Clinical trials: IVF, open to volunteers
IVF, Window of Implantation
Trial to Evaluate the Clinical Utility of Non-invasive Endometrial Receptivity Test (Ora) in Patients With Implantation Failure
The adjustment of the timing of embryo transfer based on the endometrial receptivity profile and transferring embryo(s) of good quality with normal chromosomes (diagnosed by Preimplantation Genetic Testing for Aneuploidy, PGT-A)…
- Conditions
- IVF, Window of Implantation, microRNA, Implantation
- Trial name
- NCT06544837
- Testing
- Window of Implantation
- Where
- Vietnam
- Volunteers
- 1,000 people
- Sponsor
- Inti Labs
Assisted Reproductive Technology, Female Infertility
A Comparing Study Between SJ04 and Ovidrel® in Healthy Subjects
This is a single-centre, randomised, open-label, single-dose, two-cycle, double-crossover study to compare the pharmacokinetics of SJ04 and Ovidrel® in healthy female subjects.
- Trial name
- NCT06599528
- Testing
- T-R (Test-Reference drug), R-T (Reference-Test drug)
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Suzhou Centergene Pharmaceuticals Co.,Ltd.
Infertility, In Vitro Maturation of Oocytes
Aspire In Vitro Maturation Study
A study to assess the Capacitation - in-vitro maturation (CAPA-IVM) system as an option for patients with a good ovarian reserve to achieve pregnancy.
- Conditions
- Infertility, In Vitro Maturation of Oocytes, Assisted Reproduction Technologies
- Trial name
- AIM (NCT07789730)
- Testing
- CAPA-IVM
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Inception Fertility Research Institute, LLC
Infertility (IVF Patients)
Pilot Study of Discarded Blastocysts
The goal of this observational study is to determine multiomics patterns related to global embryo quality to help overcome the limitations of conventional embryo quality assessment.
- Trial name
- DECODE (NCT07429097)
- Testing
- Multiomics analysis
- Where
- Norway
- Volunteers
- 150 people
- Sponsor
- Igenomix
Infertility (IVF Patients)
Study of Abnormally Fertilized Embryos
The goal of this observational study is to determine the diploidy rate of haploid and triploid embryos from in vitro fertilization (IVF) cycles.
- Trial name
- SAFE (NCT06940973)
- Testing
- Parental samples, PGT-A, TE rebiopsies and spent blastocyst media collection
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Igenomix
Infertility, Female, Infertility, Male
Embryo Assessment Utilizing Timelapse Imaging in Conjunction With Preimplantation Genetic Testing for Aneuploidy With Next Generation Sequencing
The goal of this observational study is to discern if there is a relationship between timelapse imagery of human oocytes/embryos and PGT results.
- Conditions
- Infertility, Female, Infertility, Male, Infertility, IVF
- Trial name
- NCT06419127
- Testing
- Timelapse incubation and PGT
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Gattaca Genomics
IVF, Controlled Ovarian Simulation
Menopur And Rekovelle Combination Study Version 2.0
The goal of this clinical trial is to evaluate the safety and effectiveness of a personalized ovarian stimulation regimen in women aged 18 to 40 undergoing in vitro fertilization (IVF).
- Conditions
- IVF, Controlled Ovarian Simulation, Fertility Disorders
- Trial name
- MARCS 2 (NCT06997900)
- Testing
- Combination therapy : Follitropin delta and HP-hMG
- Where
- 2 sites in Canada
- Volunteers
- 200 people
- Sponsor
- Clinique Ovo
Infertility (IVF Patients)
An Advanced Decision Support Tool for Personalized Medicine for IVF Using Modeling and Optimization for Provera
A clinical trial will determine the effectiveness of using the Opt-IVF decision support tool for each patient's personalized and optimal drug dosage profile in the United States.
- Trial name
- NCT07148999
- Testing
- Opt-IVF, Control
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Urmila DIwekar
IVF Outcomes
Ovarian Stimulation Outcomes During a GnRH Antagonist Protocol for In-vitro Fertilization When Comparing Trigger Day Decision by Physicians Versus an Artificial Intelligence-based Algorithm.
To compare the number of mature oocytes following a GnRH antagonist in-vitro fertilization stimulation cycle when comparing trigger day timing decision by physicians versus an artificial intelligence-based algorithm
- Trial name
- NCT07110285
- Testing
- Artificial intelligence-based algorithm
- Where
- Israel
- Volunteers
- 180 people
- Sponsor
- FertilAI
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
IVF\ICSI Outcome in Women With Polycystic Ovary Syndrome
Polycystic ovarian syndrome (PCOS) occurs in 5% to 10% of all women of reproductive age and 50% of women who present with sub-fertility due to anovulatory infertility .
- Trial name
- NCT05756023
- Testing
- the pregnancy rate at IVF / ICSI cycles
- Where
- Egypt
- Volunteers
- 156 people
- Sponsor
- Egymedicalpedia
Infertility
International Pilot Study for Dual Non-invasive Assesment of Embryo Development
Choosing the best embryo is one of the major challenges for achieving success in in vitro fertilization (IVF). Traditionally, embryo evaluation has been based on morphological quality (how the embryo looks like) and chromosomal…
- Trial name
- PANDORA (NCT06524648)
- Testing
- niPGT-A
- Where
- 8 sites in Austria, Spain and 1 more
- Volunteers
- 200 people
- Sponsor
- Igenomix
Repeated IVF Failure, Female Infertility
Investigate the Efficacy of Using NMN to Improve Embryo Development Capacity.
The objective of this study is to investigate the efficacy of NMN supplementation in enhancing embryo developmental capacity and improving IVF success rates in patients experiencing IVF failures.
- Trial name
- NCT06629636
- Testing
- NMN capsule
- Where
- Japan
- Volunteers
- 60 people
- Sponsor
- Sunkaky Medical Cooperation
Polygenic Score
Polygenic Embryo Selection
This study will evaluate whether IVF success rates after PRS-based embryo selection differ from those after morphology-based embryo selection, and whether polygenic disease risk correlates with embryo morphology.
- Trial name
- NCT07841769
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Nucleus Genomics Inc.
Infertility (IVF Patients)
The Role of hCG in Thawed Embryo Transfer
This prospective randomized trial will assess the relevance, if any, of a corpus luteum induced by hCG in transfers of thawed embryos.
- Trial name
- NCT07004192
- Testing
- HCG injection, No intervention
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Fertility Center of Las Vegas
Infertility Assisted Reproductive Technology, Infertility (IVF Patients)
Blastocyst AI Assisted Morphokinetics in ART
The goal of this observational study is to learn if embryo characteristics obtained via the recording of real-time embryo activity via 30-seconds video capture (e.g.: Embryo Morphokinetics) can correlate with known embryo outcome…
- Trial name
- AIM (NCT07611448)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Viable Biosciences
Idiopathic Infertility, Infertility Unexplained
Biological Aging Hallmarks-Guided Integrative TCM and Conventional Medicine in Post-Treatment Unexplained Female Infertility
The goal of this clinical trial is to determine whether telomere profiling and other biological aging hallmarks can help identify underlying mechanisms of persistent infertility in women with post-treatment unexplained…
- Conditions
- Idiopathic Infertility, Infertility Unexplained, Infertility (IVF Patients), Infertility Assisted Reproductive Technology
- Trial name
- TECMI (NCT07404969)
- Testing
- 1. Aging Hallmarks Biomarker Profiling (Telomere-Based), 2. Integrative Botanical and Nutraceutical Intervention, 3. Natural Conception or Assisted Reproductive Technologies
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- BEYOND GENOMiX SA, AG, Ltd
In Vitro Maturation of Oocytes
Fertilo In Vitro Research Study and Trial
The goal of this clinical trial is to evaluate the safety and efficacy of using Fertilo for In vitro maturation (IVM) in participants 18-35 years of age.
- Trial name
- FIRST (NCT06858111)
- Testing
- Fertilo, Medicult IVM
- Where
- 16 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Gameto, Inc.
Infertility
Safety and Efficacy of Corifollitropin Alfa N02 Injection in Elderly Women Undergoing Assisted Reproductive Technology (ART)
This is a multi-centre, single-arm, observational trial to assess the safety and efficacy of corifollitropin alfa N02 Injection in elderly Chinese women undergoing ART, and then to explore the compliance and satisfaction during…
- Trial name
- NCT07553728
- Testing
- NA，Observational study
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Infertility, Mosaicism
Non-Euploid Embryo Transfer (NEET) Registry
The NEET Registry is a registry to track and study the outcomes of non-euploid embryo transfers (NEET) in The Prelude Network
- Conditions
- Infertility, Mosaicism, Aneuploidy
- Trial name
- NCT07036536
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Inception Fertility Research Institute, LLC
Infertility
Hormone-free Antral Retrieval for Viable Embryo Storage & Transfer
This study is testing whether eggs can be collected from small follicles without using the usual ovarian stimulation medications. Participants will have up to three egg retrieval procedures.
- Trial name
- HARVEST (NCT07801105)
- Testing
- CAPA-IVM System, Serial Unstimulated Transvaginal Oocyte Retrieval, ICSI, Blastocyst Culture, PGT-A, Embryo Vitrification/Accumulation, and Single Euploid Embryo Transfer
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Kevin Doody