Clinical trials: Ibuprofen
Musculoskeletal Pain, Acute Pain
Efficacy and Safety Study of Ibuprofen Gel Compared to Placebo in the Treatment of Acute Musculoskeletal Pain
Phase III clinical trial, multicentre of superiority, randomized, double-blind, parallel groups, placebo-controlled and use of ibuprofen gel in the treatment of acute pain.
- Conditions
- Musculoskeletal Pain, Acute Pain, Stretch, Sprains
- Trial name
- PROGEL (NCT05013567)
- Testing
- Ibuprofen gel
- Volunteers
- 300 people
- Sponsor
- Brainfarma Industria Química e Farmacêutica S/A
Dental Pain
Maxigesic 325 Acute Dental Pain Study
The purpose of this study is to determine whether the analgesic effects of Maxigesic USA are greater than acetaminophen, ibuprofen or placebo.
- Trial name
- NCT01420653
- Testing
- Maxigesic 325, Acetaminophen, Ibuprofen
- Where
- 4 sites in United States, New Zealand
- Volunteers
- 408 people
- Sponsor
- AFT Pharmaceuticals, Ltd.
Leg Ulcers
Biatain Ibu vs. Biatain in Painful Chronic Venous Leg Ulcers
The objective of this investigation is to demonstrate the effectiveness and safety of Biatain Ibu non-adhesive foam dressing compared to Biatain non-adhesive foam dressing.
- Trial name
- NCT00627094
- Testing
- Biatain, Biatain Ibu
- Where
- 13 sites in Denmark, France and 2 more
- Volunteers
- 120 people
- Sponsor
- Coloplast A/S
Chronic Pain
To Evaluate the Food Effect and the Absorption Profile of Ibuprofen Modified-Release Tablets 800 mg
An open-label, randomized, 3-way crossover study to evaluate the pharmacokinetics of investigational product "Ibuprofen Modified-Release Tablets 800 mg" in comparison to the reference standard "Ibuprofen Regular-Release Tablets…
- Trial name
- NCT05329454
- Testing
- Ibuprofen Tablets
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Overseas Pharmaceuticals, Ltd.
Pain, Postoperative, Tooth Diseases
Efficacy and Safety of Ibuprofen and Caffeine in Dental Pain
The primary objective of this study is to compare the efficacy of a combination product containing ibuprofen 400 mg and caffeine 100 mg versus either ingredient alone as well as placebo for the treatment of post-surgical dental…
- Trial name
- NCT01929031
- Testing
- ibuprofen + caffeine, ibuprofen, caffeine
- Where
- United States
- Volunteers
- 562 people
- Sponsor
- Boehringer Ingelheim
Cancer, Overall Survival
Study of the Safety, Tolerability and Efficacy of Metabolic Combination Treatments on Cancer
The purpose of this study is to determine the effectiveness of a regimen of selected metabolic treatments for patients with cancer in a real world setting and to conduct exploratory analysis on the relationship between the degree…
- Trial name
- METRICS (NCT02201381)
- Testing
- Metabolic treatment
- Where
- United Kingdom
- Sponsor
- Health Clinics Limited
Back Pain, Neck Pain
Ibuprofen/Caffeine Lower Back or Neck Pain Study
To assess the efficacy and safety of a 400 mg ibuprofen/100 mg caffeine tablet in comparison to a 400 mg ibuprofen tablet for the treatment of acute lower back or neck pain.
- Trial name
- NCT03003000
- Testing
- ibuprofen, caffeine
- Where
- 18 sites in Germany, Russia
- Volunteers
- 635 people
- Sponsor
- Boehringer Ingelheim
Patient Compliance
Actual Use Trial of Ibuprofen 400 mg
This is an open label, multicenter, 30 day study designed to mimic an OTC like environment in which subjects will use the product after making a purchase decision about ibuprofen 400 mg caplets based only on their reading of the…
- Trial name
- NCT02294019
- Testing
- Ibuprofen 400 mg caplet
- Where
- 25 sites in United States
- Volunteers
- 738 people
- Sponsor
- Pfizer
Pain
Topical Ibuprofen for Delayed Onset Mulscle Soreness
The objective of this study is to compare the efficacy and safety of Ibuprofen 5% Topical Gel versus placebo administered two or three times daily for the treatment of pain associated with delayed onset muscle soreness following…
- Trial name
- NCT01794923
- Testing
- IBU BID, IBU TID
- Where
- United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Pfizer
Fever
Safety, Efficacy, and Pharmacokinetic Study of Intravenous Ibuprofen in Pediatric Patients
The primary objective of the study is to determine the superiority of a single dose of intravenous ibuprofen compared to acetaminophen for the treatment of fever during the first two hours of treatment.
- Trial name
- NCT01002573
- Testing
- ibuprofen, acetaminophen
- Where
- 17 sites in United States
- Volunteers
- 118 people
- Sponsor
- Cumberland Pharmaceuticals
NSAID Related Gastric Irritation
Pilot Study of OXP001 and Brufen in Healthy Subjects
Oxford Pharmascience (the sponsor) is developing a new formulation of Ibuprofen (OXP001 - the study drug) which it is proposed will have less of the side effects than are currently reported with standard prescription strength…
- Trial name
- NCT02050958
- Testing
- OXP001, Ibuprofen
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Oxford Pharmascience Ltd
Osteoarthritis, Knee
Safety and Efficacy of Celecoxib Versus Placebo in the Treatment of Knee Osteoarthritis in Patients Who Were Unresponsive to Naproxen and Ibuprofen
To compare the efficacy and safety of celecoxib versus placebo for the treatment of knee osteoarthritis (OA) in patients who were unresponsive to prescription strength naproxen and ibuprofen or who could not tolerate prescription…
- Trial name
- NCT00638807
- Testing
- Celecoxib
- Where
- 33 sites in United States
- Volunteers
- 388 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Patent Ductus Arteriosus
Safety and Efficacy Study of Ibuprofen l-Lysine Solution in Premature Infants for Treatment of PDA
The purpose of this study is to determine the safety and effectiveness of ibuprofen l-lysine iv in premature infants in the early treatment of Patent Ductus Arteriosus.
- Trial name
- NCT00440804
- Testing
- ibuprofen l-lysine iv solution (NeoProfen (R) )
- Sponsor
- Farmacon
Primary Dysmenorrhea
Diagnostic and Therapeutic Potential of Substance P/ NK1R Receptor in Primary Dysmenorrhea
Dysmenorrhea is characterized as excruciating menstrual cramps of uterine origin and is one of the most prevalent gynecological illnesses.
- Trial name
- NCT06317064
- Testing
- Ibuprofen and Aprepitant
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lahore Medical Research Center, LLP
Back Pain
Glucosamine Sulphate, Ginger, Ginger-Avocado-Soya and Ginger-Ibuprofen for Chronic Back Pain
The main purpose of this study is to investigate the ability of some dietary supplement products to affect general joint health and life quality in a selected population with back pain.
- Trial name
- NCT00317655
- Testing
- Glucosamine sulphate, Ginger, Ginger-Avocado-Soya
- Where
- Denmark
- Volunteers
- 175 people
- Sponsor
- Ferrosan AS
Fever
Pilot Study Comparison Of Intravenous Ibuprofen And Intravenous Paracetamol In Management Of Pediatric Fever
Fever is one of the most common reasons children are brought to emergency departments. Treatment of fever with antipyretics is usually done simply to make children more comfortable, although in some circumstances, such as febrile…
- Trial name
- NCT04123717
- Testing
- Intravenous Ibuprofen
- Where
- Qatar
- Volunteers
- 147 people
- Sponsor
- Hamad Medical Corporation
Pain
Efficacy and Safety of Ibuprofen in Patients With Ankle Injuries
The objective of the study is to evaluate the efficacy and safety of Ibuprofen in patients with ankle injuries.
- Trial name
- NCT01562717
- Testing
- Ibuprofen
- Where
- Finland
- Volunteers
- 62 people
- Sponsor
- Orion Corporation, Orion Pharma
Healthy
Ibuprofen and Pseudoephedrine Comparative Pharmacokinetic Study
This comparative pharmacokinetic study is being conducted to provide supporting evidence for inclusion in dossiers to regulatory authorities for an Article 8(3) of Directive 2001/83/EC abridged application for ibuprofen and…
- Trial name
- NCT03184766
- Testing
- Test Nurofen Cold and Flu®, Ibuprofen and pseudoephedrine liquid capsules, Comparator 1 Nurofen Cold and Flu®, ibuprofen and pseudoephedrine tablets, Comparator 2 Nurofen Immedia 200 mg Weichkapseln, ibuprofen liquid capsules
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Pain
A Bioequivalence Study of Advil PM Liqui-Gels Minis (Ibuprofen/Diphenhydramine Hydrochloride 200 mg/25 mg) Compared to the Current Marketed Advil PM Liqui-Gels (Ibuprofen/Diphenhydramine Hydrochloride 200 mg/25 mg) in Healthy Adult Subjects Under Fasted Conditions
The purpose of this study is to support the submission of Advil PM Liqui-Gels Minis (ibuprofen/diphenhydramine hydrochloride 200 milligrams [mg]/25 mg) which is a size reduction of the currently marketed Advil PM Liqui-Gels, by…
- Trial name
- NCT05674721
- Testing
- Advil PM Liqui-Gels Minis, Advil PM Liqui-Gels
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- HALEON
Ductus Arteriosus, Patent
Paracetamol in Patent Ductus Arteriosus
The purpose of the study is to assess the efficacy and safety of paracetamol in comparison to ibuprofen in the treatment of patent ductus arteriosus (PDA) in preterm infants.
- Trial name
- NCT02422966
- Testing
- Paracetamol, Ibuprofen
- Where
- 5 sites in Italy
- Volunteers
- 110 people
- Sponsor
- Aziende Chimiche Riunite Angelini Francesco S.p.A