Clinical trials: IOL
Adult Grade III Lymphomatoid Granulomatosis, Adult Nasal Type Extranodal NK/T-cell Lymphoma
Brentuximab Vedotin + Rituximab as Frontline Therapy for Pts w/ CD30+ and/or EBV+ Lymphomas
The purpose of this study is to evaluate how safe and effective the combination of two different drugs (brentuximab vedotin and rituximab) is in patients with certain types of lymphoma.
- Conditions
- Adult Grade III Lymphomatoid Granulomatosis, Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma
- Trial name
- NCT01805037
- Testing
- brentuximab vedotin, rituximab, laboratory biomarker analysis
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Northwestern University
Lens Subluxation
Prospective Study of Cionni Ring and In-the-bag IOL Implantation for Subluxated Lenses
The purpose of this study is to report the intraoperative performance and postoperative outcomes of the Cionni-modified capsule tension ring implantation in eyes with subluxated lenses.
- Trial name
- NCT01346566
- Testing
- Cionni Modified Capsule Tension Ring
- Where
- India
- Volunteers
- 33 people
- Sponsor
- Iladevi Cataract and IOL Research Center
Cataract, Lens Opacities
Visual Performance Intraocular Lens (IOL) MicroPure 1.2.3.
The clinical investigation is a post-market clinical follow up study whereby patients undergoing routine cataract surgery will have monolateral implantation of a commercially available, CE approved monofocal intraocular lens…
- Trial name
- NCT03297372
- Testing
- IOL implantation
- Where
- 2 sites in Italy
- Volunteers
- 121 people
- Sponsor
- Beaver-Visitec International, Inc.
Adult Grade III Lymphomatoid Granulomatosis, Anaplastic Large Cell Lymphoma
PXD101 and Bortezomib in Treating Patients With Advanced Solid Tumors or Lymphomas
This phase I trial is studying the side effects and best dose of PXD101 and bortezomib in treating patients with advanced solid tumors or lymphomas.
- Conditions
- Adult Grade III Lymphomatoid Granulomatosis, Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma, Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue
- Trial name
- NCT00348985
- Testing
- belinostat, bortezomib, pharmacological study
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- National Cancer Institute (NCI)
Myopia, Myopic Astigmatism
Multicenter Clinical Trial of a Phakic Implantable Collamer® Lens (ICL)
This objective of this study is to evaluate the safety, and to collect supportive data on effectiveness of the EVO/EVO+ Visian® Implantable Collamer® Lens (ICL) in study participants who have a diagnosis of myopia or myopia with…
- Trial name
- NCT04283149
- Testing
- EVO/EVO+ Visian ICL
- Where
- 14 sites in United States
- Volunteers
- 327 people
- Sponsor
- Staar Surgical Company
Outcomes Following Restor IOL Lens Implant
Clinical Outcomes After AcrySof® ReStor IOL Surgery in Faculty Practice at UTSW Medical Center at Dallas: A Retrospective Review
To evaluate the clinical outcomes of AcrySof® ReSTOR® IOL for the Faculty Practice at UTSW Medical Center at Dallas
- Trial name
- NCT00344578
- Testing
- Restor IOL
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Lens Luxation, IOL Subluxation
Long-term Results of Two Surgical Methods for Scleral IOL Implantation and Fixation in Eyes Without Capsular Support: Yamane- Versus 4-flanged Technique
This study is a comparison of the surgical techniques and postoperative outcome between the two intrascleral IOL fixation techniques: Yamane technique versus the 4-flanged technique.
- Conditions
- Lens Luxation, IOL Subluxation, IOL Opacification, Aphakia - No Lens Capsule
- Trial name
- YAMPOINT (NCT06102109)
- Testing
- Pars plana vitrectomy, IOL explantation, Scleral IOL fixation Yamane Technique
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Medical University of Vienna
Cataract
Evaluation the TECNIS IOL in Both Eyes VS the ReZoom IOL in One and TECNIS IOL in the Opposite
The purpose of this study is to evaluate the visual performance of two cohorts of patients who received multifocal intraocular lenses following cataract and clear lens extraction surgeries.
- Trial name
- NCT01253239
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Frank A. Bucci, Jr., M.D.
Patient Satisfaction
Patient Satisfaction in Post-LASIK Patients With Presbyopia-Correcting IOLs vs. Post-Lasik Patients With Monofocal IOLs
Compare functional visual outcomes and patient satisfaction of post-LASIK patients having received presbyopia-correcting IOLs versus post-LASIK patients having received monofocal IOLs
- Trial name
- NCT04134507
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Bucci Laser Vision Institute
B-cell Adult Acute Lymphoblastic Leukemia, B-cell Childhood Acute Lymphoblastic Leukemia
Rituximab in Treating Patients Undergoing Donor Peripheral Blood Stem Cell Transplant for Relapsed or Refractory B-cell Lymphoma
This phase II trial studies giving rituximab before and after a donor peripheral blood stem cell transplant in patients with B-cell lymphoma that does not respond to treatment (refractory) or has come back after a period of…
- Conditions
- B-cell Adult Acute Lymphoblastic Leukemia, B-cell Childhood Acute Lymphoblastic Leukemia, B-cell Chronic Lymphocytic Leukemia, Childhood Burkitt Lymphoma
- Trial name
- NCT00867529
- Testing
- rituximab, peripheral blood stem cell transplantation, nonmyeloablative allogeneic hematopoietic stem cell transplantation
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Fred Hutchinson Cancer Center
Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders
Personalized Information or Basic Information in Helping Patients Make Decisions About Participating in a Clinical Trial
RATIONALE: Providing information that is tailored to answer patients' questions about clinical trials may help patients with cancer decide to enroll in a clinical trial.
- Conditions
- Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders, Leukemia, Lymphoma
- Trial name
- NCT00750009
- Testing
- educational intervention
- Where
- 4 sites in United States
- Volunteers
- 583 people
- Sponsor
- Case Comprehensive Cancer Center
Primary Open Angle Glaucoma, Glaucoma, Open Angle, Pseudo-exfoliative
Safety and Efficacy Trial to Evaluate the Hydrus(TM) Implant in Subjects Undergoing Cataract Surgery.
The objective of this study is to demonstrate the ability of the Hydrus Implant to lower intraocular pressure in glaucoma patients undergoing cataract surgery.
- Conditions
- Primary Open Angle Glaucoma, Glaucoma, Open Angle, Pseudo-exfoliative, Cataract Unilateral Pending Extraction
- Trial name
- Hydrus II (NCT01818115)
- Testing
- Hydrus Implant, IOL placement
- Where
- 7 sites in Germany, Italy and 2 more
- Volunteers
- 100 people
- Sponsor
- Ivantis, Inc.
Cataracts, Cataract Surgery
Endothelial Cell Loss and Induced Astigmatism After Wound-directed and Wound-assisted IOL Injection
The purpose of this study is to determine if there is any difference in astigmatism (eye surface curvature) or corneal endothelial cell density (the inner cell lining of the eye surface) after two different methods for inserting…
- Trial name
- NCT01250964
- Testing
- Lens insertion during cataract surgery
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of North Carolina, Chapel Hill
Cancer
Laboratory Assay in Determining Cancer Resistance in Patients With Metastatic Cancer and in Healthy Participants
RATIONALE: Studying samples of blood and tissue in the laboratory from patients with cancer and from healthy participants may help doctors learn more about cancer.
- Trial name
- NCT00899496
- Testing
- immunological diagnostic method, physiologic testing
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Lens Implantation, Intraocular
Incidence of Glaucoma-related Adverse Events in Pediatric Secondary Intraocular Lens Implantation
To compare the incidence of glaucoma-related adverse events of in-the-bag versus ciliary-sulcus-fixed secondary intraocular lens (IOL) implantation in pediatric aphakia
- Trial name
- NCT05136950
- Testing
- Secondary in-the-bag IOL fixation, Secondary ciliary sulcus IOL fixation
- Where
- China
- Volunteers
- 228 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders
3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With Cancer
RATIONALE: Diagnostic procedures, such as 3'-deoxy-3'-[18F] fluorothymidine (FLT) PET imaging, may help find and diagnose cancer.
- Conditions
- Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders, Leukemia, Lymphoma
- Trial name
- NCT00935090
- Testing
- 3'-deoxy-3'-[18F]fluorothymidine
- Where
- United States
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Cataract
Safety and Effectiveness of the Opira AIOL in Comparison to Commercial IOLs in Patients Undergoing Cataract Surgery
This is a clinical trial comparing an investigative accommodative IOL and two commercial IOLs in patients with cataracts undergoing primary cataract surgery.
- Trial name
- NCT04756908
- Testing
- Cataract Surgery
- Where
- 2 sites in Costa Rica, Mexico
- Volunteers
- 200 people
- Sponsor
- FSV6, Ltd.
Cataract
PureSee/Odyssey Mix-and-Match IOL
Observational, prospective, bilateral, single-arm investigator-initiated study. Single cohort at one site: TECNIS PureSee intraocular lens in the dominant eye and TECNIS Odyssey intraocular lens in the non-dominant eye.
- Trial name
- NCT07898917
- Testing
- Mix-and-match PureSee/Odyssey cohort
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Gainesville Eye Associates
Posterior Capsule Opacification, Postoperative Complications
Clinical Trial : Complications of in the Bag IOL Versus Optic Capture of IOL in Pediatric Cataract Surgery
This prospective, randomized, clinical trial looks to compare children undergoing congenital cataract surgery with intraocular lens (IOL) implantation in terms of visual axis obscuration as well as postoperative complications…
- Trial name
- NCT02491918
- Testing
- cataract surgery, Intraocular lens implantation
- Volunteers
- 61 people
- Sponsor
- Iladevi Cataract and IOL Research Center
Cataract
Observation of Rotation of an Intraocular Lens
The purpose of this study is to assess the axial IOL rotation after surgery with an MC 6125 AS IOL. At the end of surgery the orientation of the IOL is documented with a short video clip via the operating microscope unit.
- Trial name
- NCT02208232
- Testing
- cataract surgery
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Medical University of Vienna