Clinical trials: IOP
Intraocular Pressure
iCare IC1000 Alignment Study
The primary objective of this study is to evaluate the performance of the alignment feature of iCare IC1000 tonometer.
- Trial name
- NCT07022054
- Testing
- iCare IC1000 measurement
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Icare Finland Oy
Healthy Subjects
SENSIMED Triggerfish® in Sitting and Supine Position
The purpose of the study is to evaluate changes in intraocular pressure (IOP) between sitting and supine body positions and correlate the values obtained with conventional tonometers to the output provided by the investigational…
- Trial name
- NCT01347229
- Testing
- SENSIMED Triggerfish®
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sensimed AG
Safety and Tolerability of SENSIMED Triggerfish in Glaucoma Patients
SENSIMED Triggerfish Discomfort During IOP Monitoring
Evaluation of the wearing discomfort (safety and tolerability) involved during IOP monitoring with the SENISMED Triggerfish, a sensor embedded in a telemetric contact lens
- Trial name
- 09/02 (NCT00966108)
- Testing
- SENSIMED Triggerfish
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sensimed AG
Primary Open Angle Glaucoma (POAG)
One, Two, or Three iStents for the Reduction of Intraocular Pressure in Open-angle Glaucoma Subjects
The purpose of this study is to evaluate the safety and efficacy of the intraocular pressure (IOP) lowering effect of one, two, or three iStent devices in eyes of subjects previously on two anti-glaucoma medications.
- Trial name
- NCT01517477
- Testing
- iStent
- Where
- Armenia
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Glaukos Corporation
Intraocular Pressure, Glaucoma
Comparison of Intraocular Pressure Measurements Between Reichert Tono-Vera Tonometer and Goldmann Tonometry
Determine if the Tono-Vera Tonometer accurately measures intraocular pressure (IOP). The hypothesis of this test is to confirm the Tono-Vera Tonometer is equivalent to the Goldmann Applanation Tonometer (within +/- 5.0 mmHg).
- Trial name
- NCT04360369
- Testing
- IOP with Goldmann Applanation Tonometer, IOP with comparator ORA G3 and ic100 tonometers, IOP with Tono-Vera Tonometer
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Reichert, Inc.
Glaucoma, Ocular Hypertension
This Follow-up Extension Study is Aimed to Monitor the Long-term IOP-lowering Performance/Efficacy and Safety of the MINT® Procedure in Open Angle Glaucoma Eyes.
This follow-up extension study is planned to invite all patients who underwent the MINT® surgery and completed Month 24 Visit in the prior MMS EEU-7 study.
- Conditions
- Glaucoma, Ocular Hypertension, Open-Angle Glaucoma
- Trial name
- NCT07081347
- Testing
- MINT Minimally Invasive Nasal Trabeculostomy
- Where
- Armenia
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Sanoculis Ltd
Magnetic Resonance Imaging
Phase Ib, Administration the IOP Injection for MRI Contrast Agent in Healthy Subjects
The objective of the study is to assess the dose dependent changes in MRI signal intensity (SI) in liver after IOP Injection intravenous administration in healthy volunteers.
- Trial name
- NCT03399214
- Testing
- IOP Injection
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- MegaPro Biomedical Co. Ltd.
Intraocular Pressure
Clinical Validation of iCare IC1000 Tonometer
Clinical validation of iCare IC1000 tonometer per ANSI Z80.10:2014 standard
- Trial name
- NCT06748092
- Testing
- iCare IC1000, iCare IC200, GAT
- Where
- Canada
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Icare Finland Oy
Intraocular Pressure
Comparative Study of the Topcon Tonometers CT-800 and TRK-2P and the Haag-Streit Goldmann Manual Tonometer and Topcon SP-1P
The study will assess the CT-800 and TRK-2P for conformity to ANSI Z80.10-2014 Ophthalmic Instruments - Tonometers, to the FDA Guidance for Industry and FDA Staff, Tonometer-Premarket Notification [510(k)] Submissions, and to the…
- Trial name
- NCT03439774
- Testing
- Topcon CT-800, Topcon TRK-2P
- Where
- United States
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- Topcon Medical Systems, Inc.
Glaucoma; Drugs
CATS Tonometer IOP Reduction Latanoprost Verses Timolol
Topical Prostaglandin Analog vs Betablocker - Corneal Biomechanical Evaluation using CATS Tonometer Prism
- Trial name
- NCT04178863
- Testing
- CATS Tonometer, Latanoprost
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Intuor Technologies, Inc.
Healthy Subject
24-hour IOP Pattern With SENSIMED Triggerfish® in a Healthy Population
A database (Snapfish) has been generated at Sensimed compiling all data acquired up to now on healthy volunteers and patients with glaucoma. However, healthy subjects were much younger than glaucoma patients.
- Trial name
- NCT01906502
- Testing
- Sensimed Triggerfish
- Where
- 5 sites in Israel
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Sensimed AG
Intraocular Pressure, Corneal Pachymetry
Comparative Study of Non-contact Tonometers for Intraocular Pressure and Corneal Cell Thickness Measurements
The primary objective of this clinical study is to collect clinical data to support FDA 510(k) submissions for the Topcon CT-800, CT-1, CT-1P and TRK-2P non-contact tonometers.
- Trial name
- NCT02138279
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Topcon Medical Systems, Inc.
Glaucoma, GLAUCOMA 1, OPEN ANGLE, D (Disorder)
24-hour Wear Performance and Safety Study of Smartlens miLens Contact Lens for IOP Monitoring
The goal of this clinical trial is to learn if a new contact lens device can record patterns in eye pressure for 24 hours in adults with glaucoma and in healthy participants.
- Conditions
- Glaucoma, GLAUCOMA 1, OPEN ANGLE, D (Disorder), Ocular Hypertension, Ocular Hypertension (OH)
- Trial name
- NCT06689696
- Testing
- miLens system
- Where
- 3 sites in United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Smartlens, Inc.
Intraocular Pressure
Icare Versus Haag-Streit Applanation Tonometer
The clinical performance of Icare ONE Tonometer TA02 was compared to a Goldmann type applanation tonometer (Haag-Streit). Data was collected according to ANSI Z80.10-2003 (ISO 8612.2) standard.
- Trial name
- NCT01159340
- Where
- Finland
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Icare Finland Oy
Intraocular Pressure
Efficacy of Latanoprostene Bunod in Lowering Intraocular Pressure in Japanese Healthy Male Volunteers
The objective of this study is to evaluate the effect of latanoprostene bunod dosed once daily (QD) in reducing intraocular pressure (IOP) measured over a 24-hour period in healthy subjects.
- Trial name
- KRONUS (NCT01895985)
- Testing
- Latanoprostene bunod
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Depressive Disorder
A Study To Evaluate The Effect Of WELLBUTRIN XL On Intraocular Pressure
This study will be conducted in healthy volunteers to investigate the effect on intraocular pressure of 2 weeks of treatment with 300mg WELLBUTRIN XL/day.
- Trial name
- NCT00439868
- Testing
- WellbutrinXL
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Intraocular Pressure
Quick Measure Study for iCare ST500 and iCare IC200
The aim of this clinical study is to compare the agreement and precision of the intraocular pressure (IOP) results measured with the Quick Measure feature of iCare ST500 and iCare IC200 tonometers with results obtained with…
- Trial name
- NCT07156630
- Testing
- iCare ST500, iCare IC200, GAT
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Icare Finland Oy
Intraocular Pressure
Intraocular Pressure Data Collection With Tonometers
The goal of this clinical trial is to collect a comprehensive dataset of intraocular pressure values for developing a measurement algorithm for the new hand-held rebound tonometer device.
- Trial name
- NCT06450587
- Testing
- iCare IC1000, iCare ST500, iCare IC200
- Where
- 2 sites in Slovenia
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Icare Finland Oy
Intraocular Pressure
Clinical Study for TONOREF III Tested to ANSI Z80.10-2014
The primary objective of this clinical study was to show that tonometry values for TONOREF III, as the representative device of the NIDEK tonometer series, were comparable to the predicate device.
- Trial name
- NCT07152808
- Testing
- NIDEK TONOREF III, Haag-Streit Goldmann Manual Tonometer
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Nidek Co. LTD.
Intraocular Pressure
Eyenovia MiDD Usability Study
This study is to evaluate the usability and patient tolerability for microtherapeutic dosing of commercially available ocular medication via the Eyenovia microdose delivery system (MiDD)
- Trial name
- NCT03480906
- Testing
- Latanoprost
- Where
- Panama
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Eyenovia Inc.