Clinical trials: INTENSIVE CARE
Critical Illness, Respiratory Disease
UltraSound for Accurate Decisions in Chest PhysioTherapy
Introduction: Physiotherapist usually uses a clinical examination, including auscultation, an analysis of blood gasses and chest imaging to determine the indication for chest physiotherapy, to choose the treatment protocol and…
- Trial name
- US-ADEPT (NCT02881814)
- Testing
- Lung and diaphragm ultrasound, Lung and diaphragm ultrasound in MV patients
- Where
- 4 sites in Australia, France
- Volunteers
- 153 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Pulse Steroid and Immunoglobulins Drugs in Covid 19 Patients
Combined Use of Immunoglobulin and Pulse Steroid Therapies in Severe Covid-19 Patients
In December 2019, SARS-COV-2 was isolated from patients for the first time . It then rapidly turned into a pandemic affecting the whole world.While most Covid patients survive the disease with mild symptoms, some may develop…
- Trial name
- NCT06223984
- Testing
- pulse steroid and nanogam
- Where
- Turkey (Türkiye)
- Volunteers
- 178 people
- Sponsor
- Konya City Hospital
Weakness
Early Cycloergometric Physiotherapy in Critically Ill Patients With Invasive Mechanical Ventilation
Study designed to evaluate the functional and motor effects in critically ill subjects at ICU and hospital discharge with the incorporation of a mobilization program of cycloergometric physiotherapy sessions compared with…
- Trial name
- NCT02478411
- Testing
- Cycle ergometer physiotherapy, Conventional physiotherapy
- Where
- Spain
- Volunteers
- 68 people
- Sponsor
- Hospital Son Llatzer
Pressure Injury
Prevention to Pressure Injury With Care Bundle
Aim: The study was conducted in order to evaluate of pressure injury prevention care bundle application in intensive care unit patients diagnosed with internal diseases.
- Trial name
- NCT05541198
- Testing
- Pressure Injury Prevention Care Bundle
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people
- Sponsor
- Saglik Bilimleri Universitesi
Nephrectomy / Methods, Intraoperative Hypothermia
Effect of Preoperative Prewarming on Serum Lactate Levels in Patients Undergoing Elective Nephrectomy
The goal of this observational study is to learn whether warming patients before surgery, called "prewarming," affects blood lactate levels (a marker of how well tissues are getting oxygen) and recovery in adults having planned…
- Conditions
- Nephrectomy / Methods, Intraoperative Hypothermia, Hyperlactatemia
- Trial name
- NCT07702487
- Testing
- Preoperative active warming (prewarming)
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Beyzanur Aydoğdu
Medical Education, Simulation Training
Effectiveness of Simulation Based Training in Implementing One Hour Bundle Sepsis
This study aimed to compare simulation training with conventional training (case-based discussion only) to improve team performance in implementing one-hour sepsis bundle in the intensive care unit
- Conditions
- Medical Education, Simulation Training, Sepsis
- Trial name
- NCT05076721
- Testing
- Simulation training, Case-based discussion training
- Where
- Indonesia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Delirium, Agitation
A Comparison of Dexmedetomidine and Haloperidol in Patients With Intensive Care Unit (ICU)-Associated Agitation and Delirium
The purpose of the study is to determine whether dexmedetomidine is a more effective medication than haloperidol in the treatment of agitation and delirium in patients receiving mechanical ventilation in an intensive care unit.
- Conditions
- Delirium, Agitation, Ventilator Weaning, Respiration, Artificial
- Trial name
- Dex (NCT00505804)
- Testing
- dexmedetomidine, haloperidol
- Volunteers
- 20 people
- Sponsor
- Austin Health
Sedation
A Study Evaluating the Efficacy and Safety of HSK3486 for Sedation
This is a multi-center, open-label, randomized, propofol-controlled phase II clinical trial.A total of ICU patients undergoing mechanical ventilation are intended to be enrolled and randomly assigned to HSK3486 group and propofol…
- Trial name
- NCT04147416
- Testing
- HSK3486 0.1-0.2 /0.3 mg / kg group, Propofol 0.5-1.0/1.5 mg/kg group
- Where
- China
- Volunteers
- 39 people
- Sponsor
- Sichuan Haisco Pharmaceutical Group Co., Ltd
Morbidity, Multiple
Mortality in Paediatric Intensive Care
Mortality of paediatric patients in intensive care can be considered as on of the parameters of quality of care. Together with the advance in research and medicine there should be a trend towards mortality reduction, however…
- Trial name
- Paedmort (NCT03969355)
- Testing
- Mortality
- Where
- Czechia
- Volunteers
- 2,000 people
- Sponsor
- Brno University Hospital
Prolonged Sedation
Dexmedetomidine for Prolonged Sedation in PICUs
Sedation management of the critically ill patients is still a challenge for the pediatric intensivists. Worldwide the most common sedation approach includes the concomitant use of opioids and benzodiazepines.
- Trial name
- PROSDEX (NCT03760978)
- Testing
- Dexmedetomidine
- Where
- 9 sites in Italy
- Volunteers
- 163 people
- Sponsor
- Azienda Ospedaliera di Padova
Hypoglycemia, Neonatal Hypoglycemia
Effects of a Hypoglycemia Protocol With Glucose Gel on Neonatal Intensive Care Unit (NICU) Admission
Evaluate if the implementation of a hypoglycemia protocol with glucose gel has reduced the NICU admission rate of neonates with low-acuity neonatal hypoglycemia.
- Trial name
- NCT04085978
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Pediatrix
Intensive Care Nurses, Bacterial Colonization
Hand Hygiene Compliance and Bacterial Colonization on Personal Belongings
This study aims to examine whether intensive care nurses' hand hygiene practices are related to the presence and amount of bacteria on their frequently used personal belongings, such as mobile phones, pens, and identification…
- Conditions
- Intensive Care Nurses, Bacterial Colonization, Hand Hygiene Compliance
- Trial name
- HHC-BC (NCT07782385)
- Volunteers
- 57 people
- Sponsor
- Uludag University
ECMO Outcomes, Respiratory Failure (Pediatric Patients)
ECMO Use in Pediatric Oncology and HSCT Patients: A Descriptive and Comparative Analysis
This was an observational study, with a descriptive and comparative portion. The descriptive analysis, a large single center experience, examined bleeding complications, infectious rates, and survival outcomes in patients under…
- Conditions
- ECMO Outcomes, Respiratory Failure (Pediatric Patients), Malignancies, Hematologic, Solid Tumor Malignancies
- Trial name
- NCT07712835
- Testing
- Extracorporeal membrane oxygenation (ECMO)
- Volunteers
- 22 people
- Sponsor
- Children's Mercy Hospital Kansas City
Acute Kidney Injury
FURosemide Stress Test to Predict Need of Renal Replacement THERapy in Ischemic Acute Tubular Necrosis in ICU
Ischemic acute tubular necrosis (ATN) is one of the main cause of acute kidney injury (AKI) in intensive care units (ICU). Sepsis and cardio-pulmonary bypass (CPB) are major providers.
- Trial name
- FURTHER (NCT03731117)
- Testing
- Furosemide
- Where
- 3 sites in France
- Volunteers
- 11 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Critical Illness
Nutrition Practice in Critically Ill Adults
To determine the role of nutrition in recovery from critical illness, current practice must first be understood. However, no benchmarking process currently exists for nutrition practice during critical illness, from ICU admission…
- Trial name
- NUTRIENT (NCT06576895)
- Testing
- No intervention
- Where
- Australia
- Volunteers
- 600 people
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
VAP - Ventilator Associated Pneumonia
Microbiological Profile of VAP Patients in Respiratory ICU
Identification of the microbial profile of Ventilator associated pneumonia causing microorganisms among Respiratory ICU patients .
- Trial name
- VAP (NCT05738928)
- Testing
- blood and sputum culture
- Volunteers
- 86 people
- Sponsor
- Assiut University
Circadian Rhythm Sleep Disorder, Unspecified
Feasibility Pilot of Bright Light in the Intensive Care Unit
To evaluate the feasibility of providing daytime bright light in the ICU in a pilot randomized controlled trial.
- Trial name
- NCT03568045
- Testing
- standard light, 10,000 lux bright light, 4 hours, 10,000 lux bright light, 8 hours
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Yale University
Respiratory Insufficiency, Respiration, Artificial
Effects Of Invasive And Noninvasive Mechanical Ventilation On Sleep In The Intensive Care Unit (ICU)
The purpose of this study is to monitor sleep in patients using breathing machines, because little is known about sleep when patients use masks to help their breathing.
- Conditions
- Respiratory Insufficiency, Respiration, Artificial, Sleep Deprivation
- Trial name
- NCT00638339
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Tufts Medical Center
Covid19, Severe Acute Respiratory Syndrome
Ivermectin in Adults With Severe COVID-19.
Since the onset of the disease, more than 40.5 million people have been diagnosed with COVID-19 and nearly 1.2 million people have died (October 21, 2020).
- Trial name
- NCT04602507
- Testing
- Ivermectin
- Where
- Colombia
- Volunteers
- 75 people
- Sponsor
- CES University
Critical Illness, Muscle Weakness
Correlation Between Muscle Strength and Thickness in Critically Ill Patients
Mechanical ventilation (MV) is associated with adverse outcomes in ventilated patients, and impact of MV-induced diaphragm changes are still unclear.
- Trial name
- NCT06289244
- Testing
- Ultrasound, Muscle strength measurement
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico