Clinical trials: IMMUNONUTRITION
Nutritional Deficiency, Gynecologic Cancer
Immunonutrition in ERAS Protocols in Gynecologic Oncology
A patient with oncological pathology of any type because of impaired digestion and nutrient absorption, decreased intake, and increased nutrition requirements has an increased risk of malnutrition and moderate to severe weight…
- Conditions
- Nutritional Deficiency, Gynecologic Cancer, ERAS
- Trial name
- NUTRIGO (NCT06103526)
- Testing
- Immunonutrition
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- National and Kapodistrian University of Athens
Gastric Cancer, Colorectal Cancer
"The Impact of Immunonutrition on Gut Microbiota-related Aspects in Colorectal Cancer and Gastric Cancer Patients"
Enteral immunomodulating nutrition modifies the gastrointestinal microbiota as well as improves the intestinal barrier integrity in patients with gastric and colorectal cancer in the perioperative period.
- Trial name
- NCT04980950
- Testing
- Impact Oral Nestlé Health Science, Cubitan® Nutricia, Nutridrink® Nutricia, Resource 2.0 Nestlé Health Science
- Volunteers
- 80 people
- Sponsor
- Medical University of Gdansk
Immunonutrition, Gastric Cancer
Effect of Preoperative Immunonutrition in Upper Digestive Tract
Randomized, double-blind, multicenter clinical trial that will evaluate the effects of immuno-nutrition in the preoperative period in patients with cancer of the upper digestive tract (esophagus, stomach, and pancreas).
- Conditions
- Immunonutrition, Gastric Cancer, Esophageal Cancer, Pancreas Cancer
- Trial name
- NCT04027088
- Testing
- Immunonutrition, Standard
- Where
- 2 sites in Spain
- Volunteers
- 178 people
- Sponsor
- Complexo Hospitalario Universitario de A Coruña
Cancer of Colon, Nutrition Related Cancer
Preoperative Immunonutrition in Patients Undergoing Elective Colorectal Surgery for Neoplasm
Enhanced Recovery After Surgery (ERAS) protocols were developed to standardize perioperative practice in colon surgery to reduce morbidity, improve recovery, and shorten length of stay (LOS).
- Trial name
- NCT05916001
- Testing
- Oral Impact Nestle, Colorectal surgery
- Volunteers
- 216 people
- Sponsor
- University of Roma La Sapienza
Nutrition Poor
Evaluation of Immunonutrition For Patients With Pneumonia in the Intensive Care Unit.
The aim of the work will be to assess the combined effect of enteral or parenteral nutrition enriched with immunonutrition on the outcome of critically ill patients with pneumonia in comparison with patients who received standard…
- Trial name
- NCT05463458
- Testing
- nutrition
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Assiut University
Traumatic Brain Injury, Immuno-Deficiency
Effects of Immunonutrition on Biomarkers in Traumatic Brain Injury
Background: Head injury is one of the top three diagnosis leading to intensive care unit (ICU) admission in Malaysia. There has been growing interest in using immunonutrition as a mode of modulating the inflammatory response to…
- Conditions
- Traumatic Brain Injury, Immuno-Deficiency, Nutrient Deficiency
- Trial name
- NCT03166449
- Testing
- Neomune, Fresubin® HP energy
- Where
- Malaysia
- Volunteers
- 36 people
- Sponsor
- University of Malaya
General Surgery, Cancer of Colon
Preoperative High Protein vs Immunodiet in Surgical Cancer Patients
Immunomodulating nutrition is supposed to reduce the number of complications and the legnth of the hospital stay during the postoperative period in patients after major gastrointestinal surgery.
- Trial name
- Preop immuno (NCT03980704)
- Testing
- IMPACT, resource protein
- Where
- Poland
- Volunteers
- 299 people
- Sponsor
- Stanley Dudrick's Memorial Hospital
Esophageal Squamous Cell Carcinoma, Chemoradiotherapy
Whole-course Immunonutrition Combined With Chemoradiotherapy±ICIs for Local Advanced Patients With Inoperable Esophageal Squamous Cell Carcinoma
Chemoradiotherapy has been a standard modality for inoperable locally advance esophageal carcinoma. The goal of this randomized control study is to compare the feasibility, and survival benefits of whole-course immunonutrition…
- Conditions
- Esophageal Squamous Cell Carcinoma, Chemoradiotherapy, Immunonutrition, Inoperable
- Trial name
- NCT05833594
- Testing
- Whole-course Immunonutrition Combined With Chemoradiotherapy±ICIs
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Anhui Provincial Hospital
ColoRectal Cancer
Perioperative Immunonutrition in Colorectal Cancer Patients Undergoing Abdominal Surgery
The immune system plays an important role in helping to kill and prevent cancers. Cells of the immune system, such as natural killer (NK) cells and T cells, do not work as well following surgery.
- Trial name
- PERIOP-02 (NCT02987296)
- Testing
- Immunonutrition with arginine, Immunonutrition without Arginine
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Ottawa Hospital Research Institute
Colorectal Cancer
Impact of Immunonutrition on Nutritional Status in Colorectal Cancer Patients
Colorectal cancer is among the top three types of cancer that are most common and causes death worldwide.Nutritional support is widely used in elective colorectal surgery patients, as nutritional status is an important factor…
- Trial name
- NCT05568316
- Testing
- Preoperative Immunonutrition, Perioperative Immunonutrition
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Saglik Bilimleri Universitesi
Head and Neck Cancer, Nutrition
Immunonutrition Effects on Nutrition and Immunity in HNC During Radiotherapy
Head and neck cancer (HNC) is one of the most common types of malignant tumors, often leading to malnutrition due to its complex anatomical location near many functional organs.
- Trial name
- NCT07017218
- Testing
- IMPACT
- Volunteers
- 48 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Postoperative Complications, Pulmonary Complication
Perioperative Oral Decontamination and ImmunoNuTrition (POINT) in Elderly
The goal of this multicenter randomized controlled trial is to explore the efficacy of perioperative oral decontamination and immunonutrition supplement to prevent postoperative pulmonary complications in elderly patients(≥65…
- Trial name
- POINT (NCT05971810)
- Testing
- immunonutrition supplement of ORAL IMPACT™, oral chlorhexidine decontamination
- Where
- 2 sites in China
- Volunteers
- 592 people
- Sponsor
- Peking Union Medical College Hospital
Oral Mucositis
Benefits of Immunonutrition in Patients With Head and Neck Cancer Receiving Chemoradiation
This study evaluated the benefits of immunonutrition regarding the prevention of severe mucositis. Patients with head and neck cancer (HNC) undergoing definitive concurrent chemoradiation including 3-week cycles of cisplatin were…
- Trial name
- NCT05101889
- Testing
- Oral Impact®
- Volunteers
- 110 people
- Sponsor
- Prince of Songkla University
Arthroplasty, Hip Replacement, Perioperative Care
Immunonutrition in Total Hip Arthroplasty
The aim of this pilot study was to investigate whether the use of a multimodal protocol of preoperative care plus preoperative immune nutrition would decrease the length of stay and acute phase inflammation in patients submitted…
- Conditions
- Arthroplasty, Hip Replacement, Perioperative Care, Nutritional Support
- Trial name
- Immunehip (NCT02580214)
- Testing
- Impact
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Federal University of Mato Grosso
Peritoneal Metastases
Perioperative Immunonutrition for Patients Undergoing CRS and HIPEC
Patients with peritoneal disease commonly present with symptoms of abdominal distension and subacute intestinal obstruction. This results in poor oral intake leading to these patients often presenting in a malnourished state.
- Trial name
- NCT03430128
- Testing
- IMPACT immunotherapy, ENSURE
- Where
- Singapore
- Volunteers
- 70 people
- Sponsor
- National Cancer Centre, Singapore
Cystic Fibrosis, Malnutrition
Impact of Immunonutrition on the Patients With Cystic Fibrosis
The primary objectives: To evaluate the effect of immunonutrition on the adult patient suffering from cystic fibrosis 1. Safety of immunonutrition 2. The effect of immunonutrition on parameters of oxidative stress 3.
- Conditions
- Cystic Fibrosis, Malnutrition, Oxidative Stress
- Trial name
- NCT02048592
- Testing
- Impact-Nutridrink, Nutridrink-Impact
- Where
- Czechia
- Volunteers
- 30 people
- Sponsor
- University Hospital, Motol
Gastric Cancer, Gastric Adenocarcinoma
Frailty, Immunonutrition, Surgery Type, and Biologic Recovery in Elderly Gastric Cancer
This prospective observational cohort study will evaluate the effects of multidimensional frailty phenotypes, immunonutritional status, and surgical approach on biological recovery in patients aged 60 years and older undergoing…
- Trial name
- NCT07803159
- Testing
- Laparoscopic Gastrectomy, Open Gastrectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 328 people
- Sponsor
- Kocaeli City Hospital
Gastric Cancer, Surgery
Preoperative Immunonutrition in Laparoscopic Total D2 Gastrectomy
Immunonutrition (IN) appears to reduce infective complications and in-hospital length of stay (LOS) after gastrointestinal surgery. More specifically, it seems to be beneficial also in gastric cancer surgery.
- Conditions
- Gastric Cancer, Surgery, Laparoscopic, Gastric Neoplasm
- Trial name
- NCT05259488
- Testing
- immunonutrition
- Volunteers
- 51 people
- Sponsor
- University of Rome Tor Vergata
Colorectal Cancer, Nutrition Aspect of Cancer
Immunonutrition for Prehabilitation of Patients With Colorectal Cancer Before Surgery
Perioperative immunonutrition has been proposed as a strategy to modulate the inflammatory response and improve outcomes after colorectal surgery.
- Trial name
- IMNUTPREH-CRC (NCT07653737)
- Testing
- Oral nutritional supplement with inmmunonutrition, Standard oral nutritional supplement
- Where
- Spain
- Volunteers
- 56 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Stomach Neoplasms, Esophageal Neoplasms
Perioperative Nutrition in Upper Gastrointestinal (GI) Cancer Surgery
The aim of this study is to demonstrate the influence of peri-operative nutrition on the post-operative complications, preservation of lean body mass and length of stay after gastrectomy or oesophagectomy.
- Trial name
- NCT00560846
- Testing
- Impact, Glucose load
- Where
- Switzerland
- Volunteers
- 43 people
- Sponsor
- Dan Azagury