Clinical trials: ICH - Intracerebral Hemorrhage
Intracerebral Hemorrhage
TaVNS for Acute Intracerebral Hemorrhage
This study aims to evaluate the efficacy and safety of transcutaneous auricular vagus nerve stimulation (taVNS) in patients with acute intracerebral hemorrhage (ICH).
- Trial name
- TAVANS-ICH (NCT06918964)
- Testing
- transcutaneous auricular vagus nerve stimulation device
- Where
- China
- Volunteers
- 186 people
- Sponsor
- Beijing Tiantan Hospital
Trauma, Craniocerebral Trauma
Early Versus Late Intubation Trial in Physician Manned Emergency Medical Services
This study looks at advanced airway management in critically ill or injured patients treated by physician manned emergency medical services, comparing early (on-scene) intubation to late (emergency department) intubation.
- Conditions
- Trauma, Craniocerebral Trauma, Intracerebral Hemorrhage, Seizures
- Trial name
- ELITE (NCT01730001)
- Testing
- Early Intubation, Late intubation
- Where
- 2 sites in Norway
- Sponsor
- Norwegian Air Ambulance Foundation
Ischemic Stroke, Intracerebral Hemorrhage
Emergency Stroke Unit for Acute Cerebrovascular Events: A Prospective, Single-arm Trial With a Historical Control Group
Background Reperfusion therapies, i.e., intravenous thrombolysis (IVT) and/or endovascular thrombectomy (EVT), are most effective treatments in the management of acute ischemic stroke (AIS) patients.
- Conditions
- Ischemic Stroke, Intracerebral Hemorrhage, Stroke, Stroke, Acute
- Trial name
- ESU-ACE-E (NCT06728592)
- Testing
- Portable Magnetic Resonance Imaging
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Chinese University of Hong Kong
Stroke, Post-Stroke Cognitive Impairment
Immune-Inflammatory Biomarkers in Predicting Early Cognitive Impairment in Adults With Acute Basal Ganglionic Stroke
Post-stroke cognitive impairment (PSCI) is a common and disabling complication that affects memory, thinking, and daily functioning after a stroke.
- Conditions
- Stroke, Post-Stroke Cognitive Impairment, Ischemic Stroke, Intracerebral Hemorrhage
- Trial name
- NCT07837466
- Volunteers
- 100 people
- Sponsor
- Assiut University
Intracerebral Hemorrhage, Minimally Invasive Surgical Procedures
Dutch Intracerebral Hemorrhage Surgery Trial
Background: Intracerebral hemorrhage (ICH) accounts for 16-19% of all strokes in Western Europe and contributes profoundly to mortality and disability.
- Conditions
- Intracerebral Hemorrhage, Minimally Invasive Surgical Procedures, Endoscopic Surgical Procedures
- Trial name
- DIST (NCT05460793)
- Testing
- Minimally invasive endoscopy-guided surgery
- Where
- 11 sites in Netherlands
- Volunteers
- 600 people
- Sponsor
- Radboud University Medical Center
Intracranial Hemorrhage, Spontaneous
Prediction of Functional Recovery in Patients With Intracerebral Hemorrhage
Currently, we lack sufficiently reliable tools to accurately predict, in the first few hours, the vital prognosis, functional status, and quality of life of patients with intracerebral hemorrhage (ICH).
- Trial name
- PRO-ICH (NCT07728734)
- Testing
- CLINICAL SCORE TO PREDICT FUNCTIONAL OUTCOME, Variables necessary for calculating the score under study (PRO-ICH) will be collected, as well as baseline and 60-120 minutes after baseline of serum blood samples
- Where
- Spain
- Volunteers
- 1,688 people
- Sponsor
- Germans Trias i Pujol Hospital
Stroke
Long Term Outcome After Hemorrhagic Stroke Surgery
The investigators retrospectively reviewed all patients with neurosurgical operations for hemorrhagic stroke (intracerebral hemorrhage) between 1999 and 2008.
- Trial name
- NCT01409252
- Where
- China
- Volunteers
- 191 people
- Sponsor
- Chinese University of Hong Kong
Cerebral Amyloid Angiopathy
Cortical Superficial Siderosis and Risk of Recurrent Intracerebral Hemorrhage in Cerebral Amyloid Angiopathy.
Cerebral amyloid angiopathy (CAA) is a major cause of lobar intracerebral hemorrhage (ICH) in the elderly with high risk of recurrence.
- Trial name
- CORELIA (NCT03464344)
- Testing
- neurological, neuropsychological and MRI evaluation
- Where
- 4 sites in France
- Volunteers
- 170 people
- Sponsor
- University Hospital, Toulouse
Intracerebral Hemorrhage, Targeted Temperature Management
Targeted Temperature Management Via Bladder Monitoring in ICH
The goal of this clinical trial is to learn whether a bladder temperature monitoring-guided targeted temperature management (TTM) strategy improves functional recovery in patients with severe intracerebral hemorrhage, compared to…
- Trial name
- BTTM-ICH (NCT07302009)
- Testing
- Bladder Temperature Monitoring, Standard Temperature Monitoring Group
- Where
- China
- Volunteers
- 318 people
- Sponsor
- Yanyan Gong
Intracerebral Hemorrhage, Nontraumatic Intracerebral Hemorrhage
CIRP and Cathepsin B in Neuroinflammation After Intracerebral Hemorrhage
This is a single-center, investigator-initiated, prospective observational case-control study. Patients with intracerebral hemorrhage and healthy controls will be enrolled at Xuanwu Hospital, Capital Medical University.
- Trial name
- CIRP-ICH (NCT07665255)
- Testing
- Blood Sample Collection
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Intracerebral Hemorrhage
Simvastatin For Intracerebral Hemorrhage Study
Study Objective: To analyze if statins are effective in ameliorating perihematomal edema evolution thereby reducing mortality and improving functional outcomes following spontaneous intracerebral hemorrhage (ICH).
- Trial name
- NCT00718328
- Testing
- Simvastatin 80 mg
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Johns Hopkins University
Hypothermia, Primary Intracerebral Hemorrhage
Pilot Study of Hypothermia for Intracerebral Hemorrhage in Croatia
In this pilot study the researchers will investigate efficacy of hypothermia in the early stage of treatment patients with primary intracerebral hemorrhage.
- Conditions
- Hypothermia, Primary Intracerebral Hemorrhage, Signs and Symptoms
- Trial name
- NCT01221142
- Testing
- Cincinnati Sub-Zero," Blanketrol III"
- Where
- Croatia
- Volunteers
- 20 people
- Sponsor
- University of Rijeka
Hemorrhage, Intracranial, Outcome Measure
Clinical Characteristics and Outcome of Patients With Hemorrhagic Stroke Admitted in Neurology Department in a Tertiary Hospital
The main aim of this study is to know about the clinical profile of patients who are diagnosed as hemorrhagic stroke as well as the factors that affect good and bad outcomes of those patients after 3 months.
- Trial name
- NCT06824311
- Where
- Nepal
- Volunteers
- 197 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Nontraumatic Intracerebral Hemorrhage, Multiple Localized
Clevidipine (Cleviprex®) Compared With Urapidil (Ebrantil®)
Intracerebral hemorrhage (ICH) is responsible for 10-15% of primary strokes. ICH is a dynamic process with three phases: initial hemorrhage, followed by hematoma expansion and perihematoma edema formation.
- Trial name
- Clevidipine (NCT03300479)
- Testing
- Clevidipine, Urapidil
- Where
- Switzerland
- Sponsor
- University of Zurich
Spontaneous Intracerebral Hemorrhage
Early-Start Antiplatelet Treatment After Neurosurgery in Patients With Spontaneous Intracerebral Hemorrhage
This study is a multicenter, prospective, open-label, endpoint-blind, randomized controlled study.Patients receiving surgical treatment for SICH were divided into groups using the random machine method.
- Trial name
- NCT04820972
- Testing
- Antiplatelet Agents
- Where
- China
- Volunteers
- 269 people
- Sponsor
- Beijing Tiantan Hospital
Intracerebral Hemorrhage, Low T3 Syndrome
Efficacy of Thyroid Hormone Replacement for Secondary Hypothyroidism Following Intracerebral Hemorrhage
Low levels of serum triiodothyronine (T3) thyroid hormones (T4) are a strong predictor of mortality and poor prognosis in critical care patients. Few reports, however, have focused on neurocritical patients.
- Conditions
- Intracerebral Hemorrhage, Low T3 Syndrome, Neurocritical Care, Hormone Replacement Therapy
- Trial name
- NCT06353555
- Testing
- Euthyrox
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking Union Medical College Hospital
Intracerebral Hemorrhage
Neuroprotectant for Hypertensive Intracerebral Hemorrhage
Cattle encephalon glycoside and ignotin Cattle encephalon glycoside and ignotin (CEGI) injection (drug approval H22025046; Jilin Sihuan Pharmaceutical Co.
- Trial name
- NCT03546283
- Testing
- Cattle Encephalon Glycoside and Ignotin
- Where
- China
- Volunteers
- 422 people
- Sponsor
- Rong Hu, MD
Stroke
"Spot Sign" Selection of Intracerebral Hemorrhage to Guide Hemostatic Therapy
This clinical trial will enroll 110 patients from approximately 15 Canadian stroke centres. Patients coming to the emergency department with bleeding in the brain not due to trauma or other known causes who can be treated within…
- Trial name
- SPOTLIGHT (NCT01359202)
- Testing
- rfVIIa, Standard saline solution
- Where
- 15 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Dr. David Gladstone
Venous Thromboembolism, Pulmonary Embolism
Timing of Venous Thromboembolism Prophylaxis in Patients With Hypertensive Intracerebral Hemorrhage
The objective of this randomized clinical trial is to evaluate the safety and efficiency of different anticoagulation schemes with heparin for venous thromboembolism prevention in patients with hypertensive intracerebral…
- Conditions
- Venous Thromboembolism, Pulmonary Embolism, Intracerebral Hemorrhage, Deep Vein Thrombosis
- Trial name
- NCT06753786
- Testing
- Venous thromboembolism prophylaxis with unfractionated heparin or low molecular weight heparin starting within the first 2 days but not earlier than 12 hours after a hospital admission., Venous thromboembolism prophylaxis with unfractionated heparin or low molecular weight heparin starting on the 3rd day after a hospital admission.
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Pirogov Russian National Research Medical University
Ischemic Stroke, Intracerebral Hemorrhage
The Effect of Music Listening in Rehabilitation of Subacute Stroke
Music listening has many positive effects on the brain. This study aims to find out if people with stroke get better results with their rehabilitation if they listen to music during their passive hours.
- Trial name
- NCT06469619
- Testing
- Music listening
- Volunteers
- 130 people
- Sponsor
- Maria Sariola