Clinical trials: ICU Mortality
Gastrointestinal Hemorrhage, Critical Illness
Gastrointestinal Bleeding in Critically Ill Patients
This prospective cohort study aims to determine the prevalence of gastrointestinal bleeding among critically ill patients admitted to intensive care units, identify independent risk factors, and describe clinical outcomes…
- Trial name
- NCT07822958
- Volunteers
- 310 people
- Sponsor
- Assiut University
Acute Respiratory Infections, Critical Illness in Children
Serum Vitamin D Status in Critically Ill Children With Acute Respiratory Infections
Acute respiratory infections (ARIs) are among the leading causes of hospitalization, morbidity, and mortality in children worldwide, particularly among critically ill patients admitted to pediatric intensive care units (PICUs).
- Conditions
- Acute Respiratory Infections, Critical Illness in Children, Vitamin D Deficiency, Pediatric Respiratory Infections
- Trial name
- VITD-ARI (NCT06547749)
- Testing
- Serum 25-Hydroxyvitamin D Assessment
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- Assiut University
Sepsis, Critical Illness
Peripheral Perfusion Index Trajectory to Predict 28-Day Mortality in Patients With Sepsis in the Intensive Care Unit
Sepsis is a life-threatening condition caused by the body's overwhelming response to infection, and it remains a leading cause of death in intensive care units.
- Trial name
- PERFUSE-ICU (NCT07740304)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Trakya University
Cardiovascular Disease
Retrospective Safety Study to Compare Mortality in Intensive Care Unite (ICU) Patients Undergoing Echocardiography With or Without DEFINITY®
Retrospective analysis to observe changes in short term mortality
- Trial name
- DEF-418 (NCT01299649)
- Where
- United States
- Volunteers
- 4,300,000 people
- Sponsor
- Lantheus Medical Imaging
Acute Kidney Injury
Frailty and Outcomes in Critically Ill Patients Receiving CRRT
This nationwide observational cohort study will investigate the association between frailty, chronological age, and clinical outcomes in critically ill patients receiving continuous renal replacement therapy (CRRT) in Sweden.
- Trial name
- CRRT-AF (NCT07837219)
- Volunteers
- 22,000 people
- Sponsor
- Karolinska Institutet
Critical Care
Checklist During Multidisciplinary Visits for Reduction of Mortality in Intensive Care Units
CHECKLIST-ICU will be a cluster randomized trial to ascertain whether the use of an intervention including 1) checklists with assessment of daily goals during the multidisciplinary visit, and 2) clinician prompting can reduce…
- Trial name
- CHECKLIST-ICU (NCT01785966)
- Testing
- Daily checklist and clinician prompting
- Where
- Brazil
- Volunteers
- 13,637 people
- Sponsor
- Hospital do Coracao
Chronic Cardiovascular Disease, Acute Cardiovascular Disease
Chronic and Acute Cardiovascular Diseases in Elderly Intensive Care Patients
Very old patients are a rapidly growing and vulnerable population in acute cardiovascular care but remain underrepresented in clinical trials.
- Conditions
- Chronic Cardiovascular Disease, Acute Cardiovascular Disease, Frailty
- Trial name
- NCT07385482
- Where
- Germany
- Volunteers
- 4,000 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Severe Mental Illness, Severe Mental Disorder
Outcome of Patients With Severe Mental Illness in the Intensive Care Unit
Severe mental illnesses (SMIs), such as major depression, schizophrenia, and bipolar disorder, carry a significant prevalence among patients admitted to the intensive care unit (ICU), estimated at an average of 19%.
- Trial name
- REPSYRE (NCT07705802)
- Testing
- Observational follow-up
- Where
- 30 sites in France
- Volunteers
- 2,000 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Fluid and Electrolyte Imbalance, Anesthesia
BIA-Guided vs. Conventional Fluid Resuscitation in ICU Patients
In this study aimed to compare bioelectrical impedance analysis (BIA)-guided fluid resuscitation with conventional fluid management strategies in patients admitted to the intensive care unit (ICU) following major surgery.
- Trial name
- BIA-FLUID (NCT07142083)
- Testing
- Bioelectrical Impedance Analysis (BCM), Conventional Fluid Management
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ondokuz Mayıs University
Carbapenem Resistant Bacterial Infection
Machine Learning in the ICU: Predicting Mortality in Bloodstream Infections (ICU:Intensive Care Unit)
Using our own patient data, our study aimed to predict mortality that can develop in Carbapenem-resistant Gram-negative bacilli bloodstream infections with a machine learning-based model.
- Trial name
- ICU (NCT06167083)
- Testing
- Machine Learning to Estimate Mortality
- Where
- Turkey (Türkiye)
- Volunteers
- 197 people
- Sponsor
- Kocaeli University
Postoperative Mortality, Frailty at Older Adults
Predictive Value of Frailty Scores and Admission Laboratory Markers for Postoperative ICU Mortality
This prospective observational study aims to evaluate the predictive value of the Clinical Frailty Scale (CFS), the Katz Activities of Daily Living (ADL) scale, and admission laboratory markers for postoperative mortality among…
- Conditions
- Postoperative Mortality, Frailty at Older Adults, Activities of Daily Living, Postoperative Complications
- Trial name
- GERI-MORTAL (NCT07279519)
- Where
- Turkey (Türkiye)
- Volunteers
- 393 people
- Sponsor
- Malatya Egitim Ve Arastirma Hastanesi
Postoperative Intracranial Hematoma, Postoperative Intracranial Haemorrhage
A New Approach in Intensive Care Unit Consciousness Assessment: FIVE Score
1. The primary aim of this study is to investigate the correlation between the length of ICU stay and a newly developed FIVE score in neuro-intensive care patients. 2.
- Conditions
- Postoperative Intracranial Hematoma, Postoperative Intracranial Haemorrhage, Supratentorial Cancer, Infratentorial Neoplasms
- Trial name
- NCT06036732
- Where
- Turkey (Türkiye)
- Volunteers
- 223 people
- Sponsor
- Istanbul University - Cerrahpasa
ARDS, Acute Respiratory Distress Syndrome
Effect of Prone Positioning on Mortality in Patients With Mild to Moderate Acute Respiratory Distress Syndrome.
Acute respiratory distress syndrome (ARDS) accounts for almost 10% of intensive care units (ICU) admissions. Three ARDS stages have been defined, based on the PaO2/FIO2 ratio measured with positive end-expiratory pressure (PEEP)…
- Conditions
- ARDS, Acute Respiratory Distress Syndrome, Intensive Care Unit, Mechanical Ventilation
- Trial name
- PROMILD (NCT05056090)
- Testing
- Patients will receive MV in PP
- Where
- France
- Volunteers
- 656 people
- Sponsor
- University Hospital, Grenoble
D012139, D003924
Metformine as a Protective Factor of Mortality in Type 2 Diabetic Patients Admitted to the ICU for Septic Shock.
Septic shock is a major complication of sepsis and is one of the leading causes of admission to intensive care unit (ICU) as well as a major contributor to global mortality, accounting for one in five deaths worldwide and…
- Trial name
- SEPSMET (NCT07591402)
- Where
- France
- Volunteers
- 2,740 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Critical Illness, ARDS
Replacing Protein Via Enteral Nutrition in a Stepwise Approach in Critically Ill Patients
In this study, we will explore the feasibility of a randomized controlled trial that will compare high protein dose from ICU day 6 to 14 with moderate protein intake.
- Conditions
- Critical Illness, ARDS, Septic Shock, Multiple Trauma
- Trial name
- Replenish (NCT03480555)
- Testing
- Replenish Protein, Standard protein
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- King Abdullah International Medical Research Center
Acute Respiratory Distress Syndrome
Pulmonary Microbiota and ARDS Mortality
Acute respiratory distress syndrome (ARDS) is due to diffuse and severe lung inflammation. Despite intensive research, few therapeutics have emerged and treatment is still mostly symptomatic.
- Trial name
- MicrA (NCT04133558)
- Testing
- tracheal aspirate during routine care
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University of Bordeaux
Diabetes Mellitus, Covid19
Clinical Phenotype and Outcomes of Inpatients With COVID-19 and Diabetes
Patients with diabetes have been listed as people at higher risk for severe illness from COVID-19. Moreover, the relationship between diabetes-related phenotypes and the severity of COVID-19 remains unknown.
- Trial name
- NCT04550403
- Where
- Italy
- Volunteers
- 757 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Intensive Care Unit, Mortality
Capillary Refill Time Calculated With a Video-assisted Method Has a Better Reproducibility Than Visual Method in Critically Ill Patients
Capillary refill time is the time it takes for the skin to regain its initial colour after moderate pressure. It is usually performed on the patient index finger, middle finger or ring finger with the examiner's thumb and index…
- Conditions
- Intensive Care Unit, Mortality, Reliability
- Trial name
- EVITREC (NCT05573659)
- Testing
- time of cutaneous recoloration, video assisted cutaneous recoloration
- Where
- France
- Volunteers
- 59 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Covid19
Glutamine Supplementation and Short-term Mortality in Covid-19
The aim of this study is to investigate the effect of parenteral L-Glutamine supplementation added to enteral nutrition on short-term ICU mortality (7 days) in Covid-19 diseased patients.
- Trial name
- NCT04909905
- Testing
- Standard enteral nutrition, Glutamine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Mortality
Prognostic Value of Lactates in ICU
he aim of this prospective, analytic trial was to evaluate the accuracy of blood lactates levels in predicting mortality in ICU patients.
- Trial name
- NCT04792736
- Testing
- Blood lactate level
- Where
- 2 sites in Tunisia
- Volunteers
- 135 people
- Sponsor
- Mongi Slim Hospital