Clinical trials: IOL
Cataract
Clinical Investigation of Expanded Designs of a Multifocal IOL
The purpose of this clinical trial is to evaluate the safety and effectiveness of the TECNIS Multifocal 1-Piece Intraocular Lens (IOLs), Models ZKB00 and ZLB00 which will each provide statistically better distance-corrected near…
- Trial name
- NCT01714635
- Testing
- Tecnis Multifocal Intraocular Lens, Monofocal Intraocular Lens
- Where
- 18 sites in United States, United Kingdom
- Volunteers
- 445 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Cataract, Astigmatism
Observational Prospective Clinical Investigation on Monofocal Toric Intraocular Lens
Evaluation, at least one-year long-term, of the clinical performance and safety of Mini Toric Ready Intraocular Lens (IOL), a monofocal toric intraocular lens.
- Trial name
- NCT06250855
- Testing
- Mini Toric IOL
- Where
- 2 sites in Romania
- Volunteers
- 105 people
- Sponsor
- SIFI SpA
Cataracts
AcrySof® IQ ReSTOR® +3.0 D Multifocal Toric Intraocular Lens (IOL) Clinical Study in Japan
The purpose of this study is to evaluate safety and effectiveness of AcrySof® IQ ReSTOR® +3.0 D Multifocal Toric IOL Models SND1T3, SND1T4, SND1T5, and SND1T6 when implanted to replace the natural lens in Japanese cataract…
- Trial name
- NCT01323777
- Testing
- AcrySof® IQ ReSTOR® +3.0 D Multifocal Toric IOL
- Where
- 2 sites in Japan
- Volunteers
- 65 people
- Sponsor
- Alcon Research
Cataract Senile
Evaluation of Glistening, Visual Outcomes and General Safety 24 Months Post-IOL Implantation
Main evaluation of glistening at least 24 Months post-IOL implantation
- Trial name
- NCT07297719
- Where
- China
- Volunteers
- 33 people
- Sponsor
- Carl Zeiss Meditec AG
Eye Diseases, Postcataract Aphakia
Investigation of the Safety and Effectiveness of Monofocal Toric Intraocular Lens (IOL)
This study is a prospective, multicenter, randomized, double masked trial comparing an investigational Monofocal Toric intraocular lens (IOL) (PODEYE TORIC CYL 1.5 D) and a commercially available non-toric monofocal IOL.
- Conditions
- Eye Diseases, Postcataract Aphakia, Cataract, Lens Opacities
- Trial name
- NCT06399211
- Testing
- PODEYE TORIC Monofocal IOL, Alcon AcrySof SA60AT Monofocal IOL
- Volunteers
- 261 people
- Sponsor
- Beaver-Visitec International, Inc.
Cataract, Lens Opacities
PMCF Study on Monofocal Toric IOL (PODEYE TORIC)
This is a single-center, prospective, open-label PMCF study whereby patients undergoing routine cataract surgery will have mono- or bilateral implantation of hydrophobic acrylic monofocal toric intraocular lens PODEYE TORIC…
- Conditions
- Cataract, Lens Opacities, Astigmatism
- Trial name
- PHY2101 (NCT04744467)
- Testing
- IOL implantation experimental
- Where
- Czechia
- Volunteers
- 12 people
- Sponsor
- Beaver-Visitec International, Inc.
Cataract
A-constant Optimization of a Toric Monofocal IOL
The study is a prospective series study to determine the IOL constant of a hydrophilic toric monofocal intra-ocular lens (IOL)
- Trial name
- NCT04944238
- Testing
- Ankoris
- Where
- Belgium
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Cataract, Ocular Hypertension
Evaluation of the Safety and Effectiveness of the Bimatoprost Implant System / IOL Combination in Patients With Ocular Hypertension or Mild to Moderate Open-angle Glaucoma
The goal of this clinical trial is to learn if the SpyGlass Pharma Bimatoprost Implant System / IOL Combination works to treat cataracts and either ocular hypertension or glaucoma.
- Conditions
- Cataract, Ocular Hypertension, Glaucoma
- Trial name
- NCT07154797
- Testing
- Bimatoprost Implant System / IOL Combination
- Where
- Honduras
- Volunteers
- 24 people
- Sponsor
- SpyGlass Pharma, Inc.
Aphakia, Postcataract, Cataract; Eye Disease
Safety and Efficacy of a Trifocal Intraocular Lens (IOL) POD L GF in Comparison With a Multifocal and a Monofocal IOL
The objectives of the Post-Market Follow-up (PMCF) clinical investigation are to determine the safety and performance of a hydrophobic trifocal intraocular lens POD L GF in comparison with two comparator lenses: another…
- Trial name
- NCT04005651
- Testing
- POD L GF IOL, Symfony® IOL, AcrySof® IOL
- Where
- 5 sites in France, Germany and 1 more
- Volunteers
- 100 people
- Sponsor
- Beaver-Visitec International, Inc.
Aphakia Cataract
Clinical Evaluation of the Adaptilens Accommodating IOL
The goals of this feasibility study are to learn more about the performance of the intraocular lens (IOL), if the IOL is safe for use, and what the best surgical techniques are for implanting the IOL in patients who require…
- Trial name
- NCT07607860
- Testing
- Accomodating Intra Ocular Lens, Monofocal Intra Ocular Lens
- Volunteers
- 100 people
- Sponsor
- Adaptilens, Inc.
Cataract, Glaucoma
Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhone)
This trial is a randomized study to evaluate the Bimatoprost Implant System used in combination with the SpyGlass IOL to Timolol Ophthalmic Solution in participants with mild to moderate open-angle glaucoma or ocular hypertension…
- Conditions
- Cataract, Glaucoma, Ocular Hypertension
- Trial name
- NCT07218796
- Testing
- Bimatoprost Implant System, SpyGlass IOL, Timolol Maleate Ophthalmic Solution, 0.5%
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- SpyGlass Pharma, Inc.
Cataract, Aphakia
Visual and Refractive Outcomes of The ClarVista HARMONI™ Modular Intraocular Lens System (HMIOL)
The purpose of this study was to evaluate visual and refractive outcomes with the use of the HARMONI™ Modular Intraocular Lens (HMIOL) System implantation, assembly, and optic exchange in subjects undergoing cataract surgery.
- Trial name
- NCT03681886
- Testing
- Harmoni Modular Intraocular Lens, Optic Exchange
- Volunteers
- 150 people
- Sponsor
- ClarVista Medical
Cataract
Visual and Refractive Outcomes After Implantation of Aspheric IOLs With Different Dioptric Increments and Manufacturing
This study compares two intraocular lenses, the Softec HD and the Tecnis Z9002, used to replace the natural crystalline lens after cataract extraction.
- Trial name
- NCT01249144
- Testing
- Intraocular Lens (IOL)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Lenstec Incorporated
Pseudophakia
Corrected VA With Long-Term Follow-Up After AcrySof® Intraocular Lens (IOL) Implantation
The purpose of this study is to compare the long-term visual acuity (VA) with an acrylic IOL to a silicone or polymethylmethacrylate (PMMA) IOL in cataract patients. This study will take place in Japan.
- Trial name
- NCT02450799
- Testing
- Acrylic IOL, Silicone IOL, PMMA IOL
- Volunteers
- 104 people
- Sponsor
- Alcon, a Novartis Company
Cataract
The Clareon PanOptix Trifocal IOL: Visual Outcomes and Patient Satisfaction
This will be a single arm, open-label, prospective study of patient-reported outcomes of patients with bilateral implantation of the Panoptix or Panoptix Toric implant.
- Trial name
- NCT05346172
- Testing
- PanOptix or PanOptix Toric IOL
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Research Insight LLC
Patients Having Undergone Unilateral Cataract Extraction and Implantation of a Monofocal
OPEN-LABEL, MULTI-CENTER, PHASE 1b/2a CLINICAL TRIAL DESIGNED TO EVALUATE THE SAFETY AND EFFICACY OF IONTOPHORETIC DEXAMETHASONE PHOSPHATE OPHTHALMIC SOLUTION IN PATIENTS HAVING UNDERGONE CATARACT SURGERY WITH IMPLANTATION OF A POSTERIOR CHAMBER INTRAOCULAR LENS (IOL)
To evaluate the safety and efficacy of ocular iontophoresis with dexamethasone phosphate ophthalmic solution, EGP-437®, using the EyeGate® II Drug Delivery System (EGDS) in patients having undergone cataract surgery with…
- Trial name
- NCT02571556
- Testing
- Experimental: Dexamethasone Phosphate Ophthalmic solution (40 mg/mL) delivered by ocular iontophoresis consisting of 4.0 mA-min at 1.5 mA
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Eyegate Pharmaceuticals, Inc.
Pseudoaphakia
Time Study for Biometry Measurements With the Lenstar and IntraOcularLens (IOL) Master 500
The objectives of this study are to determine the time needed to complete a full set of measurements (Total Ophthalmic Exam, Subject Data Entry and Acquisition of the Measurement) by each test device, the Lenstar 900 Version i4…
- Trial name
- NCT01550939
- Testing
- Ophthalmic Biometer
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Haag Streit USA
Cataract, Dry Eye
Efficacy of Topical Cyclosporine Versus Tears for Improving Visual Outcomes Following Multifocal IOL Implantation
The purpose of this study is to evaluate the efficacy on quality of vision and dry eye signs and symptoms in patients undergoing cataract surgery using the ReZoom® multifocal IOL.
- Trial name
- NCT00349583
- Testing
- Topical Cyclosporine, Tears
- Where
- United States
- Sponsor
- Innovative Medical
Cataract
Investigation of AcrySof® IQ PanOptix™ Presbyopia-Correcting Intraocular Lens (IOL) Model TFNT00
The purpose of this study is to investigate visual outcomes and assess safety at 12 months (330-420 days) post bilateral implantation of the AcrySof® IQ PanOptix™ Presbyopia-Correcting IOL.
- Trial name
- NCT02529488
- Testing
- AcrySof® IQ PanOptix™ Presbyopia-Correcting IOL
- Volunteers
- 167 people
- Sponsor
- Alcon Research
Cataract, Lens Opacities
PMCF Study on Monofocal Toric IOL (PODEYE TORIC) in Asia
This is a single-center, prospective, open-label PMCF study whereby patients undergoing routine cataract surgery will have mono- or bilateral implantation of hydrophobic acrylic monofocal toric intraocular lens PODEYE TORIC…
- Conditions
- Cataract, Lens Opacities, Astigmatism
- Trial name
- PHY2102 (NCT04778501)
- Testing
- IOL implantation experimental
- Where
- Philippines
- Volunteers
- 45 people
- Sponsor
- Beaver-Visitec International, Inc.