Clinical trials: IVf
Infertility
Evaluation of Patient Experience and Quality of Life During In Vitro Fertilization Treatment
This study will evaluate if an electronic medication management software solution can improve outcomes for patients undergoing in vitro fertilization (IVF) treatment.
- Trial name
- NCT03383848
- Testing
- Medication Management Software
- Where
- 2 sites in United States
- Volunteers
- 164 people
- Sponsor
- University of Michigan
Embryo
Effect of Degranulation Needle With Different Diameters on the Rate Good Embryo in IVF
Good-quality embryos are critical for the success of in vitro fertilization (IVF). But, to date, there is no report of the effect of different diameters denuding pipette on the embryos quality.
- Trial name
- NCT03810040
- Testing
- 140 microns denuding pipette, 150 microns denuding pipette
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Infertility, Female
Pregnancy Success Rates of Acupuncture for in Vitro Fertilization
This study evaluates the effectiveness of acupuncture on pregnancy success before embryo transfer in IVF treatment in female infertile patients.
- Trial name
- Acupuncture (NCT03572608)
- Testing
- Acupuncture treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ataturk University
Infertility
Mild Versus Conventional Ovarian Stimulation for Poor Responders Undergoing In Vitro Fertilisation
The investigators will examine the balance between IVF success in terms of outcome parameters, using a mild ovarian stimulation protocol, opposing it to the conventional stimulation regimens in poor responders undergoing IVF.
- Trial name
- NCT01319708
- Testing
- mild ovarian stimulation, conventional ovarian stimulation
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- National and Kapodistrian University of Athens
Female Infertility, Obesity
Effect of the Glycemic Index of Diet on Metabolic and Reproductive Parameters in Overweight and Obese Infertile Women
Infertility has been currently recognized as a disorder related to obesity. Among several metabolic changes associated with obesity, insulin resistance appears to be linked to hormonal disorders that affect reproductive system.
- Trial name
- NCT02416960
- Testing
- Low Glycemic Index Diet Group, Conventional Diet Group
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Infertility
Physiotherapy in Assisted Reproductive Treatment
Research examines the effect of physiotherapy on treatment success by assisted reproductive technologies. It is based on a treatment of infertility by physiotherapeutic intervention after which the participants will undergo a…
- Trial name
- NCT04971824
- Testing
- Physiotherapeutic intervention
- Where
- Czechia
- Volunteers
- 42 people
- Sponsor
- Klaudia Fabičovic, PT
Infertility
Impact of Follicular and Blood G-CSF During a Natural Cycle of IVF
Recently, scientists look into G-CSF (Granulocyte - Colony Stimulatin Factor). The use of this molecule is increasing in reproduction pathology.
- Trial name
- GCSFnat (NCT01668225)
- Testing
- Blood test
- Where
- Canada
- Volunteers
- 152 people
- Sponsor
- Clinique Ovo
IVF
Efficacy of Micronized Natural Progesterone vs GnRH Antagonist in the Prevention of LH Peak During Ovarian Stimulation.
This study aims to investigate if the use of oral micronized natural progesterone is not inferior to the use of subcutaneous antagonist in preventing LH peak in controlled ovarian stimulation.
- Trial name
- PRO_NAT (NCT05954962)
- Testing
- Progesterone 200 MG, Ganirelix Acetate
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Instituto Bernabeu
Infertility
Dydrogesterone Versus GnRH Antagonist in Poor Responders Undergoing Double Ovarian Stimulation
The aim of this randomized controlled trial is to compare the efficacy and cost-effectiveness of using progestin with GnRH antagonist to prevent premature LH surge in poor responders undergoing double stimulation protocol.
- Trial name
- NCT06212102
- Testing
- Progestin primed ovarian stimulation, GnRH antagonist
- Where
- 2 sites in Egypt
- Volunteers
- 120 people
- Sponsor
- Bedaya Hospital
in Vitro Fertilization, Hormone Testing
Superovulation And Urinary Concentration of Estrone
To determine if measurement of urinary estrone glucuronide concentrations with an at-home device is correlated with superovulatory response during gonadotropin stimulated IVF cycles.
- Trial name
- SAUCE (NCT05493202)
- Testing
- Mira Fertility Tracker
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Olive Fertility Centre
Infertility
Diafert for Embryo Selection and Fertility Improvement
Prospective, single-center, single-blind, randomized, controlled, two-arm, interventional study.
- Trial name
- DESTINy (NCT02586272)
- Testing
- Daifert, Control Group
- Where
- Belgium
- Volunteers
- 61 people
- Sponsor
- Forest Laboratories
Hormone Disturbance
Oocyte Retrieval Progesterone Levels and IVF
Objective: To assess whether basal hormonal level can predict the elevation of P4 on the day of oocyte retrieval, as well as to examine the impact of P4 elevation on the day of oocyte retrieval on the outcome of assisted…
- Trial name
- NCT04447677
- Volunteers
- 164 people
- Sponsor
- University of Belgrade
Female Infertility Due to Diminished Ovarian Reserve
Alpha-Lipoic Acid Supplementation and IVF Outcomes in Women of Advanced Maternal Age
Female fertility declines with advancing age, largely because of deteriorating oocyte quality driven by mitochondrial dysfunction and oxidative stress within the ovarian microenvironment.
- Trial name
- NCT07685431
- Testing
- Alpha-Lipoic Acid (ALA)
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Fertility Agents, Female
hCG Supplementation in Frozen-Thawed Embryo Transfer Cycle
The implantation rate after frozen-thawed embryo transfer cycles depends mostly on the receptivity of the endometrium and the embryo quality.The effects of human chorionic gonadotropins (hCG) on the endometrium have been…
- Trial name
- NCT00398229
- Testing
- s.c. human chorionic gonadotropin (Ovitrelle)
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Hadassah Medical Organization
Infertility
GnRH for Luteal Support in IVF/ICSI/FET Cycles
During IVF cycles an embryo is generally placed into the uterine cavity between 3 and 5 days after fertilization. For a successful pregnancy to take place, that embryo must then implant in the properly primed and staged…
- Trial name
- NCT02357654
- Testing
- GnRH
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- University Reproductive Associates
In Vitro Maturation of Oocytes
Fertilo In Vitro Research Study and Trial
The goal of this clinical trial is to evaluate the safety and efficacy of using Fertilo for In vitro maturation (IVM) in participants 18-35 years of age.
- Trial name
- FIRST (NCT06858111)
- Testing
- Fertilo, Medicult IVM
- Where
- 16 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Gameto, Inc.
Infertility, Female
Laparoscopy in Failed IVF
Current in-vitro fertilization (IVF) consumers are enjoying better success rates than early seekers, but only about a quarter of IVF cycles result in a live birth and many patients remain infertile after multiple IVF attempts.
- Trial name
- NCT06165484
- Testing
- laparoscopy and hysteroscopy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Reproductive Performance Following Ovarian Transplantation
Transplantation of Frozen Thawed Ovarian Tissue High Reproductive Performance
Design: prospective cohort study. Setting: Tertiary university-affiliated ART and oncology centers. Patients: 20 cancer survivors who underwent ovarian transplantation of frozen-thawed ovarian tissue, with the aim to conceive.
- Trial name
- NCT02659592
- Testing
- transplantation of ovarian tissue
- Volunteers
- 20 people
- Sponsor
- Sheba Medical Center
Polycystic Ovary Syndrome (PCOS), Female Infertility
Comparison of IVF Outcomes Between PPOS and Antagonist Protocols in Women With PCOS
This study aims to compare the outcomes of two ovarian stimulation protocols used in in vitro fertilization (IVF): the progestin-primed ovarian stimulation (PPOS) protocol and the GnRH antagonist protocol.
- Trial name
- PPOS-PCOS-IVF (NCT07394530)
- Testing
- Progestin-Primed Ovarian Stimulation (PPOS), GnRH Antagonist Protocol
- Where
- Vietnam
- Volunteers
- 400 people
- Sponsor
- Hanoi General Hospital (Vietnam)
IVF
Opt-IVF Multi-center Trial 2 Including All Protocols
A multi-center randomized clinical trial is proposed to study the effectiveness of the advanced decision support tool Opt-IVF for ALL PROTOCOLS in reducing medication, testing, and improving outcomes.
- Trial name
- NCT05981898
- Testing
- OPTIVF dosage, traditional Dosage
- Where
- India
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Stochastic Research Technologies LLC