Clinical trials: ICU Survivorship
Hyperglycemia, Critical Illness
Normoglycaemia in Intensive Care Evaluation and Survival Using Glucose Algorithm Regulation (NICE - SUGAR STUDY)
The primary aim of the study is to compare the effects of the two blood glucose targets on 90 day all-cause mortality in Intensive Care patients who are predicted on admission to stay in the ICU for at least one full calendar…
- Trial name
- NCT00220987
- Testing
- Intensive Insulin Therapy, Conventional Insulin therapy
- Where
- Australia
- Volunteers
- 6,104 people
- Sponsor
- The George Institute
Critical Illness, COVID-19 Pneumonia
Acute Kidney Injury in Coronavirus Disease-19 (COVID-19) Patients Admitted to the Intensive Care Unit (ICU)
The aim of this study is to evaluate the rate and outcomes of COVID-19 associated acute kidney injury (AKI) and use of kidney replacement therapy (KRT) in critically ill COVID-19 patients in ICUs in several large hospitals in…
- Conditions
- Critical Illness, COVID-19 Pneumonia, Acute Kidney Injury
- Trial name
- COVID-AKI-B (NCT04997915)
- Testing
- Observational study exploring the epidemiology and outcomes of AKI in critical COVID-19 patients admitted to the ICU
- Where
- 9 sites in Belgium
- Volunteers
- 1,286 people
- Sponsor
- University Hospital, Ghent
Covid19
COVID-19 Survivorship Registry
COVID-19 is associated with acute pulmonary and cardiac injury. To better understand the degree and severity of cardiopulmonary injury as well as short and long-term sequelae of COVID-19 infection, this study will perform…
- Trial name
- NCT04527315
- Testing
- Questionnaires
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Elderly, Surgery
Dexmedetomidine and Outcomes of Elderly Admitted to ICU After Surgery
Sleep disorder and delirium are common problems in intensive care unit (ICU) patients, and may lead to poor prognosis. The investigators' previous study showed that nighttime infusion of low-dose dexmedetomidine improved the…
- Conditions
- Elderly, Surgery, Intensive Care Unit, Dexmedetomidine
- Trial name
- NCT04204798
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 1,410 people
- Sponsor
- Peking University First Hospital
Ventilator-Associated Pneumonia (VAP), Central Line-Associated Bloodstream Infection
Impact of Nurses' Behavior Change and Evidence-Based Practice Implementation on Quality Indicators in Intensive Care Units in Low- and Middle-Income Countries
Study title: Impact of nurses' behavior change and implementing evidence-based practice to improve quality indicators in intensive care units in low-and middle-income countries Background and Rationale: Quality care is crucial…
- Conditions
- Ventilator-Associated Pneumonia (VAP), Central Line-Associated Bloodstream Infection, Pressure Ulcers (Hospital-acquired Pressure Injuries), Prolonged Intensive Care Unit Length of Stay
- Trial name
- NCT07397364
- Testing
- Evidence based practices bundles of care
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
ICU Mortality (Survival Rate)
FOUR-Based Modification of ICU Severity Scores
The goal of this observational study is to evaluate whether the Full Outline of UnResponsiveness (FOUR) score can replace the Glasgow Coma Scale (GCS) as the neurologic component of established intensive care unit (ICU) severity…
- Trial name
- FOUR-ICU (NCT07832773)
- Where
- Iraq
- Volunteers
- 2,000 people
- Sponsor
- Al-Nahrain University
COPD Exacerbation, ICU
Characteristics and Outcomes of Patients Admitted to ICU for a Severe Acute Exacerbation of COPD.
The objective of this prospective observational study is to describe the epidemiological, clinical and biological characteristics of patients admitted in ICU for a severe acute exacerbation of COPD, and to assess the different…
- Trial name
- COPDregister (NCT06257329)
- Testing
- register
- Where
- 4 sites in France
- Volunteers
- 2,000 people
- Sponsor
- Alexis FERRE
Covid19, Acute Respiratory Failure
Survival Rates and Longterm Outcomes After COVID-19
The study 'Survival rates and long-term outcomes for patients with COVID-19 admitted to Norwegian ICUs' is a national observational study, including patients admitted to a Norwegian ICU between March 2020 and March 2021.
- Conditions
- Covid19, Acute Respiratory Failure, Acute Respiratory Distress Syndrome, Post Intensive Care Unit Syndrome
- Trial name
- NCT04601090
- Testing
- ICU treatment
- Where
- Norway
- Volunteers
- 860 people
- Sponsor
- Oslo University Hospital
Acute Kidney Failure
Hannover Dialysis Outcome Study
Mortality rates of patients with acute kidney injury in the intensive care unit have changed little over the past few decades despite significant advances in supportive care.
- Trial name
- HAND-OUT (NCT00529139)
- Testing
- Standard extended dialysis, Intensified extended dialysis
- Where
- Germany
- Volunteers
- 157 people
- Sponsor
- Hannover Medical School
Esophageal Varicose Veins
Early TIPS in Real Life for Patient Admitted to Intensive Care Unit
Acute esophageal variceal bleeding (AEVB) is a serious complication of cirrhosis, with high morbidity and mortality. The latest European recommendations(1) recommend the early implementation, within 72 hours following esophageal…
- Trial name
- REALYTIPS (NCT04173299)
- Testing
- early tips
- Volunteers
- 100 people
- Sponsor
- Nantes University Hospital
Emergency Medical Services, Response
Response Times in Danish Emergency Medical Services
The overall aim of this retrospective observational study is to investigate the association of emergency medical services response time with patient survival and treatment outcomes.
- Conditions
- Emergency Medical Services, Response, Triage, Survival Outcomes
- Trial name
- AHRTEMIS (NCT06666647)
- Testing
- Treatment by ambulance or helicopter services with response times
- Where
- Denmark
- Volunteers
- 2,500,000 people
- Sponsor
- Peter Martin Hansen
Cognitive Rehabilitation, ICU Survivorship
Returning to Everyday Tasks Utilizing Rehabilitation Networks-III (RETURN-III)
Millions of patients survive care in medical and surgical Intensive Care Units (ICUs) every year, only to suffer from a new or accelerated dementia-like process, called post-ICU long-term cognitive impairment (ICU-LTCI).
- Conditions
- Cognitive Rehabilitation, ICU Survivorship, Intensive Care Unit, ICU
- Trial name
- RETURN-III (NCT04353804)
- Testing
- Treatment Arm: Computerized Cognitive Rehabilitation, Active Control computer games
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- VA Office of Research and Development
Polytrauma
Comparing Trauma Severity Scores Injury Severity Score "ISS", Rapid Emergency Medicine Score "REMS" and Kampala Trauma Score "KTS"
Trauma is defined as a physical injury from an external source of sudden onset and severity, which require immediate medical attention.Despite improvements in trauma systems worldwide, trauma continues to be one of the leading…
- Trial name
- NCT05544773
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Assiut University
Covid19, Hypoxic Respiratory Failure
SedAting With Volatile Anesthetics Critically Ill COVID-19 Patients in ICU: Effects On Ventilatory Parameters And Survival
Patients suffering lung failure, possibly from COVID-19 or hypoxic lung failure, will need life-saving support from a breathing machine.
- Trial name
- SAVE-ICU (NCT04415060)
- Testing
- Isoflurane Inhalant Product, Sevoflurane inhalant product
- Where
- 13 sites in Canada
- Volunteers
- 800 people
- Sponsor
- Sunnybrook Health Sciences Centre
Stress Disorders, Post-Traumatic
PTSD After ICU Survival - Caring for Patients With Traumatic Stress Sequelae Following Intensive Medical Care
During the PICTURE trial a short narrative therapy (narrative exposure therapy adapted for primary care) for patients with posttraumatic stress disorder (PTSD) after intensive care treatment is to be carried out by their general…
- Trial name
- PICTURE (NCT03315390)
- Testing
- "Narrative Exposure Therapy"-oriented intervention, improved treatment as usual (iTAU)
- Where
- 2 sites in Germany
- Volunteers
- 319 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Sepsis, Septic Shock
Early Goal-directed Therapy and Myocardial Dysfunction
The cardiovascular system plays a central role in the pathophysiology and prognosis of sepsis, yet the correct hemodynamic management of septic patients is still vigorously debated.
- Conditions
- Sepsis, Septic Shock, Myocardial Dysfunction
- Trial name
- SEPT-MD (NCT01312688)
- Testing
- Early Goal Directed Hemodynamic Therapy in Sepsis
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Hadassah Medical Organization
Survival
Adrenal Exhaustion Syndrome in Critically Ill Patients Without Improvement
We study the relationship between patient outcomes and sequential changes of serum cortisol level.
- Trial name
- NCT00674284
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Taiwan University Hospital
Burn Any Degree Involving 20-29 Percent of Body Surface, Burn Any Degree Involving 30-39 Percent of Body Surface
Predictive Mortality Scales in the Burn Patient Admitted to the Intensive Care Unit
The data for this retrospective study were collected from the records of patients admitted to the intensive care unit (ICU) for burns at Hospital La Paz from January 1, 2019 to May 31, 2023.
- Conditions
- Burn Any Degree Involving 20-29 Percent of Body Surface, Burn Any Degree Involving 30-39 Percent of Body Surface, Burn Any Degree Involving 40-49 Percent of Body Surface, Burn Any Degree Involving 50-59 Percent of Body Surface
- Trial name
- NCT07526610
- Where
- Spain
- Volunteers
- 465 people
- Sponsor
- Universidad Rey Juan Carlos
Aged, 80 and Over, Critical Care
Prognostic Score in the Very Old ICU Patients
The two main aims of the study: 1. To investigate the relation of Frailty, Activity of daily life (ADL), Cognitive functions and Co-morbidity on survival at 30 days (and 6 months in a substudy) 2.
- Trial name
- VIP2 (NCT03370692)
- Testing
- Cognitive assesment, Frailty assessment
- Where
- Norway
- Volunteers
- 3,900 people
- Sponsor
- University of Bergen
Mechanical Ventilation, Duration of Treatment
Ultrasound of Accessory Respiratory Muscles
The aim of this study is to compare the diameter of accessory respiratory muscles in patients with respiratory diseases and patients without such diseases, and to determine whether there is a connection between the…
- Conditions
- Mechanical Ventilation, Duration of Treatment, Survival
- Trial name
- NCT04519450
- Testing
- Mindray TE7 ultrasound machine
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- Osijek University Hospital