Clinical trials: ICU Acquired Weakness
ICU, Trauma Injury
Current Situation and Analysis of ICU Management for Severe Trauma Patients in China
Over the past 10 years, there has not been a consensus on ICU nursing management based on the concept of injury control. Case management for patients with serious trauma continues to be initiated in general services and after…
- Conditions
- ICU, Trauma Injury, ICU Acquired Weakness
- Trial name
- NJJLISTP (NCT04944537)
- Testing
- No Intervention
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Lulu Gu
Aortic Diseases, Intensive Care Unit Syndrome
Muscle Recovery Following Aortic Surgery Induced ICUAW.
To identify determinants of 'good and bad recovery' from ICUAW and build knowledge around the timing of these processes. Also, the investigators want to discover the effects of ICUAW on physical function and HRQoL following…
- Conditions
- Aortic Diseases, Intensive Care Unit Syndrome, Intensive Care Neuropathy, Intensive Care (ICU) Myopathy
- Trial name
- VARIANCE (NCT03714399)
- Where
- United Kingdom
- Volunteers
- 31 people
- Sponsor
- Barts & The London NHS Trust
Intensive Care Unit Acquired Weakness
IMT Outcomes in Sufferers of Severe Walking Disabilities and Intensive Care Unit Acquired Weakness
Intensive care unit-acquired weakness (ICU-acquired weakness) may be caused by a variety of different causes. Several studies have shown that ICU-acquired weakness occurs in up to 30% of critically ill patients.
- Trial name
- NCT06210763
- Testing
- Threshold IMT and traditional physical therapy program, traditional physiotherapy program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Septic Shock
Interest of Plasma microRNAs
ICU acquired muscle weakness (IAMW) is a common disease that is associated with high morbidity and mortality. Patients with septic shock are particularly at risk.
- Trial name
- µARN (NCT02464371)
- Testing
- kinetic of microRNAs
- Where
- 2 sites in France
- Volunteers
- 58 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Polyneuropathy, Critical Illness
Neuromuscular Electrical Stimulation for Intensive Care Unit-acquired Weakness Assessment
The purpose of this study is to determine whether early neuromuscular electrical stimulation is effective in the prevention of neuromuscular weakness in critical ill patients.
- Trial name
- ENS (NCT02706587)
- Testing
- Neuromuscular electrical stimulation
- Where
- France
- Volunteers
- 102 people
- Sponsor
- Institut Mutualiste Montsouris
Intensive Care Unit-acquired Weakness
Skeletal Muscle Regeneration in Survivors of Critical Illness: How to Prevent Satellite Cell Failure?
Modern intensive care enables patients to survive insults that in the past would have been supralethal. Nonetheless, increased number of survivors suffer from failed functional outcomes associated with prolonged muscle weakness…
- Trial name
- SATELLITE (NCT05671614)
- Where
- Czechia
- Volunteers
- 50 people
- Sponsor
- Charles University, Czech Republic
Critical Illness, Lung Function Decreased
Effect of Early Mobilization on Regional Lung Ventilation Assessed by EIT
Changes in pulmonary ventilation and perfusion by EIT to out-of-bed activity in critically ill patients
- Conditions
- Critical Illness, Lung Function Decreased, ICU Acquired Weakness
- Trial name
- NCT04081129
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Yun Long
Sarcopenia, ICU Acquired Weakness
ICU Associated Weakness and Bedside Ultrasound Assessment
ICU-associated weakness is a common experience for people following a critical illness. It is associated with important patient and system-relevant outcomes.
- Trial name
- NCT04095533
- Testing
- Tibialis anterior muscle cross-sectional area assessment by ultrasound, Muscle strength assessment
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- University of Calgary
Implementation Science, Delirium
Determinants of Implementation Success Coordinating Ventilator, Early Ambulation and Rehabilitation Efforts
There is a fundamental gap between the discovery of proven-effective intensive care unit (ICU) sedation, mechanical ventilation, mobility, and symptom management strategies and approaches that can equip ICU providers with the…
- Conditions
- Implementation Science, Delirium, Intensive Care Unit Acquired Weakness, Pain
- Trial name
- DISCOVER-ICU (NCT04249141)
- Testing
- Survey and concept mapping
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ohio State University
Critical Illness, Intensive Care Unit Acquired Weakness
Virtual Reality Rehabilitation on the Intensive Care Unit for Critically Ill Patients
Feasibility study of the use of an interactive Virtual Reality device in rehabilitation of critically ill patients on the Intensive Care Unit.
- Trial name
- VRR-ICU (NCT05591248)
- Testing
- VRR
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
ICU Acquired Weakness
Impact of Early Mobilization on Mechanical Ventilation Duration in Intubated Critically Ill Patients
The purpose of the present study is to compare usual care in terms of mobilization performed to intubated ICU patients to a standardized program designed to deliver early mobilization at least 5 days a week.
- Trial name
- EarlyMob (NCT02520193)
- Testing
- Protocolized early mobilization in ICU
- Where
- 23 sites in Belgium, France and 1 more
- Volunteers
- 772 people
- Sponsor
- University Hospital, Angers
ICU Acquired Weakness
Evaluation of Diaphragmatic Function and Quadriceps Muscle Thickness in Patients Receiving High Protein Nutrition
Different Protein Doses' Effect on Diaphragmatic Function and Quadriceps Thickness
- Trial name
- NCT06025760
- Testing
- patients who will receive 2 gm protein/kg/day will be evaluated by ultrasound for diaphragmatic function and quadriceps muscle thickness
- Volunteers
- 32 people
- Sponsor
- Zagazig University
COVID-19, Acute Respiratory Distress Syndrome
Physical Rehabilitation in ICU in ARDS Patients With COVID-19
The primary aim of this study is to evaluate the effect of physical rehabilitation performed in intensive care unit on the range of joint motions and muscle strength of survivors following discharge from intensive care unit in…
- Conditions
- COVID-19, Acute Respiratory Distress Syndrome, Rehabilitation, Intensive Care Unit Acquired Weakness
- Trial name
- NCT04435080
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Koç University
ICU Acquired Weakness
Exploring Novel Biomarkers of ICU-AW in Mechanically Ventilated Children at the Molecular Level
Acquired weakness (AW) is a common complication among patients in the Intensive Care Unit (ICU). It is a systemic muscle weakness and dysfunction associated with critical illness, often related to prolonged bed rest, mechanical…
- Trial name
- NCT07150650
- Testing
- ICU-AW
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Children's Hospital of Fudan University
Intensive Care (ICU) Myopathy, Intensive Care Unit Acquired Weakness
Effect of Neurophysiological Facilitation Techniques in Intensive Care Patients
The aim of this study was to investigate the effect of neurophysiological facilitation techniques on respiratory and functional levels in intensive care patients.
- Trial name
- NCT05282576
- Testing
- NPF Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Saglik Bilimleri Universitesi
ICU-acquired Weakness, Mechanical Ventilation
eCASH and Early Goal-Directed Mobilization to Prevent ICU-Acquired Weakness
This single-center, prospective, randomized controlled trial aims to evaluate whether an eCASH concept-based analgesia and sedation strategy combined with early goal-directed mobilization can reduce the incidence of intensive…
- Conditions
- ICU-acquired Weakness, Mechanical Ventilation, Critical Illness
- Trial name
- eCASH-EGDM (NCT07677488)
- Testing
- eCASH-Based Analgesia and Sedation Strategy Combined With Early Goal-Directed Mobilization, Routine ICU Nursing Care
- Where
- China
- Volunteers
- 70 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Sarcopenia, Covid19
Sarcopenia and Related Factors in Coronavirus Disease 2019 (COVID-19) Following Intensive Care
The primary aim of this study is to evaluate the patients who had pneumonia or severe acute respiratory distress syndrome (ARDS) due to COVID-19 in terms of sarcopenia and related factors following Intensive Care Unit (ICU).
- Conditions
- Sarcopenia, Covid19, Intensive Care Unit Acquired Weakness
- Trial name
- NCT05474157
- Testing
- Standard care treatment for COVID-19 in Intensive Care Unit
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Koç University
ICU Acquired Weakness
Safety and Efficacy of the MyokinE100 (CL-EMS Alpha) Device in Inducing Visible Muscle Contraction in Healthy Volunteers
Every patient admitted to the Intensive Care Unit (ICU) is at risk of developing "Intensive Care Unit Acquired Weakness" (ICUAW).
- Trial name
- NCT06023511
- Testing
- Electrical muscle stimulation
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Health Discovery Labs
Post Intensive Care Syndrome
Impact of Frailty and ICU-AW on Post-ICU Fatigue Self-reported
After a prolonged stay in Intensive Care Unit (ICU), fatigue is the most common symptom reported by patients in the Post Intensive Care Syndrome (PICS).
- Trial name
- FICUF (NCT05984069)
- Testing
- observational prospective data collection
- Where
- 2 sites in France
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
ICU Acquired Weakness
ICU CONNECT: Study Comparing EMG in Healthy Volunteers and ICU Patients.
This study is testing whether a non-invasive nerve monitoring device (TetraGraph) can accurately detect early signs of ICU-acquired weakness by comparing readings from the device with standard nerve conduction/EMG tests done by a…
- Trial name
- ICU CONNECT (NCT07699562)
- Testing
- TetraGraph, Electromyography, Nerve conduction studies
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Endeavor Health