Clinical trials: IOL
Cataract
Longitudinal Changes in Refractive Error After Primary IOL Implantation Among Children With Congenital Cataract
The purpose of prospective cohort study is to estimate the rate of change in postoperative change after primary IOL implantation among children with congenital cataract(CC) and to explore key factors associated with the rate of…
- Trial name
- NCT04441268
- Testing
- primary IOL implantation
- Where
- China
- Volunteers
- 335 people
- Sponsor
- Sun Yat-sen University
Patients Having Undergone Unilateral Cataract Extraction and Implantation of a Monofocal
OPEN-LABEL, MULTI-CENTER, PHASE 1b/2a CLINICAL TRIAL DESIGNED TO EVALUATE THE SAFETY AND EFFICACY OF IONTOPHORETIC DEXAMETHASONE PHOSPHATE OPHTHALMIC SOLUTION IN PATIENTS HAVING UNDERGONE CATARACT SURGERY WITH IMPLANTATION OF A POSTERIOR CHAMBER INTRAOCULAR LENS (IOL)
To evaluate the safety and efficacy of ocular iontophoresis with dexamethasone phosphate ophthalmic solution, EGP-437®, using the EyeGate® II Drug Delivery System (EGDS) in patients having undergone cataract surgery with…
- Trial name
- NCT02571556
- Testing
- Experimental: Dexamethasone Phosphate Ophthalmic solution (40 mg/mL) delivered by ocular iontophoresis consisting of 4.0 mA-min at 1.5 mA
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Eyegate Pharmaceuticals, Inc.
Presbyopia, Near Vision
Level of Agreement Between Clinical Defocus Curves and the Web-based Democritus Digital Acuity Reading Test wDDART
The primary objective of this study is to compare the level of agreement between clinical defocus curves and the web Democritus Digital Acuity Reading Test (wDDART), which is a web-based digital near and intermediate vision…
- Trial name
- NCT04739085
- Testing
- Defocus curves - Monocular distance visual acuity with trial lenses added to the best correction for distance, wDDART - Monocular near visual acuity using the best correction for distance
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Democritus University of Thrace
Pseudoaphakia
Time Study for Biometry Measurements With the Lenstar and IntraOcularLens (IOL) Master 500
The objectives of this study are to determine the time needed to complete a full set of measurements (Total Ophthalmic Exam, Subject Data Entry and Acquisition of the Measurement) by each test device, the Lenstar 900 Version i4…
- Trial name
- NCT01550939
- Testing
- Ophthalmic Biometer
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Haag Streit USA
Refractive Assessment
Visual Performance After RESTOR Implantation
The purpose of this study is to evaluate the distance, intermediate, and near vision after aspheric multifocal diffractive AcrySof® ReSTOR SN6AD1 intraocular lens (IOL) implantation.
- Trial name
- NCT01065064
- Testing
- RESTOR IOL
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospital Oftalmologico de Brasilia
Cataract
Symfony vs Vivity in Dim Light
The purpose of this study is to evaluate the visual outcomes of the Symfony lens and the Vivity lens under mesopic lighting conditions in adult patients undergoing routine cataract surgery.
- Trial name
- NCT06229106
- Testing
- Symfony IOL, Vivity IOL
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- Carolina Eyecare Physicians, LLC
Cataract
Visual Acuity Outcome Differences Between the Alcon Vivity Toric IOL and RxSight LAL+
Phase 1 will be ambispective, multi-site, single arm study in age-related cataract patients with regular astigmatism, who were bilaterally treated with the LAL+ IOLs Phase 2 will be a prospective, randomized, unmasked…
- Trial name
- NCT06574646
- Testing
- LAL+, Clareon Vivity Toric IOL
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- The Eye Associates
Cataract
Clinical Investigation of the Bi Flex M Multifocal IOL
During cataract surgery an artificial lens is implanted in the eye. These artificial lenses are called intraocular lenses (IOLs) and there are many different types of IOL designs.
- Trial name
- NCT02338882
- Testing
- Bi flex M multifocal intraocular lens, Bi flex 1.8 monofocal intraocular lens
- Volunteers
- 100 people
- Sponsor
- Dr Phillip J Buckhurst
Cataract
Rotational Stability of Acrysof IQ Vivity Extended Vision Toric IOL and Refractive Visual Outcome.
The purpose of this research is to assess the rotational stability of the AcrySof IQ Vivity Extended Vision Toric IOL and Refractive Visual outcome.
- Trial name
- NCT05119127
- Testing
- Alcon Vivity toric intra ocular lens
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Kevin Barber
Cataract, Dry Eye
Efficacy of Topical Cyclosporine Versus Tears for Improving Visual Outcomes Following Multifocal IOL Implantation
The purpose of this study is to evaluate the efficacy on quality of vision and dry eye signs and symptoms in patients undergoing cataract surgery using the ReZoom® multifocal IOL.
- Trial name
- NCT00349583
- Testing
- Topical Cyclosporine, Tears
- Where
- United States
- Sponsor
- Innovative Medical
Cataract
Investigation of AcrySof® IQ PanOptix™ Presbyopia-Correcting Intraocular Lens (IOL) Model TFNT00
The purpose of this study is to investigate visual outcomes and assess safety at 12 months (330-420 days) post bilateral implantation of the AcrySof® IQ PanOptix™ Presbyopia-Correcting IOL.
- Trial name
- NCT02529488
- Testing
- AcrySof® IQ PanOptix™ Presbyopia-Correcting IOL
- Volunteers
- 167 people
- Sponsor
- Alcon Research
Intraocular Lens Dislocation, Aphakia - No Lens Capsule
Horizontal vs Vertical Scleral Tunnels in Flanged IOL Fixation
This study compares the 2-year outcomes of horizontal versus vertical scleral tunnel orientation in flanged intrascleral intraocular lens (IOL) fixation surgery.
- Trial name
- HORVER (NCT07701980)
- Testing
- Flanged Intrascleral IOL Fixation (Yamane Technique)
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people
- Sponsor
- Yuzuncu Yil University
Cataract
Trifocal Intraocular Lens (IOL) Aberrometry Outcomes
The goal of this study is to evaluate subject outcomes and spectacle independence with intraoperative aberrometry and trifocal IOL implantation.
- Trial name
- NCT04196569
- Testing
- Alcon Trifocal and Trifocal Toric Intraocular Lenses
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Weill Medical College of Cornell University
Cataract, Lens Opacities
PMCF Study on Monofocal Toric IOL (PODEYE TORIC) in Asia
This is a single-center, prospective, open-label PMCF study whereby patients undergoing routine cataract surgery will have mono- or bilateral implantation of hydrophobic acrylic monofocal toric intraocular lens PODEYE TORIC…
- Conditions
- Cataract, Lens Opacities, Astigmatism
- Trial name
- PHY2102 (NCT04778501)
- Testing
- IOL implantation experimental
- Where
- Philippines
- Volunteers
- 45 people
- Sponsor
- Beaver-Visitec International, Inc.
Myopia
Long Term Safety Protocol for the AcrySof CACHET Phakic Lens
The purpose of this long term safety study is to estimate the annualized endothelial cell loss (ECL) rate (for up to 10 years following date of implantation) of subjects previously implanted with the ACRYSOF CACHET Phakic…
- Trial name
- NCT01497067
- Testing
- ACRYSOF CACHET Phakic Lens (L-series)
- Where
- United States
- Volunteers
- 657 people
- Sponsor
- Alcon Research
Cataract
Clinical Investigation of Omega Refractive Capsule Model V With Use of an FDA Approved IOL
The objective of this study is to evaluate the safety and effectiveness of the investigational Omega Refractive Capsule (model V)
- Trial name
- ORCV (NCT04574102)
- Testing
- Omega Refractive Capsule with FDA approved Intraocular Lens, FDA approved Intraocular lens
- Where
- Costa Rica
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Omega Ophthalmics
Lenses, Intraocular Sensitivity
A Pilot Study Investigating the Impact of Different IOL Designs on Subjective 2D and 3D Image Quality
The WHO, states that age related cataracts account for 51 percent of worldwide blindness and affect about 20 million people. Surgery with intraocular lens (IOL) implantation is the first line treatment for cataracts, thus there…
- Conditions
- Lenses, Intraocular Sensitivity, Visual Acuity
- Trial name
- NCT02409641
- Testing
- Cyclopentolatehydrochloride 0,5% eye drops
- Where
- Austria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Aphakia, Corneal Astigmatism
Clinical Investigation of the Visual Outcomes and Safety of a Trifocal Toric IOL in an Asian Population
The purpose of this study is to evaluate the clinical performance of the ACRYSOF® IQ PanOptix® Toric Trifocal intraocular lens (IOL) when implanted in the eye following cataract removal in an Asian population.
- Trial name
- NCT04528069
- Testing
- ACRYSOF® IQ PanOptix® Toric Trifocal IOL, Cataract surgery
- Where
- 4 sites in Australia
- Volunteers
- 58 people
- Sponsor
- Alcon Research
Myopia, Myopic Astigmatism
Post-Market Evaluation of the EVO ICL
The objective of this study is to assess the rate of early intraocular pressure (IOP) increases following implantation of EVO/EVO+ Implantable Collamer Lens (ICL).
- Trial name
- NCT05538754
- Testing
- EVO ICL
- Where
- 8 sites in United States
- Volunteers
- 205 people
- Sponsor
- Staar Surgical Company
Childhood Cataract
Practical Pattern of Surgical Timing of Childhood Cataract in China
In the current study, the investigators analyzed the surgical RWD of 2,421 children with childhood cataracts from the Childhood Cataract Program of the Chinese Ministry of Health (CCPMOH) at the Zhognshan Ophthalmic Center and…
- Trial name
- NCT03640780
- Testing
- observation
- Where
- China
- Volunteers
- 2,421 people
- Sponsor
- Sun Yat-sen University