Clinical trials: ICU Mortality
Mechanically Ventilated Patients
Mechanical Ventilation Practices in Uganda's Intensive Care Units
A prospective cohort study carried out in four ICUs in Uganda. All patients, 18 years and above initiated on mechanical ventilation will be recruited.
- Trial name
- NCT03800849
- Where
- Uganda
- Volunteers
- 214 people
- Sponsor
- Makerere University
Ventilator Associated Pneumonia, Multi-antibiotic Resistance
Ventilator Associated Pneumonia by Multi-Drug Resistant Organism
Ventilator-associated pneumonia (VAP) is an infection of the pulmonary parenchyma in patients exposed to invasive mechanical ventilation for at least 48 h and is part of ICU-acquired pneumonia.
- Trial name
- VAP-MDR (NCT05549427)
- Testing
- Ventilation
- Where
- Oman
- Volunteers
- 319 people
- Sponsor
- Sultan Qaboos University
Mortality
Prognostic Value of Lactates in ICU
he aim of this prospective, analytic trial was to evaluate the accuracy of blood lactates levels in predicting mortality in ICU patients.
- Trial name
- NCT04792736
- Testing
- Blood lactate level
- Where
- 2 sites in Tunisia
- Volunteers
- 135 people
- Sponsor
- Mongi Slim Hospital
Septic Shock, Vasodilatory Shock
Vasopressin Use in Septic Shock From Türkiye
The goal of this observational study is to examine the early hemodynamic effects and clinical outcomes of vasopressin use in patients with septic shock.
- Conditions
- Septic Shock, Vasodilatory Shock, Critical Illness Sepsis, Severe, Critical Illness
- Trial name
- (VASCO-TURK) (NCT06953297)
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people
- Sponsor
- Karadeniz Technical University
Intensive Care Medicine
Predictive Value of the mNutric Score and Survival Analysis in Critically Ill Patients Hospitalised in the Intensive Care Unit
Our study is an observational study and the follow-up hematological tests of patients in the intensive care unit will be recorded during their first admission.
- Trial name
- NCT06912204
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Amasya University
Sepsis - to Reduce Mortality in the Intensive Care Unit, Trauma Coagulopathy
ROTEM in Sepsis Trauma Outcome in Intensive Care
This prospective observational study aims to investigate the ability of advanced ROTEM analysis using Principal Component Analysis (PCA) to detect early signs of disseminated intravascular coagulation (DIC) and trauma-induced…
- Trial name
- ROSTIC (NCT06891599)
- Where
- Sweden
- Volunteers
- 600 people
- Sponsor
- Region Stockholm
Parenteral Nutrition
Study Comparing a Soybean Oil-Based With an Olive Oil-Based Lipid Emulsion in ICU Patients Requiring TPN
Many hospitalized patients who are malnourished or not eating receive intravenous feeding or total parenteral nutrition (TPN). Despite improving nutrition, TPN may increase the risk of infections and hospital complications.
- Trial name
- TPN2 (NCT00672854)
- Testing
- ClinOleic 20% Intravenous Emulsion, Intralipid, 20% Intravenous Emulsion
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Emory University
Intensive Care Unit Syndrome, Mechanical Ventilation Complication
Ketamine Infusion as Sedative Analgesic in Severe ARDS
To evaluate whether ketamine is a safe sedative-analgesic agent to be used in an intensive care unit (ICU) setting as compared to traditionally used agents such as propofol, opioids, and midazolam
- Conditions
- Intensive Care Unit Syndrome, Mechanical Ventilation Complication, Sedatives and Hypnotics Causing Adverse Effects in Therapeutic Use, Delirium
- Trial name
- KISS (NCT04818827)
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Interfaith Medical Center
Acute Respiratory Distress Syndrome
Pulmonary Microbiota and ARDS Mortality
Acute respiratory distress syndrome (ARDS) is due to diffuse and severe lung inflammation. Despite intensive research, few therapeutics have emerged and treatment is still mostly symptomatic.
- Trial name
- MicrA (NCT04133558)
- Testing
- tracheal aspirate during routine care
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University of Bordeaux
Intensive Care Unit, Mortality
Analysis of the Evolution of Mortality in an Intensive Care Unit
The intensive care units is of the main components of modern healthcare systems. Formally, its aim is to offer the critically ill health care fit to their needs; ensuring that this health care is appropriate, sustainable, ethical…
- Conditions
- Intensive Care Unit, Mortality, Epidemiology, Respiration, Artificial
- Trial name
- NCT05261607
- Where
- Spain
- Volunteers
- 27,463 people
- Sponsor
- Hospital Universitario Getafe
Mortality in Intensive Care Units
Is the PaO₂/PaCO₂ Ratio Associated With ICU Mortality Independent of Oxygen Saturation and Mean Arterial Pressure?
The goal of this observational study is to learn about the Association of the PaO₂/PaCO₂ Ratio with ICU Mortality Independent of Oxygen Saturation and Mean Arterial Pressure
- Trial name
- RATIO-MIMIC (NCT07301359)
- Volunteers
- 1,776 people
- Sponsor
- Tanta University
Acute Respiratory Failure, Shock
Impact of Early Enteral vs. Parenteral Nutrition on Risk of Gastric-Content Aspiration in Patients Requiring Mechanical Ventilation and Catecholamines
To evaluate the impact of enteral nutrition on microaspiration of gastric content and pharyngeal secretions
- Trial name
- NCT03411447
- Testing
- Parenteral nutrition, Enteral nutrition
- Where
- 6 sites in France
- Volunteers
- 139 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Frailty, Mortality
Determining the Prevalence of Frailty and Evaluating Its Relationship With Mortality.
Covid-19 patients admitted to the intensive care unit of Selcuk University Hospital were included in the study. Clinical frailty score was given during admission to the intensive care unit.
- Conditions
- Frailty, Mortality, COVID-19
- Trial name
- NCT06330883
- Testing
- Prognosis
- Where
- Turkey (Türkiye)
- Volunteers
- 148 people
- Sponsor
- Selcuk University
Cardiac Disease, Cardiac Ischemia
Assessment of Patients Undergoing Cardiac Surgery and Admitted to the Intensive Care Unit
The objective of this study is to investigate the incidence of death and early postoperative complications, identify potential risk factors, and examine the demographic characteristics of patients and epidemiology of…
- Conditions
- Cardiac Disease, Cardiac Ischemia, Cardiac Valve Disease
- Trial name
- BraSIS-2 (NCT06154473)
- Testing
- Open heart surgery group., Percutaneous cardiovascular surgery group.
- Where
- Brazil
- Volunteers
- 528 people
- Sponsor
- Hospital Israelita Albert Einstein
Metabolic Acidosis, Acid-Base Imbalance
Frequency of Metabolic Acidosis in the Pediatric Intensive Care Unit
Metabolic acidosis is one of the most common acid-base disturbances encountered in critically ill children and often reflects underlying disease severity.
- Conditions
- Metabolic Acidosis, Acid-Base Imbalance, Critical Illness in Children
- Trial name
- NCT07803263
- Volunteers
- 140 people
- Sponsor
- Assiut University
Early Neonatal Mortality
A Randomized Trial of Providing BCG Vaccination Immediately
Recent studies show that BCG vaccination reduces neonatal mortality by more than 40%. This effect cannot be explained by prevention of tuberculosis, which is very rare among infants.
- Trial name
- NCT01989026
- Testing
- BCG
- Where
- Guinea-Bissau
- Volunteers
- 3,361 people
- Sponsor
- Bandim Health Project
Postoperative Intracranial Hematoma, Postoperative Intracranial Haemorrhage
A New Approach in Intensive Care Unit Consciousness Assessment: FIVE Score
1. The primary aim of this study is to investigate the correlation between the length of ICU stay and a newly developed FIVE score in neuro-intensive care patients. 2.
- Conditions
- Postoperative Intracranial Hematoma, Postoperative Intracranial Haemorrhage, Supratentorial Cancer, Infratentorial Neoplasms
- Trial name
- NCT06036732
- Where
- Turkey (Türkiye)
- Volunteers
- 223 people
- Sponsor
- Istanbul University - Cerrahpasa
Traumatic Brain Injuries, Brain Injuries,Traumatic
Doppler Ultrasonography Parameters and Mortality in Traumatic Brain Injury
The purpose of this study is to find out whether blood flow measurements of the brain and neck arteries, obtained with bedside Doppler ultrasonography are associated with neurological outcome and survival in adult patients with…
- Trial name
- NCT07890259
- Testing
- Transcranial and Carotid Doppler Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Inonu University
Acute Respiratory Distress Syndrome (ARDS)
Pirfenidone to Prevent Fibrosis in Ards.
Acute respiratory distress syndrome (ARDS) is a severe form of acute lung injury and a major cause of Intensive Care Unit (ICU) admission worldwide.
- Trial name
- PIONEER (NCT05075161)
- Testing
- Pirfenidone
- Where
- 17 sites in Italy, Kazakhstan
- Volunteers
- 130 people
- Sponsor
- Università Vita-Salute San Raffaele
Red Blood Cell Transfusions, Sex Differences
Effects of Donor-recipient Sex-matched Blood Transfusion on Patient Outcomes
Red blood cell (RBC) transfusions are selected based upon matching donor and recipient blood group: donor and recipient sex are not considered when selecting blood for transfusion.
- Conditions
- Red Blood Cell Transfusions, Sex Differences, Health Services, Critically Ill Intensive Care Unit Patients
- Trial name
- SexMATTERS RCT (NCT06840756)
- Testing
- Sex-mismatched red blood cell transfusions, Sex-matched red blood cell transfusions
- Where
- 8 sites in Canada
- Volunteers
- 11,082 people
- Sponsor
- Michelle Zeller