Clinical trials: ICU Mortality
Elderly Patients Visiting the Emergency Department
Impact on Mid-term Mortality of Guidelines for ICU Admission of Elderly Patients Arriving in Emergency Departments
Admitting a very elderly patient to the Intensive Care Unit (ICU) is one of the most difficult clinical challenges in medicine. There are few data to help guide clinicians in this area: estimates of the benefits of ICU admission…
- Trial name
- ICECUBII (NCT01508819)
- Testing
- recommendations to admit to ICU all the patients included
- Where
- France
- Volunteers
- 3,036 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anesthesia, Surgery--Complications
PACU for Postoperative Care After Major Thoracic and Abdominal Surgery
The aim of this study is to demonstrate the efficacy and safety of a specialised post-anaesthetic care unit (PACU) to a conventional intensive care unit (ICU) in adult patients after major thoracic and abdominal surgery.
- Trial name
- NCT05046925
- Testing
- postoperatively transferral to PACU, postoperatively transferral to ICU
- Where
- China
- Volunteers
- 18,000 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Morality
Anticardiolipin Autoantibodies and Mortality in Septic Patients
The detection of antiphospholipid antibodies (aPL) is of interest because of their importance in the pathogenesis of arterial or venous thrombosis and their responsibility for a wide spectrum of clinical manifestations such as…
- Trial name
- aCLsepsis (NCT04685278)
- Testing
- Blood samples
- Where
- Tunisia
- Volunteers
- 50 people
- Sponsor
- Military Hospital of Tunis
Critical Illness, Cancer
Mean Platelet Volume (MPV) as an Early Predictor of Mortality in Intensive Care Patients With Cancer
This study aims to investigate whether Mean Platelet Volume (MPV) and other blood count parameters measured at admission can predict mortality in cancer patients admitted to the intensive care unit (ICU).
- Conditions
- Critical Illness, Cancer, Mortality
- Trial name
- MPV-CICU (NCT07656311)
- Where
- Turkey (Türkiye)
- Volunteers
- 425 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Mechanical Ventilation Complication, Mechanical Power
LPP , MP and DP:Relation With Mortality and SOFA in Mechanically Ventilated Patients in ER, Ward and ICU
Prospective, observational, longitudinal study, September 2019 to March 2020 of all adult patients who required invasive mechanical ventilation treated at General Hospital of Zone 11 IMSS in Piedras Negras, Coahuila.
- Conditions
- Mechanical Ventilation Complication, Mechanical Power, Driving Pressure, Lung Protective Ventilation
- Trial name
- LUMEDRI-MORT (NCT04193254)
- Where
- Mexico
- Volunteers
- 63 people
- Sponsor
- JOSE IVAN RODRIGUEZ DE MOLINA SERRANO
Mechanical Ventilation Complication, Ventilator Induced Lung Injury
Mechanical Power and Mortality in Mechanically Ventilated Adults
This prospective observational cohort study aims to investigate the relationship between mechanical power during the first 72 hours of invasive mechanical ventilation and 28-day mortality in mechanically ventilated adult patients…
- Conditions
- Mechanical Ventilation Complication, Ventilator Induced Lung Injury, ARDS, ICU Mortality (Survival Rate)
- Trial name
- NCT07836153
- Where
- Egypt
- Volunteers
- 116 people
- Sponsor
- Zagazig University
Lean Body Mass
Does Muscle Mass At Intensive Care Unit Admission Determine Mortality: the Memo Study
This retrospective monocentric study aims to investigate whether a low muscle mass at ICU admission and its loss over the ICU stay predicts mortality, and in what proportion we can counteract it by nutritional support.
- Trial name
- MEMO (NCT05834894)
- Testing
- exposure(s) of interest : intensive care unit
- Where
- Switzerland
- Volunteers
- 4,000 people
- Sponsor
- University Hospital, Geneva
Critical Illness, Intensive Care
Critical Illness Outcomes Study
We will test whether the way that an intensive care unit is organized can influence patient related outcomes such as mortality. We will test whether who works in the ICU, and how the ICU is managed will affect the care received…
- Conditions
- Critical Illness, Intensive Care, Intensive Care Unit
- Trial name
- CIOS (NCT01109719)
- Where
- United States
- Volunteers
- 6,000 people
- Sponsor
- National Institute of General Medical Sciences (NIGMS)
Right Heart Failure
Serial Multiparametric Evaluation of Right Ventricular Function After Left Ventricular Assist Device Implantation
The primary purpose of this study is to investigate the evolution of Right Ventricular (RV) function before and after left ventricular assist device (LVAD) implantation, using novel echocardiographic quantification of RV size and…
- Trial name
- EuroEchoVAD (NCT03552679)
- Testing
- Echocardiography
- Where
- 9 sites in Germany, Hungary and 5 more
- Volunteers
- 600 people
- Sponsor
- Erasmus Medical Center
Inflammatory Response
Inflammatory Anemia Associated Parameters in Septic Patients
1. To observe the changes in the inflammatory anemiaassociated parameters of patients with sepsis in the early stage of intensive care unit (ICU) admission. 2. To evaluate their association with 28-days mortality 3.
- Trial name
- NCT04281888
- Volunteers
- 100 people
- Sponsor
- Assiut University
Inpatient Hospitalization, Intensive Care Unit Admission, Inpatient Mortality, Sepsis and Septic Shock
Linking Novel Diagnostics With Data-Driven Clinical Decision Support in the Emergency Department
The primary objective of this study is to validate the use of an electronic clinical decision support (CDS) tool, TriageGO with Monocyte Distribution Width (TriageGO-MDW), in the emergency department (ED).
- Trial name
- NCT05335135
- Testing
- TriageGO-MDW Clinical Decision Support, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 300,000 people, healthy volunteers welcome
- Sponsor
- Stocastic, LLC
Critical Illness
Scoring Systems in ICU and Malnutrition
The objective of the present study was to compare the ability of acute physiology and chronic health evaluation (APACHE) scoring systems with the combination of an anthropometric variable score "adductor pollicis muscle (APM)…
- Trial name
- NCT03318965
- Volunteers
- 304 people
- Sponsor
- Shahid Beheshti University
Anaphylaxis
Epidemiology and Outcome of Anaphylactic Shocks Admitted to Intensive Care Unit
Anaphylaxis is a severe life-threatening reaction following exposure to an antigen. Its incidence is progressively increasing in the general population over years, accompanied with an increased number of hospitalizations.
- Trial name
- ANAPHYLASHOCK (NCT04290507)
- Where
- 2 sites in France
- Volunteers
- 339 people
- Sponsor
- Central Hospital, Nancy, France
Intensive Care Unit Patients
Prognosis Value of Bioimpedance Analysis (BIA) Phase Angle at Admission in Intensive Care Unit (ICU) Patients
Critically ill patients feature a loss of fat-free mass (FFM) up to 440 g/day, which is associated with increased morbidity and prolonged recovery.
- Trial name
- PAP (NCT01907347)
- Where
- 10 sites in Belgium, Brazil and 7 more
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Geneva
Critically Ill, Enterobacteriaceae Infections
Infections and Colonization With the Third Group of Enterobacteriaceae in the Intensive Care Unit
There is a lack of data whether colonization and infection with Enterobacteriaceae of the third group (EB3) affect the outcomes for ICU patients.
- Conditions
- Critically Ill, Enterobacteriaceae Infections, Antibiotic Resistant Infection
- Trial name
- EB3REA (NCT04528043)
- Where
- France
- Volunteers
- 179 people
- Sponsor
- Central Hospital, Nancy, France
Respiratory Syncytial Virus (RSV) Infection, Acute Lower Respiratory Tract Infections
Assessing the Burden of Respiratory Syncytial Virus (RSV)
This study examines the impact of Respiratory Syncytial Virus (RSV) on people of all ages, from infants to the elderly. It uses hospital records collected between January 2018 and December 2024 to understand: How often does RSV…
- Conditions
- Respiratory Syncytial Virus (RSV) Infection, Acute Lower Respiratory Tract Infections, Bronchiolitis, Pneumonia
- Trial name
- NCT07015255
- Where
- United Arab Emirates
- Volunteers
- 1,500 people
- Sponsor
- Abu Dhabi Health Services Company
Mortality, Intensive Care Unit
Effect of Favipiravir on Mortality in Patients With COVID-19 at a Tertiary Center Intensive Care Unit
Effect of Favipiravir and Lopinavir-Ritonavir on Mortality in a Tertiary Center Intensive Care Unit: Single Center Experience
- Trial name
- NCT04645433
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
ICU Patients Requiring Invasive Mechanical Ventilation
Study of a Strategy to Prevent Oversedation in Intensive Care Patients Under Mechanical Ventilation
The purpose of the present study is to determine whether administration of sedation according to a strategy including a bundle of measures to prevent oversedation is associated with a reduction in mortality of intensive care unit…
- Trial name
- AWARE (NCT01617265)
- Testing
- Clinical Procedure to Prevent Oversedation, Usual sedation practice
- Where
- 43 sites in France
- Volunteers
- 1,180 people
- Sponsor
- French Society for Intensive Care
Fluid and Electrolyte Imbalance, Anesthesia
BIA-Guided vs. Conventional Fluid Resuscitation in ICU Patients
In this study aimed to compare bioelectrical impedance analysis (BIA)-guided fluid resuscitation with conventional fluid management strategies in patients admitted to the intensive care unit (ICU) following major surgery.
- Trial name
- BIA-FLUID (NCT07142083)
- Testing
- Bioelectrical Impedance Analysis (BCM), Conventional Fluid Management
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ondokuz Mayıs University
AKI, Renal Replacement Therapy
Hyperoxia vs Normoxia During Cardiopulmonary Bypass
This single-center randomized controlled pilot trial evaluates the effects of intraoperative hyperoxia compared with normoxia during cardiopulmonary bypass (CPB) in adult patients undergoing elective cardiac surgery.
- Conditions
- AKI, Renal Replacement Therapy, NGAL, Arrythmia
- Trial name
- IPEROXIA (NCT07510672)
- Testing
- Hyperoxia group, Normoxia group (control)
- Where
- Italy
- Volunteers
- 104 people
- Sponsor
- University of Padova