3rd day after a hospital admission.
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Pirogov Russian National Research Medical University
Treatment of Spontaneous Intracerebral Hemorrhage
Safety and Efficacy of Stereotactic Aspiration Plus Urokinase in Deep Intracerebral Hemorrhage Evacuation
This is a nationwide, multicenter, open-label, randomized controlled trial of early minimally invasive treatment for deep-seated spontaneous cerebral hemorrhage (dICH).
- Trial name
- STAPLE-dICH (NCT04686877)
- Testing
- STAPLE
- Where
- China
- Volunteers
- 400 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Severe Spontaneous Intracranial Hemorrhage, Long-term Antiplatelet Treatment
China Research for Severe Spontaneous Intracerebral Hemorrhage（CRISIH）
Background: Although emergency surgery may reduce mortality in patients with severe spontaneous intracerebral hemorrhage (SSICH), the effectiveness and safety of surgical treatment among SSICH patients receiving long-term oral…
- Conditions
- Severe Spontaneous Intracranial Hemorrhage, Long-term Antiplatelet Treatment, Emergency Surgery, Complications
- Trial name
- NCT05975398
- Testing
- Emergency neurosurgery, Conservative treatment
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Beijing Tiantan Hospital
Disorders of Consciousness, Spontaneous Intracerebral Hemorrhage
Transcutaneous Auricular Vagus Nerve Stimulation for Recovery of Consciousness After Surgery for Spontaneous Intracerebral Hemorrhage
Disorders of consciousness are common after surgery for severe spontaneous intracerebral hemorrhage and are associated with high mortality, disability, and long-term dependence.
- Trial name
- TAVNS-SICH (NCT07761507)
- Testing
- Active Transcutaneous Auricular Vagus Nerve Stimulation
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Beijing Tiantan Hospital
Atrial Fibrillation, Stroke
Prevention of Stroke by Left Atrial Appendage Closure in Atrial Fibrillation Patients After Intracerebral Hemorrhage
Intracerebral hemorrhage (ICH) in patients with non-valvular atrial fibrillation (NVAF) poses a particular dilemma for thromboprophylaxis.
- Conditions
- Atrial Fibrillation, Stroke, Intracerebral Hemorrhage
- Trial name
- NCT02830152
- Testing
- LAAO, Medical Therapy
- Where
- 17 sites in Denmark, Finland and 2 more
- Volunteers
- 750 people
- Sponsor
- Karolinska Institutet
Stroke, Vascular Accident
PROpranolol for Cerebral Hemorrhage-ASsociated pnEumonia (PRO-CHASE)
Stroke-associated pneumonia (SAP) is a grave complication of stroke and one of the most important predictors for patients' poor outcomes.
- Conditions
- Stroke, Vascular Accident, Intracranial Hemorrhages, Intracerebral Hemorrhage
- Trial name
- PRO-CHASE (NCT05419193)
- Testing
- Propranolol Hydrochloride, control group
- Where
- 12 sites in China
- Volunteers
- 168 people
- Sponsor
- Beijing Tiantan Hospital
Intra Cerebral Hemorrhage, ICH - Intracerebral Hemorrhage
REpeated ASSEssment of SurvivorS in Intracerebral Hemorrhage Study
The investigators propose to perform serial detailed cognitive, motor, behavioral, and blood collection follow-up using longitudinal structured telephone interviews of an anticipated 350 ICH survivors enrolled in Minimally…
- Conditions
- Intra Cerebral Hemorrhage, ICH - Intracerebral Hemorrhage, ICH, Hemorrhage
- Trial name
- ICH03 (NCT05611918)
- Where
- 26 sites in United States
- Volunteers
- 350 people
- Sponsor
- Johns Hopkins University
Ischemic Stroke, Intracerebral Hemorrhage
Evaluating the Safety and Efficacy of Telemedicine Neurology Assessments on a Mobile Stroke Unit
The goal of this clinical trial is to compare a telemedicine neurologist staffing model to a traditional on-board model in patients being assessed for suspected acute stroke on a mobile stroke unit.
- Trial name
- MSU-TELEMED (NCT05991310)
- Testing
- Telemedicine Assessment by Remote Neurologist, In-Person Assessment by an Onboard Neurologist
- Where
- Australia
- Volunteers
- 270 people
- Sponsor
- Melbourne Health
Intracerebral Hemorrhage
Evaluation of CN-105 in Subject With Acute Supratentorial Intracerebral Hemorrhage
Phase 2, randomized, double-blind, placebo controlled study to evaluate the administration of CN-105 in patients with supratentorial intracerebral hemorrhage (ICH).
- Trial name
- S-CATCH (NCT03711903)
- Testing
- Acetyl-Valine-Serine-Arginine-Arginine-Arginine-NH2 (Ac-VSRRR- NH2)., 0.9% Sodium-chloride
- Where
- Singapore
- Volunteers
- 60 people
- Sponsor
- National Neuroscience Institute
Subarachnoid Hemorrhage, Intracerebral Hemorrhage
Multimodal Neuromonitoring
Theoretical Framework \& Background Cortical spreading depressions (CSD) and seizures, are crucial in the development of delayed cerebral ischemia and poor functional outcome in patients suffering from acute brain injuries such…
- Conditions
- Subarachnoid Hemorrhage, Intracerebral Hemorrhage, Traumatic Brain Injury, Cortical Spreading Depolarization and Depression
- Trial name
- MMNM (NCT04737369)
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Medical University of Vienna
Stroke, Ischemic Stroke
Transitions of Care for Stroke Patients
For stroke patients, early initiation of therapy typically yields the best functional outcomes. Rehabilitation of stroke patients immediately after hospitalization minimizes deleterious effects of immobility and facilitates…
- Conditions
- Stroke, Ischemic Stroke, Intracerebral Hemorrhage
- Trial name
- NCT06011720
- Testing
- Improved transition of care.
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- Deviyani Mehta, MD
Delirium, Cognitive Impairment
Illuminating Neuropsychological Dysfunction and Systemic Inflammatory Mechanisms Gleaned After Hospitalization in Trauma-ICU Study
Cognitive skills are essential to live independently, manage finances, maintain employment, and function in society. Loss of these cognitive skills puts a tremendous burden on society as seen with dementias, Alzheimer's disease…
- Conditions
- Delirium, Cognitive Impairment, Alzheimer; Early Onset, Trauma
- Trial name
- INSIGHT-ICU (NCT03098459)
- Testing
- Non-interventional observational prospective cohort study
- Where
- United States
- Volunteers
- 432 people
- Sponsor
- Vanderbilt University Medical Center
Intraventricular Hemorrhage, Intracerebral Hemorrhage
The Natural History of Procalcitonin in Hemorrhagic Stroke
Approximately 12% of strokes in the United States are hemorrhagic.1 Hemorrhagic stroke can lead to multiple complications including fever that is not infectious.
- Trial name
- NCT01498705
- Testing
- Procalcitonin level
- Where
- United States
- Sponsor
- CAMC Health System