Clinical trials: Iatrogenic Effect
Intervention (Training) Condition
The Effect of Cognitive Behavioral Therapy
The aim of this study is to investigate the effect of hand hygiene training applied using cognitive behavioural therapy techniques on healthcare workers' attitudes and beliefs regarding nosocomial infections.
- Trial name
- AHIEVRAN (NCT07506915)
- Testing
- Hand hygiene training using cognitive behavioural therapy techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Ventilator Associated Pneumonia ( VAP)
Effect of Two Oral Care Methods on Oral Flora and VAP in Mechanically Ventilated Patients
This randomized controlled trial aims to evaluate the effect of two oral care methods on oral bacterial colonization and ventilator-associated pneumonia (VAP) in mechanically ventilated intensive care unit (ICU) patients.
- Trial name
- ORAVAP-RCT (NCT07283380)
- Testing
- Pediatric toothbrush, Sponge stick
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Marmara University
Hospital Acquired Infection
Effect of Copper Impregnated Textiles on Healthcare Associated Infections and Antibiotic Use
This is a prospective Infection Control study comparing rates of antibiotic usage and infections in the General Intensive Care Unit (GICU) in beds with copper impregnated linens versus regular linens.
- Trial name
- NCT02351895
- Testing
- Copper impregnated linen
- Where
- United States
- Volunteers
- 1,302 people
- Sponsor
- Eastern Virginia Medical School
Ventilator Associated Pneumonia
Effect of a Constructivist Educational Program on Preventing Ventilator-Associated Pneumonia in Intensive Care Units
This study is designed to investigate the impact of a constructivist education program on nurses and cleaning personnel regarding the preventive care bundle for the prevention of ventilator-associated pneumonia in the intensive…
- Trial name
- NCT07102407
- Testing
- Contructivist, Routine training
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Karaman Training and Research Hospital
Hypoglycemia; Iatrogenic
Liver Glycogen and Hypoglycemia in Humans
The purpose of this research study is to learn more about how sugar levels in the liver affect the ability of people both with and without type 1 diabetes.
- Trial name
- NCT03241706
- Testing
- Low Fructose, Saline, Somatostatin
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jason Winnick
Pneumonia, Viral, Ventilator Associated Pneumonia
Acyclovir in Ventilated Patients With Pneumonia and HSV-1 in BAL
Almost 90 out of 100 people carry herpes simplex viruses (HSV). Once a person has been infected with the herpes viruses, he or she can't get rid of them for the rest of her/his life.
- Conditions
- Pneumonia, Viral, Ventilator Associated Pneumonia, Community-acquired Pneumonia, Herpes Simplex
- Trial name
- HerpMV (NCT06134492)
- Testing
- Acyclovir
- Where
- 28 sites in Germany
- Volunteers
- 616 people
- Sponsor
- Jena University Hospital
Ventilator Associated Pneumonia, Tracheobronchitis
Effect of Chlorhexidine-Induced Oral Care on Ventilator-Related Some Respiratory System Complications
Ventilator-associated pneumonia and ventilator-associated treakeabronchitis in respiratory tract infections associated with ventilator are common infections in intensive care unit and cause significant morbidity, mortality and…
- Trial name
- NCT04505202
- Testing
- 0.12% chlorhexidine gluconate
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Iatrogenic Effect
Effect of the Use of a Therapeutic Conciliation Document at the Outlet of Hospital, on the Emergency Use of Hospital Care in Patient Aged Over 75 Years Old.
The drug iatrogenesis represents an important public health problem. In the Iatromed project, we want to to assess a specific therapeutic drug conciliation sheet (TDC).
- Trial name
- IATROMED (NCT02916836)
- Testing
- therapeutic drug conciliation sheet (TDC), No Use of therapeutic drug conciliation sheet (TDC)
- Sponsor
- Centre Hospitalier Universitaire de Nice
Mechanical Ventilation Complication, Ventilator Associated Pneumonia
Effects of Endotracheal Tube Cuff Pressure Control on Microaspiration of Gastric Contents
The purpose of study is to determine effects of three different ET cuff pressure control on microaspiration of the stomach contents.
- Conditions
- Mechanical Ventilation Complication, Ventilator Associated Pneumonia, Nursing Caries, Aspiration, Respiratory
- Trial name
- NCT04061083
- Testing
- Smart Cuff Manager, Manometer
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Afyonkarahisar Health Sciences University
Intensive Care Unit, Health Care Associated Infection
The Effect of Care-oriented Practical Training on Nurses' Intensive and Critical Care Competency and HAIs Indicators
It was aimed to evaluate the effect of care-oriented practical training on the intensive and critical care competencies of nurses, the hand hygiene compliance rate of nurses and care support staff, and HAI indicators.
- Conditions
- Intensive Care Unit, Health Care Associated Infection, Patient-Centered Care, Competence
- Trial name
- NCT06239987
- Testing
- Care-oriented Practical Training
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people
- Sponsor
- Akdeniz University
Coagulopathy, Nosocomial Pneumonia
Effect of Antioxidant Vitamins on Coagulopathy and Nosocomial Pneumonia After Severe Trauma
The purpose of this study is to determine the effect of antioxidant vitamins (vitamins C and E) on the development of coagulation derangements and nosocomial pneumonia after severe trauma in patients.
- Trial name
- NCT01897792
- Testing
- Vitamin C, Vitamin E, Saline (for Vitamin C)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Alabama at Birmingham
Infections, Nosocomial, Infections, Respiratory Tract
Antibacterial Effect of Zinc Oxide Nanoparticles on Acinetobacter Baumannii Isolated From Patients With Hospital Acquired Infections in Sohag University Hospitals, Egypt
A. baumannii is known as the most frequently isolated organism in intensive care units (ICUs), causing a variety of nosocomial infections, including pneumonia, urinary tract infections (UTIs), bacteremia as well as skin and soft…
- Trial name
- NCT06628076
- Testing
- Culture specific antibiotic therapy, Antibiotic, Biofilm assessment
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Sohag University
Ventilator Associated Pneumonia
Effect of Educational Program About Preventive Care Bundle for Prevention of Ventilator Associated Pneumonia Among Newborns
This study is designed to investigate the effect of educational program for nurses about preventive care bundle for prevention of ventilator associated pneumonia among newborns.
- Trial name
- NCT06066489
- Testing
- educational program about VAP
- Volunteers
- 137 people
- Sponsor
- Damanhour University
Nutrition Disorders
Comparison of Continuous Versus Intermittent Enteral Nutrition in Critically Ill Patients.
The purpose of the study is to compare continuous versus intermittent strategy for enteral nutrition. The study will examine if there is a difference in achieving nutritional delivery goals, tolerance and number of complications…
- Trial name
- COINN (NCT03573453)
- Testing
- enteral nutrition
- Where
- Czechia
- Volunteers
- 300 people
- Sponsor
- Masaryk University
Nosocomial Pneumonia (NP), Ventilator-associated Pneumonia (VAP)
A Study Comparing Ceftazidime-Avibactam Versus Meropenem in Hospitalized Adults With Nosocomial Pneumonia
The purpose of the study is to evaluate the effects of Ceftazidime-Avibactam compared to Meropenem for treating hospitalized adults with nosocomial pneumonia including ventilator-associated pneumonia
- Trial name
- NCT01808092
- Testing
- ceftazidim-avibactam (CAZ-AVI, experimental product), meropenem (active comparator)
- Where
- 123 sites in Argentina, Brazil and 24 more
- Volunteers
- 969 people
- Sponsor
- Pfizer
Ventilator-associated Pneumonia and Oral Health
The Effect of Two Different Oral Care Solutions on Ventilator-Associated Pneumonia and Oral Health of Mechanically Ventilated Patients in the Intensive Care Unit
The aim of this observational study is to evaluate the effects of two different oral care solutions on ventilator-associated pneumonia and oral health in mechanically ventilated participants in the intensive care unit.
- Trial name
- NCT06966817
- Testing
- control group(chlorhexidine), Experimental Group(cetylpyridinium chloride)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Saglik Bilimleri Universitesi
Pneumonia
Probiotic Enteral Administration in Mechanically Ventilated Patients
The objective of this study is to assess the effects of a daily enteral supplementation with probiotics within a population of critically ill, mechanically ventilated patients.
- Trial name
- NCT00122408
- Testing
- Ergyphilus
- Where
- 3 sites in France
- Volunteers
- 740 people
- Sponsor
- Central Hospital, Nancy, France
Carbapenemase-Producing Enterobacteriaceae (CPE), Healthcare-Associated Infections (HAIs)
Effect of Daily Chlorhexidine Bathing and Antibiotic/PPI Stewardship on Prevention of CPE Transmission and Infection
This multicenter, cluster-randomized crossover trial aims to evaluate the effectiveness and safety of a bundled intervention-including daily chlorhexidine bathing and targeted antimicrobial and proton pump inhibitor (PPI)…
- Trial name
- NCT07039955
- Testing
- Daily Chlorhexidine Bathing, Antimicrobial and PPI Stewardship Program, Standard Bathing
- Where
- 3 sites in South Korea
- Volunteers
- 5,760 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Iatrogenic Disease
Incidence of Iatrogenic Diseases on Hospital's Emergency Consultations
French population grows older year after year: 24.3% people were over 60 years old in 2006 against 20.6% in 2000 and the expected number might be over 33% in 2050.
- Trial name
- EIU (NCT03960398)
- Testing
- Iatrogenic disease impact on emergency consultations
- Where
- 2 sites in France
- Volunteers
- 2,500 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Healthcare Associated Infection, Nosocomial Infection
Red Light Photobiomodulation and Topical Disinfectants
The goal of this clinical trial is to evaluate the potential effects of photobiomodulation when used with topical disinfectants in the anterior nares of healthy adults.
- Conditions
- Healthcare Associated Infection, Nosocomial Infection, Surgical Site Infection
- Trial name
- NCT05797818
- Testing
- Methylene Blue Only, Chlorhexidine Gluconate Only, Methylene Blue + Chlorhexidine Gluconate
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ondine Biomedical Inc.