Clinical trials: ICH - Intracerebral Hemorrhage
Intracerebral Hemorrhage, Stroke
Effect of Rosuvastatin in Intracerebral Hemorrhage
The purpose of this study is to determine whether rosuvastatin is effective in the management of acute phase of intracerebral hemorrhage and if it impact outcome by NIHSS.
- Trial name
- NCT00364559
- Testing
- Rosuvastatin
- Where
- Mexico
- Volunteers
- 75 people
- Sponsor
- Universidad Autonoma de San Luis Potosí
Acute Stroke, Ischemic Stroke
Rescue Intracranial Stenting in Acute Ischemic Stroke
In acute ischemic stroke caused by intracranial large vessel occlusion, rescue intracranial stenting has been recently a treatment option to achieve recanalization in patients with the failure of mechanical thrombectomy.
- Conditions
- Acute Stroke, Ischemic Stroke, Intracranial Atherosclerosis, Stent Stenosis
- Trial name
- RISIS (NCT04986774)
- Testing
- Rescue intracranial stenting
- Where
- Vietnam
- Volunteers
- 85 people
- Sponsor
- Can Tho Stroke International Services Hospital
Traumatic Brain Injury, Ischemic Stroke
Shared Decision Making to Improve Goals-of-Care Decisions for Families of Severe Acute Brain Injury Patients
Severe acute brain injury (SABI), including large artery acute ischemic stroke, intracerebral hemorrhage, and severe traumatic brain injury continue to be the leading cause of death and disability in adults in the U.S.
- Conditions
- Traumatic Brain Injury, Ischemic Stroke, Intracerebral Hemorrhage
- Trial name
- NCT03833375
- Testing
- Decision Aid
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- University of Massachusetts, Worcester
TBI (Traumatic Brain Injury), Status Epilepticus
Augmented Renal Clearance in Neurocritical Care
Stroke, severe brain injury, uncontrolled seizures and brain infections are the most common life-threatening neurological illnesses in the world with an estimated combined annual hospital management cost of up to 44 billion…
- Conditions
- TBI (Traumatic Brain Injury), Status Epilepticus, Bacterial Meningitis, Augmented Renal Clearance (ARC)
- Trial name
- Neuro-ARC (NCT07410624)
- Where
- 3 sites in United States, Canada
- Volunteers
- 512 people
- Sponsor
- University of Alberta
Delirium, Cognitive Impairment
Illuminating Neuropsychological Dysfunction and Systemic Inflammatory Mechanisms Gleaned After Hospitalization in Trauma-ICU Study
Cognitive skills are essential to live independently, manage finances, maintain employment, and function in society. Loss of these cognitive skills puts a tremendous burden on society as seen with dementias, Alzheimer's disease…
- Conditions
- Delirium, Cognitive Impairment, Alzheimer; Early Onset, Trauma
- Trial name
- INSIGHT-ICU (NCT03098459)
- Testing
- Non-interventional observational prospective cohort study
- Where
- United States
- Volunteers
- 432 people
- Sponsor
- Vanderbilt University Medical Center
Hemorrhagic Stroke
Esmolol for the Treatment of Hypertension After Intracerebral Hemorrhage Study (ETHICHS)
Because of its pharmacokinetic characteristics, such as short half-life and its safety profile, esmolol hydrochloride is a beta blocker suitable for venous use in the form of continuous infusion.
- Trial name
- ETHICHS (NCT03743103)
- Testing
- Brevibloc, 10 Mg/mL Intravenous Solution, Nitroprusside, Sodium
- Where
- 7 sites in Brazil
- Volunteers
- 20 people
- Sponsor
- Cristália Produtos Químicos Farmacêuticos Ltda.
Intracerebral Hemorrhage
Safety of NXY-059 for the Treatment of Patients Who Have Suffered From a Stroke
This study will determine if NXY-059 is safe in patients with an acute stroke caused by bleeding in the central nervous system. The primary objective was to assess the safety and tolerability of NXY-059 compared to placebo.
- Trial name
- NCT00075959
- Testing
- NXY-059
- Where
- 64 sites in United States
- Volunteers
- 600 people
- Sponsor
- AstraZeneca
Atrial Fibrillation, Intracerebral Hemorrhage
PREvention of STroke in Intracerebral haemorrhaGE Survivors With Atrial Fibrillation
Atrial fibrillation (AF) is the most common form of irregular heart rhythm. In people with AF, blood clots often form in the heart, which can travel to the brain.
- Trial name
- PRESTIGE-AF (NCT03996772)
- Testing
- Apixaban Oral Tablet, Dabigatran, Edoxaban Tablets
- Where
- 64 sites in Austria, France and 4 more
- Volunteers
- 319 people
- Sponsor
- Imperial College London
Intracerebral Hemorrhage
Biomarkers and Imaging Markers for ICH
Intracerebral hemorrhage (ICH) is a subtype of stroke associated with high mortality and disability. Basic and clinical research has contributed to our understanding of the complex pathophysiology in ICH.
- Trial name
- NCT06462274
- Testing
- body sample collection and imaging scan
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Southwest Hospital, China
Intracerebral Hemorrhage
Multimodal Brain Monitoring as a Prognostic Tool for Intracerebral Hemorrhage
To verify if there is an association between advanced multimodal brain monitoring parameters in the first 48h and fist 7 days of admission with intrahospital and six-months functional outcome, even when controlled to other…
- Trial name
- NCT05771662
- Where
- Portugal
- Volunteers
- 25 people
- Sponsor
- Universidade do Porto
Intracerebral Hemorrhage, Thrombectomy
A Novel Score to Predict Risk of Symptomatic Intracerebral Hemorrhage
This study sought to develop and validate a new risk stratification score (Henan predicting the risk of intracerebral hemorrhage score, Henan-PRIHS) based on intra-arterial contrast enhanced Flat Detector CT (IA-CEFDCT) to…
- Conditions
- Intracerebral Hemorrhage, Thrombectomy, Stroke
- Trial name
- NCT04554368
- Testing
- intra-arterial contrast enhanced Flat Detector CT
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Cerebrovascular Disease, Ischemic Stroke
Florida Cerebrovascular Disease Biorepository and Genomics Center
The purpose of this study is to create a state-wide biorepository and resource center for cerebrovascular diseases in Florida, which will include collecting medical history information and blood from subjects affected by…
- Conditions
- Cerebrovascular Disease, Ischemic Stroke, Transient Ischemic Attack, Intracerebral Hemorrhage
- Trial name
- NCT05491980
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Mayo Clinic
Octa, Stroke
Optical Coherence Tomography Angiography in Neurological Disease
Optical Coherence Tomography Angiography (OCTA) is a non-invasive tool that images the neurovascular structures of the eye by using near-infrared light.
- Conditions
- Octa, Stroke, Subarachnoid Hemorrhage, Intracerebral Hemorrhage
- Trial name
- NCT06797765
- Testing
- OCTA
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Intracerebral Hemorrhage
GLP-1 Receptor Agonist in Primary Intracerebral Hemorrhage: A Phase 2 Randomized Trial
Intracerebral hemorrhage (ICH) is a devastating form of acute stroke with poor clinical outcomes. Although ICH accounted only for 28.8% of incident strokes, it was responsible for nearly half of the long-term burden of stroke…
- Trial name
- GLICH (NCT07613437)
- Testing
- Semaglutide, 0.5 mg/mL
- Where
- 3 sites in China, Hong Kong
- Volunteers
- 200 people
- Sponsor
- Chinese University of Hong Kong
Intracerebral Haemorrhage, Minimally Invasive Treatment
Stereotactic Thrombolysis With Tenecteplase for Supratentorial Intracerebral Hemorrhage
This is a phase III prospective, multi-center, open-label, randomized controlled trial (RCT) with blinded endpoint assessment. It plans to enroll 768 subjects with spontaneous supratentorial intracerebral hemorrhage, who will be…
- Trial name
- STEPS (NCT07208097)
- Testing
- Stereotactic thrombolysis with Tenecteplase
- Where
- 51 sites in China
- Volunteers
- 768 people
- Sponsor
- Tongji Hospital
Hemorrhage, Pneumonia
Oral Hygiene and Prophylactic Antibiotics to Prevent Intracerebral Hemorrhage Associated Pneumonia
Project Name: Randomized Controlled Clinical Study on oral hygiene and prophylactic antibiotics to prevent Intracerebral Hemorrhage associated pneumonia Research Objectives: To evaluate the effectiveness, safety and health…
- Trial name
- OCEAN (NCT07311343)
- Testing
- wether apply enhanced oral care combined with prophylactic antibiotics
- Where
- China
- Volunteers
- 440 people
- Sponsor
- Beijing Tiantan Hospital
Intracerebral Haemorrhage, Stroke
STOP-AUST: The Spot Sign and Tranexamic Acid On Preventing ICH Growth - AUStralasia Trial
The aim of the study is to test if intracerebral haemorrhage (ICH) patients who have contrast extravasation on computed tomography angiography, the "spot sign", have lower rates of haematoma growth when treated with tranexamic…
- Trial name
- STOP-AUST (NCT01702636)
- Testing
- Tranexamic Acid
- Where
- 11 sites in Australia, Finland
- Volunteers
- 100 people
- Sponsor
- Neuroscience Trials Australia
Intracerebral Haemorrhage
STOP-MSU: Stopping Haemorrhage With Tranexamic Acid for Hyperacute Onset Presentation Including Mobile Stroke Units
The study is a prospective phase II randomised, double-blind, placebo-controlled investigator-driven trial in acute intracerebral haemorrhage patients.
- Trial name
- NCT03385928
- Testing
- Tranexamic Acid, Normal saline
- Where
- 25 sites in Australia, Finland and 3 more
- Volunteers
- 201 people
- Sponsor
- Neuroscience Trials Australia
Spontaneous Intracerebral Hemorrhage
Early-Start Antiplatelet Treatment After Neurosurgery in Patients With Spontaneous Intracerebral Hemorrhage
This study is a multicenter, prospective, open-label, endpoint-blind, randomized controlled study.Patients receiving surgical treatment for SICH were divided into groups using the random machine method.
- Trial name
- NCT04820972
- Testing
- Antiplatelet Agents
- Where
- China
- Volunteers
- 269 people
- Sponsor
- Beijing Tiantan Hospital
Intracerebral Hemorrhage
Evaluating a Prototype CT Scan for ICH Evacuation
The aim of the project is to collect pre-procedural CT scans, intra-procedural post-evacuation scans as well as immediate post-procedural CT scans to evaluate and collect feedback of two Siemens prototypes: 1) perfusion prototype…
- Trial name
- ICH-CTP II (NCT07455201)
- Testing
- DynaCT Multiphase, DynaCT Sine Spin
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Icahn School of Medicine at Mount Sinai