Clinical trials: IDIOPATHIC PARKINSON'S DISEASE
Idiopathic Parkinson Disease
Safety and Tolerability of Tozadenant as Adjunctive Therapy in Levodopa-Treated Patients With Parkinson's Disease.
Phase 3, international, multicenter, open-label 12 month safety study.
- Trial name
- NCT03051607
- Testing
- Tozadenant
- Where
- 35 sites in United States, Canada and 1 more
- Volunteers
- 66 people
- Sponsor
- Biotie Therapies Inc.
Idiopathic Parkinson's Disease
A Study to Assess the Effect of Safinamide on Levodopa Pharmacokinetics
The objective of this study is to investigate the effect of safinamide on levodopa blood levels, both after single and multiple dosing of safinamide .
- Trial name
- NCT01026428
- Testing
- Safinamide + Levodopa
- Where
- 2 sites in Italy
- Volunteers
- 24 people
- Sponsor
- Newron Pharmaceuticals SPA
Parkinson Disease, Idiopathic Parkinson Disease
Study to Determine Mutations in the Gaucher Gene in Patients With Idiopathic Parkinson's Disease for Phenotype-genotype Correlation
The genotype-phenotype correlation in patients with Parkinson's disease with specific mutations in the glucocerebrosidase gene (Gaucher gene) is known from own clinical experiences as well as from case reports in the literature.
- Trial name
- PadGau (NCT01272687)
- Where
- 15 sites in Germany, Thailand
- Volunteers
- 1,500 people
- Sponsor
- CENTOGENE GmbH Rostock
Idiopathic Parkinson's Disease
Efficacy and Safety Study of Inhaled CVT 301 in Parkinson's Disease Patients for Treatment of OFF Episodes
This randomized, multicenter, placebo-controlled, double-blind study will evaluate the efficacy and safety of inhaled CVT 301 compared with placebo in PD patients experiencing motor response fluctuations (OFF phenomena) as an…
- Trial name
- NCT01777555
- Testing
- CVT-301
- Where
- 22 sites in United States, Italy and 2 more
- Volunteers
- 89 people
- Sponsor
- Acorda Therapeutics
Parkinson Disease
Study of OXB-102 (AXO-Lenti-PD) in Patients With Bilateral, Idiopathic Parkinson's Disease
This study consists of two parts. Part A will evaluate the safety and tolerability of multiple doses of OXB-102 (AXO-Lenti-PD) in participants with Parkinson's disease.
- Trial name
- SUNRISE-PD (NCT03720418)
- Testing
- OXB-102, Imitation Surgical Procedure (ISP)
- Where
- 3 sites in France, United Kingdom
- Volunteers
- 6 people
- Sponsor
- Sio Gene Therapies
PD
A Clinical Study to Evaluate the Safety, and Tolerability of BBM-P002 in the Treatment of Parkinson's Disease
The purpose of the study is to evaluate the safety and tolerability of BBM-P002 for stereotactic injection to treat participants with idiopathic Parkinson's Disease (PD) during the dose-limiting toxicity (DLT) observation period.
- Trial name
- NCT07195825
- Testing
- Injecting BBM-P002 into the bilateral putamen
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Shanghai Xinzhi BioMed Co., Ltd.
Parkinson Disease, Idiopathic
MediPD: An Online Mediterranean Diet Program for People Living With Parkinson's Disease
The aim of this pilot study is to assess whether an online Mediterranean diet programme called MediPD is acceptable and practical for people living with Parkinson's disease, and whether it can help them make and maintain changes…
- Trial name
- MediPD (NCT07838675)
- Testing
- MediPD Online Mediterranean Diet Program
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- Queen's University, Belfast
Idiopathic Parkinson Disease, Telerehabilitation
Feasibility of Motor-cognitive Home Training for Parkinson's Disease Using eHealth Technology
The purpose of this study is to test the feasibility of a novel motor-cognitive home training intervention using eHealth technology among people with Parkinson's Disease
- Conditions
- Idiopathic Parkinson Disease, Telerehabilitation, Physical Therapy
- Trial name
- NCT05027620
- Testing
- Motor-cognitive exercise therapy in the home
- Where
- Sweden
- Volunteers
- 15 people
- Sponsor
- Stiftelsen Stockholms Sjukhem
Advanced Idiopathic Parkinson's Disease
Sleep Efficiency Assessed by Polysomnography (PSG Sleep Lab Testing) in Advanced Parkinson's Disease
This is a phase 4 study to evaluate with Polysomnography (PSG) and subjective measures the effect of Rotigotine on sleep efficiency, maintenance, insomnia, nocturnal akinesia and night-time movement in bed, in patients with…
- Trial name
- REFRESH-PD (NCT01519882)
- Testing
- Rotigotine
- Where
- United Kingdom
- Volunteers
- 1 people
- Sponsor
- UCB Pharma SA
Idiopathic Parkinson's Disease
Study of Liatermin (r-metHuGDNF) Administered by Bilateral Intraputaminal (IPu) Infusion to Subjects With Idiopathic Parkinson's Disease
This randomized study was designed to evaluate the efficacy and safety of IPu-infused liatermin (15mg/putamen/day) compared with placebo in subjects with symptomatic, levodopa-response Parkinson's disease.
- Trial name
- NCT00115427
- Testing
- Liatermin (r-metHuGDNF)
- Sponsor
- Amgen