Clinical trials: IMT
Frail Elderly Syndrome
Effects of WBV Associated With IMT on Functionality
The pre-frail elderly are a population more vulnerable to diminished functionality and future disabilities. Thus, interventions focused on the prevention of sarcopenia are indicated to prevent dysfunction in this population.
- Trial name
- NCT03688932
- Testing
- WBV + IMT
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Smokers
Acute IMT Intensity Effects in Male Smokers
Acute IMT Intensity Effects in Male Smokers
- Trial name
- NCT07200895
- Testing
- Inspiratory Muscle Training (30% MIP), Inspiratory Muscle Training (60% MIP)
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- FATMA DİLARA AKAR ÇAMYAR
Hyperlipidemias
Effect of Probucol and/or Cilostazol on Mean IMT in Patients With Coronary Heart dIsease
The purpose of this study is to evaluate the additional effect of probucol or concomitant administration of cilostazol and probucol on mean carotid artery intima-media thickness (mean IMT) at year 1, 2, and 3.
- Trial name
- IMPACTonIMT (NCT01291641)
- Testing
- HMG-CoA Reductase Inhibitor, Probucol, Cilostazol
- Where
- 5 sites in South Korea
- Volunteers
- 342 people
- Sponsor
- Seoul National University Hospital
Chronic Obstructive Pulmonary Disease
Effect of Inspiratory Muscle Training During PR on Dyspnoea and Exercise Tolerance in COPD Patients
Chronic obstructive pulmonary disease is a respiratory disease that results in progressive airflow limitation and respiratory distress.
- Trial name
- NCT04120142
- Testing
- Pulmonary rehabilitation+IMT, Pulmonary rehabilitation
- Where
- Tunisia
- Volunteers
- 34 people
- Sponsor
- Faculty of Medicine, Sousse
Healthy Young Adults
High vs Low Volume Intensity Training With IMT On Pulmonary Function And Breathing Efficiency On Recreational Swimmers.
This study aims to evaluate the impact of inspiratory muscle training (IMT) on respiratory function and swimming performance in competitive swimmers.
- Trial name
- NCT06604741
- Testing
- Assigned Interventions for LVIMT, Assigned interventions for HVIMT
- Where
- Pakistan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Riphah International University
FMD, IMT
Arterial Remodeling in Smokers
Cigarette smoking is the most important modifiable cardiovascular risk factor leading to endothelial dysfunction and was suggested to impair arterial regeneration.The aim of the study was to investigate the effect of smoking on…
- Conditions
- FMD, IMT, Smoking
- Trial name
- TCA (NCT01862146)
- Testing
- smoke expose
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Klinik für Kardiologie, Pneumologie und Angiologie
Chronic Obstructive Pulmonary Disease
Inspiratory Muscle Training During Pulmonary Rehabilitation in COPD
Demonstrate that IMT associated with a conventional pulmonary rehabilitation program allows a significant improvement of dyspnea in subjects with severe or very severe COPD than a conventional pulmonary rehabilitation program…
- Trial name
- EMI II (NCT02074813)
- Testing
- Inspiratory muscle training
- Where
- 2 sites in France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Brest
Weaning Failure
Improving Our Understanding of Respiratory Muscle Training to Facilitate Weaning From Mechanical Ventilation in the ICU
Mechanical ventilation is a life-saving treatment frequently applied in intensive care unit (ICU). Nonetheless, by putting at rest the respiratory muscles, it can lead to respiratory muscle weakness and atrophy, which are…
- Trial name
- TrainToWean (NCT04658498)
- Testing
- Procedure: Usual Care (UC), Procedure: UC + HI-IMT
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- KU Leuven
HIV Infections, Atherosclerosis
Antiretrovirals and Rate of Progression in Carotid Artery Intima-medial Thickness in HIV
It is well known that HIV-infected subjects frequently experience hyperlipidemias, insulin resistance, and visceral adiposity, which are known to increase the risk of atherosclerosis.
- Trial name
- NCT00575939
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Adenocarcinoma of the Esophagus, Adenocarcinoma of the Gastroesophageal Junction
Assessment of Metabolic & Path Response w/ RCT & ImT Before Surgery in Locally Advanced Esoph and Gastro-esoph Jction CA
ARTemIS-Eso is a phase I-II, three-level, open-label trial with a dose-expansion cohort at recommended schedule in both esophageal cancer histological groups (squamous cell carcinoma and adenocarcinoma) of RCT and ImT…
- Conditions
- Adenocarcinoma of the Esophagus, Adenocarcinoma of the Gastroesophageal Junction, Squamous Cell Carcinoma of the Esophagus
- Trial name
- ARTEMIS-Eso (NCT03307941)
- Testing
- Monalizumab, Oxaliplatin, 5-Fluorouracil
- Where
- Belgium
- Sponsor
- Jules Bordet Institute
Asthma
SERETIDE 100/50 bd (Twice Daily) Versus FLIXOTIDE 100 bd As Initial Maintenance Therapy In Moderate Asthma In Adults
This study will compare during 12 weeks, two treatment strategies for Initial Maintenance Therapy : fluticasone propionate alone or the salmeterol/fluticasone propionate combination in adults with moderate persistent asthma
- Trial name
- NCT00461500
- Testing
- Salmeterol xinafoate/fluticasone propionate combination, Fluticasone propionate
- Volunteers
- 81 people
- Sponsor
- GlaxoSmithKline
NSCLC, ALCL
Crizotinib Continuation Clinical Study
The purpose of this continuation study is to provide continued access to crizotinib treatment for eligible participants from a current Pfizer sponsored crizotinib clinical study that is planned to close.
- Conditions
- NSCLC, ALCL, IMT
- Trial name
- NCT05160922
- Testing
- crizotinib
- Where
- 13 sites in China, Italy and 3 more
- Volunteers
- 27 people
- Sponsor
- Pfizer
Qualitative Research
IMT in Asthma: Activity, Coping, Self-Management
The aim of this study is to investigate asthma patients' experiences with an 8 week IMT and the perceived effects of this intervention on physical activity, coping strategies, and asthma self-management.
- Trial name
- IMT in Asthma (NCT07320066)
- Testing
- other
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Istanbul Esenyurt University
PreDiabetes, Insulin Resistance
Disease Prevention in Clinical Practice Base on Patient Specific Physiology
It is well known that the Type 2 diabetes and vascular disease are preceded by over ten years by metabolic dysfunction and anatomic changes that can be quantified.
- Conditions
- PreDiabetes, Insulin Resistance, Type2 Diabetes, NASH - Nonalcoholic Steatohepatitis
- Trial name
- STOPDISEASE (NCT03308773)
- Testing
- Lifestyle modification in routine care of patients
- Volunteers
- 5,000 people
- Sponsor
- Pacific Coast Family Medical Group
Lung Transplantation
Impact of Inspiratory Muscle Training (IMT) With Intermittent Variable Resistance (IVR) Versus Constant Resistance (CR) on Functional Capacity in Lung Transplantation (LTx) Patients (I-TRAIN-LTx Study)
Objectives: Primary Objective: To compare Maximum Inspiratory Pressure (MIP) in lung transplant (LT) patients between the use of inspiratory muscle training (IMT) with intermittent variable resistance (IVR) or constant resistance…
- Trial name
- I-TRAIN-LTx (NCT06963190)
- Testing
- Constant Resistance (CR), Intermittent Variable Resistance (IVR)
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Hospital Universitario Marqués de Valdecilla
Chronic Obstructive Pulmonary Disease
Effect of Inspiratory Muscle Training During Pulmonary Rehabilitation on Balance in COPD Patients
Chronic obstructive pulmonary disease (COPD) is a respiratory disease that results in progressive airflow limitation and respiratory distress.
- Trial name
- NCT04084405
- Testing
- Pulmonary rehabilitation
- Where
- Tunisia
- Volunteers
- 35 people
- Sponsor
- Faculty of Medicine, Sousse
Age - Related Macular Degeneration (AMD)
International Study of the SING IMT™ Prosthesis in Pseudophakic patiEnts With Stable Moderate to Profound Bilateral Central vIsion Impairment Due to adVancEd AMD / PERSPECTIVE Study
This study aims to expand the CE mark IFU of the SING IMT™ to pseudophakic (patients with an intraocular lents) patients with late stage of AMD (Age-Related Macular Degeneration) and bilateral central vision impairment.
- Trial name
- PERSPECTIVE (NCT07164378)
- Testing
- Lens-Exchange, Add-on
- Where
- 12 sites in France, Germany and 1 more
- Volunteers
- 44 people
- Sponsor
- VisionCare, Inc.
Coronary Artery Occlusive Disease
The Effect of Carotid IMT (Intima Media Thickness) on Postoperative Cognitive Dysfunction in Patients Undergoing Off-Pump Coronary Artery Bypass Graft Surgery
The patients who have undergone cardiac surgery have higher likelihood of postoperative cognitive dysfunction (POCD). The carotid intima-media thickness (IMT) is associated with cognitive dysfunction in the old.
- Trial name
- NCT02456493
- Where
- South Korea
- Volunteers
- 224 people
- Sponsor
- Yonsei University
HIV Infections, Lipodystrophy
Observational Study of Changes in Fat Distribution and Blood Metabolites in HIV Infected Adults
The purpose of this study is to collect data on the body's breakdown of sugar and fat in HIV infected adults. Data from this study will make clearer the roles of HIV infection and anti-HIV drugs in the development of diabetes…
- Conditions
- HIV Infections, Lipodystrophy, Diabetes, Hyperlipidemia
- Trial name
- NCT00331448
- Volunteers
- 1,483 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Covid19
EFFECTS OF INSPIRATORY MUSCLE TRAINING IN POST-COVID-19 PATIENTS
COVID-19 is an infectious disease caused by the SARS-CoV-2 virus, which had its first case identified in December 2019 in Wuhan, China.
- Trial name
- NCT05493410
- Testing
- TREATMENT GROUP (TG), CONTROL GROUP (CG)
- Where
- 2 sites in Brazil
- Volunteers
- 42 people
- Sponsor
- University Vila Velha