Clinical trials: IPMN
Chronic Pancreatitis, Inflammatory Bowel Diseases
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in the medical literature affect…
- Conditions
- Chronic Pancreatitis, Inflammatory Bowel Diseases, Hepatitis, NASH - Nonalcoholic Steatohepatitis
- Trial name
- GREAT1 (NCT04306939)
- Testing
- venipuncture, Questionnaires, Additional Sample Collections
- Where
- United States
- Volunteers
- 120,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Pancreatic Cancer, IPMN, Pancreatic
Pancreatic Cancer Initial Detection Via Liquid Biopsy
The overall rationale of PANCAID is to provide a diagnostic blood test for early diagnosis of pancreatic cancer. With a set of different liquid biopsy methods, it is the aim to measure these markers in well-defined patient…
- Conditions
- Pancreatic Cancer, IPMN, Pancreatic, Individuals at Risk, Chronic Pancreatitis
- Trial name
- PANCAID (NCT06283576)
- Testing
- Liquid biopsy
- Where
- Sweden
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Pancreatic Neoplasms
Reinforced Staple Line on Leak Rate in Distal Pancreatectomy
The investigators propose a randomized, controlled trial of stapled pancreatic transection versus mesh reinforced stapled pancreatic transection.
- Trial name
- NCT01359410
- Testing
- Mesh reinforced staple line (SEAMGUARD), Stapled without mesh reinforcement (PER-STRIPS DRY)
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- Washington University School of Medicine
Intraductal Papillary Mucinous Neoplasm
Intra-operative Pancreatoscopy in Patients With IPMN
To demonstrate the added value of intraoperative pancreatoscopy in patients undergoing partial pancreatic resection for the treatment of Intraductal Papillary Mucinous Neoplasm (IPMN) as it pertains to detection of discontinuous…
- Trial name
- NCT03729453
- Testing
- SpyGlass
- Where
- 8 sites in United States, China and 4 more
- Volunteers
- 100 people
- Sponsor
- Boston Scientific Corporation
IPMN
Intraductal Papillary Mucinous Neoplasm With Malignant Change
Purpose: To investigate diagnostic performance of CT and MR in intraductal papillary mucinous neoplasm with malignant change according to international consensus guidelines 2012.
- Trial name
- NCT02044926
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Asan Medical Center
Benign Neoplasm of Liver and/or Biliary Ducts, Neoplasm of Uncertain Behavior of Biliary System
Endoscopic Evaluation of Premalignant Lesions in the Biliary Tract and Pancreatic Ducts
Single operater pancreatico-cholangioscopy is performed through the working channel of conventional duodenoscopes. A visual evaluation of the biliary and pancreatic ductal systems is completed and obvious or suspicious…
- Conditions
- Benign Neoplasm of Liver and/or Biliary Ducts, Neoplasm of Uncertain Behavior of Biliary System, Benign Neoplasms of the Pancreas, Neoplasms of the Pancreas
- Trial name
- NCT02057146
- Testing
- Duodenoscopy, pancreatoscopy, cholangioscopy, confocal microscopy
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Karolinska University Hospital
Whipple Operation
Dachengqi Decoction for Enhancing Early Gastrointestinal Recovery After Whipple Surgery
To investigate the clinical efficacy of the traditional Chinese medicine formula Dachengqi Decoction in promoting early gastrointestinal function recovery after Whipple surgery, and to evaluate its impact on postoperative…
- Trial name
- NCT06948474
- Testing
- Dachengqi decoction, modified gastrointestinal dual-lumen feeding tube, Normal Saline (0.9% NaCl)
- Where
- China
- Volunteers
- 45 people
- Sponsor
- China-Japan Friendship Hospital
Intraductal Papillary Mucinous Neoplasm of Pancreas, Pancreatic Neoplasms
Real-Time AI During Pancreatoscopy for Detection of Pancreatic Neoplasia
This prospective pilot study will evaluate the diagnostic performance of a previously validated artificial intelligence (AI) model when applied in real time during digital per-oral pancreatoscopy (POPS).
- Trial name
- NCT07809841
- Testing
- AIWorks-Cholangioscopy Real-Time Artificial Intelligence Model
- Where
- Ecuador
- Volunteers
- 60 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Pancreatic Cyst, Pancreas Cyst
Feasibility of Molecular Biology in Pancreatic Cyst Tumors
The main objective of the study is to compare the diagnostic accuracy of intra-cystic fluid DNA molecular analysis to standard diagnostics.
- Conditions
- Pancreatic Cyst, Pancreas Cyst, Serous Cystadenoma, Mucinous Cystadenoma
- Trial name
- CYST-GEN (NCT03305146)
- Testing
- Molecular biology analysis of pancreatic intra-cyst fluid
- Where
- 11 sites in France
- Volunteers
- 93 people
- Sponsor
- Hospital St. Joseph, Marseille, France
Fibrous Dysplasia of Bone
Hepato-pancreato-biliary Abnormalities in Fibrous Dysplasia of Bone/McCune Albright Syndrome
Fibrous dysplasia of bone /McCune Albright syndrome (FD/MAS) is a rare bone disease caused by somatic mutations in GNAS gene. This GNAS mutation predisposes to cancers, including breast cancer, thyroid cancer, chondrosarcoma and…
- Trial name
- TIM-DYS (NCT06177327)
- Testing
- Screening for hepato-bilio-pancreatic abnormalities in Fibrous dysplasia of bone /McCune Albright syndrome , description and characterization of the lesions.
- Where
- 16 sites in France
- Volunteers
- 545 people
- Sponsor
- Hospices Civils de Lyon
IPMN, Quality of Life
Quality of Life Assessment in Patients Who Are Under Surveillance for IPMN
Over 500 patients were participating in the IPMN follow up between september 2014 and august 2016 at the Helsinki University Hospital.
- Trial name
- NCT03131076
- Testing
- IPMN follow up
- Volunteers
- 300 people
- Sponsor
- Helsinki University Central Hospital
Pancreatic Ductal Adenocarcinoma (PDAC), Intraductal Papillary Mucinous Neoplasm of Pancreas
Predictive Biomarkers for Early Diagnosis of Pancreatic Ductal Adenocarcinoma (PDAC)
Pancreatic ductal adenocarcinoma (PDAC) is one of the cancers with the poorest prognosis and is often diagnosed at an advanced stage, resulting in very low 5-year survival rates.
- Conditions
- Pancreatic Ductal Adenocarcinoma (PDAC), Intraductal Papillary Mucinous Neoplasm of Pancreas, Pancreatic Intraepithelial Neoplasia
- Trial name
- B-PDAC (NCT07709052)
- Volunteers
- 180 people
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Intraductal Papillary Mucinous Neoplasm
Exploring Biomarkers of the Carcinogenesis of Intraductal Papillary Mucinous Neoplasm (IPMN) of the Pancreas
This is a prospective, open large cohort study to explore biomarkers for detecting early carcinogenesis of IPMN.
- Trial name
- NCT05433935
- Testing
- Observation
- Where
- China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Intraductal Papillary Mucinous Neoplasm of Pancreas, Pancreatic Cyst
Endocrine, Metabolic, Inflammatory Biomarkers to Identify Highgrade Dysplasia/invasive Carcinoma in Patients with IPMN of the Pancreas
Under the hypotheses that a more accurate patients selection could limit the problem of overtreatment and that benign intraductal papillary mucinous neoplasms (IPMN) have a distinguishable Endocrine/Metabolic/Inflammatory (EMI)…
- Trial name
- EMI-IPMN (NCT06706700)
- Where
- Italy
- Volunteers
- 586 people
- Sponsor
- IRCCS San Raffaele
Pancreatic Cancer
Stool Testing for Pancreatic Cancer
The purpose of this study is to determine if pancreatic cancer/pre-cancer can be detected in early stages through the molecular analysis of stool samples.
- Trial name
- NCT01104129
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Columbia University
Motor Function, Cognitive Function
Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years
This study is a postmarketing requirement jointly carried out by four NDA holders (Bayer AG, Bracco, GE Healthcare and Guerbet) and the CRO IQVIA.
- Conditions
- Motor Function, Cognitive Function, Contrast Media
- Trial name
- ODYSSEY (NCT04373564)
- Testing
- Motor Tests, Cognitive Tests, Unenhanced-MRI of the brain
- Where
- 51 sites in United States, Brazil and 6 more
- Volunteers
- 2,076 people
- Sponsor
- Guerbet
Pancreatic Cysts, Intraductal Papillary Mucinous Neoplasm
Early Detection of Pancreatic Cystic Neoplasms
This research is being done to learn more about pancreatic cysts. The tests that are currently available are imperfect at determining exactly what type of pancreatic cyst a person has, which cysts contain cancer, or what the risk…
- Conditions
- Pancreatic Cysts, Intraductal Papillary Mucinous Neoplasm, Pancreatic Mucinous-Cystic Neoplasm, Cystic, Mucinous and/or Serous Neoplasm
- Trial name
- NCT02110498
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- Johns Hopkins University
IPMN, Pancreatic, Pancreas Cancer
The LINFU® U.S. Registry in Patients With IPMN (Intraductal Papillary Mucinous Neoplasm of the Pancreas)
In this study, LINFU® will be evaluated in patients who have been identified with IPMN to determine if it can be used to help identify early, pancreatic ductal adenocarcinoma and its noninvasive precursor lesions (dysplasia).
- Conditions
- IPMN, Pancreatic, Pancreas Cancer, Pancreatic Cyst
- Trial name
- NCT06276764
- Testing
- LINFU®
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Adenocyte, LLC
Intraductal Papillary Mucinous Neoplasm
Intent of Surgery for IPMN
This multicenter retrospective observational cohort study seeks to: 1. Classify surgical intent in patients with resected Intraductal Papillary Mucinous Neoplasms (IPMN) and quantify the proportion of IPMN-associated cancers…
- Trial name
- NCT07216521
- Where
- 14 sites in United States, China and 3 more
- Volunteers
- 2,000 people
- Sponsor
- NYU Langone Health
Pancreas Cancer, Exosomes
ExoLuminate Study for Early Detection of Pancreatic Cancer
ExoLuminate is a nationally-enrolling registry study designed for earlier detection of cancer in patients at elevated risk or clinically-suspicious for pancreatic ductal adenocarcinoma (PDAC).
- Conditions
- Pancreas Cancer, Exosomes, Extracellular Vesicles, Pancreatic Neoplasms
- Trial name
- NCT05625529
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Biological Dynamics