Clinical trials: IUGR
Infant Malnutrition, Fetal Growth Retardation
DEUX OEUFs: Cracking the Potential of Eggs to Improve Child Growth and Development
This proposed randomized controlled trial aims to investigate the effect of maternal egg consumption during pregnancy on birth length.
- Trial name
- NCT06405360
- Testing
- Egg consumption
- Where
- Rwanda
- Volunteers
- 464 people, healthy volunteers welcome
- Sponsor
- University of Florida
Intrauterine Growth Restriction, Preeclampsia
Low Dose Aspirin for Preventing Intrauterine Growth Restriction and Preeclampsia in Sickle Cell Pregnancy (PIPSICKLE)
Pregnancy in sickle cell disease (SCD) is fraught with many complications including preeclampsia (PE) and intrauterine growth restriction (IUGR).
- Conditions
- Intrauterine Growth Restriction, Preeclampsia, Sickle Cell Disease, Pregnancy Complications
- Trial name
- PIPSICKLE (NCT05253781)
- Testing
- Low-dose aspirin
- Where
- 16 sites in Nigeria
- Volunteers
- 476 people, healthy volunteers welcome
- Sponsor
- University of Lagos, Nigeria
Preeclampsia
Randomizated Open-label Control Trial to Evaluate if the Incorporation of sFlt1/PlGF Ratio in the Diagnosis and Classification of PE Improves Maternal and Perinatal Outcomes in Women With the Suspicion of the Disease
Preeclampsia is a leading cause of maternal and neonatal morbidity and mortality worldwide. The morbidity and mortality of this condition arises from two main causes: 1) the lack of specific and sensible methods for its diagnosis…
- Trial name
- EuroPE (NCT03231657)
- Testing
- Placental biomarkers
- Where
- Spain
- Volunteers
- 2,536 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Fetal Growth Restriction
A Randomized Air Filter Intervention Study of Air Pollution and Fetal Growth in a Highly Polluted Community
The purpose of this study is to use an air filter intervention to evaluate the relationship between particulate matter air pollution exposure during pregnancy and fetal growth.
- Trial name
- NCT01741051
- Testing
- HEPA Filter
- Where
- Mongolia
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Simon Fraser University
Growth Failure, Adiposity
Optimal Growth of Preterm Infants With Growth Restriction
In this prospective randomized controlled multi center trial the investigators stratify "Very Low Birthweight " (VLBW)-infants with growth retardation in small for gestational age (SGA) or intrauterine growth restricted (IUGR) …
- Conditions
- Growth Failure, Adiposity, Diabetes, Neurologic Deficits
- Trial name
- OPTIGROW (NCT02999945)
- Testing
- SGA-enhanced nutrients, IUGR-enhanced nutrients, SGA-standard nutrients
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Preeclampsia and Intrauterine Growth Restriction
Placental Insufficiency Microcirculation Quantification by Ultrafast Doppler (MICRODOPPLER PLACENTA)
To identify fetuses small for their gestational-age who have reached their appropriate growth potential from growth-restricted fetuses due to placental insufficiency is uneasy.
- Trial name
- NCT03860103
- Where
- France
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Fetal Growth Retardation
OPtimal TIming of COrticosteroids in Early-onset Fetal Growth REstriction: the OPTICORE Study
The aim of this observational study is to optimize the timing of antenatal corticosteroids administered to patients with pregnancies complicated by early-onset fetal growth restriction in order to reduce neonatal morbidity and…
- Trial name
- OPTICORE (NCT05606497)
- Testing
- Corticosteroid
- Where
- Netherlands
- Volunteers
- 1,800 people
- Sponsor
- UMC Utrecht
Intrauterine Growth Restriction
Impact of Antioxidant Juice Intake on Brain Injury and Placental Pathology in Infants With Intrauterine Growth Restriction (IUGR)
Infants diagnosed with intrauterine growth restriction are at increased risk for brain injury in the neonatal period, and eventually increased risk for adverse long-term neurodevelopmental outcomes.
- Trial name
- NCT04394910
- Testing
- Pomegranate Juice
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Brigham and Women's Hospital
Fetal Growth Retardation
Prediction of Placental Fetal Growth Restriction in High Risk Population (PoPFGR)
This study intends to prospectively enroll high-risk pregnant women to establish a multicenter cohort. By combining maternal basic characteristics, medical history, early pregnancy ultrasound, and biological markers, we aim to…
- Trial name
- NCT06096805
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Fetal Growth Restriction
Sildenafil Citrate for Treatment of Growth-restricted Fetuses
The aim of this study is to assess the effect of Sildenafil citrate therapy on neonatal outcomes in women with fetal growth restriction.
- Trial name
- NCT03177824
- Testing
- Sildenafil Citrate 25Mg Tab
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Obesity, Small for Gestational Age
Maternal Obesity and Small for Gestational Age Infants
The purpose of this retrospective pilot study is to address the effect that obesity, in the absence of other comorbidities, has on birth weight.
- Trial name
- NCT00371657
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University Center for Health Sciences
Romberg's Disease, Craniofacial Microsomia
Role of Mesenchymal Stem Cells in Fat Grafting
Contour deformity of face causes both functional as well as aesthetic problems for the patient. Fat being an autologous tissue source is considered as an ideal soft-tissue filler because it is abundant, readily available…
- Conditions
- Romberg's Disease, Craniofacial Microsomia, Lipodystrophy, Mixed Connective Tissue Disease
- Trial name
- NCT02494752
- Testing
- Fat graft enriched with ex vivo expanded stem cells, Fat graft not enriched with ex vivo expanded stem cells
- Volunteers
- 30 people
- Sponsor
- King Edward Medical University
Down Syndrome,Auxological Indexes, Auxological Parametars, Intrauterine Growth Restriction
Indicators of Growth, Nutritional Status and Comorbide Disorders of Newborns With Down Syndrome
Objective To access predictive values of the auxological parameters and indexes for risk of comorbid malformations in newborns with Down syndrome (DS) Study design In this cohort retrospective study, 141 newborns with proven…
- Trial name
- DownSy (NCT03553706)
- Where
- Croatia
- Volunteers
- 141 people
- Sponsor
- University Hospital of Split
Fetal Growth Restriction (FGR)
AI-Based Ultrasound Prediction of Pregnancy Outcomes in Placental-Related Fetal Growth Restriction (MVM-FGR): A Prospective Cohort Study
The goal of this prospective cohort study is to enroll pregnancies complicated by placental-related fetal growth restriction (FGR) and to develop predictive models for adverse short- and long-term outcomes.
- Trial name
- NCT07473739
- Testing
- new ultrasound index and MRI
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Arterial Stiffness, Fetal Growth Retardation
Bioimpedence and Arterial Function Monitoring at Birth and in Infants
Babies may be born appropriately grown for gestational age (AGA, >10th centile) or small for gestational age (SGA, <10th centile).
- Conditions
- Arterial Stiffness, Fetal Growth Retardation, Small for Gestational Age at Delivery, Pre-Eclampsia
- Trial name
- BAMBI (NCT04720690)
- Testing
- Vicorder: pulse wave velocity, pulse wave analysis, stroke volume, cardiac output, NICaS, Echocardiography and ultrasound of arteries
- Where
- 2 sites in United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Infant, Very Low Birth Weight
Urine VEGF Levels in Very Low Birth Weight (VLBW) Infants
VLBW infants are at risk of developing retinopathy of prematurity (ROP). In the first phase of ROP there is a down-regulation of retinal VEGF-expression because of postnatal relative hyperoxia, followed by an upregulation of VEGF…
- Trial name
- NCT00799721
- Where
- Germany
- Volunteers
- 160 people
- Sponsor
- Charite University, Berlin, Germany
Cervix; Pregnancy, Inherited Genetic Conditions (Diagnosis)
Optimization of Cervical Collections in Pregnancy
Fetal cells are not easily obtained from pregnant patients; this curtails testing to assess the health of the fetus and the mother.
- Conditions
- Cervix; Pregnancy, Inherited Genetic Conditions (Diagnosis), Preeclampsia, Fetal Growth Retardation
- Trial name
- OCCP (NCT06323187)
- Testing
- Cervical Sampling
- Volunteers
- 2,600 people, healthy volunteers welcome
- Sponsor
- Dr. Sascha Drewlo
Pregnancy Complications, Maternal Death
Nutrition Optimalization Among Pregnant Women to Improve Maternal and Neonatal Outcome in DKI Jakarta
The goal of this MONAS Study is to learn about comprehensive monitoring and nutritional intervention among pregnant women in order to improve maternal and neonatal outcomes. The main questions it aims to answer are: 1.
- Conditions
- Pregnancy Complications, Maternal Death, Preeclampsia, Intrauterine Infection
- Trial name
- MONAS (NCT06268509)
- Testing
- Nutritional panel laboratory examination, Pregnancy supplements (other than provided by Ministry of Health), Fetomaternal ultrasound
- Where
- Indonesia
- Volunteers
- 245 people
- Sponsor
- Dr Cipto Mangunkusumo General Hospital
Fetal Growth Restriction (FGR)
DIFFUSION WEIGHTED MRI FINDINGS IN FETUSES WITH AND WITHOUT FETAL GROWTH RESTRICTION
This prospective observational study aims to compare fetal brain diffusion-weighted magnetic resonance imaging (DWI) findings in fetuses with and without fetal growth restriction (FGR) and to evaluate the association between…
- Trial name
- NCT07769957
- Testing
- Diffusion-weighted fetal brain MRI
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul Training and Research Hospital
Pre-Eclampsia
Interest of Circulating Endothelial Biomarkers in Vascular Pregnancy Complications
This is a prospective multicentric study including four clinical units of Gynecology and Obstetrics (3 public health hospitals and one private team), one research team in Hematology and one Center of Clinical investigation (CIC).
- Trial name
- NCT00485784
- Testing
- Blood test
- Where
- 4 sites in France
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille