Clinical trials: ICU Acquired Weakness
ICU Acquired Weakness
Risk Factors of ICU-acquired Weakness
We conducted a retrospective study of critical ill patients who used ECMO during their ICU stay. ICU-AW was diagnosed at the time when patients discharged and had a Medical Research Council (MRC) sum score < 48 out of a maximal…
- Trial name
- ICU-AW (NCT04932330)
- Where
- China
- Volunteers
- 85 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Neuromuscular Blockade, Human Characteristics
Sparing in Neuromuscular Blockade in COVID 19 ICU
This is a retrospective case-controlled study of the effect of the use of a neuromuscular blockade (NMB) monitor on the consumption of NMB agents in patients under mechanical ventilation in the context of COVID-19.
- Conditions
- Neuromuscular Blockade, Human Characteristics, Complication of Medical Care, Intensive Care Unit Acquired Weakness
- Trial name
- TOF-COVID (NCT04459533)
- Testing
- TOF protocol
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Hospices Civils de Lyon
Sleep, Patient Compliance
The Effect of Ergonomic Sleep Mask Usage on Patients' Sleep Quality and Comfort
In intensive care units, the sleep quality of patients decreases considerably due to reasons such as alarm sounds of some special devices, the number of healthcare professionals working in comparison to other clinics, their…
- Conditions
- Sleep, Patient Compliance, Intensive Care Unit Acquired Weakness
- Trial name
- NCT05297188
- Testing
- ergonomic sleep mask
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Bartın Unıversity
ICU Acquired Weakness
Respiratory and Quadriceps Muscle Fatigability After an ICU Acquired Weakness
Muscle dysfunction can be lead to poor outcomes moreover ICU muscle weakness recovery are not correctly described. The investigators aimed to assess the ability for quadriceps or respiratory muscles to repeat an effort at a…
- Trial name
- NCT05396066
- Testing
- Muscle evaluation
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Groupe Hospitalier du Havre
Joint Contracture, Mechanical Ventilation
Using Continuous Passive Motion to Prevent Ankle Problems in ICU Patients
The goal of this clinical trial is to learn if continuous passive motion (CPM) helps prevent ankle joint contracture and muscle loss in critically ill, mechanically ventilated ICU patients.
- Conditions
- Joint Contracture, Mechanical Ventilation, ICU-acquired Weakness, Critical Illness
- Trial name
- NCT06944431
- Testing
- Continuous Passive Motion (CPM)
- Where
- Taiwan
- Volunteers
- 12 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Intensive Care Unit Acquired Weakness, Muscle Weakness
Early Assessment of Quadriceps Muscle Recovery by Dynamometry and 3D Ultrasound in Intensive Care Patients Under Invasive Mechanical Ventilation
Patients in intensive care often develop acquired muscle weakness (ICUAW or Intensive Care Unit Acquired Weakness) due to immobilization and muscle atrophy.
- Trial name
- DYNAMOREA (NCT07069959)
- Testing
- Early assessment of quadriceps muscle strength
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Nantes University Hospital
Mechanical Ventilation Complication, Pediatric ALL
Measuring Thickness of the Normal Diaphragm in Children Via Ultrasound.
Critically ill children treated with invasive mechanical ventilation (iMV) in a paediatric intensive care unit (PICU) may suffer from complications leading to prolonged duration of ventilation and PICU stay.
- Conditions
- Mechanical Ventilation Complication, Pediatric ALL, Intensive Care Unit Acquired Weakness
- Trial name
- NCT04589910
- Testing
- diaphragm thickness and thickening fraction
- Where
- Netherlands
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Child, Intensive Care Unit Acquired Weakness
Clinical Effectiveness of the "PICU Up!" Multifaceted Early Mobility Intervention for Critically Ill Children
While mortality in U.S. pediatric intensive care units (PICUs) is improving, surviving children frequently develop persistent physical, cognitive, and psychological impairments.
- Conditions
- Child, Intensive Care Unit Acquired Weakness, Critical Illness, Hospital Acquired Pressure Ulcer
- Trial name
- PICU Up! (NCT04989790)
- Testing
- PICU Up!
- Where
- 11 sites in United States
- Volunteers
- 1,470 people
- Sponsor
- Johns Hopkins University
ICU Acquired Weakness
Diagnosing Intensive Care Unit (ICU) Acquired Weakness
The goal of this study is to develop a non-invasive test to diagnose intensive care unit (ICU) acquired weakness that can be administered to both responsive and non-responsive patients.
- Trial name
- NCT04166630
- Testing
- Clinical Electrical Stimulator
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Emory University
ICU Acquired Weakness
Safety and Efficacy of the MyokinE100 (CL-EMS Alpha) Device in Inducing Visible Muscle Contraction in Healthy Volunteers
Every patient admitted to the Intensive Care Unit (ICU) is at risk of developing "Intensive Care Unit Acquired Weakness" (ICUAW).
- Trial name
- NCT06023511
- Testing
- Electrical muscle stimulation
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Health Discovery Labs
Liver Cirrhoses, Liver Failure
Early Cycle Ergometry for Critically-Ill Liver Failure Patients in a Transplant Intensive Care Unit
Critically-ill patients with liver disease are at high risk of developing sarcopenia and intensive care unit (ICU)-acquired weakness, which are associated with mortality and other poor outcomes.
- Conditions
- Liver Cirrhoses, Liver Failure, ICU Acquired Weakness
- Trial name
- NCT04160039
- Testing
- Cycle ergometry
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Medical College of Wisconsin
Critical Illness
The Role of NEMS for Post ICU Rehabilitation
The purpose of this study is to investigate the role of NEMS as a rehabilitation tool for muscle weakness following critical illness.
- Trial name
- NCT01717833
- Testing
- NEMS
- Where
- Greece
- Volunteers
- 120 people
- Sponsor
- University of Athens
ICU Acquired Weakness
Impact of Early Mobilization on Mechanical Ventilation Duration in Intubated Critically Ill Patients
The purpose of the present study is to compare usual care in terms of mobilization performed to intubated ICU patients to a standardized program designed to deliver early mobilization at least 5 days a week.
- Trial name
- EarlyMob (NCT02520193)
- Testing
- Protocolized early mobilization in ICU
- Where
- 23 sites in Belgium, France and 1 more
- Volunteers
- 772 people
- Sponsor
- University Hospital, Angers
Critical Illness Myopathy
NLRP3 Inflammasome and Physical Therapy in ICU-Acquired Weakness
The goal of this clinical trial is to study whether physical therapy can reduce NLRP3 inflammasome activation and muscle atrophy in patients with critical illness myopathy (CIM).
- Trial name
- PT-NLRP3-CIM (NCT07017517)
- Testing
- Motomed Letto® servo-assisted cycling + standard physiotherapy, Standard physiotherapy
- Where
- 3 sites in Chile
- Volunteers
- 24 people
- Sponsor
- University of Chile
Critical Illness, Intensive Care Unit Acquired Weakness
PRotEin Provision in Critical IllneSs
Rapid skeletal muscle wasting during critical illness had a detrimental impact on both short and long term outcomes following ICU admission.
- Trial name
- PRECISe (NCT04633421)
- Testing
- PRECISe protocol EN 8g protein/100kcal, PRECISe protocol EN 5g protein/100kcal
- Where
- 10 sites in Belgium, Netherlands
- Volunteers
- 935 people
- Sponsor
- Maastricht University Medical Center
Muscle Weakness
Evaluation of Muscle Strength by Transcutaneous Electrical Stimulation
Acquired Neuromyopathy of Resuscitation (NMAR) is a common condition. Its diagnosis is difficult and often late because it is based on a clinical assessment of muscle strength (MRC score) requiring the patient to be awake and…
- Trial name
- STRENGTH-ICU (NCT03270163)
- Testing
- Transcutaneous electrical stimulation, Magnetic stimulation, ultrasound measurement
- Where
- France
- Volunteers
- 47 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Intensive Care Unit (ICU) Acquired Weakness (ICU - AW), Acquired Brain Injury (Including Stroke)
Functional Electrical Stimulation to Treat Critical Neuromyopathy After Severe Stroke: a Pilot Study.
This study aims to evaluate the effectiveness of physiotherapy treatment combined with functional electrical stimulation (FES) in a small group of patients with severe acquired brain injury (SABI) of vascular origin and with a…
- Trial name
- RISE (NCT07130929)
- Testing
- Functional Electrical Stimulation, Conventional physiotherapy
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
ICU Acquired Weakness
ICU-Recover Box 2.0, Smart Technology for Home Monitoring of ICU Patients
Smart technology could improve quality of care in patients who have been admitted to the ICU and have been discharged from ICU and hospital, by early diagnosis of complications and early (ambulatory) treatment.
- Trial name
- NCT07162948
- Testing
- The ICU-Recover Box: using smart technology for monitoring health status after ICU admission Pilot 2.0
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Leiden University Medical Center
Intensive Care Unit Acquired Weakness, Shock, Septic
Hemodynamic Phenotype-Based,Capillary Refill Time-Targeted Resuscitation In Early Septic Shock:ANDROMEDA-SHOCK-2
Over-resuscitation including fluid overload has been associated with increased morbidity (prolonged duration of organ failure) and mortality in septic shock.
- Trial name
- ANDROMEDA-FR (NCT06062303)
- Testing
- Usual care (UC)
- Where
- France
- Volunteers
- 180 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Intensive Care Unit (ICU) Acquired Weakness (ICU - AW), Muscle Weakness
Nutrient Pattern Analysis in Critically Ill Patients (NAChO)
Little is known about nutritional Parameters that potentially influence the course of intensive-care unit acquired weakness (ICU - AW).
- Trial name
- NAChO (NCT02839018)
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern