Clinical trials: IMMUNONUTRITION, open to volunteers
Head and Neck Cancer, Nutrition
Immunonutrition Effects on Nutrition and Immunity in HNC During Radiotherapy
Head and neck cancer (HNC) is one of the most common types of malignant tumors, often leading to malnutrition due to its complex anatomical location near many functional organs.
- Trial name
- NCT07017218
- Testing
- IMPACT
- Volunteers
- 48 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Cervical Cancers
The Effects of Immunonutrition Therapy on Locally Advanced Cervical Cancer Patients
The goal of this open-label randomized control trial is to study the effect of immunonutrition in locally advanced cervical cancer (LACC) with standard concurrent chemoradiotherapy.
- Trial name
- NCT06349148
- Testing
- enteral immunonutrition, standard oral enteral nutrition
- Where
- China
- Volunteers
- 50 people
- Sponsor
- SHUANG ZHENG JIA, PhD
Locally Advanced Nasopharyngeal Carcinoma
Effect of Immunonutrients on Oral Mucositis in Nasopharyngeal Carcinoma Patients After Chemoradiotherapy
The purpose of this study was to investigate the role of immunonutrion compared with standard nutrition in reducing oral mucositis in patients with locally advanced nasopharyngeal carcinoma.
- Trial name
- NCT05892354
- Testing
- Enteral immunonutrition, Standard enteral nutrition
- Where
- 20 sites in China
- Volunteers
- 190 people
- Sponsor
- First Affiliated Hospital of Guangxi Medical University
ERAS, Compliance
Pre-habilitation Within ERAS Protocol for Gynecologic Oncology Surgery: The Pre_ERAS Study
ERAS (Enhanced Recovery After Surgery) protocols are step-by-step care plans that help patients recover faster after surgery. They focus on keeping the body's normal functions, lowering stress from surgery, and supporting a…
- Conditions
- ERAS, Compliance, Quality of Life (QOL), Excercise
- Trial name
- Pre_ERAS (NCT07210164)
- Testing
- Ocoxin, Structured self-guided exercise
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Aristotle University Of Thessaloniki
Head and Neck Cancer
Immunonutrition and Tolerance to Chemoradiotherapy in Patients With Head-neck Cancer
The aim of the present project is to evaluate in a randomised, controlled, open-label, two parallel treatment groups pilot study, the efficacy of oral nutritional supplementation with a high-protein-high calorie mixture…
- Trial name
- NCT04611113
- Testing
- Immunonutrition, Control Nutritional Support
- Where
- Italy
- Volunteers
- 86 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Non Small Cell Lung Cancer, Small Cell Lung Cancer
Immunonutrition Reduces Acute Esophagitis After Thoracic Radiotherapy in Lung Cancer
This study aims to evaluate the efficacy of immunonutrition in reducing acute esophagitis after thoracic radiotherapy in lung cancer.
- Trial name
- Relief (NCT06840704)
- Testing
- Oral immunonutrition
- Where
- 6 sites in China
- Volunteers
- 121 people
- Sponsor
- Hunan Cancer Hospital
Fibromyalgia
Melatonin and Immunonutrition for Pain Relief in Fibromyalgia
Fibromyalgia (FMS) is characterized by chronic musculoskeletal pain, sleep disturbances, and fatigue. It is not entirely clear how Bcomplex vitamins affect the human pain system, while at the same time there have been approaches…
- Trial name
- NCT07863232
- Testing
- Melatonin 1mg and intravenous B-complex vitamin drip
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- University of Thessaly
Gastric Cancer, Immunonutrition
Oral Supplementation of Glutamine on Gastric Cancer Patients After Gastrectomy
Glutamine has the potentials of immunomodulation and adjustment of protein metabolism. The primary objective of this study is to evaluate the efficacy of glutamine on sarcopenia in gastric adenocarcinoma patients undergoing…
- Conditions
- Gastric Cancer, Immunonutrition, Gastrostomy
- Trial name
- NCT06027242
- Testing
- oral glutamine, Maltodextrin
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Lung Cancer, Nonsmall Cell
Immunonutrition for Improving the Efficacy of Immunotherapy in Patients With Metastatic Non-small Cell Lung Cancer
The present study was designed to evaluate the efficacy of the early systematic provision of oral nutritional supplements enriched in immunonutrients in non-small lung cancer patients undergoing immunotherapy and receiving…
- Trial name
- MURAL (NCT05384873)
- Testing
- Immunonutrition, Control dietary intervention
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Head and Neck Squamous Cell Carcinoma, Locally Advanced Rectal Cancer
GALENOS 1 in Head and Neck, Lung, and Rectal Cancer Patients
GALENOS 1 is a prospective observational study designed to explore longitudinal changes in nutritional status and body composition in patients with head and neck squamous cell carcinoma, locally advanced rectal cancer, and lung…
- Conditions
- Head and Neck Squamous Cell Carcinoma, Locally Advanced Rectal Cancer, Lung Cancer
- Trial name
- GALENOS 1 (NCT07511413)
- Where
- Italy
- Volunteers
- 110 people
- Sponsor
- Fondazione del Piemonte per l'Oncologia
Head and Neck Squamous Cell Carcinoma, Locally Advanced Rectal Cancer
Galenos 2 Immunonutrition in Head and Neck, Lung, and Rectal Cancer Patients
GALENOS 2 is a single-arm, single-center, phase II interventional study designed to evaluate the effects of a galenic immunonutrition dietary supplement in patients with head and neck squamous cell carcinoma, locally advanced…
- Conditions
- Head and Neck Squamous Cell Carcinoma, Locally Advanced Rectal Cancer, Lung Cancer
- Trial name
- GALENOS 2 (NCT07514754)
- Testing
- Galenic Immunonutrition Formula
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- Fondazione del Piemonte per l'Oncologia
Postoperative Delirium (POD), Gynecologic Cancers
Immunonutrition and Neuromonitoring for Postoperative Delirium in Gynecologic Oncology
Early postoperative delirium (POD) is a common and distressing neuropsychiatric complication frequently observed in elderly patients undergoing major surgical interventions, including radical and cytoreductive gynecologic…
- Conditions
- Postoperative Delirium (POD), Gynecologic Cancers, Malnutitrion
- Trial name
- NCT07877285
- Testing
- Preoperative Immunonutritional Scoring and Intraoperative Neuromonitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Bone Sarcoma, Soft Tissue Sarcoma
Preoperative Immunonutrition in Patients With Bone and Soft Tissue Sarcomas
This study will evaluate whether a short nutritional intervention before surgery can improve recovery in patients with bone and soft tissue sarcomas.
- Conditions
- Bone Sarcoma, Soft Tissue Sarcoma, Sarcopenia, Malnutrition
- Trial name
- NCT07609329
- Testing
- Forticare Advanced oral nutritional supplement
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Postoperative Complications
Perioperative Immunonutrition Intervention and Oral Decontamination in Elderly Surgical Patients
Elderly patients are vulnerable to postoperative complications. Preoperative malnutrition and poor oral hygiene are risk factors for postoperative complications especially pulmonary complications.
- Trial name
- NCT05679661
- Testing
- immunonutrition, oral chlorhexidine decontamination
- Where
- China
- Volunteers
- 590 people
- Sponsor
- Huang YuGuang
Esophageal Squamous Cell Carcinoma, Chemoradiotherapy
Whole-course Immunonutrition Combined With Chemoradiotherapy±ICIs for Local Advanced Patients With Inoperable Esophageal Squamous Cell Carcinoma
Chemoradiotherapy has been a standard modality for inoperable locally advance esophageal carcinoma. The goal of this randomized control study is to compare the feasibility, and survival benefits of whole-course immunonutrition…
- Conditions
- Esophageal Squamous Cell Carcinoma, Chemoradiotherapy, Immunonutrition, Inoperable
- Trial name
- NCT05833594
- Testing
- Whole-course Immunonutrition Combined With Chemoradiotherapy±ICIs
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Anhui Provincial Hospital
Nasopharyngeal Carcinoma (NPC)
Effect of Nutritional Management on Patients With Concurrent Chemoradiotherapy for Nasopharyngeal Carcinoma
Nasopharyngeal carcinoma (NPC) is a malignant tumor that develops in the nasopharyngeal mucosal epithelium. Due to the disease itself and the impact of anti-tumor therapy, malnutrition has become a common clinical complication in…
- Trial name
- NCT07085988
- Testing
- Rapid glitter
- Where
- China
- Volunteers
- 109 people
- Sponsor
- Jiangxi Provincial Cancer Hospital
Upper GI Cancer
Immunonutrition for Surgical Prehabilitation of Patients With Upper GI Cancer
Perioperative immunonutrition has been proposed as a strategy to modulate the inflammatory response and improve outcomes after upper GI surgery.
- Trial name
- IMNUTPREH-UGIC (NCT07884214)
- Testing
- Oral nutritional supplements with immunonutrition (enriched with arginine, nucleotides, vitamin D and omega-3-fatty acid), Standart of care
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Gastric Cancer, Gastric Adenocarcinoma
Frailty, Immunonutrition, Surgery Type, and Biologic Recovery in Elderly Gastric Cancer
This prospective observational cohort study will evaluate the effects of multidimensional frailty phenotypes, immunonutritional status, and surgical approach on biological recovery in patients aged 60 years and older undergoing…
- Trial name
- NCT07803159
- Testing
- Laparoscopic Gastrectomy, Open Gastrectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 328 people
- Sponsor
- Kocaeli City Hospital
Sepsis, Septic Shock
ICITRU : Randomized Trial of Immunonutrition With L-citrulline in Patients Hospitalized in Intensive Care for Sepsis or Septic Shock
Immunonutrition in intensive care has not yet demonstrated a beneficial effect on organ failure, the acquisition of nosocomial infections, or mortality.
- Trial name
- ICITRU (NCT04513288)
- Testing
- Experimental treatment L-citrulline (Protéocit®)
- Where
- 5 sites in France
- Volunteers
- 130 people
- Sponsor
- Rennes University Hospital
Bladder Cancer, Interstitial Cystitis
The Role of Preoperative Immunonutrition on Morbidity and Immune Response After Cystectomy (INCyst Trial)
The goal of this clinical trial research study is to evaluate the impact of preoperative oral immunonutrition (IN) on post-operative complications in patients undergoing a cystectomy.
- Conditions
- Bladder Cancer, Interstitial Cystitis, Painful Bladder Syndrome, Neurogenic Bladder
- Trial name
- INCyst (NCT05726786)
- Testing
- Immunonutrition
- Where
- 4 sites in Switzerland
- Volunteers
- 232 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois