Clinical trials: ICU Patients
Adult Disease, Intensive Care Unit Syndrome
Low-dose Dexmedetomidine in Mechanically Ventilated ICU Patients
For patients undergoing mechanical ventilation, light sedation is better than deep sedation for the outcomes, which is manifested as shortened length of ICU stay, shortened duration of mechanical ventilation, and decreased…
- Conditions
- Adult Disease, Intensive Care Unit Syndrome, Mechanical Ventilation Complication, Delirium
- Trial name
- NCT03172897
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Peking University First Hospital
Critical Illness, Mechanical Ventilation
Cost-Effectiveness of Inhaled Sedation Versus Intravenous Propofol in Mechanically Ventilated Critically Ill Adults
The goal of this observational study is to learn whether inhaled sedation is a cost-effective alternative to intravenous propofol in mechanically ventilated critically ill adults admitted to the intensive care unit.
- Conditions
- Critical Illness, Mechanical Ventilation, Respiratory Insufficiency
- Trial name
- NCT07734350
- Testing
- Isoflurane, Propofol (Astra-Zeneca)
- Volunteers
- 400 people
- Sponsor
- Hospital H+ Queretaro
Acute Respiratory Distress Syndrome, Prone Position
Early Verticalization of the Patient With Acute Respiratory Distress Syndrome: Assessment of Feasibility and Safety.
Acute Respiratory Distress Syndrome (ARDS) is defined according to the Berlin definition (1) as diffuse lung damage occurring in patients with a predisposing risk factor.
- Trial name
- STAND_ARDS1 (NCT04472260)
- Testing
- Verticalization and Prone position
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Sepsis
Project 4B: Lower Extremity Strength Training in ICU Patients
The purpose of this research study is to see if electrical stimulation of the leg muscles will improve strength in patients receiving mechanical ventilation in the intensive care unit (ICU).
- Trial name
- NCT02467023
- Testing
- Muscle stimulation with Niveus medical stimulator, measurement of maximal isometric twitch strength, Muscle Biopsy
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Florida
Septic Shock
Association Between Muscle L3 CT Scan Muscle Derived Parameters of Muscle Function Upon Intensive Care Unit Admission and 3 Months Mortality After ICU Discharge for Patients Admitted for Septic Shock. The SIMS Study
Muscle dysfunction in intensive care units is associated with significant morbidity and mortality. During septic shock, there is an increased catabolism and systemic inflammation resulting in quantitative and qualitative muscle…
- Trial name
- SIMS (NCT07483710)
- Testing
- Evaluation of muscle dysfunction in intensive care units for septic schock patients
- Where
- 4 sites in France
- Volunteers
- 196 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Weakness, Muscle
Bed Rest and Muscle Strength in ICU: Interest in the Early Association of NEMS With Cyclo-ergometer Mobilization
Muscles atrophy and weakness are common in intensive care units, their origin is multifactorial. Passive then active mobilization with cyclo-ergometer have shown to improve functional abilities and limit muscle weakness among…
- Trial name
- AFMPR (NCT03987997)
- Testing
- Early association of electrical muscle stimulation with cyclo-ergometer
- Where
- France
- Volunteers
- 55 people
- Sponsor
- Direction Centrale du Service de Santé des Armées
Enteral Nutrition, COVID-19 Acute Respiratory Distress Syndrome
Early Versus Delayed Enteral Nutrition in Critically Ill Adults With COVID-19
The goal of this observational study is to determine the relationship between the nutritional profile of critically ill patients diagnosed with COVID-19 and disease severity, prognosis, and survival, to assess the ability to meet…
- Trial name
- NCT06134674
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Ankara City Hospital Bilkent
Sepsis
Prognostic Impact of Admission Glucose Level in Septic Patients Admitted to the Intensive Care Unit
Background: Sepsis is one of the most common reasons for admission to intensive care units (ICU) worldwide. About 30% of all patients admitted to intensive care suffer from sepsis (1).
- Trial name
- NCT04740333
- Testing
- No intervention- observational study
- Where
- Israel
- Volunteers
- 224 people
- Sponsor
- Meir Medical Center
Acute Kidney Injury
Impact of a Treatment With Angiotensin Receptor Blocker on Outcome After Acute Kidney Injury in Patients Discharged From the ICU.
The patients discharged from intensive care units (ICU) have a high incidence of cardiovascular events and mortality rate during the year following ICU discharge.
- Trial name
- START-or-NOT (NCT05272878)
- Testing
- IRBESARTAN, tablet, 150 mg
- Where
- France
- Volunteers
- 508 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Corneal Perforation, Exposure Keratitis
The Role of OmniLenz® in the Treatment of Small Corneal Perforations Secondary to Exposure Keratitis in ICU Patients
Case series of 5 ICU patients in Farwaniya Hospital who developed exposure keratitis and a subsequent small corneal perforation between April 2022 and April 2024.
- Conditions
- Corneal Perforation, Exposure Keratitis, Infectious Keratitis
- Trial name
- NCT06539663
- Testing
- OmniLenz®
- Where
- Kuwait
- Volunteers
- 5 people
- Sponsor
- Farwaniya Hospital
Transfer Anxiety, Intensive Care Unit Discharge
Nurse-Led Transfer Program With Family Involvement to Reduce ICU Patient Anxiety
This study aims to evaluate whether including a patient's family member during transfer from the intensive care unit (ICU) to the general ward can help reduce anxiety in patients who have undergone cardiovascular surgery.
- Conditions
- Transfer Anxiety, Intensive Care Unit Discharge, Cardiac Surgery Recovery, Postoperative Anxiety
- Trial name
- FICARE-TX (NCT06979414)
- Testing
- Nurse-led Transfer Programme with Family Involvement
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Yakup Akyüz
Exercise, Intensive Care Unit Patients
Upper Extremity Theraband Exercises in Intensive Care Patients
Intensive Care Unit (ICU) is a special unit that deals with the diagnosis, treatment, and follow-up of patients who are in critical or severe condition and can not maintain their body balance.
- Trial name
- NCT06416540
- Testing
- Theraband Exercises plus Conventional Physiotherapy and Rehabilitation Program, Conventional Physiotherapy and Rehabilitation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Gastroparesis
Methylnaltrexone vs Erythromycin for Facilitating Gastric Emptying Time in Critically Ill Patients
42 patients admitted in ICU with intolerance to enteral feeding (GRV more than 250 ml) are recruited. All patients enter a primary acetaminophen absorption test study as baseline.
- Trial name
- NCT01117376
- Testing
- Erythromycin, Methylnaltrexone
- Where
- Iran
- Volunteers
- 42 people
- Sponsor
- Shiraz University of Medical Sciences
Intensive Care Unit, Inflammation
The New ICU Prognostic Score APACHE-INf
Intensive care units (ICUs) aim to provide specialized care for patients with high morbidity and mortality risks. To effectively identify patients requiring urgent diagnosis and treatment, various scoring systems have been…
- Conditions
- Intensive Care Unit, Inflammation, Nutritional Deficiency
- Trial name
- NCT05955547
- Testing
- Prognosis Scoring
- Where
- Turkey (Türkiye)
- Volunteers
- 15,000 people
- Sponsor
- Bursa City Hospital
Hyperdynamic, Left Ventricular Ejection Fraction
Hyperdynamic Left Ventricular Ejection Fraction as a Predictor of Mortality in Intensive Care Unit Patients With Septic Shock
The study aimed to evaluate the cause and prognosis of hyperdynamic left ventricular ejection fraction in critically ill patients with sepsis.
- Conditions
- Hyperdynamic, Left Ventricular Ejection Fraction, Mortality, Intensive Care Unit
- Trial name
- NCT06993948
- Testing
- Transthoracic echocardiography
- Where
- Egypt
- Volunteers
- 235 people
- Sponsor
- Ain Shams University
Post Covid-19 Patients
Active Cycle Of Breathing Technique Verses Breathing Exercises In Post ICU COVID-19 Patients
The experiment was randomized and controlled. To create groups A and B,48 individuals were selected by sample selection criteria.
- Trial name
- NCT05491876
- Testing
- Chest physiotherapy with breathing exercises and ACBT, Chest physiotherapy with breathing exercises
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University
Insulin Hypoglycemia, Glucose Test Site Bleeding
Blood Glucose Management in Intensive Care Units
The investigators propose to conduct a study of practices to describe the methods of managing glycemic control in hospitalized patients in critical care.
- Conditions
- Insulin Hypoglycemia, Glucose Test Site Bleeding, Hyperglycemia
- Trial name
- GINGER (NCT05775770)
- Testing
- Insulin
- Where
- France
- Volunteers
- 525 people
- Sponsor
- French Society for Intensive Care
Sepsis
Long-term Assessment of Patients Treated in the ICU for Sepsis
This study is a prospective, observational cohort clinical registry designed to describe clinical and epidemiological characteristics and outcomes of adult patients hospitalized with sepsis.
- Trial name
- LAPTUS (NCT07502794)
- Testing
- Usual Care
- Where
- Brazil
- Volunteers
- 760 people
- Sponsor
- Hospital Israelita Albert Einstein
Immersive Virtual Reality, Discomfort
Effect of a Virtual Reality Program on Patient Comfort in the Surgical Intensive Care Unit
Admission to a surgical intensive care unit (ICU) following major surgery is associated with a number of discomforts, not only related to the disease itself, but also to the care provided or the ICU environment itself (lights…
- Conditions
- Immersive Virtual Reality, Discomfort, IPREA, Intensive Care Unit
- Trial name
- ZION (NCT06830369)
- Testing
- HypnoVR, usual health care
- Where
- France
- Volunteers
- 194 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Conscious Sedation
Efficiency of Ventilation During Conscious Sedation in the Pediatric Intensive Care Unit
Pediatric patients admitted to the intensive care unit and requiring conscious sedation for minor surgical procedures are at risk to hypoventilate and retain CO2. The rise in CO2 levels is not well described and unpredicted.
- Trial name
- NCT01287572
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Tel-Aviv Sourasky Medical Center